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The map label for this gene is adhc1 [H]

Identifier: 150397773

GI number: 150397773

Start: 2671821

End: 2672864

Strand: Reverse

Name: adhc1 [H]

Synonym: Smed_2575

Alternate gene names: 150397773

Gene position: 2672864-2671821 (Counterclockwise)

Preceding gene: 150397775

Following gene: 150397770

Centisome position: 70.68

GC content: 61.88

Gene sequence:

>1044_bases
ATGGCCATTGCACGAGGATATGCGGCGACGGACGCTTCGAAGCCGCTCGCCCCCTTCACCTTCGAACGCCGCGAGCCGCG
CGACGACGACGTGGTGATCGACATCAAATATTGTGGCGTCTGCCATTCCGATATCCACCAGGCGCGTGACGAATGGGGCA
ACTCGACTTTTCCCATGGTTCCCGGTCACGAAATCGTCGGGCTCGTCAGGGCGGTCGGCTCCAAGGTCACGAAATTCAAG
ATCGGCGATCGGGTAGGGGTTGGCTGCTTCGTGGATTCCTGCACGACCTGCGCCACGCGCGATCTCGACCTGGAGCAGTA
CTTGCCCGGCCTTGTGGTCACATATAACGGCGTGGAGGCCGACGGGACTCCGACGCAGGGAGGTTATTCCGACCATATCG
TCGTCAAGGAGGGTTATGTGCTCTCCATTCCGGAGAACCTGCCGCTCGATGCAGCCGCACCGCTGCTTTGCGCCGGCATC
ACGCTCTATTCGCCGCTGCGTCACTGGGAGGCCGGCCCGGGCAAGAAGGTGGCGATCGTCGGCATGGGCGGCCTCGGCCA
CATGGGCGTGAAGCTCGCCCATGCGATGGGGGCGGAGGTCACGGTGCTCAGCCAGACGCTTTCCAAGAAGGAGGATGGGC
TCAAGCTCGGGGCCGATCACTACTACGCGACGAAGGATCCGGAGACGTTTACGAAGCTCGCGGGCAGCTTCGACCTCATC
ATCTGCACGGTCGCGGCCGAGATCGACTGGAACGCCTATCTCAACCTCCTGAAGATCGACGGCGATCTGGTGCTGGTCGG
CATTCCTGAGAATCCGGTTCCGGTCCATGCCTTCTCGCTCGTGCCGGCACGGCGCAGTATCTCCGGTTCGATGATCGGCT
CGATCAAGGAGACGCAGGAGATGCTGGATTTCTGCGGCGAGCACGGCATCGCTTCGGAGATCGAGATGATCGAGATCGGG
CAGATCAACGAGGCTTACGAACGCGTGGTGAGAAGCGACGTACGCTACCGCTTCGTCATCGACATGGCCTCGCTCAAGGC
CTGA

Upstream 100 bases:

>100_bases
GATCGAACTAACGCACTGCCCTCGTGAGGCAGCATAGTCCCGCCTGCCGCCTTCGGTCCATACCGACAGGCGCGACTTTC
CTACAGATGAGGACAGACCA

Downstream 100 bases:

>100_bases
TTTGCAGGGCCGCTGCCGTTGTCTCAAAGCAACGGCAGCGGCCCGTCATTCTTGATTTCCTCCATGACCGCATAGGTTCG
CGTCTCCTTGACGCCCGGGA

Product: alcohol dehydrogenase

Products: NA

Alternate protein names: Ms-ADHC 1 [H]

Number of amino acids: Translated: 347; Mature: 346

Protein sequence:

>347_residues
MAIARGYAATDASKPLAPFTFERREPRDDDVVIDIKYCGVCHSDIHQARDEWGNSTFPMVPGHEIVGLVRAVGSKVTKFK
IGDRVGVGCFVDSCTTCATRDLDLEQYLPGLVVTYNGVEADGTPTQGGYSDHIVVKEGYVLSIPENLPLDAAAPLLCAGI
TLYSPLRHWEAGPGKKVAIVGMGGLGHMGVKLAHAMGAEVTVLSQTLSKKEDGLKLGADHYYATKDPETFTKLAGSFDLI
ICTVAAEIDWNAYLNLLKIDGDLVLVGIPENPVPVHAFSLVPARRSISGSMIGSIKETQEMLDFCGEHGIASEIEMIEIG
QINEAYERVVRSDVRYRFVIDMASLKA

Sequences:

>Translated_347_residues
MAIARGYAATDASKPLAPFTFERREPRDDDVVIDIKYCGVCHSDIHQARDEWGNSTFPMVPGHEIVGLVRAVGSKVTKFK
IGDRVGVGCFVDSCTTCATRDLDLEQYLPGLVVTYNGVEADGTPTQGGYSDHIVVKEGYVLSIPENLPLDAAAPLLCAGI
TLYSPLRHWEAGPGKKVAIVGMGGLGHMGVKLAHAMGAEVTVLSQTLSKKEDGLKLGADHYYATKDPETFTKLAGSFDLI
ICTVAAEIDWNAYLNLLKIDGDLVLVGIPENPVPVHAFSLVPARRSISGSMIGSIKETQEMLDFCGEHGIASEIEMIEIG
QINEAYERVVRSDVRYRFVIDMASLKA
>Mature_346_residues
AIARGYAATDASKPLAPFTFERREPRDDDVVIDIKYCGVCHSDIHQARDEWGNSTFPMVPGHEIVGLVRAVGSKVTKFKI
GDRVGVGCFVDSCTTCATRDLDLEQYLPGLVVTYNGVEADGTPTQGGYSDHIVVKEGYVLSIPENLPLDAAAPLLCAGIT
LYSPLRHWEAGPGKKVAIVGMGGLGHMGVKLAHAMGAEVTVLSQTLSKKEDGLKLGADHYYATKDPETFTKLAGSFDLII
CTVAAEIDWNAYLNLLKIDGDLVLVGIPENPVPVHAFSLVPARRSISGSMIGSIKETQEMLDFCGEHGIASEIEMIEIGQ
INEAYERVVRSDVRYRFVIDMASLKA

Specific function: Prefers aldehydes over alcohols [H]

COG id: COG1064

COG function: function code R; Zn-dependent alcohol dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI262073058, Length=230, Percent_Identity=28.695652173913, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI71743840, Length=230, Percent_Identity=28.695652173913, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI71565154, Length=248, Percent_Identity=28.6290322580645, Blast_Score=69, Evalue=5e-12,
Organism=Escherichia coli, GI1786518, Length=345, Percent_Identity=54.2028985507246, Blast_Score=332, Evalue=2e-92,
Organism=Escherichia coli, GI87082401, Length=346, Percent_Identity=35.8381502890173, Blast_Score=216, Evalue=3e-57,
Organism=Escherichia coli, GI87081918, Length=323, Percent_Identity=25.6965944272446, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1788073, Length=264, Percent_Identity=26.1363636363636, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788075, Length=311, Percent_Identity=25.08038585209, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1790045, Length=260, Percent_Identity=25.3846153846154, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1788407, Length=202, Percent_Identity=27.7227722772277, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI87082125, Length=297, Percent_Identity=27.2727272727273, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI226510992, Length=268, Percent_Identity=26.1194029850746, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71988145, Length=325, Percent_Identity=27.6923076923077, Blast_Score=130, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI17562584, Length=337, Percent_Identity=26.7062314540059, Blast_Score=125, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI17562582, Length=326, Percent_Identity=26.9938650306748, Blast_Score=108, Evalue=6e-24,
Organism=Saccharomyces cerevisiae, GI6323980, Length=322, Percent_Identity=44.4099378881988, Blast_Score=229, Evalue=3e-61,
Organism=Saccharomyces cerevisiae, GI6319949, Length=328, Percent_Identity=40.2439024390244, Blast_Score=199, Evalue=7e-52,
Organism=Saccharomyces cerevisiae, GI6323961, Length=327, Percent_Identity=29.9694189602446, Blast_Score=139, Evalue=9e-34,
Organism=Saccharomyces cerevisiae, GI6319621, Length=328, Percent_Identity=30.1829268292683, Blast_Score=137, Evalue=3e-33,
Organism=Saccharomyces cerevisiae, GI6323729, Length=329, Percent_Identity=31.306990881459, Blast_Score=136, Evalue=5e-33,
Organism=Saccharomyces cerevisiae, GI6324486, Length=327, Percent_Identity=30.2752293577982, Blast_Score=134, Evalue=2e-32,
Organism=Saccharomyces cerevisiae, GI6319258, Length=306, Percent_Identity=25.8169934640523, Blast_Score=96, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6319257, Length=342, Percent_Identity=24.8538011695906, Blast_Score=81, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6320033, Length=363, Percent_Identity=26.4462809917355, Blast_Score=77, Evalue=3e-15,
Organism=Drosophila melanogaster, GI17137530, Length=216, Percent_Identity=28.7037037037037, Blast_Score=75, Evalue=8e-14,
Organism=Drosophila melanogaster, GI17737897, Length=202, Percent_Identity=28.7128712871287, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI17737895, Length=238, Percent_Identity=26.4705882352941, Blast_Score=65, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.1.1.2 [H]

Molecular weight: Translated: 37514; Mature: 37383

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: PS00059 ADH_ZINC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIARGYAATDASKPLAPFTFERREPRDDDVVIDIKYCGVCHSDIHQARDEWGNSTFPMV
CCCCCCCCCCCCCCCCCCCEECCCCCCCCCEEEEEEECCCCHHHHHHHHHHHCCCCCCCC
PGHEIVGLVRAVGSKVTKFKIGDRVGVGCFVDSCTTCATRDLDLEQYLPGLVVTYNGVEA
CCHHHHHHHHHHCCCCEEEECCCCCCCEEECCCCCHHHCCCCCHHHHCCCEEEEECCEEC
DGTPTQGGYSDHIVVKEGYVLSIPENLPLDAAAPLLCAGITLYSPLRHWEAGPGKKVAIV
CCCCCCCCCCCEEEEECCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEE
GMGGLGHMGVKLAHAMGAEVTVLSQTLSKKEDGLKLGADHYYATKDPETFTKLAGSFDLI
EECCCCHHHHHHHHHCCCCCEEHHHHHHCCCCCCEECCCCEEECCCHHHHHHHCCCCEEE
ICTVAAEIDWNAYLNLLKIDGDLVLVGIPENPVPVHAFSLVPARRSISGSMIGSIKETQE
EEEEEEECCHHHEEEEEEECCCEEEEECCCCCCCEEEEEECCCHHCCCCHHHHHHHHHHH
MLDFCGEHGIASEIEMIEIGQINEAYERVVRSDVRYRFVIDMASLKA
HHHHHCCCCCCCCEEEEEECCCHHHHHHHHHHCCEEEEEEEEHHHCC
>Mature Secondary Structure 
AIARGYAATDASKPLAPFTFERREPRDDDVVIDIKYCGVCHSDIHQARDEWGNSTFPMV
CCCCCCCCCCCCCCCCCCEECCCCCCCCCEEEEEEECCCCHHHHHHHHHHHCCCCCCCC
PGHEIVGLVRAVGSKVTKFKIGDRVGVGCFVDSCTTCATRDLDLEQYLPGLVVTYNGVEA
CCHHHHHHHHHHCCCCEEEECCCCCCCEEECCCCCHHHCCCCCHHHHCCCEEEEECCEEC
DGTPTQGGYSDHIVVKEGYVLSIPENLPLDAAAPLLCAGITLYSPLRHWEAGPGKKVAIV
CCCCCCCCCCCEEEEECCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEE
GMGGLGHMGVKLAHAMGAEVTVLSQTLSKKEDGLKLGADHYYATKDPETFTKLAGSFDLI
EECCCCHHHHHHHHHCCCCCEEHHHHHHCCCCCCEECCCCEEECCCHHHHHHHCCCCEEE
ICTVAAEIDWNAYLNLLKIDGDLVLVGIPENPVPVHAFSLVPARRSISGSMIGSIKETQE
EEEEEEECCHHHEEEEEEECCCEEEEECCCCCCCEEEEEECCCHHCCCCHHHHHHHHHHH
MLDFCGEHGIASEIEMIEIGQINEAYERVVRSDVRYRFVIDMASLKA
HHHHHCCCCCCCCEEEEEECCCHHHHHHHHHHCCEEEEEEEEHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11257547 [H]