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The map label for this gene is dnaJ2 [H]

Identifier: 150395735

GI number: 150395735

Start: 554913

End: 555971

Strand: Direct

Name: dnaJ2 [H]

Synonym: Smed_0511

Alternate gene names: 150395735

Gene position: 554913-555971 (Clockwise)

Preceding gene: 150395734

Following gene: 150395736

Centisome position: 14.67

GC content: 62.61

Gene sequence:

>1059_bases
ATGATAGCAGCCATGCGCGATCCCTATGCAATTCTTGGTGTGCGTCGCAATGCCGGGCAAGAGGAAATCAAGGCGGCCTG
GCGCTCCGTCGCCAGAGCGGTTCATCCCGACCACAATCAGGATGATCCCTCCGCTACCGAGCGCTTCGCCGAAGCGGGCA
GAGCCTATGAGCTATTGCGCGATCCGGTACGCAGAAGCCGTTACGACTGGGTGCGGCGCGAAGCGGAGCTTCGTCGCATG
GAGGCGATGAAGCAGAAAATGCGCGGACAGGAGCCGGACGATGAGCCGGTCGGCGCAGAAACGGCCGAGGAGGCGATCTC
ACGCATCTTCGGCGTCGATCCGCAGGCCGCGGCTGCGAGACCGAGCGCCGCTGCCCGACCCGTGGAAAAGAACGCGCCTT
CAGTGGGTCCGTTCAAGGCCGAGCCTGCTGCAGAAATGAAACAAGAGCAGCCGAAAGCCGATGCGATGGTGCGGCGTTCC
ATCGCGCCGGCGGCAGAGCTTGTCGCGGCGATCGTCCAGCGCATTCGTGGCCGCATTACGAAAACGGCCGATAAGGTGCC
GGATCTCGCCATCGACATCCATGTGAGCATTGAAGATGTGATCGAGCGCGCGCGGGTGCCGGTGGAGCTTCCCGACGGAG
AGCTGATAAAGGTGTCGATTCCGGTCGGAGCGATGGACGGCCAGACGATCCGCCTCAAGGAGCAAGGCTATCGCGTTGCC
GGGATGGCGCGCGGCGATGTGGTGGCAACCCTTCGCATAGGCCAGGACGGGCCGTTCCGAACGCGGGGTCTCGACATCGT
CACGGCATTGCCGCTCGATCTCCAGAACGCGGTCCTTGGCTGCGAAACGACGATCGAGGCGCCCAATGGACCGGTCACGG
TGGCCATACCGGCGTGGTCAGGCTCCGACAAGTCCATCCGTATTGCCGGGAAAGGTTTGCCCGATGCAAGCGGGCAAAGC
GGCGACCTCGTTGTCGAATTACGGCTGGTGCTTCATGAAAAGCCGGACGACAAAGTGATGGATCTCATGCGATCCCAGCG
CAACGGCCTCTATTTGTGA

Upstream 100 bases:

>100_bases
CGCCCGATCATCGTTCGTGAACGGAGAAAGTCCGATCCGGGCTCTCTTCGATTGGTGAGGTGTCAGGCGGGCATCCGGAG
AAGGCCCGCCTAAAAAGAAA

Downstream 100 bases:

>100_bases
AGCTTTTCTGACGAACTGAACCAATATTACGGGGACTAACAGTTCCTGATCTGCCTGCTGCTTGAACCGCTGTGACGCCT
ATGCCATAGGCAATGCTCGA

Product: heat shock protein DnaJ domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 352; Mature: 352

Protein sequence:

>352_residues
MIAAMRDPYAILGVRRNAGQEEIKAAWRSVARAVHPDHNQDDPSATERFAEAGRAYELLRDPVRRSRYDWVRREAELRRM
EAMKQKMRGQEPDDEPVGAETAEEAISRIFGVDPQAAAARPSAAARPVEKNAPSVGPFKAEPAAEMKQEQPKADAMVRRS
IAPAAELVAAIVQRIRGRITKTADKVPDLAIDIHVSIEDVIERARVPVELPDGELIKVSIPVGAMDGQTIRLKEQGYRVA
GMARGDVVATLRIGQDGPFRTRGLDIVTALPLDLQNAVLGCETTIEAPNGPVTVAIPAWSGSDKSIRIAGKGLPDASGQS
GDLVVELRLVLHEKPDDKVMDLMRSQRNGLYL

Sequences:

