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The map label for this gene is glpR [H]

Identifier: 150398100

GI number: 150398100

Start: 3045500

End: 3046264

Strand: Direct

Name: glpR [H]

Synonym: Smed_2902

Alternate gene names: 150398100

Gene position: 3045500-3046264 (Clockwise)

Preceding gene: 150398091

Following gene: 150398101

Centisome position: 80.53

GC content: 58.3

Gene sequence:

>765_bases
ATGTACCTGACCGAACGACAGGCGGAGATCCTGGAGCTGGCGAAAGCGGAGGGCCGCGTACTGGTCGAAGACCTCGCCCA
GCGTTTTTCGGTGACACCCCAAACGATCCGCAAGGATCTGAACGATCTTTGCGATGCAAGAGTTTTGAACCGCATCCATG
GCGGCGCCATCTTTCCGAGCGGCAAGGAAAACGTCAAATACGAATCTCGCCGCCAGATCGCAGCGGCCGAGAAGCAGGCG
ATCGGACGCGCCGCGGCTAGCCTCATTCCGGACAATTCCTCGCTGTTCATCAATATCGGCACGACAACGGAAGCGGTCGG
AGAGGCACTTCTCGACCATCGGGAACTGATGGTCATCACCAACAATATAAACGTCGCCAACAGGTTGCGTGTGTTCCCCA
CGATCGAAGTGGTTATTGCCGGCGGGGTCGTACGCGGTTCGGACGGCGGCATCGTCGGGGAGGCCGCCGTCGATTTCATC
AAGCAGTTCAAGGTGGATTTCGCGGTGATCGGCGCCTCGGCGATCGACCCGGATGGCGCGCTTCTGGACTTCGACTACCG
CGAAGTGAAAGTGGCGCAGGCGATCATCGCCAATGCCCGCCATGTCATCCTGGTTTCGGATTCGACGAAATTCGAACGCA
CGGCGCCGGTGCGTATCGGTCATATCTCACAAGTGCAAACCTTCATTACCGATCGCTGCACCGTTGAAAATGTTCGCAAA
ATCTGTGCGGACCGGGATGTGCGGCTGCTGGAGACCGAGACTTGA

Upstream 100 bases:

>100_bases
GCCGCAATGAAAATCGAACGTGTTGGATATGCCCAAACACAAATTGCGCCACTTTCGTTTTTGCATATTATGAAAGAAAA
CGAAAAGCGAGGGGCGTTGA

Downstream 100 bases:

>100_bases
TCCGCCTTGGAACGCAAGGATAGTGTCGCCCAAACATTCGTTTGACATTCGAAATATTTTCGCTTTAACTGTTTTCACTT
TCGCGATTGCGTGGAATTGT

Product: DeoR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 254; Mature: 254

Protein sequence:

>254_residues
MYLTERQAEILELAKAEGRVLVEDLAQRFSVTPQTIRKDLNDLCDARVLNRIHGGAIFPSGKENVKYESRRQIAAAEKQA
IGRAAASLIPDNSSLFINIGTTTEAVGEALLDHRELMVITNNINVANRLRVFPTIEVVIAGGVVRGSDGGIVGEAAVDFI
KQFKVDFAVIGASAIDPDGALLDFDYREVKVAQAIIANARHVILVSDSTKFERTAPVRIGHISQVQTFITDRCTVENVRK
ICADRDVRLLETET

Sequences:

