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The map label for this gene is xerD [H]

Identifier: 150397765

GI number: 150397765

Start: 2663698

End: 2664639

Strand: Direct

Name: xerD [H]

Synonym: Smed_2567

Alternate gene names: 150397765

Gene position: 2663698-2664639 (Clockwise)

Preceding gene: 150397764

Following gene: 150397766

Centisome position: 70.43

GC content: 62.95

Gene sequence:

>942_bases
ATGACGGATCTGTCGGGAGCACACCTCGAAGCCTTCCTGGAAATGATGAGCGCCGAGCGCGGAGCGGCCGTGAACACGCT
GCAATCCTATGAGCGGGACCTCAGGGACGCGCGTTCTTTCCTGCGCTCGCGCGGCGTGGGGCTTGTCGACGCCTCGGCCG
ACGATCTCCGAAGCTATCTCTCCCACCTCACGGGTGAGGGCTTCAAATCGTCGTCGCAAGCCCGGCGGCTGTCGGCCCTC
AGGCAATTCTACAAGTTTCTCTATGCGGAGGGGCTGCGCACGGATGAGCCGACCGGCATCCTTGACGCGCCGAAGAAAAA
CCGCGCGCTTCCCAAGACGCTCAGCATCGAAGACGTCACAAGGCTGATCGGCCAGGCGGAGACGGAAGCAGAAAAGGGCG
GTGAGGACGCCGTCGCGAAGCTGCGCATGCACGCACTGATCGAACTCCTCTACGCGACCGGCATGCGCGTCAGCGAGCTC
GTTTCGCTGCCGGCGAGCGTGCTTGCGCAAGACGGGCGTTTCCTCATAATTCGCGGCAAGGGTAACAAGGAAAGGCTCGT
ACCGTTGTCGCAGACGGCGATCCGGGCTATGCGGGCCTATGGCCAAGCACTGCACAGAGAGGCCGACGGCGCCGATAGCC
CCTGGTTGTTCCCCTCCTATGGCAGGAACGGGTATCTGCCGCGGCAGGTCTTCGCCCGCGACCTCAAGAGCCTCGCCGCA
CGTGCCGGAATTCGCGTCGCGGCGATCTCTCCGCACGTGCTGCGACACGCCTTCGCGAGCCATCTTCTCGCCAACGGCGC
CGACCTTCGCGCCGTGCAGGAACTGCTCGGCCATTCGGACATTTCCACCACACAAATCTATACGCATGTGCTGGAAGAAC
GGCTTCACGACCTCGTGCAAAGCCATCACCCCCTTGCCAAACAGGCGAAAAAGCAGGATTAG

Upstream 100 bases:

>100_bases
GCATGATCTATGGCTCGATGGTGGCGCTCGTCACCTTCGTCGACCCGGTTGAGCGGGACGTTACGGTGCGCATTCCCTCG
GAACGGATCAACAAGCCGCA

Downstream 100 bases:

>100_bases
GTCCGCCTAACGGAATGGATTGGCAGGGCGACCCCTGTCGAAAAATGATCGGAAACGCATCTGATGCACAATTATCTCGA
CTTCGAAAAACCCATCTCTG

Product: site-specific tyrosine recombinase XerD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 313; Mature: 312

Protein sequence:

>313_residues
MTDLSGAHLEAFLEMMSAERGAAVNTLQSYERDLRDARSFLRSRGVGLVDASADDLRSYLSHLTGEGFKSSSQARRLSAL
RQFYKFLYAEGLRTDEPTGILDAPKKNRALPKTLSIEDVTRLIGQAETEAEKGGEDAVAKLRMHALIELLYATGMRVSEL
VSLPASVLAQDGRFLIIRGKGNKERLVPLSQTAIRAMRAYGQALHREADGADSPWLFPSYGRNGYLPRQVFARDLKSLAA
RAGIRVAAISPHVLRHAFASHLLANGADLRAVQELLGHSDISTTQIYTHVLEERLHDLVQSHHPLAKQAKKQD

Sequences:

>Translated_313_residues
MTDLSGAHLEAFLEMMSAERGAAVNTLQSYERDLRDARSFLRSRGVGLVDASADDLRSYLSHLTGEGFKSSSQARRLSAL
RQFYKFLYAEGLRTDEPTGILDAPKKNRALPKTLSIEDVTRLIGQAETEAEKGGEDAVAKLRMHALIELLYATGMRVSEL
VSLPASVLAQDGRFLIIRGKGNKERLVPLSQTAIRAMRAYGQALHREADGADSPWLFPSYGRNGYLPRQVFARDLKSLAA
RAGIRVAAISPHVLRHAFASHLLANGADLRAVQELLGHSDISTTQIYTHVLEERLHDLVQSHHPLAKQAKKQD
>Mature_312_residues
TDLSGAHLEAFLEMMSAERGAAVNTLQSYERDLRDARSFLRSRGVGLVDASADDLRSYLSHLTGEGFKSSSQARRLSALR
QFYKFLYAEGLRTDEPTGILDAPKKNRALPKTLSIEDVTRLIGQAETEAEKGGEDAVAKLRMHALIELLYATGMRVSELV
SLPASVLAQDGRFLIIRGKGNKERLVPLSQTAIRAMRAYGQALHREADGADSPWLFPSYGRNGYLPRQVFARDLKSLAAR
AGIRVAAISPHVLRHAFASHLLANGADLRAVQELLGHSDISTTQIYTHVLEERLHDLVQSHHPLAKQAKKQD

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=309, Percent_Identity=44.6601941747573, Blast_Score=226, Evalue=1e-60,
Organism=Escherichia coli, GI1790244, Length=314, Percent_Identity=33.4394904458599, Blast_Score=152, Evalue=4e-38,
Organism=Escherichia coli, GI1790768, Length=175, Percent_Identity=33.1428571428571, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011932 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 34546; Mature: 34415

Theoretical pI: Translated: 9.77; Mature: 9.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDLSGAHLEAFLEMMSAERGAAVNTLQSYERDLRDARSFLRSRGVGLVDASADDLRSYL
CCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCHHHHHHHH
SHLTGEGFKSSSQARRLSALRQFYKFLYAEGLRTDEPTGILDAPKKNRALPKTLSIEDVT
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHH
RLIGQAETEAEKGGEDAVAKLRMHALIELLYATGMRVSELVSLPASVLAQDGRFLIIRGK
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHCCCCEEEEECC
GNKERLVPLSQTAIRAMRAYGQALHREADGADSPWLFPSYGRNGYLPRQVFARDLKSLAA
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
RAGIRVAAISPHVLRHAFASHLLANGADLRAVQELLGHSDISTTQIYTHVLEERLHDLVQ
HCCCEEEECCHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
SHHPLAKQAKKQD
CCCHHHHHHCCCC
>Mature Secondary Structure 
TDLSGAHLEAFLEMMSAERGAAVNTLQSYERDLRDARSFLRSRGVGLVDASADDLRSYL
CCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCHHHHHHHH
SHLTGEGFKSSSQARRLSALRQFYKFLYAEGLRTDEPTGILDAPKKNRALPKTLSIEDVT
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHH
RLIGQAETEAEKGGEDAVAKLRMHALIELLYATGMRVSELVSLPASVLAQDGRFLIIRGK
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHCCCCEEEEECC
GNKERLVPLSQTAIRAMRAYGQALHREADGADSPWLFPSYGRNGYLPRQVFARDLKSLAA
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
RAGIRVAAISPHVLRHAFASHLLANGADLRAVQELLGHSDISTTQIYTHVLEERLHDLVQ
HCCCEEEECCHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
SHHPLAKQAKKQD
CCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]