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The map label for this gene is dgdR [H]

Identifier: 150397632

GI number: 150397632

Start: 2511623

End: 2512513

Strand: Direct

Name: dgdR [H]

Synonym: Smed_2432

Alternate gene names: 150397632

Gene position: 2511623-2512513 (Clockwise)

Preceding gene: 150397630

Following gene: 150397633

Centisome position: 66.41

GC content: 61.62

Gene sequence:

>891_bases
ATGGCCGAGTTCAACAGCCGGCGTCTGGAAATCGACGCGCTTCGCGCCCTATGGGCAATACGCCATCACGGTGGGATCAC
CCGCGCGGCTGAAGCGTTGGGTCTGTCACAATCGGCCGTCAGCCATAAGATCAAACGGCTGGAGACGAGCCTCGACTGCG
ACCTCCTCAGCCGCAGGTCCGGGGGTCCGGTCTTTACCTCGGCCGGCGAGGACTTGCTGGATTATGCCGGGCGCATCCTC
GGCCTGCATGACGAGGCACTGCTGAGCCTGTCGAAGACACAACTCGCGGGGCGTATCGCGCTCGGCCTGACCGAAGACAC
GACGTGCACGGACCTTGCCCGCATTCTCGGGCGGTTCCGCCGCCTGCATCCGCATGTCTCTGTCCGCATCAAGGTCCGCA
TGAGCTTGGTCCTGCGAGCGATGCTGGAACGCGGGGAACTCGACGCGGCAATCGTGCAGGTTTTTTCCCATGAAGTCCGC
CCCACCGACGTTGTTCTGTTTCGGGAGAACCTTCATTGGGTCAAGCACCCTGATCTATGCCTGCCGCAGAATGGACCTAT
ACCCTTCCTGTCCTTCGACGACGAATGCTTCTACCGTAAATGGGCGCTCGACGTCGGACAGGACGGAGGAACGATCCTCG
AAACCGTATTCGAATGTGCGAGCGCGGCAGGGATTGTCGCTGCGGTCAAGTCGGCGCTGGGCGTGGCACTTTTGAGCGAG
CGACATCTGCGCGCCGAGATGCAGATCGTGACCGACCGCCTGCCTGCCCCGCCTGCCCTGGTTTACGTGGTTCGTCGCGC
CAGAAAGGCCAGGATTCCCGCGCTCGATACTCTGATTGCCGAAATCGAACATGAAACCAGCCGGTATGGAGGGTTGATCC
TGACAGGCTGA

Upstream 100 bases:

>100_bases
CGATGAAAGCATGACAGTGCAGTCATCAATGTAATGCCCATTTGCAACACGGCCCGGGTGTGATTATGCAAACGGGAAAG
GTCACTCAATCAGGTTCGAC

Downstream 100 bases:

>100_bases
GCCTGCCGCCGGTTGAAGCCTTCCAAACTTGCGGATTCGTGAAGTCGGCTCGTGCGGACGAAGGGTGTCTTTCTAGACGA
GATCTAGCTCCGCCTGCCGG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: 2,2-dialkylglycine decarboxylase repressor [H]

Number of amino acids: Translated: 296; Mature: 295

Protein sequence:

>296_residues
MAEFNSRRLEIDALRALWAIRHHGGITRAAEALGLSQSAVSHKIKRLETSLDCDLLSRRSGGPVFTSAGEDLLDYAGRIL
GLHDEALLSLSKTQLAGRIALGLTEDTTCTDLARILGRFRRLHPHVSVRIKVRMSLVLRAMLERGELDAAIVQVFSHEVR
PTDVVLFRENLHWVKHPDLCLPQNGPIPFLSFDDECFYRKWALDVGQDGGTILETVFECASAAGIVAAVKSALGVALLSE
RHLRAEMQIVTDRLPAPPALVYVVRRARKARIPALDTLIAEIEHETSRYGGLILTG

Sequences:

>Translated_296_residues
MAEFNSRRLEIDALRALWAIRHHGGITRAAEALGLSQSAVSHKIKRLETSLDCDLLSRRSGGPVFTSAGEDLLDYAGRIL
GLHDEALLSLSKTQLAGRIALGLTEDTTCTDLARILGRFRRLHPHVSVRIKVRMSLVLRAMLERGELDAAIVQVFSHEVR
PTDVVLFRENLHWVKHPDLCLPQNGPIPFLSFDDECFYRKWALDVGQDGGTILETVFECASAAGIVAAVKSALGVALLSE
RHLRAEMQIVTDRLPAPPALVYVVRRARKARIPALDTLIAEIEHETSRYGGLILTG
>Mature_295_residues
AEFNSRRLEIDALRALWAIRHHGGITRAAEALGLSQSAVSHKIKRLETSLDCDLLSRRSGGPVFTSAGEDLLDYAGRILG
LHDEALLSLSKTQLAGRIALGLTEDTTCTDLARILGRFRRLHPHVSVRIKVRMSLVLRAMLERGELDAAIVQVFSHEVRP
TDVVLFRENLHWVKHPDLCLPQNGPIPFLSFDDECFYRKWALDVGQDGGTILETVFECASAAGIVAAVKSALGVALLSER
HLRAEMQIVTDRLPAPPALVYVVRRARKARIPALDTLIAEIEHETSRYGGLILTG

Specific function: Not Known, Does Not Seem To Act On The Proton Translocating NADH Dehydrogenase Genes (Nuoa-N) Which Are Part Of The Lrha Operon. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788626, Length=260, Percent_Identity=26.9230769230769, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI2367136, Length=292, Percent_Identity=27.7397260273973, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1787601, Length=177, Percent_Identity=30.5084745762712, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1787806, Length=242, Percent_Identity=25.2066115702479, Blast_Score=70, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32675; Mature: 32544

Theoretical pI: Translated: 7.97; Mature: 7.97

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEFNSRRLEIDALRALWAIRHHGGITRAAEALGLSQSAVSHKIKRLETSLDCDLLSRRS
CCCCCCCEEHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHHCCC
GGPVFTSAGEDLLDYAGRILGLHDEALLSLSKTQLAGRIALGLTEDTTCTDLARILGRFR
CCCEEECCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCEEEECCCCCCCHHHHHHHHHHHH
RLHPHVSVRIKVRMSLVLRAMLERGELDAAIVQVFSHEVRPTDVVLFRENLHWVKHPDLC
HHCCCEEEEEEHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCEEEEEECCCCEECCCCEE
LPQNGPIPFLSFDDECFYRKWALDVGQDGGTILETVFECASAAGIVAAVKSALGVALLSE
CCCCCCCCEEECCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RHLRAEMQIVTDRLPAPPALVYVVRRARKARIPALDTLIAEIEHETSRYGGLILTG
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCEEEEC
>Mature Secondary Structure 
AEFNSRRLEIDALRALWAIRHHGGITRAAEALGLSQSAVSHKIKRLETSLDCDLLSRRS
CCCCCCEEHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHHCCC
GGPVFTSAGEDLLDYAGRILGLHDEALLSLSKTQLAGRIALGLTEDTTCTDLARILGRFR
CCCEEECCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCEEEECCCCCCCHHHHHHHHHHHH
RLHPHVSVRIKVRMSLVLRAMLERGELDAAIVQVFSHEVRPTDVVLFRENLHWVKHPDLC
HHCCCEEEEEEHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCEEEEEECCCCEECCCCEE
LPQNGPIPFLSFDDECFYRKWALDVGQDGGTILETVFECASAAGIVAAVKSALGVALLSE
CCCCCCCCEEECCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RHLRAEMQIVTDRLPAPPALVYVVRRARKARIPALDTLIAEIEHETSRYGGLILTG
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2180928 [H]