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The map label for this gene is lrp [C]

Identifier: 150397775

GI number: 150397775

Start: 2674077

End: 2674574

Strand: Reverse

Name: lrp [C]

Synonym: Smed_2577

Alternate gene names: 150397775

Gene position: 2674574-2674077 (Counterclockwise)

Preceding gene: 150397778

Following gene: 150397773

Centisome position: 70.72

GC content: 61.45

Gene sequence:

>498_bases
TTGCACCGGCATTTTGTTTGTAATAACCGTCATTTTGCCGGCGCTTTCAATTCCGGCCGAAGGAGACGGAAAATCGACGC
TGTAGACAGAACAATCCTCAGCATTTTGAGCCGCGAGGCGCGCATTCCGATGAAGTCGCTGGCCGGGCGCATCGGTTTGT
CACGCAGCGCGACGGCAGAGCGCGTCGCACGGCTGGAGAAGGCCGGTGTCATCCGCGGCTACCGCGCCGATATCGGCCAG
CTGGAAGAAGGGCAGATCGAGGCCTTCCTCCTGGTGACGCTGCAGCGGACGCCTTCGCTTGGCGTGCTTGACCGGCTCGC
CGGGTTTTCCTCGGTCAGGCGGGTCTCCTCCGTCAGCGGTCAGCTCGACCTTATCGTGGAGGTGGAGGTCGCATCGATCA
ATGCGCTCAACGAGTTGCGCAACGAGGTTGCGCAACTCGACAATGTCGAGGATCTGACCACCTCGATCGTGCTGCGCCGC
GACATCGAGCGAGGCTGA

Upstream 100 bases:

>100_bases
TGAAATCGGGTGTCGTCTTCAGCATGTCGTTCATGGGAACCCTCGCTCTTGTCACGAGAGTTGCACGCCCGCCCGGCGGG
TGCACCAGTCATTTCGCCGG

Downstream 100 bases:

>100_bases
GCGGCTCTTCGAAGCGACCGCTACCGTATGCACAACCTCCTGAAAGCTCCCATTAACCCTCGCTCAGCATCTCCGCCTCG
CCGCCCGTGCGGCCGATGAG

Product: AsnC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 165; Mature: 165

Protein sequence:

>165_residues
MHRHFVCNNRHFAGAFNSGRRRRKIDAVDRTILSILSREARIPMKSLAGRIGLSRSATAERVARLEKAGVIRGYRADIGQ
LEEGQIEAFLLVTLQRTPSLGVLDRLAGFSSVRRVSSVSGQLDLIVEVEVASINALNELRNEVAQLDNVEDLTTSIVLRR
DIERG

Sequences:

>Translated_165_residues
MHRHFVCNNRHFAGAFNSGRRRRKIDAVDRTILSILSREARIPMKSLAGRIGLSRSATAERVARLEKAGVIRGYRADIGQ
LEEGQIEAFLLVTLQRTPSLGVLDRLAGFSSVRRVSSVSGQLDLIVEVEVASINALNELRNEVAQLDNVEDLTTSIVLRR
DIERG
>Mature_165_residues
MHRHFVCNNRHFAGAFNSGRRRRKIDAVDRTILSILSREARIPMKSLAGRIGLSRSATAERVARLEKAGVIRGYRADIGQ
LEEGQIEAFLLVTLQRTPSLGVLDRLAGFSSVRRVSSVSGQLDLIVEVEVASINALNELRNEVAQLDNVEDLTTSIVLRR
DIERG

Specific function: Mediates A Global Response To Leucine. Exogenous Leucine Affects The Expression Of A Number Of Different Operons; Lrp Mediates This Effect For At Least Some Of These Operons. For Example It Is Regulator Of The Branched-Chain Amino Acid Transport Genes. [

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787116, Length=144, Percent_Identity=31.9444444444444, Blast_Score=64, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011008
- InterPro:   IPR013196
- InterPro:   IPR000485
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01037 AsnC_trans_reg; PF08279 HTH_11 [H]

EC number: NA

Molecular weight: Translated: 18346; Mature: 18346

Theoretical pI: Translated: 11.16; Mature: 11.16

Prosite motif: PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHRHFVCNNRHFAGAFNSGRRRRKIDAVDRTILSILSREARIPMKSLAGRIGLSRSATAE
CCCCEEECCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCHHHH
RVARLEKAGVIRGYRADIGQLEEGQIEAFLLVTLQRTPSLGVLDRLAGFSSVRRVSSVSG
HHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCC
QLDLIVEVEVASINALNELRNEVAQLDNVEDLTTSIVLRRDIERG
CEEEEEEEEHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MHRHFVCNNRHFAGAFNSGRRRRKIDAVDRTILSILSREARIPMKSLAGRIGLSRSATAE
CCCCEEECCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCHHHH
RVARLEKAGVIRGYRADIGQLEEGQIEAFLLVTLQRTPSLGVLDRLAGFSSVRRVSSVSG
HHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCC
QLDLIVEVEVASINALNELRNEVAQLDNVEDLTTSIVLRRDIERG
CEEEEEEEEHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA