Click here to switch to the map view.

The map label for this gene is gph [C]

Identifier: 150395650

GI number: 150395650

Start: 458976

End: 459677

Strand: Direct

Name: gph [C]

Synonym: Smed_0425

Alternate gene names: 150395650

Gene position: 458976-459677 (Clockwise)

Preceding gene: 150395649

Following gene: 150395651

Centisome position: 12.14

GC content: 61.4

Gene sequence:

>702_bases
TTGAAGCCGATCGCCGGCATATTGTTCGACAAGGACGGTACCCTTCTCGATTATGTGAAGAGCTGGGTCCCGGTGAACTA
CGAACTGGCGCGGATCGCTGCCAAGGGCGATGAGGATCTCGCACATGTCCTCCTGCGTGCCGGCGGCATGGACCCGGATT
CCGGACATGTCGTTCCCGACAGCCTGCTTGCGGCCGGCAATACGGTGGAGATTGCCACCGGCATGGTCGGCGCCGGCGCG
CCATTTACCGTGGAAGAACTGACGTCGTTGTTCGACGGACTCTTTGCACAATCGGCGCACTATGCTGTGCCCGTGACCGA
CCTGGCGTCCTTTTTTGCCGGGCTGCACGCAAAAGGTTACCGGCTCGGCGTTGCTTCGAGCGACAACGAGCGCTCGATCC
GCGAAACGGCGAAACGCTTCGGTTTCGAGAACTACCTGCACTATATCGCGGGTTACGACAGCGGCTACGGAACAAAGCCG
GAGCCCGGCATGGTGCTCGGATTTTGTGCCGCAACTGGGCTTGCACCCGATGAGGTGGCCGTTGTCGGAGACAACAATCA
CGACATGCATATGGGCCGCAGTGCCGGCGTCGGCATGACGGTTGCCGTTTTGACCGGCACCGGATCGCGCCAGTCGCTCG
CCGCGGCTTCCGACCATTGCCTGGCCGACATCACCGAGTTGGAGACGGTGCTTACCGTGTGA

Upstream 100 bases:

>100_bases
GAAAGGGCTCGAGCCTTATATCAACCCGCTGGTAGTGAAGGCGCGGCTGGAGCCGCGCCCAAAGCCCGAAGCCTGATTTC
CGGAAGGGACCATGCCCGTA

Downstream 100 bases:

>100_bases
TCGGCTTGCGTTTTTCTCCATTCTGACGTTCTTTGTCGCCGGTATACCGCTAACGGCCGATGCTCGCGGCGGAAGTTCTG
GATATTGCTTCTTCTGCCCA

Product: HAD family hydrolase

Products: glycolate; phosphate

Alternate protein names: Phosphoglycolate Phosphatase; Phosphatase; Haloacid Dehalogenase-Like Hydrolase; HAD Superfamily Hydrolase; Haloacid Dehalogenase/Epoxide Hydrolase Family Protein; Hydrolase; Hydrolase Haloacid Dehalogenase-Like Family; HAD-Superfamily Hydrolase; Haloacid Dehalogenase Domain Protein Hydrolase; HAD-Like Hydrolase; Phosphoglycolate Phosphatase Protein

Number of amino acids: Translated: 233; Mature: 233

Protein sequence:

>233_residues
MKPIAGILFDKDGTLLDYVKSWVPVNYELARIAAKGDEDLAHVLLRAGGMDPDSGHVVPDSLLAAGNTVEIATGMVGAGA
PFTVEELTSLFDGLFAQSAHYAVPVTDLASFFAGLHAKGYRLGVASSDNERSIRETAKRFGFENYLHYIAGYDSGYGTKP
EPGMVLGFCAATGLAPDEVAVVGDNNHDMHMGRSAGVGMTVAVLTGTGSRQSLAAASDHCLADITELETVLTV

Sequences:

>Translated_233_residues
MKPIAGILFDKDGTLLDYVKSWVPVNYELARIAAKGDEDLAHVLLRAGGMDPDSGHVVPDSLLAAGNTVEIATGMVGAGA
PFTVEELTSLFDGLFAQSAHYAVPVTDLASFFAGLHAKGYRLGVASSDNERSIRETAKRFGFENYLHYIAGYDSGYGTKP
EPGMVLGFCAATGLAPDEVAVVGDNNHDMHMGRSAGVGMTVAVLTGTGSRQSLAAASDHCLADITELETVLTV
>Mature_233_residues
MKPIAGILFDKDGTLLDYVKSWVPVNYELARIAAKGDEDLAHVLLRAGGMDPDSGHVVPDSLLAAGNTVEIATGMVGAGA
PFTVEELTSLFDGLFAQSAHYAVPVTDLASFFAGLHAKGYRLGVASSDNERSIRETAKRFGFENYLHYIAGYDSGYGTKP
EPGMVLGFCAATGLAPDEVAVVGDNNHDMHMGRSAGVGMTVAVLTGTGSRQSLAAASDHCLADITELETVLTV

Specific function: Unknown

COG id: COG0546

COG function: function code R; Predicted phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Caenorhabditis elegans, GI71983424, Length=236, Percent_Identity=29.2372881355932, Blast_Score=103, Evalue=7e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.1.3.18

Molecular weight: Translated: 24409; Mature: 24409

Theoretical pI: Translated: 4.57; Mature: 4.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPIAGILFDKDGTLLDYVKSWVPVNYELARIAAKGDEDLAHVLLRAGGMDPDSGHVVPD
CCCCCCEEECCCCCHHHHHHHHCCCCHHEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCH
SLLAAGNTVEIATGMVGAGAPFTVEELTSLFDGLFAQSAHYAVPVTDLASFFAGLHAKGY
HHHHCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCEECHHHHHHHHHHHCCCCE
RLGVASSDNERSIRETAKRFGFENYLHYIAGYDSGYGTKPEPGMVLGFCAATGLAPDEVA
EEEECCCCCHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCEEEEEEHHCCCCCCCEE
VVGDNNHDMHMGRSAGVGMTVAVLTGTGSRQSLAAASDHCLADITELETVLTV
EEECCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKPIAGILFDKDGTLLDYVKSWVPVNYELARIAAKGDEDLAHVLLRAGGMDPDSGHVVPD
CCCCCCEEECCCCCHHHHHHHHCCCCHHEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCH
SLLAAGNTVEIATGMVGAGAPFTVEELTSLFDGLFAQSAHYAVPVTDLASFFAGLHAKGY
HHHHCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCEECHHHHHHHHHHHCCCCE
RLGVASSDNERSIRETAKRFGFENYLHYIAGYDSGYGTKPEPGMVLGFCAATGLAPDEVA
EEEECCCCCHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCEEEEEEHHCCCCCCCEE
VVGDNNHDMHMGRSAGVGMTVAVLTGTGSRQSLAAASDHCLADITELETVLTV
EEECCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Mg2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): 0.57 {phosphoglycolate}} [C]

Substrates: 2-phosphoglycolate; H2O

Specific reaction: 2-phosphoglycolate + H2O = glycolate + phosphate

General reaction: Additional information:

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA