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The map label for this gene is purL

Identifier: 150401881

GI number: 150401881

Start: 1517906

End: 1520104

Strand: Direct

Name: purL

Synonym: Maeo_1459

Alternate gene names: 150401881

Gene position: 1517906-1520104 (Clockwise)

Preceding gene: 150401880

Following gene: 150401882

Centisome position: 96.71

GC content: 34.7

Gene sequence:

>2199_bases
ATGGATTTAAACGATTTGAAATTTATAGAAGAACAATTAGGAAGAAAACCAAATGATGTAGAAATTGGAATGTTTGAAAA
TCTATGGAGTGAGCACTGTTCTTATAGAAGCACAAAAAAATTACTCAGTATGTTTGGGAAAACAGTTAAAGAAAACCAAA
ACATAGTAGTAGGTCCGGGAGACGATGCTGCACTTATAAAAATAGATGACGAAACCGATTTATGTGTTGCCATGGCCATG
GAAAGCCACAACCACCCATCATATATTGACCCATACAATGGGGCAGCAACAGGAGTTGGGGGAATTGTTAGGGATATTAT
ATCAATGAATGCAAAACCCATAGCTTTATTAAATGCCCTTAGATTCGGAGATATAAACGGAGAAGAAAAGGATAAAGTAA
GATGGCTTGTGGAAGGTGTTGTAGATGGAATTAGGGACTATGGAAATAGAATAGGTGTTCCCAATGTGGGGGGAGAATGT
GAATTCGATAAATCCTACGACTACAACAACCTTGTAAATGTGGTATGTATCGGGCTTGTAAAAGAAGGAGATATCGTAAC
TGGAAAAGCAAAAGAAACAGATTTAACTCTTATACTTGTAGGAAGCACCGGAAGAGATGGAATTGGTGGAGCTTCCTTTG
CATCAAAAGACTTAACCAGCGAAAGTGAAGGAGACAGACCAAGTGTTCAAATTGGAGACGCCTTTACAGAAAAATGTGTA
ATAGATTCCACTCTTGAAGCCTGTGCAACTAAAAAAGTTAAGGCAATTAAAGACCTTGGAGCTGCGGGAATAACTTCCTC
CTGTTCGGAGCTCTGCTATAGTGGTGGAGTTGGTGCTGAACTTTACCTTGAAAATGTAATATTAAGAGATGAAGGAATGA
CGGCTTATGAAATAATGGTTTCAGAATCGCAGGAAAGAATGCTCCTTGCAGTAGAAAAAGGAAGCGAAGAAGAAATAATA
AAAATATTTGAAAAATACGAGCTCCCGGTTTCAATTATTGGAAAAACAACAGATACAAAAAGATTTTTCGTAAAAATGAA
TGATGAAGTTGTTGTTGATTTGCCATTGGATTTGCTTTGTGAGGCAACTCTCACAGATAGTGAAGAAAAAGAAACAATAC
TTGAAACACCAGATAATAAAGAAAACATAGCAGAACCAGAACCAGCAGAATTAAACAATATATTATTAAAATTATTAAAA
TCCCCAAATATTAACTCAAAAAAATGGATATATGAACAATATGACCATGAAGTGCAGTTAAATACAGTTGTAAGACCAGG
AAAAGATGCCAGTGTATTGAGATTAAAAGAAGCTCACCCAAAAGCTCTTGCTCTTGTGGCAGATTGTAATCCTACATACT
GTAAGTTAAACCCATATGGGGGAAGTTTAAACCTTGTATGCGAATCAGTTAGGAATTTGGCAACTGTTGGAGCAAAACCG
ATTGGTATGCTCGATAATTTGAATTTTGGTAATCCAGAAAAACCAGAAAGATTTTACCAAATCAAAAAATGTATTGAAGG
ACTTGCAGACGGTGCCGAAATTATTGGTGTTCCCGTAGTGGGCGGAAATGTAAGTTTATACAATGAAACTGTAATTGATG
GAAAAGACTATCCTATAAATCCAACACCAGTAATTAGTATTGTGGGAACTATTGAAAATATCAATAACATACCAAAAGGA
GCAAAAGAAGGGGATATTTTAATAATAACAGCACCAACCAAAGACGAAATGGGAGGAACGGAATACTACAAACAAATCCA
CAACACAGAAGAAGGAATTGTTCCAAAGGCAAATTTGGAAGTTGAAAAAGAAATATACTCAAAAGTTTGTGAATTGGTAA
ATAATGGATTAATAAATGAAGCTGTGGATTGTTCCAAAGGAGGACTTGGTGTAGCAATCTCTAAATTATGTATGACTAAC
AATATTGGTGTAGAATTAGATTTGGGAGACTATAACACCAACGGCTTAAGAAATGATATTTTATTATTCTCAGAGAGCTC
CGGTAGAATAATATTATCAGTAGATAAAAACAATGCCGATAAAGTTGTTAAAGAATTAAATGGTGCAATTATCGGAACTG
TTAAAGGAAATGAGTTAAAAATAAAATTAAACGACAATGAATTAATAAATTTACCTATTGAAGAAATGAAAAATAAATAT
GAAAATGCCTTTTCTGAAATGATGGGAGAAAATATATAA

Upstream 100 bases:

>100_bases
AATACCTCTCTTTTATTAATATAATGATAGTTTATTAATTATATTTTTAATCATATTTATTTTATTATTAATTTTATACA
GATATTAAAGAGGAATAACA

Downstream 100 bases:

>100_bases
AATTCATAATTCATATTTATTATTTTATTTAATGAAATTTCTCTATTTTTTTACTATTGGACGCATAATTATCTATTTAT
TTTAACTATTCGGTGTTAAT

Product: phosphoribosylformylglycinamidine synthase II

Products: NA

Alternate protein names: Phosphoribosylformylglycinamidine synthase II; FGAM synthase II

Number of amino acids: Translated: 732; Mature: 732

Protein sequence:

>732_residues
MDLNDLKFIEEQLGRKPNDVEIGMFENLWSEHCSYRSTKKLLSMFGKTVKENQNIVVGPGDDAALIKIDDETDLCVAMAM
ESHNHPSYIDPYNGAATGVGGIVRDIISMNAKPIALLNALRFGDINGEEKDKVRWLVEGVVDGIRDYGNRIGVPNVGGEC
EFDKSYDYNNLVNVVCIGLVKEGDIVTGKAKETDLTLILVGSTGRDGIGGASFASKDLTSESEGDRPSVQIGDAFTEKCV
IDSTLEACATKKVKAIKDLGAAGITSSCSELCYSGGVGAELYLENVILRDEGMTAYEIMVSESQERMLLAVEKGSEEEII
KIFEKYELPVSIIGKTTDTKRFFVKMNDEVVVDLPLDLLCEATLTDSEEKETILETPDNKENIAEPEPAELNNILLKLLK
SPNINSKKWIYEQYDHEVQLNTVVRPGKDASVLRLKEAHPKALALVADCNPTYCKLNPYGGSLNLVCESVRNLATVGAKP
IGMLDNLNFGNPEKPERFYQIKKCIEGLADGAEIIGVPVVGGNVSLYNETVIDGKDYPINPTPVISIVGTIENINNIPKG
AKEGDILIITAPTKDEMGGTEYYKQIHNTEEGIVPKANLEVEKEIYSKVCELVNNGLINEAVDCSKGGLGVAISKLCMTN
NIGVELDLGDYNTNGLRNDILLFSESSGRIILSVDKNNADKVVKELNGAIIGTVKGNELKIKLNDNELINLPIEEMKNKY
ENAFSEMMGENI

Sequences:

