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The map label for this gene is mraY [H]

Identifier: 150397286

GI number: 150397286

Start: 2142578

End: 2143678

Strand: Reverse

Name: mraY [H]

Synonym: Smed_2085

Alternate gene names: 150397286

Gene position: 2143678-2142578 (Counterclockwise)

Preceding gene: 150397287

Following gene: 150397285

Centisome position: 56.68

GC content: 59.95

Gene sequence:

>1101_bases
ATGCTGATCTGGCTTGTGGAACTGGCGGACCACTTTCAATTCTTCAATCTCTTTCGCTACATCACCTTCCGCACGGGCGC
GGCTCTGTTCACCTCTGCCTTGATCGTGTTCCTGTTCGGTCCGGCCATGATCGCTTCGTTGCGCATCCGTCAGGGCAAGG
GCCAGCCTATCCGCGCCGACGGCCCTCAGACGCACTTCAAGAAAGCCGGGACGCCGACCATGGGAGGGTTGATGATCCTC
GCGGGCATCGTGGTGTCCTCGCTGCTTTGGGCCGATCTATCCAGCATCTATGTCGTCTCGACGCTTCTGGTAACGCTGGG
TTTCGGCGCGATCGGCTTCTACGACGACTATCTCAAGGTGACGAAACAATCGGACAAAGGCTTCTCCGGCAAAGCCCGGC
TTGGCATCGAGTTCGTGATCGCCTCGATCGCCGTCTTCTTCATGATGCAGGCTGCGCTTTCGGCAGGGGCGGCGGGCTCC
ACTTTCGGGTCATCGGTGACCTTTCCATTCTTCAAGGACCTGATGCTCAATCTCGGCTATTTCTTCGTGCTGTTCGGCGG
CTTCGTCATCGTCGGCGCGGGAAATTCCGTAAATCTGACCGATGGCCTGGACGGGCTCGCGATCGTCCCTGTCATGATCG
CCTCGGCCGCGTTCGGGCTGATCGCCTATCTCGCCGGCAACGCTGTCTTTGCCAACTACCTGCAGATCCATTTCGTGCCC
GGCACCGGCGAACTCGCGGTGATCCTCGGCGCGGTGATCGGCGCAGGCCTTGGCTTCCTGTGGTTCAACGCGCCGCCCGC
CGCGATCTTCATGGGCGACACCGGTTCGCTTGCCCTCGGCGGTCTCATAGGCACCGTCGCCGTCGCAACCAAGCACGAGA
TCGTCATGGTCATCATCGGCGGGCTCTTTGTCATGGAGACATTGTCTGTCATCATTCAGGTCTTCTGGTTCAAGCGCACC
GGGCACCGGGTGTTCCTGATGGCACCGATCCACCATCACTTCGAGAAGAAGGGCTGGACGGAAAGCCAGGTGGTGATCCG
CTTCTGGATCATCGCCGTGATCCTTGCGATGGTCGGTCTCTCGACGCTGAAGCTTCGGTGA

Upstream 100 bases:

>100_bases
GGGAAATGGCCTAACATAGTCGAACGCAAGCGGATATCTTCTGGCAGATGATTCTGTTTGGACGATGTCCTGATATAAAC
TTCCGGGGGAAAGGTCCCTT

Downstream 100 bases:

>100_bases
GCGCGATGATCCCGGTCACTTCATTCAAGGGTAGGAAGGTCGCACTCTTCGGGCTGGGCGGCTCCGGACTGGCGACCGCC
CAGGCGCTCGTTGCAGGCGG

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase [H]

Number of amino acids: Translated: 366; Mature: 366

Protein sequence:

>366_residues
MLIWLVELADHFQFFNLFRYITFRTGAALFTSALIVFLFGPAMIASLRIRQGKGQPIRADGPQTHFKKAGTPTMGGLMIL
AGIVVSSLLWADLSSIYVVSTLLVTLGFGAIGFYDDYLKVTKQSDKGFSGKARLGIEFVIASIAVFFMMQAALSAGAAGS
TFGSSVTFPFFKDLMLNLGYFFVLFGGFVIVGAGNSVNLTDGLDGLAIVPVMIASAAFGLIAYLAGNAVFANYLQIHFVP
GTGELAVILGAVIGAGLGFLWFNAPPAAIFMGDTGSLALGGLIGTVAVATKHEIVMVIIGGLFVMETLSVIIQVFWFKRT
GHRVFLMAPIHHHFEKKGWTESQVVIRFWIIAVILAMVGLSTLKLR

Sequences:

>Translated_366_residues
MLIWLVELADHFQFFNLFRYITFRTGAALFTSALIVFLFGPAMIASLRIRQGKGQPIRADGPQTHFKKAGTPTMGGLMIL
AGIVVSSLLWADLSSIYVVSTLLVTLGFGAIGFYDDYLKVTKQSDKGFSGKARLGIEFVIASIAVFFMMQAALSAGAAGS
TFGSSVTFPFFKDLMLNLGYFFVLFGGFVIVGAGNSVNLTDGLDGLAIVPVMIASAAFGLIAYLAGNAVFANYLQIHFVP
GTGELAVILGAVIGAGLGFLWFNAPPAAIFMGDTGSLALGGLIGTVAVATKHEIVMVIIGGLFVMETLSVIIQVFWFKRT
GHRVFLMAPIHHHFEKKGWTESQVVIRFWIIAVILAMVGLSTLKLR
>Mature_366_residues
MLIWLVELADHFQFFNLFRYITFRTGAALFTSALIVFLFGPAMIASLRIRQGKGQPIRADGPQTHFKKAGTPTMGGLMIL
AGIVVSSLLWADLSSIYVVSTLLVTLGFGAIGFYDDYLKVTKQSDKGFSGKARLGIEFVIASIAVFFMMQAALSAGAAGS
TFGSSVTFPFFKDLMLNLGYFFVLFGGFVIVGAGNSVNLTDGLDGLAIVPVMIASAAFGLIAYLAGNAVFANYLQIHFVP
GTGELAVILGAVIGAGLGFLWFNAPPAAIFMGDTGSLALGGLIGTVAVATKHEIVMVIIGGLFVMETLSVIIQVFWFKRT
GHRVFLMAPIHHHFEKKGWTESQVVIRFWIIAVILAMVGLSTLKLR

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan [H]

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786275, Length=372, Percent_Identity=50.5376344086022, Blast_Score=348, Evalue=3e-97,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480 [H]

Pfam domain/function: PF00953 Glycos_transf_4; PF10555 MraY_sig1 [H]

EC number: =2.7.8.13 [H]

Molecular weight: Translated: 39256; Mature: 39256

Theoretical pI: Translated: 10.02; Mature: 10.02

Prosite motif: PS01347 MRAY_1 ; PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIWLVELADHFQFFNLFRYITFRTGAALFTSALIVFLFGPAMIASLRIRQGKGQPIRAD
CEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
GPQTHFKKAGTPTMGGLMILAGIVVSSLLWADLSSIYVVSTLLVTLGFGAIGFYDDYLKV
CCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
TKQSDKGFSGKARLGIEFVIASIAVFFMMQAALSAGAAGSTFGSSVTFPFFKDLMLNLGY
HCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHH
FFVLFGGFVIVGAGNSVNLTDGLDGLAIVPVMIASAAFGLIAYLAGNAVFANYLQIHFVP
HHHHHCCEEEEECCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHEEEEEEEEEEC
GTGELAVILGAVIGAGLGFLWFNAPPAAIFMGDTGSLALGGLIGTVAVATKHEIVMVIIG
CCCHHHHHHHHHHHCCHHEEEECCCCCEEEECCCCCHHHHHHHHHHHHHCCCCEEEHHHH
GLFVMETLSVIIQVFWFKRTGHRVFLMAPIHHHFEKKGWTESQVVIRFWIIAVILAMVGL
HHHHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCH
STLKLR
HHHCCC
>Mature Secondary Structure
MLIWLVELADHFQFFNLFRYITFRTGAALFTSALIVFLFGPAMIASLRIRQGKGQPIRAD
CEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
GPQTHFKKAGTPTMGGLMILAGIVVSSLLWADLSSIYVVSTLLVTLGFGAIGFYDDYLKV
CCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
TKQSDKGFSGKARLGIEFVIASIAVFFMMQAALSAGAAGSTFGSSVTFPFFKDLMLNLGY
HCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHH
FFVLFGGFVIVGAGNSVNLTDGLDGLAIVPVMIASAAFGLIAYLAGNAVFANYLQIHFVP
HHHHHCCEEEEECCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHEEEEEEEEEEC
GTGELAVILGAVIGAGLGFLWFNAPPAAIFMGDTGSLALGGLIGTVAVATKHEIVMVIIG
CCCHHHHHHHHHHHCCHHEEEECCCCCEEEECCCCCHHHHHHHHHHHHHCCCCEEEHHHH
GLFVMETLSVIIQVFWFKRTGHRVFLMAPIHHHFEKKGWTESQVVIRFWIIAVILAMVGL
HHHHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCH
STLKLR
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11481430; 7926844 [H]