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The map label for this gene is ntrY [H]

Identifier: 150396310

GI number: 150396310

Start: 1159461

End: 1161734

Strand: Direct

Name: ntrY [H]

Synonym: Smed_1091

Alternate gene names: 150396310

Gene position: 1159461-1161734 (Clockwise)

Preceding gene: 150396309

Following gene: 150396311

Centisome position: 30.66

GC content: 62.75

Gene sequence:

>2274_bases
ATGGTGGATGGAATGGCCTTGCCATTGGGCACGGAGGACGGAGTCACTGCTGCCCAGGACAGGCGAGCCTCATTCGCCTT
GCCGGGGCTCATGCTTGCCACCGGTGCCCTGGTCTGCGCCACCTTGTCGCTGCTCGTTCTTCTTGGCCTGACCCCGGTCC
GGCCTGAGAGAAACATCGTTATCGCCTGTGCCGGCGTCAACGGCCTGTTCGTCGTGGGGCTGATCTATCTCATCGCCCGC
GAGATATTCAGGCTGCTCAGGGCACGCAGCAAAGGCAGGGCCGCCGCGCGCCTGCATGTCCGCATCGTCGCACTCTTTTC
GATCGTCGCGATCACGCCGGCCATCCTCGTCGCCATCTTCGCCAGCATCACTCTCGATGTGGGCCTCGACCGCTGGTTCT
CGCTGCGTACGCAGGCGATCGTCCGTTCCTCGCTGAACGTCGCCCAGGCCTATGTCCTTGAGAATGCCAGTTACCTGCAG
GGCCAGACGGTCTCGATGGCCAACGATCTGGAGCGCAATCGTCAGCTCTACAGCCTCGACCGCACAGGCTTCGTCGAGCT
GATGACGCGGCAGGCGAGGGGCAGAGGCATGCTTGGCGCTTTCCTCGTGCGCGCTGACGGCAGCGCCATACTTCAGGCCA
ATATCTCGACCGACCGTCCGCTGCCTGCGATCCCGCAGGACGCGCTGAAAAGCACTGTCTCGGGTCAACCGACCCTCATT
CCTCCCGGCGTGACCAATCTGGTGGGAGCGGTCATTCCGCTGGAGAACATCCCCGGTACCTATCTCTACACCGTCCGCAA
CGTCGATCCCGAAGTCATGCGGTCGATGCGGCTGATGGAAGAGAACACTGCGGAATACAAGACCTTGGAGGCCGGGCGCA
CTTCCCTTCAGATCGCCTTCGGCGTCCTTTACATCGGCTTCGCCCTGATCGTGCTGCTGGCGGCGATCTGGACCGCCATC
GCGGTCGCCGACCGCATCGTGCGTCCGATCCGCCAGTTGATCGGCGCGGCTGACAGCGTCGCTTCCGGCAATCTCGACGT
CGTCGTACCCGTGCGCGCGGTCGACGGCGACGTCGGCAATCTGTCGCGCACGTTCAACAAGATGGTGAGCGAAATCCGGA
CGCAGCAGGATCAAATTCTCGTAGCGAAGGACGAGGTCGACCAGCGCCGCCGGTTTATCGAGGCCGTGCTTTCCGGCGTG
ACGGCGGCAGTCATCGGCGTCGGCAGGGATCGTCGCATCACCATTTTCAATCCGTCTTCGGAAGGGGTGCTCAGGAAAGC
GGCGCCGGGGCTGATCGGCGCGCGGCTAAGTGATGTGGCCCCGGAAATCGAAGCGGTGCTCGTGGAGGCGGAGAGCCGCT
ACCGCAACGACTACCGCAAGCAGATCAACATCATGCGCGGCGGGACCGAGCGTACGATGAATGTTCAGGTGACGCAGGAA
GAAGGTGATGAGTCGCATGGTTCCTATGTGATCACCATCGACGACATCACCGATCTGGTCATTGCGCAGCGCTCCACCGC
CTGGGCGGATGTCGCTCGCCGCATCGCGCACGAGATCAAGAACCCCCTGACGCCGATTCAGCTTTCCGCCGAGCGGCTGA
AGCGCCGCTACGGCAAACAGATCAATCAGGACGACAGAGCGGTTTTCGACCAGTGTACCGAAACGATCGTGCGCCAGGTC
GAGGATATCGGCCGGATGGTCGATGAGTTCTCCGCCTTTGCGCGCATGCCCAAGCCGACGAAGGAAGAGTCCGATCTGCG
GGCCATCCTCAAGGACGCCGTATTCCTGCGCGAGATGGGCAACAATCACATCGCCTTCATCCGGGATTTCGGCGACGAAC
CGCTCGAGGGCCAGTTCGACGGCCGCATGCTGGGCCAGGCATTTGGTAACCTGGTCAAGAACGCCGTGGAATCGATCGAA
GCCGTCCCCGCGGGGTCGTCGCGAGGTGCGCCGACGGTGGTCATTCGATCCCGTCGCGATGATGCGACCGGCCGTTTCGT
GGTCGACGTCGTCGACAACGGCAAGGGGCTTCCGACCGAGAACCGGCACCGGATTCTCGAGCCTTACATGACCATGCGGG
AGAAGGGCACCGGTCTCGGCCTCGCTATCGTCAAGAAAATCATCGAGGACCACGGCGGGCAACTGGAGCTGCACGACGCA
CCGTCGGATTTCGACGGCGGCGCCGGGGCGATGATCCGGGTGATCCTGCCGCCTGCCGGCGAGACCGGCGGTGAACATAA
TTTGAAGGATAAGGGTAATTTCAATGGCGGCTGA

Upstream 100 bases:

>100_bases
CCGCATCCGATGGGGTGCGGCGCCGCAGGTTCGATATCTCGGTCCGGAACGCAGGCATGTGCCGGTGTCGTCGGTACGCC
GGTTTGGGGAAGCACTTTTC

Downstream 100 bases:

>100_bases
TATTCTGGTTGTAGATGACGAGGAGGACATTCGCGAGATCGTCTCGGGAATCCTCTCTGACGAAGGCCATGAGACGCGCA
CCGCCTTCGACAGCGAGAGT

Product: multi-sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 757; Mature: 757

Protein sequence:

>757_residues
MVDGMALPLGTEDGVTAAQDRRASFALPGLMLATGALVCATLSLLVLLGLTPVRPERNIVIACAGVNGLFVVGLIYLIAR
EIFRLLRARSKGRAAARLHVRIVALFSIVAITPAILVAIFASITLDVGLDRWFSLRTQAIVRSSLNVAQAYVLENASYLQ
GQTVSMANDLERNRQLYSLDRTGFVELMTRQARGRGMLGAFLVRADGSAILQANISTDRPLPAIPQDALKSTVSGQPTLI
PPGVTNLVGAVIPLENIPGTYLYTVRNVDPEVMRSMRLMEENTAEYKTLEAGRTSLQIAFGVLYIGFALIVLLAAIWTAI
AVADRIVRPIRQLIGAADSVASGNLDVVVPVRAVDGDVGNLSRTFNKMVSEIRTQQDQILVAKDEVDQRRRFIEAVLSGV
TAAVIGVGRDRRITIFNPSSEGVLRKAAPGLIGARLSDVAPEIEAVLVEAESRYRNDYRKQINIMRGGTERTMNVQVTQE
EGDESHGSYVITIDDITDLVIAQRSTAWADVARRIAHEIKNPLTPIQLSAERLKRRYGKQINQDDRAVFDQCTETIVRQV
EDIGRMVDEFSAFARMPKPTKEESDLRAILKDAVFLREMGNNHIAFIRDFGDEPLEGQFDGRMLGQAFGNLVKNAVESIE
AVPAGSSRGAPTVVIRSRRDDATGRFVVDVVDNGKGLPTENRHRILEPYMTMREKGTGLGLAIVKKIIEDHGGQLELHDA
PSDFDGGAGAMIRVILPPAGETGGEHNLKDKGNFNGG

Sequences:

>Translated_757_residues
MVDGMALPLGTEDGVTAAQDRRASFALPGLMLATGALVCATLSLLVLLGLTPVRPERNIVIACAGVNGLFVVGLIYLIAR
EIFRLLRARSKGRAAARLHVRIVALFSIVAITPAILVAIFASITLDVGLDRWFSLRTQAIVRSSLNVAQAYVLENASYLQ
GQTVSMANDLERNRQLYSLDRTGFVELMTRQARGRGMLGAFLVRADGSAILQANISTDRPLPAIPQDALKSTVSGQPTLI
PPGVTNLVGAVIPLENIPGTYLYTVRNVDPEVMRSMRLMEENTAEYKTLEAGRTSLQIAFGVLYIGFALIVLLAAIWTAI
AVADRIVRPIRQLIGAADSVASGNLDVVVPVRAVDGDVGNLSRTFNKMVSEIRTQQDQILVAKDEVDQRRRFIEAVLSGV
TAAVIGVGRDRRITIFNPSSEGVLRKAAPGLIGARLSDVAPEIEAVLVEAESRYRNDYRKQINIMRGGTERTMNVQVTQE
EGDESHGSYVITIDDITDLVIAQRSTAWADVARRIAHEIKNPLTPIQLSAERLKRRYGKQINQDDRAVFDQCTETIVRQV
EDIGRMVDEFSAFARMPKPTKEESDLRAILKDAVFLREMGNNHIAFIRDFGDEPLEGQFDGRMLGQAFGNLVKNAVESIE
AVPAGSSRGAPTVVIRSRRDDATGRFVVDVVDNGKGLPTENRHRILEPYMTMREKGTGLGLAIVKKIIEDHGGQLELHDA
PSDFDGGAGAMIRVILPPAGETGGEHNLKDKGNFNGG
>Mature_757_residues
MVDGMALPLGTEDGVTAAQDRRASFALPGLMLATGALVCATLSLLVLLGLTPVRPERNIVIACAGVNGLFVVGLIYLIAR
EIFRLLRARSKGRAAARLHVRIVALFSIVAITPAILVAIFASITLDVGLDRWFSLRTQAIVRSSLNVAQAYVLENASYLQ
GQTVSMANDLERNRQLYSLDRTGFVELMTRQARGRGMLGAFLVRADGSAILQANISTDRPLPAIPQDALKSTVSGQPTLI
PPGVTNLVGAVIPLENIPGTYLYTVRNVDPEVMRSMRLMEENTAEYKTLEAGRTSLQIAFGVLYIGFALIVLLAAIWTAI
AVADRIVRPIRQLIGAADSVASGNLDVVVPVRAVDGDVGNLSRTFNKMVSEIRTQQDQILVAKDEVDQRRRFIEAVLSGV
TAAVIGVGRDRRITIFNPSSEGVLRKAAPGLIGARLSDVAPEIEAVLVEAESRYRNDYRKQINIMRGGTERTMNVQVTQE
EGDESHGSYVITIDDITDLVIAQRSTAWADVARRIAHEIKNPLTPIQLSAERLKRRYGKQINQDDRAVFDQCTETIVRQV
EDIGRMVDEFSAFARMPKPTKEESDLRAILKDAVFLREMGNNHIAFIRDFGDEPLEGQFDGRMLGQAFGNLVKNAVESIE
AVPAGSSRGAPTVVIRSRRDDATGRFVVDVVDNGKGLPTENRHRILEPYMTMREKGTGLGLAIVKKIIEDHGGQLELHDA
PSDFDGGAGAMIRVILPPAGETGGEHNLKDKGNFNGG

Specific function: Member of the two-component regulatory system ntrY/ntrX involved in nitrogen level control. Probably activates ntrX by phosphorylation [H]

COG id: COG5000

COG function: function code T; Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=425, Percent_Identity=22.3529411764706, Blast_Score=103, Evalue=4e-23,
Organism=Escherichia coli, GI1790300, Length=224, Percent_Identity=27.6785714285714, Blast_Score=76, Evalue=8e-15,
Organism=Escherichia coli, GI1790436, Length=237, Percent_Identity=25.3164556962025, Blast_Score=73, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR017232 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 82409; Mature: 82409

Theoretical pI: Translated: 7.26; Mature: 7.26

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVDGMALPLGTEDGVTAAQDRRASFALPGLMLATGALVCATLSLLVLLGLTPVRPERNIV
CCCCCCCCCCCCCCCCHHHHCCCHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEE
IACAGVNGLFVVGLIYLIAREIFRLLRARSKGRAAARLHVRIVALFSIVAITPAILVAIF
EEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASITLDVGLDRWFSLRTQAIVRSSLNVAQAYVLENASYLQGQTVSMANDLERNRQLYSLD
HHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHCCCEEECC
RTGFVELMTRQARGRGMLGAFLVRADGSAILQANISTDRPLPAIPQDALKSTVSGQPTLI
CCHHHHHHHHHHCCCCCCEEEEEECCCCEEEEEECCCCCCCCCCCHHHHHHHCCCCCCCC
PPGVTNLVGAVIPLENIPGTYLYTVRNVDPEVMRSMRLMEENTAEYKTLEAGRTSLQIAF
CCCHHHHHHHHHCCCCCCCCEEEEEECCCHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHH
GVLYIGFALIVLLAAIWTAIAVADRIVRPIRQLIGAADSVASGNLDVVVPVRAVDGDVGN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEECCCCCHH
LSRTFNKMVSEIRTQQDQILVAKDEVDQRRRFIEAVLSGVTAAVIGVGRDRRITIFNPSS
HHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCC
EGVLRKAAPGLIGARLSDVAPEIEAVLVEAESRYRNDYRKQINIMRGGTERTMNVQVTQE
CCHHHHHCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECC
EGDESHGSYVITIDDITDLVIAQRSTAWADVARRIAHEIKNPLTPIQLSAERLKRRYGKQ
CCCCCCCCEEEEECCHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCC
INQDDRAVFDQCTETIVRQVEDIGRMVDEFSAFARMPKPTKEESDLRAILKDAVFLREMG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHC
NNHIAFIRDFGDEPLEGQFDGRMLGQAFGNLVKNAVESIEAVPAGSSRGAPTVVIRSRRD
CCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCC
DATGRFVVDVVDNGKGLPTENRHRILEPYMTMREKGTGLGLAIVKKIIEDHGGQLELHDA
CCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEEECCC
PSDFDGGAGAMIRVILPPAGETGGEHNLKDKGNFNGG
CCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MVDGMALPLGTEDGVTAAQDRRASFALPGLMLATGALVCATLSLLVLLGLTPVRPERNIV
CCCCCCCCCCCCCCCCHHHHCCCHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEE
IACAGVNGLFVVGLIYLIAREIFRLLRARSKGRAAARLHVRIVALFSIVAITPAILVAIF
EEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASITLDVGLDRWFSLRTQAIVRSSLNVAQAYVLENASYLQGQTVSMANDLERNRQLYSLD
HHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHCCCEEECC
RTGFVELMTRQARGRGMLGAFLVRADGSAILQANISTDRPLPAIPQDALKSTVSGQPTLI
CCHHHHHHHHHHCCCCCCEEEEEECCCCEEEEEECCCCCCCCCCCHHHHHHHCCCCCCCC
PPGVTNLVGAVIPLENIPGTYLYTVRNVDPEVMRSMRLMEENTAEYKTLEAGRTSLQIAF
CCCHHHHHHHHHCCCCCCCCEEEEEECCCHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHH
GVLYIGFALIVLLAAIWTAIAVADRIVRPIRQLIGAADSVASGNLDVVVPVRAVDGDVGN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEECCCCCHH
LSRTFNKMVSEIRTQQDQILVAKDEVDQRRRFIEAVLSGVTAAVIGVGRDRRITIFNPSS
HHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCC
EGVLRKAAPGLIGARLSDVAPEIEAVLVEAESRYRNDYRKQINIMRGGTERTMNVQVTQE
CCHHHHHCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECC
EGDESHGSYVITIDDITDLVIAQRSTAWADVARRIAHEIKNPLTPIQLSAERLKRRYGKQ
CCCCCCCCEEEEECCHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCC
INQDDRAVFDQCTETIVRQVEDIGRMVDEFSAFARMPKPTKEESDLRAILKDAVFLREMG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHC
NNHIAFIRDFGDEPLEGQFDGRMLGQAFGNLVKNAVESIEAVPAGSSRGAPTVVIRSRRD
CCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCC
DATGRFVVDVVDNGKGLPTENRHRILEPYMTMREKGTGLGLAIVKKIIEDHGGQLELHDA
CCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEEECCC
PSDFDGGAGAMIRVILPPAGETGGEHNLKDKGNFNGG
CCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1661370 [H]