>Translated_732_residues
MDLNDLKFIEEQLGRKPNDVEIGMFENLWSEHCSYRSTKKLLSMFGKTVKENQNIVVGPGDDAALIKIDDETDLCVAMAM
ESHNHPSYIDPYNGAATGVGGIVRDIISMNAKPIALLNALRFGDINGEEKDKVRWLVEGVVDGIRDYGNRIGVPNVGGEC
EFDKSYDYNNLVNVVCIGLVKEGDIVTGKAKETDLTLILVGSTGRDGIGGASFASKDLTSESEGDRPSVQIGDAFTEKCV
IDSTLEACATKKVKAIKDLGAAGITSSCSELCYSGGVGAELYLENVILRDEGMTAYEIMVSESQERMLLAVEKGSEEEII
KIFEKYELPVSIIGKTTDTKRFFVKMNDEVVVDLPLDLLCEATLTDSEEKETILETPDNKENIAEPEPAELNNILLKLLK
SPNINSKKWIYEQYDHEVQLNTVVRPGKDASVLRLKEAHPKALALVADCNPTYCKLNPYGGSLNLVCESVRNLATVGAKP
IGMLDNLNFGNPEKPERFYQIKKCIEGLADGAEIIGVPVVGGNVSLYNETVIDGKDYPINPTPVISIVGTIENINNIPKG
AKEGDILIITAPTKDEMGGTEYYKQIHNTEEGIVPKANLEVEKEIYSKVCELVNNGLINEAVDCSKGGLGVAISKLCMTN
NIGVELDLGDYNTNGLRNDILLFSESSGRIILSVDKNNADKVVKELNGAIIGTVKGNELKIKLNDNELINLPIEEMKNKY
ENAFSEMMGENI
>Mature_732_residues
MDLNDLKFIEEQLGRKPNDVEIGMFENLWSEHCSYRSTKKLLSMFGKTVKENQNIVVGPGDDAALIKIDDETDLCVAMAM
ESHNHPSYIDPYNGAATGVGGIVRDIISMNAKPIALLNALRFGDINGEEKDKVRWLVEGVVDGIRDYGNRIGVPNVGGEC
EFDKSYDYNNLVNVVCIGLVKEGDIVTGKAKETDLTLILVGSTGRDGIGGASFASKDLTSESEGDRPSVQIGDAFTEKCV
IDSTLEACATKKVKAIKDLGAAGITSSCSELCYSGGVGAELYLENVILRDEGMTAYEIMVSESQERMLLAVEKGSEEEII
KIFEKYELPVSIIGKTTDTKRFFVKMNDEVVVDLPLDLLCEATLTDSEEKETILETPDNKENIAEPEPAELNNILLKLLK
SPNINSKKWIYEQYDHEVQLNTVVRPGKDASVLRLKEAHPKALALVADCNPTYCKLNPYGGSLNLVCESVRNLATVGAKP
IGMLDNLNFGNPEKPERFYQIKKCIEGLADGAEIIGVPVVGGNVSLYNETVIDGKDYPINPTPVISIVGTIENINNIPKG
AKEGDILIITAPTKDEMGGTEYYKQIHNTEEGIVPKANLEVEKEIYSKVCELVNNGLINEAVDCSKGGLGVAISKLCMTN
NIGVELDLGDYNTNGLRNDILLFSESSGRIILSVDKNNADKVVKELNGAIIGTVKGNELKIKLNDNELINLPIEEMKNKY
ENAFSEMMGENI

Specific function: Unknown

COG id: COG0046

COG function: function code F; Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGAMS family

Homologues:

Organism=Escherichia coli, GI48994899, Length=783, Percent_Identity=23.4993614303959, Blast_Score=122, Evalue=9e-29,
Organism=Saccharomyces cerevisiae, GI6321498, Length=479, Percent_Identity=24.6346555323591, Blast_Score=100, Evalue=9e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PURL_META3 (A6UX13)

Other databases:

- EMBL:   CP000743
- RefSeq:   YP_001325647.1
- ProteinModelPortal:   A6UX13
- SMR:   A6UX13
- STRING:   A6UX13
- GeneID:   5326931
- GenomeReviews:   CP000743_GR
- KEGG:   mae:Maeo_1459
- eggNOG:   arNOG04101
- HOGENOM:   HBG311214
- OMA:   YGNSFGV
- ProtClustDB:   PRK01213
- BioCyc:   MAEO419665:MAEO_1459-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00420
- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR010074
- InterPro:   IPR016188
- TIGRFAMs:   TIGR01736

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C; SSF56042 AIR_synth_C; SSF55326 PurM_N-like

EC number: =6.3.5.3

Molecular weight: Translated: 79930; Mature: 79930

Theoretical pI: Translated: 4.37; Mature: 4.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLNDLKFIEEQLGRKPNDVEIGMFENLWSEHCSYRSTKKLLSMFGKTVKENQNIVVGPG
CCCHHHHHHHHHHCCCCCCEEECHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCEEEECC
DDAALIKIDDETDLCVAMAMESHNHPSYIDPYNGAATGVGGIVRDIISMNAKPIALLNAL
CCEEEEEECCCCCEEEEEEHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHH
RFGDINGEEKDKVRWLVEGVVDGIRDYGNRIGVPNVGGECEFDKSYDYNNLVNVVCIGLV
HHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHEEEEEEEEE
KEGDIVTGKAKETDLTLILVGSTGRDGIGGASFASKDLTSESEGDRPSVQIGDAFTEKCV
ECCCEEECCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCHHHHHHH
IDSTLEACATKKVKAIKDLGAAGITSSCSELCYSGGVGAELYLENVILRDEGMTAYEIMV
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCHHEEEEEEEEECCCCEEEEEEE
SESQERMLLAVEKGSEEEIIKIFEKYELPVSIIGKTTDTKRFFVKMNDEVVVDLPLDLLC
CCCCCEEEEEEECCCHHHHHHHHHHHCCCEEEECCCCCCEEEEEEECCCEEEECCHHHHE
EATLTDSEEKETILETPDNKENIAEPEPAELNNILLKLLKSPNINSKKWIYEQYDHEVQL
ECCCCCCCCCHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHCCCEEEE
NTVVRPGKDASVLRLKEAHPKALALVADCNPTYCKLNPYGGSLNLVCESVRNLATVGAKP
EEEECCCCCCCEEEEECCCCCEEEEEECCCCCEEEECCCCCCHHHHHHHHHHHHHCCCCC
IGMLDNLNFGNPEKPERFYQIKKCIEGLADGAEIIGVPVVGGNVSLYNETVIDGKDYPIN
CCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEEECCCEEEEEEEEECCCCCCCC
PTPVISIVGTIENINNIPKGAKEGDILIITAPTKDEMGGTEYYKQIHNTEEGIVPKANLE
CCCCEEEEEEHHHHHCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHCCCCCCCCCCCCC
VEKEIYSKVCELVNNGLINEAVDCSKGGLGVAISKLCMTNNIGVELDLGDYNTNGLRNDI
HHHHHHHHHHHHHHCCCCHHHCCCCCCCHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCE
LLFSESSGRIILSVDKNNADKVVKELNGAIIGTVKGNELKIKLNDNELINLPIEEMKNKY
EEEECCCCEEEEEECCCCHHHHHHHHCCCEEEEEECCEEEEEECCCCEEECCHHHHHHHH
ENAFSEMMGENI
HHHHHHHHCCCC
>Mature Secondary Structure
MDLNDLKFIEEQLGRKPNDVEIGMFENLWSEHCSYRSTKKLLSMFGKTVKENQNIVVGPG
CCCHHHHHHHHHHCCCCCCEEECHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCEEEECC
DDAALIKIDDETDLCVAMAMESHNHPSYIDPYNGAATGVGGIVRDIISMNAKPIALLNAL
CCEEEEEECCCCCEEEEEEHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHH
RFGDINGEEKDKVRWLVEGVVDGIRDYGNRIGVPNVGGECEFDKSYDYNNLVNVVCIGLV
HHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHEEEEEEEEE
KEGDIVTGKAKETDLTLILVGSTGRDGIGGASFASKDLTSESEGDRPSVQIGDAFTEKCV
ECCCEEECCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCHHHHHHH
IDSTLEACATKKVKAIKDLGAAGITSSCSELCYSGGVGAELYLENVILRDEGMTAYEIMV
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCHHEEEEEEEEECCCCEEEEEEE
SESQERMLLAVEKGSEEEIIKIFEKYELPVSIIGKTTDTKRFFVKMNDEVVVDLPLDLLC
CCCCCEEEEEEECCCHHHHHHHHHHHCCCEEEECCCCCCEEEEEEECCCEEEECCHHHHE
EATLTDSEEKETILETPDNKENIAEPEPAELNNILLKLLKSPNINSKKWIYEQYDHEVQL
ECCCCCCCCCHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHCCCEEEE
NTVVRPGKDASVLRLKEAHPKALALVADCNPTYCKLNPYGGSLNLVCESVRNLATVGAKP
EEEECCCCCCCEEEEECCCCCEEEEEECCCCCEEEECCCCCCHHHHHHHHHHHHHCCCCC
IGMLDNLNFGNPEKPERFYQIKKCIEGLADGAEIIGVPVVGGNVSLYNETVIDGKDYPIN
CCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEEECCCEEEEEEEEECCCCCCCC
PTPVISIVGTIENINNIPKGAKEGDILIITAPTKDEMGGTEYYKQIHNTEEGIVPKANLE
CCCCEEEEEEHHHHHCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHCCCCCCCCCCCCC
VEKEIYSKVCELVNNGLINEAVDCSKGGLGVAISKLCMTNNIGVELDLGDYNTNGLRNDI
HHHHHHHHHHHHHHCCCCHHHCCCCCCCHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCE
LLFSESSGRIILSVDKNNADKVVKELNGAIIGTVKGNELKIKLNDNELINLPIEEMKNKY
EEEECCCCEEEEEECCCCHHHHHHHHCCCEEEEEECCEEEEEECCCCEEECCHHHHHHHH
ENAFSEMMGENI
HHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA