Click here to switch to the map view.

The map label for this gene is yciR [C]

Identifier: 150395655

GI number: 150395655

Start: 465277

End: 466626

Strand: Direct

Name: yciR [C]

Synonym: Smed_0430

Alternate gene names: 150395655

Gene position: 465277-466626 (Clockwise)

Preceding gene: 150395654

Following gene: 150395657

Centisome position: 12.3

GC content: 62.0

Gene sequence:

>1350_bases
ATGACATTGCGGGAGCTCGGACTCGATCGGCCGAATCGGGAAAAGCCGCGCAGCGCGTCATTCGTCGATCCGTTGACGGG
GCTCGGCAACGCAGTCCACCTTGAGCAAACGGTCTTTACCCTCGCGGCGGAACGCGCAAACGATCCTGCCCCTTTTACCA
TCGCCCTTGCCAATCTGGATGGCTTCAAGCCGATCAACGATCTCTTCGGACCCGAGGCGGGCGACCAGATTCTGCGCCAG
GTGGCGCACCGGCTGAAGGTCTGCGTTCCGGAGGGAGCGACGGTGACCCGTACCAAGGATGACGAATTCGCAATCGTTTT
GCCGCTTGTCTTTGAGCGAAGGAGTGCGGAGAAGCGCGGCCAGATGCTCAAGGAAGCGCTCTCCTCGCCCTTCGCGCTTG
GCGACCGGAACGTCCGCCTGTCGGCCTCTTTCGGCTTTGCTGTCTATCCTTTTGCCGGAGACACATTCGACGACTTGGTG
AAGAGCGCCGACACGGCGCTCTACCGCTCGAAACGGCGCGGCCGCGGCCAGATCACTGTCTATTCGCAAGAGATCGCCCA
GGAGATGAAGCACGCGACACAGCTCGAGCAGGCGCTGCGGAACGCGATCATCGCCGGCGGGATCGATGTCCATTTCCAGC
CGATCGTTGACCTGCGCAGCGATCGGCCCTTGGGCTTCGAGGCCTTGGCGCGGTGGTGCGACGCGGACCTCGGCTATGTC
TCGCCCGCGGTATTCGTGCCGTTCGCGGAAGAGCGGGGTTTCATCGACCGACTTGCGGAAACACTTCTGCGCAAGGCGGC
CCGGGCGGCCCTGTCCTGGCCCGAAGAACTCTTTCTGTCTTTCAACCTCTCCTCGGTCCAACTGATGGATCCGACGACGA
GTGCTCGCCTCCTGGCGATCATAGCCCAGGTGGGCCTCGATCCACGTCGCCTCGAACTCGAAATCACCGAGACGGCCGCG
ATGGCGGATGCCGAGATCGCCCAGAGAATCATCACCGAATTCCGGGCGGCTGGCGTGCGCGTGTCGCTCGACGATTTCGG
AACGGGGCAGTCGAGCCTCGGGCGGCTCAGGGACTTTTCGCTCGACAAGGTGAAGATCGACCGTGCGTTCGTTTCCGGGA
TTTCGTCCGACCGGGCTTCAGAACATATCGTCAAAGCAATCGTTTCAATGTGCGAGGGGCTGGAACTCGCCGTCGTCGCC
GAGGGCATCGAGCACGCATCCGAGGCGTTGAAGCTCAAATCCCTCGGCTGCGGCATGGGACAAGGCTATTTCTTCGGCAA
ACCCGCCGATGCGGATGCCACCATGCGTTACTTGTCTGAGTTCTATCGGGATATTGCGGGGGTGCGCTGA

Upstream 100 bases:

>100_bases
TCATGAAGCCGATCAGCCCGGACATGATCGAGATGCTGCTCCGGAAATACCTGCCGGCAGTCGATACATACGCTTCGGGT
TCTGTCCGGAGCGGGTCGCG

Downstream 100 bases:

>100_bases
AGTGCCTCGTGTCCGCTTGCGGCGTCGCTCCCAGAACGATCGCGCAGCCCTTCTTCCAAGAGCCAATCGCGAACGCGGCG
CGCCTGGCTGTTGAGGTCCC

Product: diguanylate cyclase/phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 449; Mature: 448

Protein sequence:

>449_residues
MTLRELGLDRPNREKPRSASFVDPLTGLGNAVHLEQTVFTLAAERANDPAPFTIALANLDGFKPINDLFGPEAGDQILRQ
VAHRLKVCVPEGATVTRTKDDEFAIVLPLVFERRSAEKRGQMLKEALSSPFALGDRNVRLSASFGFAVYPFAGDTFDDLV
KSADTALYRSKRRGRGQITVYSQEIAQEMKHATQLEQALRNAIIAGGIDVHFQPIVDLRSDRPLGFEALARWCDADLGYV
SPAVFVPFAEERGFIDRLAETLLRKAARAALSWPEELFLSFNLSSVQLMDPTTSARLLAIIAQVGLDPRRLELEITETAA
MADAEIAQRIITEFRAAGVRVSLDDFGTGQSSLGRLRDFSLDKVKIDRAFVSGISSDRASEHIVKAIVSMCEGLELAVVA
EGIEHASEALKLKSLGCGMGQGYFFGKPADADATMRYLSEFYRDIAGVR

Sequences:

>Translated_449_residues
MTLRELGLDRPNREKPRSASFVDPLTGLGNAVHLEQTVFTLAAERANDPAPFTIALANLDGFKPINDLFGPEAGDQILRQ
VAHRLKVCVPEGATVTRTKDDEFAIVLPLVFERRSAEKRGQMLKEALSSPFALGDRNVRLSASFGFAVYPFAGDTFDDLV
KSADTALYRSKRRGRGQITVYSQEIAQEMKHATQLEQALRNAIIAGGIDVHFQPIVDLRSDRPLGFEALARWCDADLGYV
SPAVFVPFAEERGFIDRLAETLLRKAARAALSWPEELFLSFNLSSVQLMDPTTSARLLAIIAQVGLDPRRLELEITETAA
MADAEIAQRIITEFRAAGVRVSLDDFGTGQSSLGRLRDFSLDKVKIDRAFVSGISSDRASEHIVKAIVSMCEGLELAVVA
EGIEHASEALKLKSLGCGMGQGYFFGKPADADATMRYLSEFYRDIAGVR
>Mature_448_residues
TLRELGLDRPNREKPRSASFVDPLTGLGNAVHLEQTVFTLAAERANDPAPFTIALANLDGFKPINDLFGPEAGDQILRQV
AHRLKVCVPEGATVTRTKDDEFAIVLPLVFERRSAEKRGQMLKEALSSPFALGDRNVRLSASFGFAVYPFAGDTFDDLVK
SADTALYRSKRRGRGQITVYSQEIAQEMKHATQLEQALRNAIIAGGIDVHFQPIVDLRSDRPLGFEALARWCDADLGYVS
PAVFVPFAEERGFIDRLAETLLRKAARAALSWPEELFLSFNLSSVQLMDPTTSARLLAIIAQVGLDPRRLELEITETAAM
ADAEIAQRIITEFRAAGVRVSLDDFGTGQSSLGRLRDFSLDKVKIDRAFVSGISSDRASEHIVKAIVSMCEGLELAVVAE
GIEHASEALKLKSLGCGMGQGYFFGKPADADATMRYLSEFYRDIAGVR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PAS (PER-ARNT-SIM) domains [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=439, Percent_Identity=32.3462414578588, Blast_Score=219, Evalue=2e-58,
Organism=Escherichia coli, GI87081921, Length=422, Percent_Identity=29.6208530805687, Blast_Score=171, Evalue=9e-44,
Organism=Escherichia coli, GI1787055, Length=397, Percent_Identity=27.7078085642317, Blast_Score=151, Evalue=9e-38,
Organism=Escherichia coli, GI87081743, Length=243, Percent_Identity=34.9794238683128, Blast_Score=145, Evalue=7e-36,
Organism=Escherichia coli, GI226510982, Length=360, Percent_Identity=28.8888888888889, Blast_Score=138, Evalue=6e-34,
Organism=Escherichia coli, GI1790496, Length=249, Percent_Identity=29.3172690763052, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI87081845, Length=239, Percent_Identity=34.3096234309623, Blast_Score=136, Evalue=3e-33,
Organism=Escherichia coli, GI1788502, Length=237, Percent_Identity=30.379746835443, Blast_Score=122, Evalue=7e-29,
Organism=Escherichia coli, GI87081980, Length=223, Percent_Identity=31.390134529148, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1786507, Length=239, Percent_Identity=28.4518828451883, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI87082096, Length=239, Percent_Identity=30.5439330543933, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1788849, Length=267, Percent_Identity=29.5880149812734, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1787410, Length=238, Percent_Identity=28.5714285714286, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1789650, Length=433, Percent_Identity=22.1709006928406, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1788381, Length=405, Percent_Identity=24.6913580246914, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI145693134, Length=173, Percent_Identity=34.6820809248555, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1787802, Length=141, Percent_Identity=31.9148936170213, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI87081977, Length=158, Percent_Identity=31.6455696202532, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI87081881, Length=167, Percent_Identity=28.7425149700599, Blast_Score=63, Evalue=4e-11,
Organism=Escherichia coli, GI87082007, Length=161, Percent_Identity=30.4347826086957, Blast_Score=62, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013656
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF08447 PAS_3; PF08448 PAS_4 [H]

EC number: NA

Molecular weight: Translated: 49257; Mature: 49126

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLRELGLDRPNREKPRSASFVDPLTGLGNAVHLEQTVFTLAAERANDPAPFTIALANLD
CCHHHHCCCCCCCCCCCCCCCCCHHHHCCCCEEHHHHHHHHHHHHCCCCCCEEEEEECCC
GFKPINDLFGPEAGDQILRQVAHRLKVCVPEGATVTRTKDDEFAIVLPLVFERRSAEKRG
CCCCHHHHCCCCCHHHHHHHHHHHHEEECCCCCEEEECCCCCEEEEHHHHHHHHCHHHHH
QMLKEALSSPFALGDRNVRLSASFGFAVYPFAGDTFDDLVKSADTALYRSKRRGRGQITV
HHHHHHHCCCCEECCCCEEEEEECCEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCEEE
YSQEIAQEMKHATQLEQALRNAIIAGGIDVHFQPIVDLRSDRPLGFEALARWCDADLGYV
EHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHCCCCCCCCCHHHHHHHHCCCCCCC
SPAVFVPFAEERGFIDRLAETLLRKAARAALSWPEELFLSFNLSSVQLMDPTTSARLLAI
CCEEEEEEHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHEEECCCEEEEECCCCHHHHHHH
IAQVGLDPRRLELEITETAAMADAEIAQRIITEFRAAGVRVSLDDFGTGQSSLGRLRDFS
HHHHCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCHHHHHHHHCCC
LDKVKIDRAFVSGISSDRASEHIVKAIVSMCEGLELAVVAEGIEHASEALKLKSLGCGMG
CCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHCCCCCC
QGYFFGKPADADATMRYLSEFYRDIAGVR
CCCCCCCCCCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TLRELGLDRPNREKPRSASFVDPLTGLGNAVHLEQTVFTLAAERANDPAPFTIALANLD
CHHHHCCCCCCCCCCCCCCCCCHHHHCCCCEEHHHHHHHHHHHHCCCCCCEEEEEECCC
GFKPINDLFGPEAGDQILRQVAHRLKVCVPEGATVTRTKDDEFAIVLPLVFERRSAEKRG
CCCCHHHHCCCCCHHHHHHHHHHHHEEECCCCCEEEECCCCCEEEEHHHHHHHHCHHHHH
QMLKEALSSPFALGDRNVRLSASFGFAVYPFAGDTFDDLVKSADTALYRSKRRGRGQITV
HHHHHHHCCCCEECCCCEEEEEECCEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCEEE
YSQEIAQEMKHATQLEQALRNAIIAGGIDVHFQPIVDLRSDRPLGFEALARWCDADLGYV
EHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHCCCCCCCCCHHHHHHHHCCCCCCC
SPAVFVPFAEERGFIDRLAETLLRKAARAALSWPEELFLSFNLSSVQLMDPTTSARLLAI
CCEEEEEEHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHEEECCCEEEEECCCCHHHHHHH
IAQVGLDPRRLELEITETAAMADAEIAQRIITEFRAAGVRVSLDDFGTGQSSLGRLRDFS
HHHHCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCHHHHHHHHCCC
LDKVKIDRAFVSGISSDRASEHIVKAIVSMCEGLELAVVAEGIEHASEALKLKSLGCGMG
CCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHCCCCCC
QGYFFGKPADADATMRYLSEFYRDIAGVR
CCCCCCCCCCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]