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The map label for this gene is accA [H]

Identifier: 150397766

GI number: 150397766

Start: 2664703

End: 2665656

Strand: Direct

Name: accA [H]

Synonym: Smed_2568

Alternate gene names: 150397766

Gene position: 2664703-2665656 (Clockwise)

Preceding gene: 150397765

Following gene: 150397767

Centisome position: 70.46

GC content: 60.17

Gene sequence:

>954_bases
ATGCACAATTATCTCGACTTCGAAAAACCCATCTCTGATCTCGAAGGCAAGATTCTCGAACTGAAGAAACTCGCCAGCGA
AGACGAGAGCGTCAACACATCAGACGAGATTGCCCGATTGGAAGGGCGCGTCCGCGATGCGATGGTTGAGATCTATTCCA
AGTTGTCCCCCTGGCAGAAGACTCAAGTCGCACGCCACCCCTCGCGTCCGCATTTCCTCGATTATGCGTCACGCCTCTTC
ACCGAGTTCACCCCGCTGGCCGGCGACCGGAACTTTGCCAATGACGATGCAATCCAGGCCGGGCTCGCCCGATTCCGCGG
CGCGCCCGTCGCCGTCATCGGTCAGGAGAAGGGCAACGACACCAAGTCGCGGATCAAGCACAATTTCGGCAGCCCTCGAC
CGGAAGGCTATCGCAAGGCAACACGGATCATGGAGATGGCCGACCGTTTCGGCCTGCCGCTGATCACGCTGGTCGATACC
GCGGGCGCCTATCCAGGTGTTAACGCGGAGGAGCGCGGCCAGGCCGAAGCGATCGCGCGCTCGACCGAAATGTGCCTCAA
CGTCAAGGTGCCGATCGTCACAGTGGTCATTGGAGAGGGCGGCTCAGGCGGCGCAATAGCCATTGCAACAGGCAACCGCG
TCTACATGCTGGAACATGCGATCTATAGCGTGATCTCACCGGAAGGTGCTGCCTCGATCCTTTGGCGCGACTCGACGCGA
GCCAAGGAGGCCGCGAGCAACATGAAGATCACCGCCGAAGACTTGAAGTCACTCGGCGTCATCGATGGAATAATTCCGGA
GCCGATCGGCGGGGGCCATCGCGATCCGGACGCGGTCATCAGCCGCACCGAAGCCGTGATCGGCGATGCCCTCAAAGAGC
TGTCCGCACGCAGTGGCGACGAATTGCGGTCCGACCGGCGGCAGAAATATCTGAACATCGGCCGTAATCTCTGA

Upstream 100 bases:

>100_bases
TCACCCCCTTGCCAAACAGGCGAAAAAGCAGGATTAGGTCCGCCTAACGGAATGGATTGGCAGGGCGACCCCTGTCGAAA
AATGATCGGAAACGCATCTG

Downstream 100 bases:

>100_bases
AAACCCTGGGAAAAAGCTCCGTCTTATCGCTCGTATCTGGCTTGTTCCGATCTGAACCATCGCGATTATCGGGAGCGTTC
GACAACCGGATTTGGACTAT

Product: acetyl-CoA carboxylase carboxyltransferase subunit alpha

Products: NA

Alternate protein names: ACCase subunit alpha; Acetyl-CoA carboxylase carboxyltransferase subunit alpha [H]

Number of amino acids: Translated: 317; Mature: 317

Protein sequence:

>317_residues
MHNYLDFEKPISDLEGKILELKKLASEDESVNTSDEIARLEGRVRDAMVEIYSKLSPWQKTQVARHPSRPHFLDYASRLF
TEFTPLAGDRNFANDDAIQAGLARFRGAPVAVIGQEKGNDTKSRIKHNFGSPRPEGYRKATRIMEMADRFGLPLITLVDT
AGAYPGVNAEERGQAEAIARSTEMCLNVKVPIVTVVIGEGGSGGAIAIATGNRVYMLEHAIYSVISPEGAASILWRDSTR
AKEAASNMKITAEDLKSLGVIDGIIPEPIGGGHRDPDAVISRTEAVIGDALKELSARSGDELRSDRRQKYLNIGRNL

