Click here to switch to the map view.

The map label for this gene is exoB [H]

Identifier: 150395395

GI number: 150395395

Start: 185971

End: 186999

Strand: Direct

Name: exoB [H]

Synonym: Smed_0168

Alternate gene names: 150395395

Gene position: 185971-186999 (Clockwise)

Preceding gene: 150395394

Following gene: 150395404

Centisome position: 4.92

GC content: 63.95

Gene sequence:

>1029_bases
ATGGCCGTATTGGTGACGGGCGGGGCAGGCTATATCGGCAGCCACATGGTGTGGTCGCTCCTGGACGCCGGCGAAGCGGT
GGTGGTGCTCGACTGTCTGTCGACCGGCTTCCGGTGGGCGGTCGCGCCGGAGCCGCGCTTCTATCTCGGCGACGCCGGTG
ACCGGGCACTGCTCCAGCGGGTCTTTGCAGAGAACGACATCGACTCCGTGGTTCATTTCGCCGGATCGGCCGTCGTACCG
GAATCGGTCGCCAATCCGCTTGCCTATTACGAGAACAACACGGCCAATACCCGCACGCTTGTTGCCGCAACCATCGAGGC
CGGCATTCGCCACTTCGTCTTTTCATCGACGGCTGCCGTTTACGGGACGCAGGATACGCCCGATCCGGTCAGCGAGACGG
CCGCTCCGCGGCCCCAGAGTCCTTATGGCCGATCCAAGTGGATGTCGGAGTTGATGCTGGCGGATGCGGCGGCCGCGCAT
GATTTCCGTTTTGTCGCGTTGCGCTATTTCAATGTGGCCGGCGCGGATCCGCTTGGTCGCGCCGGTCAGTCGACGTTCGG
CGCCACGCATCTGATCAAGGTCGCCTGCGAAGCGGCGCTCGGCAAACGTCACAAGGTCGATGTCTTCGGCATCGACTATC
CGACGGCGGACGGCACCGGTGTTCGAGACTATATCCATGTGAGTGACCTTGTCGCGGCGCACCGGAGCGCGCTCGCCTAT
CTGCGGATGGGCGGCGAACCGCTCGTCACAAATTGCGGCTACGGCCACGGCTTTTCGGTGCTGCAGGTGCTCGATACGGT
ACGGCAGGTTTCCGGCCGCGACTTCACGGTCGACTATGCGCCACGGCGCCCGGGTGATCCGGCGCAAGTGGTCGCCGATC
CCTCCGTAGCGCGTCTGAAACTCGACTGGGTTCCGACGCATGCGAGCCTGGAACATATCGTCCAGAGCGCCTACGACTGG
GAGGGCTATCTCAGCCGTAAGAACAGCTTCGACCGGGAAGGGGACGAGCGGTTGATCGCCAGAGGCTGA

Upstream 100 bases:

>100_bases
AATAGGCGCTCGGGCGGGCGAAACGGCCCCTGTATTTACCATTTCTGAAACGAGCACTCGTCATTTCTGATCCTGCGTAG
GAAGCGACTGGGGGCGGGAA

Downstream 100 bases:

>100_bases
CACTCGATAACGTCTTAAGCTTCAAATTTCAGCGTCGTCCTCGCCGAGAAGCTTGCGCTCATGGGCGATGGCACTTTCGA
CAAGTCGCGCCCACAGATCC

Product: UDP-glucose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 342; Mature: 341

Protein sequence:

>342_residues
MAVLVTGGAGYIGSHMVWSLLDAGEAVVVLDCLSTGFRWAVAPEPRFYLGDAGDRALLQRVFAENDIDSVVHFAGSAVVP
ESVANPLAYYENNTANTRTLVAATIEAGIRHFVFSSTAAVYGTQDTPDPVSETAAPRPQSPYGRSKWMSELMLADAAAAH
DFRFVALRYFNVAGADPLGRAGQSTFGATHLIKVACEAALGKRHKVDVFGIDYPTADGTGVRDYIHVSDLVAAHRSALAY
LRMGGEPLVTNCGYGHGFSVLQVLDTVRQVSGRDFTVDYAPRRPGDPAQVVADPSVARLKLDWVPTHASLEHIVQSAYDW
EGYLSRKNSFDREGDERLIARG

Sequences:

>Translated_342_residues
MAVLVTGGAGYIGSHMVWSLLDAGEAVVVLDCLSTGFRWAVAPEPRFYLGDAGDRALLQRVFAENDIDSVVHFAGSAVVP
ESVANPLAYYENNTANTRTLVAATIEAGIRHFVFSSTAAVYGTQDTPDPVSETAAPRPQSPYGRSKWMSELMLADAAAAH
DFRFVALRYFNVAGADPLGRAGQSTFGATHLIKVACEAALGKRHKVDVFGIDYPTADGTGVRDYIHVSDLVAAHRSALAY
LRMGGEPLVTNCGYGHGFSVLQVLDTVRQVSGRDFTVDYAPRRPGDPAQVVADPSVARLKLDWVPTHASLEHIVQSAYDW
EGYLSRKNSFDREGDERLIARG
>Mature_341_residues
AVLVTGGAGYIGSHMVWSLLDAGEAVVVLDCLSTGFRWAVAPEPRFYLGDAGDRALLQRVFAENDIDSVVHFAGSAVVPE
SVANPLAYYENNTANTRTLVAATIEAGIRHFVFSSTAAVYGTQDTPDPVSETAAPRPQSPYGRSKWMSELMLADAAAAHD
FRFVALRYFNVAGADPLGRAGQSTFGATHLIKVACEAALGKRHKVDVFGIDYPTADGTGVRDYIHVSDLVAAHRSALAYL
RMGGEPLVTNCGYGHGFSVLQVLDTVRQVSGRDFTVDYAPRRPGDPAQVVADPSVARLKLDWVPTHASLEHIVQSAYDWE
GYLSRKNSFDREGDERLIARG

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=336, Percent_Identity=38.9880952380952, Blast_Score=199, Evalue=2e-51,
Organism=Homo sapiens, GI56118217, Length=336, Percent_Identity=38.9880952380952, Blast_Score=199, Evalue=2e-51,
Organism=Homo sapiens, GI189083684, Length=336, Percent_Identity=38.9880952380952, Blast_Score=199, Evalue=2e-51,
Organism=Homo sapiens, GI7657641, Length=299, Percent_Identity=27.0903010033445, Blast_Score=87, Evalue=3e-17,
Organism=Escherichia coli, GI1786974, Length=331, Percent_Identity=41.0876132930514, Blast_Score=228, Evalue=6e-61,
Organism=Escherichia coli, GI48994969, Length=380, Percent_Identity=28.4210526315789, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1788353, Length=377, Percent_Identity=25.9946949602122, Blast_Score=73, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI71982035, Length=340, Percent_Identity=36.4705882352941, Blast_Score=209, Evalue=2e-54,
Organism=Caenorhabditis elegans, GI71982038, Length=342, Percent_Identity=36.2573099415205, Blast_Score=208, Evalue=3e-54,
Organism=Caenorhabditis elegans, GI17568069, Length=248, Percent_Identity=27.4193548387097, Blast_Score=79, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6319493, Length=335, Percent_Identity=38.8059701492537, Blast_Score=198, Evalue=1e-51,
Organism=Drosophila melanogaster, GI19923002, Length=337, Percent_Identity=37.9821958456973, Blast_Score=202, Evalue=4e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 36919; Mature: 36788

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVLVTGGAGYIGSHMVWSLLDAGEAVVVLDCLSTGFRWAVAPEPRFYLGDAGDRALLQR
CEEEEECCCCHHHHHHHHHHHCCCCEEEEEEEHHCCCEEEECCCCCEEECCCCCHHHHHH
VFAENDIDSVVHFAGSAVVPESVANPLAYYENNTANTRTLVAATIEAGIRHFVFSSTAAV
HHHCCCHHHHHHHCCCCCCCHHHHCCHHHHCCCCCCCCEEEHHHHHHHHHHHHHHCCEEE
YGTQDTPDPVSETAAPRPQSPYGRSKWMSELMLADAAAAHDFRFVALRYFNVAGADPLGR
ECCCCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCCC
AGQSTFGATHLIKVACEAALGKRHKVDVFGIDYPTADGTGVRDYIHVSDLVAAHRSALAY
CCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
LRMGGEPLVTNCGYGHGFSVLQVLDTVRQVSGRDFTVDYAPRRPGDPAQVVADPSVARLK
HHCCCCCEEECCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHEEECCCEEEEE
LDWVPTHASLEHIVQSAYDWEGYLSRKNSFDREGDERLIARG
EEEECCHHHHHHHHHHHCCHHHHHHCCCCCCCCCCCHHCCCC
>Mature Secondary Structure 
AVLVTGGAGYIGSHMVWSLLDAGEAVVVLDCLSTGFRWAVAPEPRFYLGDAGDRALLQR
EEEEECCCCHHHHHHHHHHHCCCCEEEEEEEHHCCCEEEECCCCCEEECCCCCHHHHHH
VFAENDIDSVVHFAGSAVVPESVANPLAYYENNTANTRTLVAATIEAGIRHFVFSSTAAV
HHHCCCHHHHHHHCCCCCCCHHHHCCHHHHCCCCCCCCEEEHHHHHHHHHHHHHHCCEEE
YGTQDTPDPVSETAAPRPQSPYGRSKWMSELMLADAAAAHDFRFVALRYFNVAGADPLGR
ECCCCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCCC
AGQSTFGATHLIKVACEAALGKRHKVDVFGIDYPTADGTGVRDYIHVSDLVAAHRSALAY
CCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
LRMGGEPLVTNCGYGHGFSVLQVLDTVRQVSGRDFTVDYAPRRPGDPAQVVADPSVARLK
HHCCCCCEEECCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHEEECCCEEEEE
LDWVPTHASLEHIVQSAYDWEGYLSRKNSFDREGDERLIARG
EEEECCHHHHHHHHHHHCCHHHHHHCCCCCCCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8026752 [H]