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The map label for this gene is 150397852

Identifier: 150397852

GI number: 150397852

Start: 2758320

End: 2759345

Strand: Direct

Name: 150397852

Synonym: Smed_2654

Alternate gene names: NA

Gene position: 2758320-2759345 (Clockwise)

Preceding gene: 150397851

Following gene: 150397853

Centisome position: 72.93

GC content: 64.13

Gene sequence:

>1026_bases
ATGAGCGAAAGACTGGAAGATATCGCGGTTGCCATGGTCGCCAATGGCCGGGGCCTGCTCGCTGCCGACGAGTCAACCGC
AACGATCAAGAAGCGCTTCGACGGCATCGGCCTGGAATCGACAGAGACGTCCCGCCGCGACTACCGCGAGATGCTGCTGC
GCGCCGACGATGCGATGCGCGACTATATCTCCGGCGTCATTCTTTATGAGGAAACCCTGTTCCAGAACGCCGCCGACGGC
ACGTCGCTGGTCGACATCATCCGCAAGGCGGATTCGATCCCCGGCATCAAGGTCGATGCCGGTGCCAAGCCGATGGCACA
TTTCCCGAACGAAACCATCACCGAGGGCCTCGATGGGCTCGCCGCCCGGCTCGCCAAATACCATGAAGCCGGCGCCCGTT
TCGCCAAATGGCGCGGTGTGATCGCGATTTCCAACGCCTTGCCGAGCCGGGGCGCGATCAGGGCAAATGCCCATGCGCTC
GCCCGCTATGCGGCGCTCTGCCAGGAAGCGAAGATCGTGCCGATCGTCGAGCCGGAAGTGCTTATGGACGGCGCCCCCGG
CGACCACTCGATCGAGCGCTCGGAAGAAGTCACCGAATGGACCCTGCGCACCGTCTTCGAGGAGCTGGGCGAACTTCGCG
TCAAGCTCGAGGGCATGATACTGAAGCCGAGCATGGTGATCGACGGCAAGAAGGCGCGCAAAGCCTCAGTCGACGAGGTG
GCGGAACGCACCATCAAGATCCTGAAACGCACCGTGCCGGCCGCCGTCCCCGGCATCGCCTTCCTCTCCGGCGGCCAATC
GACGGAAGAGGCGACGGCCCATCTCTCGGCAATGAACGCTGCCCACGATCTGCCGTGGAAACTCACCTTCTCCTATGGCC
GGGCGCTACAGCAGGAGGCGCTCAATGCCTGGGGCGGCAAGGCGGAAAACGTCGCCGCCGGCCAGCGCGCCTTCACCCAC
CGGGCCAAGATGTGCAGCCTGGCTGCAAAGGGTAGCTGGACGAAGGACTTCGAGAGGGCTGCCTGA

Upstream 100 bases:

>100_bases
GCCTTCGTTCCTGCGGCGCGAGGACGCTTTCGCGCCTCCGGCCGAAAACTTGTTTCATCCGCTGGTCCATTGGGACCAGC
GTTGTTCGTAGGAGATAAAT

Downstream 100 bases:

>100_bases
GCGAAAAGATACCGGTAAGAGGGAGAGAGGAGAGGTCCGGCGGCAGCGATGCCGCCGGACCTCTACCTTTTTCGGACAAG
TAATTGTCAGGGAGACAAGT

Product: fructose-bisphosphate aldolase

Products: NA

Alternate protein names: Fructose-biphosphate aldolase class I; FBP aldolase [H]

Number of amino acids: Translated: 341; Mature: 340

Protein sequence:

>341_residues
MSERLEDIAVAMVANGRGLLAADESTATIKKRFDGIGLESTETSRRDYREMLLRADDAMRDYISGVILYEETLFQNAADG
TSLVDIIRKADSIPGIKVDAGAKPMAHFPNETITEGLDGLAARLAKYHEAGARFAKWRGVIAISNALPSRGAIRANAHAL
ARYAALCQEAKIVPIVEPEVLMDGAPGDHSIERSEEVTEWTLRTVFEELGELRVKLEGMILKPSMVIDGKKARKASVDEV
AERTIKILKRTVPAAVPGIAFLSGGQSTEEATAHLSAMNAAHDLPWKLTFSYGRALQQEALNAWGGKAENVAAGQRAFTH
RAKMCSLAAKGSWTKDFERAA

Sequences:

>Translated_341_residues
MSERLEDIAVAMVANGRGLLAADESTATIKKRFDGIGLESTETSRRDYREMLLRADDAMRDYISGVILYEETLFQNAADG
TSLVDIIRKADSIPGIKVDAGAKPMAHFPNETITEGLDGLAARLAKYHEAGARFAKWRGVIAISNALPSRGAIRANAHAL
ARYAALCQEAKIVPIVEPEVLMDGAPGDHSIERSEEVTEWTLRTVFEELGELRVKLEGMILKPSMVIDGKKARKASVDEV
AERTIKILKRTVPAAVPGIAFLSGGQSTEEATAHLSAMNAAHDLPWKLTFSYGRALQQEALNAWGGKAENVAAGQRAFTH
RAKMCSLAAKGSWTKDFERAA
>Mature_340_residues
SERLEDIAVAMVANGRGLLAADESTATIKKRFDGIGLESTETSRRDYREMLLRADDAMRDYISGVILYEETLFQNAADGT
SLVDIIRKADSIPGIKVDAGAKPMAHFPNETITEGLDGLAARLAKYHEAGARFAKWRGVIAISNALPSRGAIRANAHALA
RYAALCQEAKIVPIVEPEVLMDGAPGDHSIERSEEVTEWTLRTVFEELGELRVKLEGMILKPSMVIDGKKARKASVDEVA
ERTIKILKRTVPAAVPGIAFLSGGQSTEEATAHLSAMNAAHDLPWKLTFSYGRALQQEALNAWGGKAENVAAGQRAFTHR
AKMCSLAAKGSWTKDFERAA

Specific function: Unknown

COG id: COG3588

COG function: function code G; Fructose-1,6-bisphosphate aldolase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class I fructose-bisphosphate aldolase family [H]

Homologues:

Organism=Homo sapiens, GI34577112, Length=334, Percent_Identity=51.7964071856287, Blast_Score=326, Evalue=2e-89,
Organism=Homo sapiens, GI34577110, Length=334, Percent_Identity=51.7964071856287, Blast_Score=326, Evalue=2e-89,
Organism=Homo sapiens, GI4557305, Length=334, Percent_Identity=51.7964071856287, Blast_Score=326, Evalue=2e-89,
Organism=Homo sapiens, GI193794814, Length=334, Percent_Identity=51.7964071856287, Blast_Score=326, Evalue=2e-89,
Organism=Homo sapiens, GI4885063, Length=333, Percent_Identity=49.5495495495495, Blast_Score=313, Evalue=2e-85,
Organism=Homo sapiens, GI40354205, Length=333, Percent_Identity=48.6486486486487, Blast_Score=310, Evalue=1e-84,
Organism=Caenorhabditis elegans, GI25150450, Length=335, Percent_Identity=48.3582089552239, Blast_Score=314, Evalue=3e-86,
Organism=Caenorhabditis elegans, GI71983985, Length=333, Percent_Identity=48.948948948949, Blast_Score=311, Evalue=4e-85,
Organism=Caenorhabditis elegans, GI71983990, Length=235, Percent_Identity=46.8085106382979, Blast_Score=210, Evalue=9e-55,
Organism=Drosophila melanogaster, GI221459619, Length=335, Percent_Identity=51.3432835820895, Blast_Score=332, Evalue=2e-91,
Organism=Drosophila melanogaster, GI24650288, Length=335, Percent_Identity=51.3432835820895, Blast_Score=332, Evalue=2e-91,
Organism=Drosophila melanogaster, GI45553577, Length=334, Percent_Identity=51.1976047904192, Blast_Score=332, Evalue=2e-91,
Organism=Drosophila melanogaster, GI24650282, Length=334, Percent_Identity=51.1976047904192, Blast_Score=331, Evalue=4e-91,
Organism=Drosophila melanogaster, GI24650280, Length=334, Percent_Identity=51.1976047904192, Blast_Score=331, Evalue=4e-91,
Organism=Drosophila melanogaster, GI24650278, Length=334, Percent_Identity=51.1976047904192, Blast_Score=331, Evalue=4e-91,
Organism=Drosophila melanogaster, GI24650304, Length=336, Percent_Identity=43.75, Blast_Score=280, Evalue=1e-75,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000741
- InterPro:   IPR013785 [H]

Pfam domain/function: PF00274 Glycolytic [H]

EC number: =4.1.2.13 [H]

Molecular weight: Translated: 37004; Mature: 36872

Theoretical pI: Translated: 6.90; Mature: 6.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSERLEDIAVAMVANGRGLLAADESTATIKKRFDGIGLESTETSRRDYREMLLRADDAMR
CCCHHHHHHHHEEECCCEEEEECCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHH
DYISGVILYEETLFQNAADGTSLVDIIRKADSIPGIKVDAGAKPMAHFPNETITEGLDGL
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCEEECCCCCCHHHCCCHHHHHHHHHH
AARLAKYHEAGARFAKWRGVIAISNALPSRGAIRANAHALARYAALCQEAKIVPIVEPEV
HHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEECHHH
LMDGAPGDHSIERSEEVTEWTLRTVFEELGELRVKLEGMILKPSMVIDGKKARKASVDEV
HCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEECCCEEECCCEEECCCHHHHCCHHHH
AERTIKILKRTVPAAVPGIAFLSGGQSTEEATAHLSAMNAAHDLPWKLTFSYGRALQQEA
HHHHHHHHHHHHHHHCCCHHEECCCCCHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHH
LNAWGGKAENVAAGQRAFTHRAKMCSLAAKGSWTKDFERAA
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCC
>Mature Secondary Structure 
SERLEDIAVAMVANGRGLLAADESTATIKKRFDGIGLESTETSRRDYREMLLRADDAMR
CCHHHHHHHHEEECCCEEEEECCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHH
DYISGVILYEETLFQNAADGTSLVDIIRKADSIPGIKVDAGAKPMAHFPNETITEGLDGL
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCEEECCCCCCHHHCCCHHHHHHHHHH
AARLAKYHEAGARFAKWRGVIAISNALPSRGAIRANAHALARYAALCQEAKIVPIVEPEV
HHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEECHHH
LMDGAPGDHSIERSEEVTEWTLRTVFEELGELRVKLEGMILKPSMVIDGKKARKASVDEV
HCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEECCCEEECCCEEECCCHHHHCCHHHH
AERTIKILKRTVPAAVPGIAFLSGGQSTEEATAHLSAMNAAHDLPWKLTFSYGRALQQEA
HHHHHHHHHHHHHHHCCCHHEECCCCCHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHH
LNAWGGKAENVAAGQRAFTHRAKMCSLAAKGSWTKDFERAA
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]