>Translated_254_residues
MYLTERQAEILELAKAEGRVLVEDLAQRFSVTPQTIRKDLNDLCDARVLNRIHGGAIFPSGKENVKYESRRQIAAAEKQA
IGRAAASLIPDNSSLFINIGTTTEAVGEALLDHRELMVITNNINVANRLRVFPTIEVVIAGGVVRGSDGGIVGEAAVDFI
KQFKVDFAVIGASAIDPDGALLDFDYREVKVAQAIIANARHVILVSDSTKFERTAPVRIGHISQVQTFITDRCTVENVRK
ICADRDVRLLETET
>Mature_254_residues
MYLTERQAEILELAKAEGRVLVEDLAQRFSVTPQTIRKDLNDLCDARVLNRIHGGAIFPSGKENVKYESRRQIAAAEKQA
IGRAAASLIPDNSSLFINIGTTTEAVGEALLDHRELMVITNNINVANRLRVFPTIEVVIAGGVVRGSDGGIVGEAAVDFI
KQFKVDFAVIGASAIDPDGALLDFDYREVKVAQAIIANARHVILVSDSTKFERTAPVRIGHISQVQTFITDRCTVENVRK
ICADRDVRLLETET

Specific function: Repressor of the glycerol-3-phosphate regulon [H]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789829, Length=249, Percent_Identity=47.7911646586345, Blast_Score=244, Evalue=3e-66,
Organism=Escherichia coli, GI87082344, Length=255, Percent_Identity=37.2549019607843, Blast_Score=181, Evalue=5e-47,
Organism=Escherichia coli, GI1789059, Length=228, Percent_Identity=30.7017543859649, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI226510968, Length=254, Percent_Identity=30.7086614173228, Blast_Score=104, Evalue=6e-24,
Organism=Escherichia coli, GI1788069, Length=252, Percent_Identity=27.3809523809524, Blast_Score=101, Evalue=5e-23,
Organism=Escherichia coli, GI1789519, Length=246, Percent_Identity=27.2357723577236, Blast_Score=98, Evalue=6e-22,
Organism=Escherichia coli, GI1790753, Length=230, Percent_Identity=26.5217391304348, Blast_Score=91, Evalue=7e-20,
Organism=Escherichia coli, GI1787540, Length=230, Percent_Identity=28.2608695652174, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1789170, Length=229, Percent_Identity=25.3275109170306, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1787063, Length=251, Percent_Identity=23.9043824701195, Blast_Score=79, Evalue=2e-16,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 27825; Mature: 27825

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYLTERQAEILELAKAEGRVLVEDLAQRFSVTPQTIRKDLNDLCDARVLNRIHGGAIFPS
CCCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCEECCC
GKENVKYESRRQIAAAEKQAIGRAAASLIPDNSSLFINIGTTTEAVGEALLDHRELMVIT
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHCCCEEEEEE
NNINVANRLRVFPTIEVVIAGGVVRGSDGGIVGEAAVDFIKQFKVDFAVIGASAIDPDGA
CCCCHHHHEEECCEEEEEEECCEEECCCCCEEHHHHHHHHHHHHHHHEEEECCCCCCCCC
LLDFDYREVKVAQAIIANARHVILVSDSTKFERTAPVRIGHISQVQTFITDRCTVENVRK
EEECCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCEEECCHHHHHHHHHCCCCHHHHHH
ICADRDVRLLETET
HHCCCCCEEEECCC
>Mature Secondary Structure
MYLTERQAEILELAKAEGRVLVEDLAQRFSVTPQTIRKDLNDLCDARVLNRIHGGAIFPS
CCCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCEECCC
GKENVKYESRRQIAAAEKQAIGRAAASLIPDNSSLFINIGTTTEAVGEALLDHRELMVIT
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHCCCEEEEEE
NNINVANRLRVFPTIEVVIAGGVVRGSDGGIVGEAAVDFIKQFKVDFAVIGASAIDPDGA
CCCCHHHHEEECCEEEEEEECCEEECCCCCEEHHHHHHHHHHHHHHHEEEECCCCCCCCC
LLDFDYREVKVAQAIIANARHVILVSDSTKFERTAPVRIGHISQVQTFITDRCTVENVRK
EEECCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCEEECCHHHHHHHHHCCCCHHHHHH
ICADRDVRLLETET
HHCCCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8752340; 10984043 [H]