>Translated_352_residues
MIAAMRDPYAILGVRRNAGQEEIKAAWRSVARAVHPDHNQDDPSATERFAEAGRAYELLRDPVRRSRYDWVRREAELRRM
EAMKQKMRGQEPDDEPVGAETAEEAISRIFGVDPQAAAARPSAAARPVEKNAPSVGPFKAEPAAEMKQEQPKADAMVRRS
IAPAAELVAAIVQRIRGRITKTADKVPDLAIDIHVSIEDVIERARVPVELPDGELIKVSIPVGAMDGQTIRLKEQGYRVA
GMARGDVVATLRIGQDGPFRTRGLDIVTALPLDLQNAVLGCETTIEAPNGPVTVAIPAWSGSDKSIRIAGKGLPDASGQS
GDLVVELRLVLHEKPDDKVMDLMRSQRNGLYL
>Mature_352_residues
MIAAMRDPYAILGVRRNAGQEEIKAAWRSVARAVHPDHNQDDPSATERFAEAGRAYELLRDPVRRSRYDWVRREAELRRM
EAMKQKMRGQEPDDEPVGAETAEEAISRIFGVDPQAAAARPSAAARPVEKNAPSVGPFKAEPAAEMKQEQPKADAMVRRS
IAPAAELVAAIVQRIRGRITKTADKVPDLAIDIHVSIEDVIERARVPVELPDGELIKVSIPVGAMDGQTIRLKEQGYRVA
GMARGDVVATLRIGQDGPFRTRGLDIVTALPLDLQNAVLGCETTIEAPNGPVTVAIPAWSGSDKSIRIAGKGLPDASGQS
GDLVVELRLVLHEKPDDKVMDLMRSQRNGLYL

Specific function: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion. Unfolded proteins bind initially to dnaJ; upon

COG id: COG2214

COG function: function code O; DnaJ-class molecular chaperone

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 J domain [H]

Homologues:

Organism=Homo sapiens, GI205360838, Length=66, Percent_Identity=53.030303030303, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI205360840, Length=66, Percent_Identity=53.030303030303, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI7706495, Length=74, Percent_Identity=47.2972972972973, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI56687498, Length=63, Percent_Identity=47.6190476190476, Blast_Score=66, Evalue=4e-11,
Organism=Escherichia coli, GI1787235, Length=343, Percent_Identity=27.9883381924198, Blast_Score=100, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI212645553, Length=69, Percent_Identity=46.3768115942029, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI115532476, Length=68, Percent_Identity=47.0588235294118, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI19920464, Length=347, Percent_Identity=25.3602305475504, Blast_Score=92, Evalue=6e-19,
Organism=Drosophila melanogaster, GI45552813, Length=380, Percent_Identity=23.4210526315789, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI45549272, Length=380, Percent_Identity=23.4210526315789, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI45552811, Length=71, Percent_Identity=43.6619718309859, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002939
- InterPro:   IPR001623
- InterPro:   IPR008971
- InterPro:   IPR015609
- InterPro:   IPR003095 [H]

Pfam domain/function: PF00226 DnaJ; PF01556 DnaJ_C [H]

EC number: NA

Molecular weight: Translated: 38400; Mature: 38400

Theoretical pI: Translated: 6.56; Mature: 6.56

Prosite motif: PS00636 DNAJ_1 ; PS50076 DNAJ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIAAMRDPYAILGVRRNAGQEEIKAAWRSVARAVHPDHNQDDPSATERFAEAGRAYELLR
CCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
DPVRRSRYDWVRREAELRRMEAMKQKMRGQEPDDEPVGAETAEEAISRIFGVDPQAAAAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHCC
PSAAARPVEKNAPSVGPFKAEPAAEMKQEQPKADAMVRRSIAPAAELVAAIVQRIRGRIT
CCHHCCCCCCCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
KTADKVPDLAIDIHVSIEDVIERARVPVELPDGELIKVSIPVGAMDGQTIRLKEQGYRVA
HHHHCCCCEEEEEEECHHHHHHHHCCCEECCCCCEEEEEECCCCCCCCEEEECCCCCEEE
GMARGDVVATLRIGQDGPFRTRGLDIVTALPLDLQNAVLGCETTIEAPNGPVTVAIPAWS
EECCCCEEEEEEECCCCCCCCCCCEEEEECCCCHHHHHCCCCEEEECCCCCEEEEEECCC
GSDKSIRIAGKGLPDASGQSGDLVVELRLVLHEKPDDKVMDLMRSQRNGLYL
CCCCEEEEEECCCCCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MIAAMRDPYAILGVRRNAGQEEIKAAWRSVARAVHPDHNQDDPSATERFAEAGRAYELLR
CCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
DPVRRSRYDWVRREAELRRMEAMKQKMRGQEPDDEPVGAETAEEAISRIFGVDPQAAAAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHCC
PSAAARPVEKNAPSVGPFKAEPAAEMKQEQPKADAMVRRSIAPAAELVAAIVQRIRGRIT
CCHHCCCCCCCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
KTADKVPDLAIDIHVSIEDVIERARVPVELPDGELIKVSIPVGAMDGQTIRLKEQGYRVA
HHHHCCCCEEEEEEECHHHHHHHHCCCEECCCCCEEEEEECCCCCCCCEEEECCCCCEEE
GMARGDVVATLRIGQDGPFRTRGLDIVTALPLDLQNAVLGCETTIEAPNGPVTVAIPAWS
EECCCCEEEEEEECCCCCCCCCCCEEEEECCCCHHHHHCCCCEEEECCCCCEEEEEECCC
GSDKSIRIAGKGLPDASGQSGDLVVELRLVLHEKPDDKVMDLMRSQRNGLYL
CCCCEEEEEECCCCCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]