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The map label for this gene is divK [H]

Identifier: 150395654

GI number: 150395654

Start: 463541

End: 465280

Strand: Direct

Name: divK [H]

Synonym: Smed_0429

Alternate gene names: 150395654

Gene position: 463541-465280 (Clockwise)

Preceding gene: 150395651

Following gene: 150395655

Centisome position: 12.26

GC content: 62.87

Gene sequence:

>1740_bases
ATGGGTGATGTGGCGTCGGACGGCGCAGACATCAGCAGGAACATTCTGGAGGCAAGCGGCGAAGCGCTTGGCGCCGCCTT
GCTCGTTTTCGACCGGGACGACACCATCATCTTTGCGAGCGCCGCAATAGTGCAATTCTTCCCCGTGCCCGCCGCCATGC
TGCTGCCTGGAACGCAGCTGCGAAGCTTCCTTGGCGCGGTCTACGATACGGGCGTGCGTCCCGGAACCTTGCCGGAGTCC
AGCCGGCACCGGCCGAATCGCGAGGAGTGGATCGCCGAGCAGATGGCGCTTCACTGGCGGGAGCGTTACGAAAACGTCGA
GCGGGCCGGCCGCACACGCTGGCTCTTTCTGCGTCAGCGGCGCCTGTCGAGCGGCATCGGCATTCTCGCCGTCAGCGACG
TCTCGGAACAGAAAAAGCGCGACGAACATTTCCGCGCCGATCTCGAGCGGATCACACTGACACAAGAGATACTCCATGCT
CAGCCCAATCCCATATGCGTCAAAGACCGCAGCCTCAACTACATCGCCGTAAACAGAGCCTTCTGCGCCATTCACGACCT
ATCCCCCGACGCCATGCTTGGACGCTCGGCAGCGGACCTCCTGGGACCTGAGGTTGCGGAGCACTTCGATCGCTCGGATC
GTCACGTCCTCGAGACAGGCACGTCGCACTCTGAAGCTGAGCACATCGTTCGGGCTGACGGCAGCGACCTTTGGGTGGTG
ACGCGCAAATACCGCGTCGGATTGCCAGGCCGCCATTTCCTGGTCACCTGCATGAATGACGTCACCGATATCGCCGTCTG
GTACGACGGCTCGGAAAAGGGCGGAGATACCGGCCTGCAGATCCGTGACTACAGCATCTTCACGCCAGCTCAGAATTTCT
ACGATCCCTTCCGTTCGCCCGCCGTGTCGCAACGCGTCGATCCCGAGCCGAACGACGACGTGCCCCCGGCGCTTGGGGCG
TTGCGCGTGCTTCTGGCGACCGCCGACGTGGAAATGGAGGAGCGCTTCGTGACGCGGCTGCGTGGCTCCGGGCTCGACGC
CTGTGCAGTCCGCAATATCGAGGAGCTCGACGCCTTTGCGGTCGCCGCGGAAGGCCGCGGATTGGAGCTCGACCTTCTAT
TGCTCGACGTCGCGCTTCCGGGGAGGCACCGCGTTCTGACCTCCTGGCGCGCCTGTACCTGGGTCGAGGTGTCGAGCGAT
ATGGATGCGACGGTGCTGCTTGCGGAGATTTTCGGCGTCTGTGCCAATAGCACGCGTTCTGCGCTTCCGAAATCCGAATG
GGGGATGGCGTTCGACAGCGATCCCGTGCCCGCGGCGCAAGTCGCCATGGTGGACGTGCTCGTCGCGGAGGACAACCAGG
TCAACCAGTTCGTATTCGCGCAGATTCTGGAGGGCCTCGGCATCAGCCATCGGATCGCGGCAGACGGAAGAGAAGCAGTG
GACCTTTGGCATGAGCTCCAGCCCGCCCTCGTTCTGATGGACGTGTCCATGCCTGTCATGAACGGCTTCGAGGCTGCTGT
GGCCATACGCGAGGCTGAGAGGCCCGCGGGTCGTCGCACGACCATCGTGGCTGTGACTGCGCAGGCTCTCGATATCGACC
TTGAGCACTGCAGGACATCGGGAATGGACGACCACATCATGAAGCCGATCAGCCCGGACATGATCGAGATGCTGCTCCGG
AAATACCTGCCGGCAGTCGATACATACGCTTCGGGTTCTGTCCGGAGCGGGTCGCGATGA

Upstream 100 bases:

>100_bases
AACCGCTGCTGAGCGAGCTATGAAACCGTTCAGCAGTCAGATTGCTGCAGTACCCGTACGTCCAAGGACGGCTGGCTGTA
GCGGTAACGAGGGCAGCGCG

Downstream 100 bases:

>100_bases
CATTGCGGGAGCTCGGACTCGATCGGCCGAATCGGGAAAAGCCGCGCAGCGCGTCATTCGTCGATCCGTTGACGGGGCTC
GGCAACGCAGTCCACCTTGA

Product: putative PAS/PAC sensor protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 579; Mature: 578

Protein sequence:

>579_residues
MGDVASDGADISRNILEASGEALGAALLVFDRDDTIIFASAAIVQFFPVPAAMLLPGTQLRSFLGAVYDTGVRPGTLPES
SRHRPNREEWIAEQMALHWRERYENVERAGRTRWLFLRQRRLSSGIGILAVSDVSEQKKRDEHFRADLERITLTQEILHA
QPNPICVKDRSLNYIAVNRAFCAIHDLSPDAMLGRSAADLLGPEVAEHFDRSDRHVLETGTSHSEAEHIVRADGSDLWVV
TRKYRVGLPGRHFLVTCMNDVTDIAVWYDGSEKGGDTGLQIRDYSIFTPAQNFYDPFRSPAVSQRVDPEPNDDVPPALGA
LRVLLATADVEMEERFVTRLRGSGLDACAVRNIEELDAFAVAAEGRGLELDLLLLDVALPGRHRVLTSWRACTWVEVSSD
MDATVLLAEIFGVCANSTRSALPKSEWGMAFDSDPVPAAQVAMVDVLVAEDNQVNQFVFAQILEGLGISHRIAADGREAV
DLWHELQPALVLMDVSMPVMNGFEAAVAIREAERPAGRRTTIVAVTAQALDIDLEHCRTSGMDDHIMKPISPDMIEMLLR
KYLPAVDTYASGSVRSGSR

Sequences:

>Translated_579_residues
MGDVASDGADISRNILEASGEALGAALLVFDRDDTIIFASAAIVQFFPVPAAMLLPGTQLRSFLGAVYDTGVRPGTLPES
SRHRPNREEWIAEQMALHWRERYENVERAGRTRWLFLRQRRLSSGIGILAVSDVSEQKKRDEHFRADLERITLTQEILHA
QPNPICVKDRSLNYIAVNRAFCAIHDLSPDAMLGRSAADLLGPEVAEHFDRSDRHVLETGTSHSEAEHIVRADGSDLWVV
TRKYRVGLPGRHFLVTCMNDVTDIAVWYDGSEKGGDTGLQIRDYSIFTPAQNFYDPFRSPAVSQRVDPEPNDDVPPALGA
LRVLLATADVEMEERFVTRLRGSGLDACAVRNIEELDAFAVAAEGRGLELDLLLLDVALPGRHRVLTSWRACTWVEVSSD
MDATVLLAEIFGVCANSTRSALPKSEWGMAFDSDPVPAAQVAMVDVLVAEDNQVNQFVFAQILEGLGISHRIAADGREAV
DLWHELQPALVLMDVSMPVMNGFEAAVAIREAERPAGRRTTIVAVTAQALDIDLEHCRTSGMDDHIMKPISPDMIEMLLR
KYLPAVDTYASGSVRSGSR
>Mature_578_residues
GDVASDGADISRNILEASGEALGAALLVFDRDDTIIFASAAIVQFFPVPAAMLLPGTQLRSFLGAVYDTGVRPGTLPESS
RHRPNREEWIAEQMALHWRERYENVERAGRTRWLFLRQRRLSSGIGILAVSDVSEQKKRDEHFRADLERITLTQEILHAQ
PNPICVKDRSLNYIAVNRAFCAIHDLSPDAMLGRSAADLLGPEVAEHFDRSDRHVLETGTSHSEAEHIVRADGSDLWVVT
RKYRVGLPGRHFLVTCMNDVTDIAVWYDGSEKGGDTGLQIRDYSIFTPAQNFYDPFRSPAVSQRVDPEPNDDVPPALGAL
RVLLATADVEMEERFVTRLRGSGLDACAVRNIEELDAFAVAAEGRGLELDLLLLDVALPGRHRVLTSWRACTWVEVSSDM
DATVLLAEIFGVCANSTRSALPKSEWGMAFDSDPVPAAQVAMVDVLVAEDNQVNQFVFAQILEGLGISHRIAADGREAVD
LWHELQPALVLMDVSMPVMNGFEAAVAIREAERPAGRRTTIVAVTAQALDIDLEHCRTSGMDDHIMKPISPDMIEMLLRK
YLPAVDTYASGSVRSGSR

Specific function: Essential protein that is involved in the control of cell division, probably through the regulation of ctrA. Its phosphorylation status is regulated by PdhS [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm. Note=Localized at one pole of the cell. Colocalizes with pdhS (By similarity) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI145693157, Length=172, Percent_Identity=29.6511627906977, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1789149, Length=162, Percent_Identity=27.7777777777778, Blast_Score=63, Evalue=6e-11,
Organism=Escherichia coli, GI48994928, Length=137, Percent_Identity=32.8467153284672, Blast_Score=63, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6323034, Length=132, Percent_Identity=31.8181818181818, Blast_Score=76, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6322044, Length=128, Percent_Identity=36.71875, Blast_Score=74, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001789 [H]

Pfam domain/function: PF00072 Response_reg [H]

EC number: 2.7.3.- [C]

Molecular weight: Translated: 63845; Mature: 63714

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: PS50112 PAS ; PS50110 RESPONSE_REGULATORY ; PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGDVASDGADISRNILEASGEALGAALLVFDRDDTIIFASAAIVQFFPVPAAMLLPGTQL
CCCCCCCCCHHHHHHHHHCCCCCEEEEEEEECCCCEEEEHHHHHHHHCCCHHHHCCCHHH
RSFLGAVYDTGVRPGTLPESSRHRPNREEWIAEQMALHWRERYENVERAGRTRWLFLRQR
HHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
RLSSGIGILAVSDVSEQKKRDEHFRADLERITLTQEILHAQPNPICVKDRSLNYIAVNRA
HHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEECCE
FCAIHDLSPDAMLGRSAADLLGPEVAEHFDRSDRHVLETGTSHSEAEHIVRADGSDLWVV
EEEEECCCCHHHHCCCHHHHCCHHHHHHCCCCCCCHHHCCCCHHHHHHHHCCCCCCEEEE
TRKYRVGLPGRHFLVTCMNDVTDIAVWYDGSEKGGDTGLQIRDYSIFTPAQNFYDPFRSP
EEEEECCCCCCEEEEEECCCCCEEEEEECCCCCCCCCCCEEEEEEEECCCHHHHHHHCCC
AVSQRVDPEPNDDVPPALGALRVLLATADVEMEERFVTRLRGSGLDACAVRNIEELDAFA
CHHCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHCCHHHHHHEE
VAAEGRGLELDLLLLDVALPGRHRVLTSWRACTWVEVSSDMDATVLLAEIFGVCANSTRS
EEECCCCCEEEEEEEEECCCCCCHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHCCCHHH
ALPKSEWGMAFDSDPVPAAQVAMVDVLVAEDNQVNQFVFAQILEGLGISHRIAADGREAV
CCCCCCCCCCCCCCCCCHHHHHEEEEEEECCCCHHHHHHHHHHHCCCCCEEECCCCHHHH
DLWHELQPALVLMDVSMPVMNGFEAAVAIREAERPAGRRTTIVAVTAQALDIDLEHCRTS
HHHHHCCCEEEEEECCCHHHCCHHHHHHHHHHCCCCCCCEEEEEEEEHHHHCCHHHHHCC
GMDDHIMKPISPDMIEMLLRKYLPAVDTYASGSVRSGSR
CCCHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
GDVASDGADISRNILEASGEALGAALLVFDRDDTIIFASAAIVQFFPVPAAMLLPGTQL
CCCCCCCCHHHHHHHHHCCCCCEEEEEEEECCCCEEEEHHHHHHHHCCCHHHHCCCHHH
RSFLGAVYDTGVRPGTLPESSRHRPNREEWIAEQMALHWRERYENVERAGRTRWLFLRQR
HHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
RLSSGIGILAVSDVSEQKKRDEHFRADLERITLTQEILHAQPNPICVKDRSLNYIAVNRA
HHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEECCE
FCAIHDLSPDAMLGRSAADLLGPEVAEHFDRSDRHVLETGTSHSEAEHIVRADGSDLWVV
EEEEECCCCHHHHCCCHHHHCCHHHHHHCCCCCCCHHHCCCCHHHHHHHHCCCCCCEEEE
TRKYRVGLPGRHFLVTCMNDVTDIAVWYDGSEKGGDTGLQIRDYSIFTPAQNFYDPFRSP
EEEEECCCCCCEEEEEECCCCCEEEEEECCCCCCCCCCCEEEEEEEECCCHHHHHHHCCC
AVSQRVDPEPNDDVPPALGALRVLLATADVEMEERFVTRLRGSGLDACAVRNIEELDAFA
CHHCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHCCHHHHHHEE
VAAEGRGLELDLLLLDVALPGRHRVLTSWRACTWVEVSSDMDATVLLAEIFGVCANSTRS
EEECCCCCEEEEEEEEECCCCCCHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHCCCHHH
ALPKSEWGMAFDSDPVPAAQVAMVDVLVAEDNQVNQFVFAQILEGLGISHRIAADGREAV
CCCCCCCCCCCCCCCCCHHHHHEEEEEEECCCCHHHHHHHHHHHCCCCCEEECCCCHHHH
DLWHELQPALVLMDVSMPVMNGFEAAVAIREAERPAGRRTTIVAVTAQALDIDLEHCRTS
HHHHHCCCEEEEEECCCHHHCCHHHHHHHHHHCCCCCCCEEEEEEEEHHHHCCHHHHHCC
GMDDHIMKPISPDMIEMLLRKYLPAVDTYASGSVRSGSR
CCCHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Phosphotransferases with a nitrogenous group as acceptor [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA