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The map label for this gene is aspC [H]

Identifier: 150395394

GI number: 150395394

Start: 184634

End: 185800

Strand: Direct

Name: aspC [H]

Synonym: Smed_0167

Alternate gene names: 150395394

Gene position: 184634-185800 (Clockwise)

Preceding gene: 150395393

Following gene: 150395395

Centisome position: 4.88

GC content: 64.7

Gene sequence:

>1167_bases
ATGACGATCACGACGAGCCTCAGTCCACGCGCCACGGCAGCGCCCGAAAGCGGCATCGTCGAAGTGGTCAATTATGCGCG
CGGGCGTGAAGGGCTCATTCCGCTCTGGGTCGGCGAGGGCGATCTGCCGACGCCGGATTTCGTCAGCCGCGCGGCGGCCG
ACGCATTGATGGGTGGCGAAACCTTCTATACCTGGCAGCGCGGCATCCCTCCCTTGCGCGAAGCGCTGGCGCGCTATTAT
CAGCGCCGGTTCCAGAAGACGCTTTCTCCCGAAAACTTCTATGTCACCGGCTCGGGAATGCAGGCCATCAAGCTTGCGAT
CGAGTCGGTCGCATCTCCCGGCGACGAGATGGTCCTGCTCACTCCGGCCTGGCCGAATTTCGCGGCCGCCGCGGATCTTT
CCGGCGTCCGCCCGGTCGCAGTGCCGCTCCGCTTCGAAGCCGGCAAATGGCAGCTCGACCTGACCCGCCTCGAGGCGGCT
ATCGGCGAGAGGACGCGTGCGCTTTTCATCAATACGCCGTCTAACCCGACCGGCTGGACCGCTACGCTTGATGATCTCAA
GTCCATCCTGGCGCTGGCGCGCAAGCACGGCCTTTGGATCGTCGCCGACGAAATCTACGCCCTCTATCATTACCTCGGCG
GCCGGGCGCCGTCGTTCCTCGACGTGATGGAAGAGGAAGATCGCATCCTGTTCGTCAATTCCTTCTCCAAGAACTGGTCG
ATGACCGGCTGGCGCGTCGGCTGGATCGTGGCTCCGCCGGCGATGGGACAGGTGCTTGAGAACCTGATCCAGTATTCGAC
GTCCGGCGTCGCCCAGTTCATGCAGCGCGGCGCCGCAGTGGCACTCGAGGAGGGCGACGGCTTCGTTGACGCGAACATCG
CCAAGGCGAAGCGCAACCGCGATACGCTCTGCGACGCGCTGATCGCGACCAATCGGGTCGAAACCCTGAAACCCGACGGT
GCGCTTTACGCCTTTCTGAAGATCGACGGCGTCGCGGATTCGCGCGCCGCCGCGATCGACATCGTCGATCGGACCGGCGT
GGGGCTGGCGCCCGGAACGGCTTTCGGCGAGGGCGGCGCGCTCTTCATGCGCGCCTGTTTCCTGCGCGATCCTGACCAGA
TCGCCGAGGCCGCGGAGCGATTGCAGCGTTATATCCTCAGCCGCTGA

Upstream 100 bases:

>100_bases
GCCGCGCGAAACATCACGGAAATCGATAAACAGGTCAGAGAAATTCGCGTGATCGGCGACGCCGAAGCGTTTAAAAGCGG
CAGGCAATCAGGAGGCTGCG

Downstream 100 bases:

>100_bases
AGAAGCGCGATTCGACCGATCGCTAAAGCTTGAACGATCCGAGCGAAGGACGCTTAACCACACGGCCGAGAATAGGCGCT
CGGGCGGGCGAAACGGCCCC

Product: aspartate aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 388; Mature: 387

Protein sequence:

>388_residues
MTITTSLSPRATAAPESGIVEVVNYARGREGLIPLWVGEGDLPTPDFVSRAAADALMGGETFYTWQRGIPPLREALARYY
QRRFQKTLSPENFYVTGSGMQAIKLAIESVASPGDEMVLLTPAWPNFAAAADLSGVRPVAVPLRFEAGKWQLDLTRLEAA
IGERTRALFINTPSNPTGWTATLDDLKSILALARKHGLWIVADEIYALYHYLGGRAPSFLDVMEEEDRILFVNSFSKNWS
MTGWRVGWIVAPPAMGQVLENLIQYSTSGVAQFMQRGAAVALEEGDGFVDANIAKAKRNRDTLCDALIATNRVETLKPDG
ALYAFLKIDGVADSRAAAIDIVDRTGVGLAPGTAFGEGGALFMRACFLRDPDQIAEAAERLQRYILSR

Sequences:

>Translated_388_residues
MTITTSLSPRATAAPESGIVEVVNYARGREGLIPLWVGEGDLPTPDFVSRAAADALMGGETFYTWQRGIPPLREALARYY
QRRFQKTLSPENFYVTGSGMQAIKLAIESVASPGDEMVLLTPAWPNFAAAADLSGVRPVAVPLRFEAGKWQLDLTRLEAA
IGERTRALFINTPSNPTGWTATLDDLKSILALARKHGLWIVADEIYALYHYLGGRAPSFLDVMEEEDRILFVNSFSKNWS
MTGWRVGWIVAPPAMGQVLENLIQYSTSGVAQFMQRGAAVALEEGDGFVDANIAKAKRNRDTLCDALIATNRVETLKPDG
ALYAFLKIDGVADSRAAAIDIVDRTGVGLAPGTAFGEGGALFMRACFLRDPDQIAEAAERLQRYILSR
>Mature_387_residues
TITTSLSPRATAAPESGIVEVVNYARGREGLIPLWVGEGDLPTPDFVSRAAADALMGGETFYTWQRGIPPLREALARYYQ
RRFQKTLSPENFYVTGSGMQAIKLAIESVASPGDEMVLLTPAWPNFAAAADLSGVRPVAVPLRFEAGKWQLDLTRLEAAI
GERTRALFINTPSNPTGWTATLDDLKSILALARKHGLWIVADEIYALYHYLGGRAPSFLDVMEEEDRILFVNSFSKNWSM
TGWRVGWIVAPPAMGQVLENLIQYSTSGVAQFMQRGAAVALEEGDGFVDANIAKAKRNRDTLCDALIATNRVETLKPDGA
LYAFLKIDGVADSRAAAIDIVDRTGVGLAPGTAFGEGGALFMRACFLRDPDQIAEAAERLQRYILSR

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=406, Percent_Identity=25.3694581280788, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI169881279, Length=406, Percent_Identity=25.3694581280788, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI56713256, Length=390, Percent_Identity=23.8461538461538, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI56713254, Length=390, Percent_Identity=23.8461538461538, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI4507369, Length=371, Percent_Identity=26.6846361185984, Blast_Score=109, Evalue=3e-24,
Organism=Homo sapiens, GI169881281, Length=306, Percent_Identity=23.202614379085, Blast_Score=89, Evalue=8e-18,
Organism=Homo sapiens, GI7705897, Length=407, Percent_Identity=25.0614250614251, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI33469970, Length=407, Percent_Identity=25.0614250614251, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI4885351, Length=389, Percent_Identity=25.1928020565553, Blast_Score=80, Evalue=3e-15,
Organism=Escherichia coli, GI1788722, Length=362, Percent_Identity=28.4530386740331, Blast_Score=125, Evalue=5e-30,
Organism=Escherichia coli, GI1786816, Length=358, Percent_Identity=26.536312849162, Blast_Score=116, Evalue=3e-27,
Organism=Escherichia coli, GI1788627, Length=342, Percent_Identity=28.3625730994152, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1787710, Length=190, Percent_Identity=28.4210526315789, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787909, Length=181, Percent_Identity=24.3093922651934, Blast_Score=65, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI71994472, Length=240, Percent_Identity=27.5, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI71994476, Length=240, Percent_Identity=27.5, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17567369, Length=385, Percent_Identity=22.0779220779221, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17567663, Length=325, Percent_Identity=24.9230769230769, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI71981209, Length=365, Percent_Identity=22.4657534246575, Blast_Score=75, Evalue=6e-14,
Organism=Saccharomyces cerevisiae, GI6322401, Length=239, Percent_Identity=28.8702928870293, Blast_Score=100, Evalue=4e-22,
Organism=Drosophila melanogaster, GI28573069, Length=388, Percent_Identity=23.9690721649485, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24646114, Length=388, Percent_Identity=23.9690721649485, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI28573067, Length=388, Percent_Identity=23.9690721649485, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI28573065, Length=388, Percent_Identity=23.9690721649485, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI18859735, Length=377, Percent_Identity=23.342175066313, Blast_Score=88, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 42321; Mature: 42190

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTITTSLSPRATAAPESGIVEVVNYARGREGLIPLWVGEGDLPTPDFVSRAAADALMGGE
CEEECCCCCCCCCCCCCCHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCC
TFYTWQRGIPPLREALARYYQRRFQKTLSPENFYVTGSGMQAIKLAIESVASPGDEMVLL
EEEEHHCCCCHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHCCCCCCEEEE
TPAWPNFAAAADLSGVRPVAVPLRFEAGKWQLDLTRLEAAIGERTRALFINTPSNPTGWT
ECCCCCCHHHHCCCCCCEEEEEEEEECCCEEEHHHHHHHHHCCCCEEEEEECCCCCCCCE
ATLDDLKSILALARKHGLWIVADEIYALYHYLGGRAPSFLDVMEEEDRILFVNSFSKNWS
EEHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHCCCCCHHHHHHCCCCCEEEEEECCCCCC
MTGWRVGWIVAPPAMGQVLENLIQYSTSGVAQFMQRGAAVALEEGDGFVDANIAKAKRNR
CCCEEEEEEECCHHHHHHHHHHHHHCCHHHHHHHHCCCEEEEECCCCEEECHHHHHHCCH
DTLCDALIATNRVETLKPDGALYAFLKIDGVADSRAAAIDIVDRTGVGLAPGTAFGEGGA
HHHHHHHHHCCCHHEECCCCCEEEEEEEECCCCCCCEEEEEEECCCCCCCCCCCCCCCCH
LFMRACFLRDPDQIAEAAERLQRYILSR
HHHHHHHCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TITTSLSPRATAAPESGIVEVVNYARGREGLIPLWVGEGDLPTPDFVSRAAADALMGGE
EEECCCCCCCCCCCCCCHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCC
TFYTWQRGIPPLREALARYYQRRFQKTLSPENFYVTGSGMQAIKLAIESVASPGDEMVLL
EEEEHHCCCCHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHCCCCCCEEEE
TPAWPNFAAAADLSGVRPVAVPLRFEAGKWQLDLTRLEAAIGERTRALFINTPSNPTGWT
ECCCCCCHHHHCCCCCCEEEEEEEEECCCEEEHHHHHHHHHCCCCEEEEEECCCCCCCCE
ATLDDLKSILALARKHGLWIVADEIYALYHYLGGRAPSFLDVMEEEDRILFVNSFSKNWS
EEHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHCCCCCHHHHHHCCCCCEEEEEECCCCCC
MTGWRVGWIVAPPAMGQVLENLIQYSTSGVAQFMQRGAAVALEEGDGFVDANIAKAKRNR
CCCEEEEEEECCHHHHHHHHHHHHHCCHHHHHHHHCCCEEEEECCCCEEECHHHHHHCCH
DTLCDALIATNRVETLKPDGALYAFLKIDGVADSRAAAIDIVDRTGVGLAPGTAFGEGGA
HHHHHHHHHCCCHHEECCCCCEEEEEEEECCCCCCCEEEEEEECCCCCCCCCCCCCCCCH
LFMRACFLRDPDQIAEAAERLQRYILSR
HHHHHHHCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]