Sequences:

>Translated_317_residues
MHNYLDFEKPISDLEGKILELKKLASEDESVNTSDEIARLEGRVRDAMVEIYSKLSPWQKTQVARHPSRPHFLDYASRLF
TEFTPLAGDRNFANDDAIQAGLARFRGAPVAVIGQEKGNDTKSRIKHNFGSPRPEGYRKATRIMEMADRFGLPLITLVDT
AGAYPGVNAEERGQAEAIARSTEMCLNVKVPIVTVVIGEGGSGGAIAIATGNRVYMLEHAIYSVISPEGAASILWRDSTR
AKEAASNMKITAEDLKSLGVIDGIIPEPIGGGHRDPDAVISRTEAVIGDALKELSARSGDELRSDRRQKYLNIGRNL
>Mature_317_residues
MHNYLDFEKPISDLEGKILELKKLASEDESVNTSDEIARLEGRVRDAMVEIYSKLSPWQKTQVARHPSRPHFLDYASRLF
TEFTPLAGDRNFANDDAIQAGLARFRGAPVAVIGQEKGNDTKSRIKHNFGSPRPEGYRKATRIMEMADRFGLPLITLVDT
AGAYPGVNAEERGQAEAIARSTEMCLNVKVPIVTVVIGEGGSGGAIAIATGNRVYMLEHAIYSVISPEGAASILWRDSTR
AKEAASNMKITAEDLKSLGVIDGIIPEPIGGGHRDPDAVISRTEAVIGDALKELSARSGDELRSDRRQKYLNIGRNL

Specific function: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-Co

COG id: COG0825

COG function: function code I; Acetyl-CoA carboxylase alpha subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AccA family [H]

Homologues:

Organism=Escherichia coli, GI1786382, Length=314, Percent_Identity=50.3184713375796, Blast_Score=324, Evalue=4e-90,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001095
- InterPro:   IPR011763 [H]

Pfam domain/function: PF03255 ACCA [H]

EC number: =6.4.1.2 [H]

Molecular weight: Translated: 34629; Mature: 34629

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: PS50989 COA_CT_CTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHNYLDFEKPISDLEGKILELKKLASEDESVNTSDEIARLEGRVRDAMVEIYSKLSPWQK
CCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHH
TQVARHPSRPHFLDYASRLFTEFTPLAGDRNFANDDAIQAGLARFRGAPVAVIGQEKGND
HHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCC
TKSRIKHNFGSPRPEGYRKATRIMEMADRFGLPLITLVDTAGAYPGVNAEERGQAEAIAR
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCHHCCHHHHHHH
STEMCLNVKVPIVTVVIGEGGSGGAIAIATGNRVYMLEHAIYSVISPEGAASILWRDSTR
HHHHHEEEECEEEEEEEECCCCCCEEEEEECCEEEEHHHHHHHHHCCCCCEEEEECCCHH
AKEAASNMKITAEDLKSLGVIDGIIPEPIGGGHRDPDAVISRTEAVIGDALKELSARSGD
HHHHHHCCEEEHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCH
ELRSDRRQKYLNIGRNL
HHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MHNYLDFEKPISDLEGKILELKKLASEDESVNTSDEIARLEGRVRDAMVEIYSKLSPWQK
CCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHH
TQVARHPSRPHFLDYASRLFTEFTPLAGDRNFANDDAIQAGLARFRGAPVAVIGQEKGND
HHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCC
TKSRIKHNFGSPRPEGYRKATRIMEMADRFGLPLITLVDTAGAYPGVNAEERGQAEAIAR
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCHHCCHHHHHHH
STEMCLNVKVPIVTVVIGEGGSGGAIAIATGNRVYMLEHAIYSVISPEGAASILWRDSTR
HHHHHEEEECEEEEEEEECCCCCCEEEEEECCEEEEHHHHHHHHHCCCCCEEEEECCCHH
AKEAASNMKITAEDLKSLGVIDGIIPEPIGGGHRDPDAVISRTEAVIGDALKELSARSGD
HHHHHHCCEEEHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCH
ELRSDRRQKYLNIGRNL
HHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]