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The map label for this gene is trpS [H]

Identifier: 150395262

GI number: 150395262

Start: 36212

End: 37276

Strand: Direct

Name: trpS [H]

Synonym: Smed_0034

Alternate gene names: 150395262

Gene position: 36212-37276 (Clockwise)

Preceding gene: 150395261

Following gene: 150395263

Centisome position: 0.96

GC content: 61.97

Gene sequence:

>1065_bases
ATGACCGAATTCAAGCCGCTCGTATTTTCCGGCGTTCAACCGACCGGCAACCTGCATCTCGGCAATTATCTGGGCGCGAT
CCGGAAATTCGTCGCCCTTCAGGACAACAACGACTGCATCTACTGCGTCGTCGATCTCCACTCGATCACGGCGCAGCTCG
TGCATGAGGACCTGCGGGGCCAGATCCGGTCGATCGCAGCCGCCTTCATCGCATCGGGCATCGATCCCGAAAAGCACATC
GTCTTCAACCAGTCGGCCGTGCCGCAGCACGCCGAGCTCGCCTGGATCTTCAACTGCGTCGCCCGCATCGGCTGGATGAA
CCGGATGACACAGTTCAAGGACAAGGCCGGCAAGGACCGGGAAAACGCCTCGCTCGGCCTCCTTGCCTATCCGAGTCTCA
TGGCAGCCGATATCCTCGTCTATCGCGCCACCCACGTGCCTGTCGGCGACGACCAGAAGCAGCATCTGGAGCTTACCCGC
GACATCGCCCAGAAGTTCAACATCGACTTCATGGCGCATATCCGGGCGCGCGGCTACGGCGTCGACATCGTCGTCGGCGA
AGAGCCGATCCATGCCTATTTCCCGCCGGTCGAGCCGCTGATCGGCGGTCCGGCGCCGCGCGTCATGTCACTACGCGACG
GCACCAAGAAGATGTCGAAATCCGATCCATCCGATTTGTCGCGCATCAACCTGATGGACGATGCCGACACGATCCTGAAG
AAGATCCGCAAAGCCAAGACCGATCCGGACGCGCTGCCGAGCGAGGCGGACGGTCTCAAGGGGCGGCCGGAGGCCGAAAA
TCTCGTCGGTATCTACGCGGCGCTATCCGACAGGTCGAAGGACGAGGTGCTTGCCGAGTTCGGCGGGCAGCAATTCTCGG
CTTTCAAACCGGCCCTGGCCGATCTGGCCGTGACCGTACTTTCGCCGATCACGGGCGAGATGCGCCGATTGATGGGCGAT
ACCGCGCATATCGACGCTATCCTGCGCAAGGGCGGCGAGCGGGCCAGGGAGCGCGCCGAAAAAACAATGCGGGAGGTCCG
CGAGATCATCGGCTTTTTGCAGTAG

Upstream 100 bases:

>100_bases
GCCGGCGTGACCCGCCTCTTGATTGCGCCCGTGCTGCCGTGCATAAGCGCGGCGGATATCAACTGGAGACGGGCCCTCCA
CAAGCCCGATTGAGGACGAC

Downstream 100 bases:

>100_bases
TTGGTGAAAATGAGACCTTGCGGGCGCCGCGCGGCGTTGTAATGTTCGGCGCATGGTTTCAACGCGACTCTCACGACTGG
AAGGTCATCGCCGCAAGTTC

Product: tryptophanyl-tRNA synthetase

Products: NA

Alternate protein names: Tryptophan--tRNA ligase; TrpRS [H]

Number of amino acids: Translated: 354; Mature: 353

Protein sequence:

>354_residues
MTEFKPLVFSGVQPTGNLHLGNYLGAIRKFVALQDNNDCIYCVVDLHSITAQLVHEDLRGQIRSIAAAFIASGIDPEKHI
VFNQSAVPQHAELAWIFNCVARIGWMNRMTQFKDKAGKDRENASLGLLAYPSLMAADILVYRATHVPVGDDQKQHLELTR
DIAQKFNIDFMAHIRARGYGVDIVVGEEPIHAYFPPVEPLIGGPAPRVMSLRDGTKKMSKSDPSDLSRINLMDDADTILK
KIRKAKTDPDALPSEADGLKGRPEAENLVGIYAALSDRSKDEVLAEFGGQQFSAFKPALADLAVTVLSPITGEMRRLMGD
TAHIDAILRKGGERARERAEKTMREVREIIGFLQ

Sequences:

>Translated_354_residues
MTEFKPLVFSGVQPTGNLHLGNYLGAIRKFVALQDNNDCIYCVVDLHSITAQLVHEDLRGQIRSIAAAFIASGIDPEKHI
VFNQSAVPQHAELAWIFNCVARIGWMNRMTQFKDKAGKDRENASLGLLAYPSLMAADILVYRATHVPVGDDQKQHLELTR
DIAQKFNIDFMAHIRARGYGVDIVVGEEPIHAYFPPVEPLIGGPAPRVMSLRDGTKKMSKSDPSDLSRINLMDDADTILK
KIRKAKTDPDALPSEADGLKGRPEAENLVGIYAALSDRSKDEVLAEFGGQQFSAFKPALADLAVTVLSPITGEMRRLMGD
TAHIDAILRKGGERARERAEKTMREVREIIGFLQ
>Mature_353_residues
TEFKPLVFSGVQPTGNLHLGNYLGAIRKFVALQDNNDCIYCVVDLHSITAQLVHEDLRGQIRSIAAAFIASGIDPEKHIV
FNQSAVPQHAELAWIFNCVARIGWMNRMTQFKDKAGKDRENASLGLLAYPSLMAADILVYRATHVPVGDDQKQHLELTRD
IAQKFNIDFMAHIRARGYGVDIVVGEEPIHAYFPPVEPLIGGPAPRVMSLRDGTKKMSKSDPSDLSRINLMDDADTILKK
IRKAKTDPDALPSEADGLKGRPEAENLVGIYAALSDRSKDEVLAEFGGQQFSAFKPALADLAVTVLSPITGEMRRLMGDT
AHIDAILRKGGERARERAEKTMREVREIIGFLQ

Specific function: Unknown

COG id: COG0180

COG function: function code J; Tryptophanyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI7710154, Length=351, Percent_Identity=41.025641025641, Blast_Score=263, Evalue=1e-70,
Organism=Homo sapiens, GI41352700, Length=167, Percent_Identity=51.497005988024, Blast_Score=181, Evalue=8e-46,
Organism=Escherichia coli, GI1789786, Length=349, Percent_Identity=41.8338108882521, Blast_Score=281, Evalue=6e-77,
Organism=Caenorhabditis elegans, GI71982800, Length=353, Percent_Identity=35.1274787535411, Blast_Score=197, Evalue=8e-51,
Organism=Caenorhabditis elegans, GI71982793, Length=353, Percent_Identity=35.4107648725212, Blast_Score=196, Evalue=1e-50,
Organism=Saccharomyces cerevisiae, GI6320474, Length=365, Percent_Identity=37.2602739726027, Blast_Score=218, Evalue=1e-57,
Organism=Drosophila melanogaster, GI24666151, Length=353, Percent_Identity=38.8101983002833, Blast_Score=224, Evalue=5e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR002305
- InterPro:   IPR014729
- InterPro:   IPR002306 [H]

Pfam domain/function: PF00579 tRNA-synt_1b [H]

EC number: =6.1.1.2 [H]

Molecular weight: Translated: 39111; Mature: 38980

Theoretical pI: Translated: 6.86; Mature: 6.86

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEFKPLVFSGVQPTGNLHLGNYLGAIRKFVALQDNNDCIYCVVDLHSITAQLVHEDLRG
CCCCCCHHEECCCCCCCEEHHHHHHHHHHHHHEECCCCEEEEEEEHHHHHHHHHHHHHHH
QIRSIAAAFIASGIDPEKHIVFNQSAVPQHAELAWIFNCVARIGWMNRMTQFKDKAGKDR
HHHHHHHHHHHCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
ENASLGLLAYPSLMAADILVYRATHVPVGDDQKQHLELTRDIAQKFNIDFMAHIRARGYG
CCCCEEEEHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHCCHHEEEHHHCCCC
VDIVVGEEPIHAYFPPVEPLIGGPAPRVMSLRDGTKKMSKSDPSDLSRINLMDDADTILK
EEEEECCCCCCCCCCCCHHHCCCCCCCEEEHHHHHHHHCCCCCCHHHHEECCCCHHHHHH
KIRKAKTDPDALPSEADGLKGRPEAENLVGIYAALSDRSKDEVLAEFGGQQFSAFKPALA
HHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHH
DLAVTVLSPITGEMRRLMGDTAHIDAILRKGGERARERAEKTMREVREIIGFLQ
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TEFKPLVFSGVQPTGNLHLGNYLGAIRKFVALQDNNDCIYCVVDLHSITAQLVHEDLRG
CCCCCHHEECCCCCCCEEHHHHHHHHHHHHHEECCCCEEEEEEEHHHHHHHHHHHHHHH
QIRSIAAAFIASGIDPEKHIVFNQSAVPQHAELAWIFNCVARIGWMNRMTQFKDKAGKDR
HHHHHHHHHHHCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
ENASLGLLAYPSLMAADILVYRATHVPVGDDQKQHLELTRDIAQKFNIDFMAHIRARGYG
CCCCEEEEHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHCCHHEEEHHHCCCC
VDIVVGEEPIHAYFPPVEPLIGGPAPRVMSLRDGTKKMSKSDPSDLSRINLMDDADTILK
EEEEECCCCCCCCCCCCHHHCCCCCCCEEEHHHHHHHHCCCCCCHHHHEECCCCHHHHHH
KIRKAKTDPDALPSEADGLKGRPEAENLVGIYAALSDRSKDEVLAEFGGQQFSAFKPALA
HHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHH
DLAVTVLSPITGEMRRLMGDTAHIDAILRKGGERARERAEKTMREVREIIGFLQ
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]