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The map label for this gene is fabG [H]

Identifier: 150397601

GI number: 150397601

Start: 2476628

End: 2477488

Strand: Direct

Name: fabG [H]

Synonym: Smed_2401

Alternate gene names: 150397601

Gene position: 2476628-2477488 (Clockwise)

Preceding gene: 150397598

Following gene: 150397602

Centisome position: 65.49

GC content: 61.44

Gene sequence:

>861_bases
ATGATGTCCTACTCCGCCATAGCCAAGAACAACGTCGCCGTCGTTACCGGCGCCGCCTCCGGCATCGGCCTTGCCTCGGC
GCGTCGCTTCGCCAGTCTTGGAATGAAAGTCGTCCTGGCCGACCTCGGTGGCGAGAAGTTGCAGGCAGCCGCAGCCGAGG
TGTCGAAGGCAGCTCCTGAGGGCTCCGGCGATATCGCCGCAATCGCGACCGACGTGTCCCGTGCGGACGACCTCGTGGGG
CTGGCACGTGCGACGCGCGAACGGTTCGGGCACGTGCACGTCCTCATGAACAATGCCGGAACTCAACCGGGTAGTTCCAT
TTTCGGACCGCTTGAAAACTGGGAAGCGGTGATCGGCGTCAATCTGTGGGGGGTCATAAACGGCTCGCGCATCTTCACGC
CGGCGATGATTGCCCATGGCGAGCCAGCGCTCGTTATCAACACCGGTTCGAAACAAGGTATCACCACACCCCCCGGCGAC
CCCGCATACAACCTTTCGAAAGCCGGCGTGAAGGTCTTCACCGAGGCTCTGCAGCACGAATTGCGCAACACCGAAAACTG
TCAGGTCAATGCACATCTCCTGATCCCCGGCTTCGTCCACACCTCCCTCACCGCACATGGGCGTACGGAGAAACCCGCCG
GCGCCTGGACTCCGGAACAGACAGTGGATTTCATGATGGAGAGCCTGGCGCGCGGCGACTTCTACATTCTCTGCCCCGAC
AACGAAGTCGCACGTCCGACGGATGAAAAGCGCATCCTCTGGGCAGCCGGAGACATCGTCGAGAACCGGCAGCCGCTTTC
ACGCTGGCATTCGGACTATGGCGACGCTTTCCAGGCGTTTCTTGCCGAAACGAAGAACTGA

Upstream 100 bases:

>100_bases
ATCGAACCGGCCTAAAATCGTCGTGATCTCGTCCGCGTCATGGACTCGCCGGTGCCCGGACCCTATGTCTGCCTGATCCG
TTCCAAGCAGGATTGAAGCC

Downstream 100 bases:

>100_bases
GTACATTGCAAACGGTGCCGTCAGTAACGGCAGGAAGGGCTAAACCGTGACGAGCGGCATCCACCACATCACCCTGATCG
CCCGCAAGGTGCAGGCCAAT

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 286; Mature: 286

Protein sequence:

>286_residues
MMSYSAIAKNNVAVVTGAASGIGLASARRFASLGMKVVLADLGGEKLQAAAAEVSKAAPEGSGDIAAIATDVSRADDLVG
LARATRERFGHVHVLMNNAGTQPGSSIFGPLENWEAVIGVNLWGVINGSRIFTPAMIAHGEPALVINTGSKQGITTPPGD
PAYNLSKAGVKVFTEALQHELRNTENCQVNAHLLIPGFVHTSLTAHGRTEKPAGAWTPEQTVDFMMESLARGDFYILCPD
NEVARPTDEKRILWAAGDIVENRQPLSRWHSDYGDAFQAFLAETKN

Sequences:

>Translated_286_residues
MMSYSAIAKNNVAVVTGAASGIGLASARRFASLGMKVVLADLGGEKLQAAAAEVSKAAPEGSGDIAAIATDVSRADDLVG
LARATRERFGHVHVLMNNAGTQPGSSIFGPLENWEAVIGVNLWGVINGSRIFTPAMIAHGEPALVINTGSKQGITTPPGD
PAYNLSKAGVKVFTEALQHELRNTENCQVNAHLLIPGFVHTSLTAHGRTEKPAGAWTPEQTVDFMMESLARGDFYILCPD
NEVARPTDEKRILWAAGDIVENRQPLSRWHSDYGDAFQAFLAETKN
>Mature_286_residues
MMSYSAIAKNNVAVVTGAASGIGLASARRFASLGMKVVLADLGGEKLQAAAAEVSKAAPEGSGDIAAIATDVSRADDLVG
LARATRERFGHVHVLMNNAGTQPGSSIFGPLENWEAVIGVNLWGVINGSRIFTPAMIAHGEPALVINTGSKQGITTPPGD
PAYNLSKAGVKVFTEALQHELRNTENCQVNAHLLIPGFVHTSLTAHGRTEKPAGAWTPEQTVDFMMESLARGDFYILCPD
NEVARPTDEKRILWAAGDIVENRQPLSRWHSDYGDAFQAFLAETKN

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI31542939, Length=210, Percent_Identity=32.8571428571429, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI142976729, Length=246, Percent_Identity=28.4552845528455, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI20149619, Length=207, Percent_Identity=27.536231884058, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI109715829, Length=234, Percent_Identity=27.7777777777778, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI25282469, Length=242, Percent_Identity=26.0330578512397, Blast_Score=71, Evalue=9e-13,
Organism=Homo sapiens, GI40807363, Length=233, Percent_Identity=27.4678111587983, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI224922801, Length=168, Percent_Identity=33.3333333333333, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI4758504, Length=232, Percent_Identity=29.7413793103448, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI83715985, Length=188, Percent_Identity=32.9787234042553, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI19923817, Length=202, Percent_Identity=26.7326732673267, Blast_Score=65, Evalue=7e-11,
Organism=Homo sapiens, GI32483357, Length=223, Percent_Identity=27.8026905829596, Blast_Score=65, Evalue=1e-10,
Organism=Escherichia coli, GI87082100, Length=213, Percent_Identity=29.1079812206573, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1790717, Length=224, Percent_Identity=28.5714285714286, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI25147288, Length=202, Percent_Identity=36.1386138613861, Blast_Score=87, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI17555706, Length=201, Percent_Identity=31.8407960199005, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17564282, Length=200, Percent_Identity=30.5, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17561402, Length=199, Percent_Identity=28.643216080402, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17560332, Length=216, Percent_Identity=27.3148148148148, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI71994600, Length=207, Percent_Identity=28.5024154589372, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17538486, Length=228, Percent_Identity=25.4385964912281, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17570069, Length=229, Percent_Identity=24.8908296943231, Blast_Score=64, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17562908, Length=257, Percent_Identity=28.4046692607004, Blast_Score=64, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=203, Percent_Identity=31.0344827586207, Blast_Score=76, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24644339, Length=197, Percent_Identity=32.994923857868, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI21357041, Length=206, Percent_Identity=31.5533980582524, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI17737361, Length=234, Percent_Identity=29.0598290598291, Blast_Score=78, Evalue=8e-15,
Organism=Drosophila melanogaster, GI116007234, Length=206, Percent_Identity=32.5242718446602, Blast_Score=78, Evalue=9e-15,
Organism=Drosophila melanogaster, GI116007232, Length=181, Percent_Identity=34.8066298342541, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI28571526, Length=200, Percent_Identity=31.5, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI281364892, Length=222, Percent_Identity=27.9279279279279, Blast_Score=71, Evalue=9e-13,
Organism=Drosophila melanogaster, GI24639444, Length=207, Percent_Identity=31.8840579710145, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI23397609, Length=197, Percent_Identity=31.9796954314721, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24584752, Length=216, Percent_Identity=29.1666666666667, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI161076933, Length=212, Percent_Identity=29.2452830188679, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24584748, Length=212, Percent_Identity=29.2452830188679, Blast_Score=68, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24640442, Length=203, Percent_Identity=28.5714285714286, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI21358495, Length=241, Percent_Identity=21.1618257261411, Blast_Score=64, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 30403; Mature: 30403

Theoretical pI: Translated: 6.09; Mature: 6.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMSYSAIAKNNVAVVTGAASGIGLASARRFASLGMKVVLADLGGEKLQAAAAEVSKAAPE
CCCCHHHCCCCEEEEEECCCCCCHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHCCCC
GSGDIAAIATDVSRADDLVGLARATRERFGHVHVLMNNAGTQPGSSIFGPLENWEAVIGV
CCCCEEEEEECHHHHHHHHHHHHHHHHHHCEEEEEEECCCCCCCCCCCCCCCCCCEEEEE
NLWGVINGSRIFTPAMIAHGEPALVINTGSKQGITTPPGDPAYNLSKAGVKVFTEALQHE
EEEEEECCCEEECCHHHCCCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
LRNTENCQVNAHLLIPGFVHTSLTAHGRTEKPAGAWTPEQTVDFMMESLARGDFYILCPD
HCCCCCCEEEEEEEECCHHHHEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEECCC
NEVARPTDEKRILWAAGDIVENRQPLSRWHSDYGDAFQAFLAETKN
CCCCCCCCCCEEEEEECCHHHCCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MMSYSAIAKNNVAVVTGAASGIGLASARRFASLGMKVVLADLGGEKLQAAAAEVSKAAPE
CCCCHHHCCCCEEEEEECCCCCCHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHCCCC
GSGDIAAIATDVSRADDLVGLARATRERFGHVHVLMNNAGTQPGSSIFGPLENWEAVIGV
CCCCEEEEEECHHHHHHHHHHHHHHHHHHCEEEEEEECCCCCCCCCCCCCCCCCCEEEEE
NLWGVINGSRIFTPAMIAHGEPALVINTGSKQGITTPPGDPAYNLSKAGVKVFTEALQHE
EEEEEECCCEEECCHHHCCCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
LRNTENCQVNAHLLIPGFVHTSLTAHGRTEKPAGAWTPEQTVDFMMESLARGDFYILCPD
HCCCCCCEEEEEEEECCHHHHEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEECCC
NEVARPTDEKRILWAAGDIVENRQPLSRWHSDYGDAFQAFLAETKN
CCCCCCCCCCEEEEEECCHHHCCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]