Click here to switch to the map view.

The map label for this gene is 150400309

Identifier: 150400309

GI number: 150400309

Start: 1584865

End: 1586772

Strand: Reverse

Name: 150400309

Synonym: Mevan_1572

Alternate gene names: NA

Gene position: 1586772-1584865 (Counterclockwise)

Preceding gene: 150400310

Following gene: 150400307

Centisome position: 92.25

GC content: 37.32

Gene sequence:

>1908_bases
TTGTCAGCGGAAGATATATTAAACGAGATAAAGGCTGAAGTTATACGCAAAGCCCCAGGAAATGCGGTAATTACGGATGT
CGAATTTGAAGGTTCAGAAGTAGTAATTTATGCAAAAAATCCAGAACTTTTTTCAAACAGTATTATAAAAGAATTTGCAA
GGGATTTTAGAAAAAGGCTTGCAATAAGGCCTGATCCTTCTGTTTTAGTCGAACCTGAAGTCGCAAAAGAGCAGATTTTA
AAGATAGTTCCTGAAGATGCTGAAGTTACAAACTGCGTGTTTGATGCAAATACTGGCGAAGTAATTATCGAATCAAAAAA
ACCGGGACTTGTAATTGGAAAAGAAGGCTCAACCCTTGAAGATATTAAAAAAGCAATTCAATGGGCCCCAAAACCAGTTA
GGACTCCACCAATTCCATCAGATACTATTAAAGCCATTAGGGCTACAATGTATCGTGAAAGAACGGATGTAAAAGATATT
TTAAGGAGAATTGGAAGAAGAATACATAGGGATGTACGATTGAGAGACGATTCATGGATTAGAACTTCTTTTTTAGGCGG
GAGTAGGGAAGTTGGAAGAACATGTATCTACCACCAAACTCCGGAAAGTAGAATTTTAGTGGATTGCGGTATTAACATTG
CAGTAGATGACGAAAAAGCTTTTCCACATTTTGATGCGCCGGAATTTTCAATTGATGAAATCGATGCTGTTGTTGTAACT
CATGCCCACCTTGACCATTGTGGATTTATTCCAGGATTATTTAGGTATGGCTATGATGGGCCAGTATATTGTACAAAACC
AACTAGAGATTTGATGACCCTTCTACAAAAAGACTACGTTGAAATTAGCGAAAAAGAAGGAAAGAATGTTCCATATTCCT
CAAAAGATATTAAAAACGCAATAAAGCATACAATACCTCTTGATTATGGCGTTACCACAGATATTGCACCTGCAATTAAA
TTAACATTACATAATGCAGGGCATATCTTGGGTTCCGCAATTTCACACTGTCACGTTGGAGATGGACTCTATAACGTTGC
ATACACAGGAGATATTAAATTTGAAGCTTCAAGATTATTAGAACCTGCAACATGCCAATTCCCAAGACTTGAAACACTCA
TTATTGAATCCACGTATGGGGGGTACGATGACGTACTTCCAGAAAGAGATGAAACTGAAAAAGAGTTCTTAAATGTAATG
TTGGAGACCACCTCTAGGGGCGGAAAAGTAATCATTCCCGTATTTGGTATTGGAAGAGCCCAAGAACTAATGCTTGTTTT
AGAAGAAGGATATAATCAAGGTATATTCAATGCTCCAGTTTACCTTGATGGTATGATATGGGAAGCTACTGCAATTCACA
CCGCTTATCCAGAATATTTATCTAAAGCGATGAGAAACAGGATATTCCATGAAGGAGATAATCCATTCCTTTCAGAAGTA
TTCAAAAAAGTTAAGAATACAAACGACAGGAGAAACATCATGGATGGAGATGAAGCTTGTATCATTCTTACAACTTCAGG
CATGCTTAGTGGTGGCCCGAGTGTTGAATACTTTAAGAATCTTGCAGAAGATGAAAAGAACGCAATCGTGTTTGTAGGGT
ATCAATCTGAAGGAACATTGGGTAGAAAAATCCAGAGAGGATTTAAAGAGATTCCCCTAATGGGTAAGAACGGAAGGAGT
AAAGCTGTAAAGGTAAACCTTTCAGTTCATACCTTAGAAGGGTTTTCAGGGCATAGTGATAGAAAGCAGTTGATAAAATA
CTTAAGAAAGTTAAAACCAATTCCAGACCGTATATTAACGGTTCACGGTGAAGCTTCAAAGTGTATTGATCTTGCAAGTA
CTGCATATAAACTCTTTAAAAAAGAAACCCGTTCACCAATGAATCTTGATTCTATAAGGCTTAGGTAA

Upstream 100 bases:

>100_bases
AAAAGGATTCTTTTCAAATTTTTTTTATGATTTTAAAACATCAAACAATTTTATAGGCGTTTTCCGAATTTAAACACAAT
ACTACATAGGAGGGACTATT

Downstream 100 bases:

>100_bases
TTGAAATTACTTAAAATTAATTAAAATTATTTTTTTAGCTATTACTTTAAAATTTATTTTTTATTTTTTCCGTTTAAGTT
AAAAGTTTTTTAAAAAAGTA

Product: beta-lactamase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 635; Mature: 634

Protein sequence:

>635_residues
MSAEDILNEIKAEVIRKAPGNAVITDVEFEGSEVVIYAKNPELFSNSIIKEFARDFRKRLAIRPDPSVLVEPEVAKEQIL
KIVPEDAEVTNCVFDANTGEVIIESKKPGLVIGKEGSTLEDIKKAIQWAPKPVRTPPIPSDTIKAIRATMYRERTDVKDI
LRRIGRRIHRDVRLRDDSWIRTSFLGGSREVGRTCIYHQTPESRILVDCGINIAVDDEKAFPHFDAPEFSIDEIDAVVVT
HAHLDHCGFIPGLFRYGYDGPVYCTKPTRDLMTLLQKDYVEISEKEGKNVPYSSKDIKNAIKHTIPLDYGVTTDIAPAIK
LTLHNAGHILGSAISHCHVGDGLYNVAYTGDIKFEASRLLEPATCQFPRLETLIIESTYGGYDDVLPERDETEKEFLNVM
LETTSRGGKVIIPVFGIGRAQELMLVLEEGYNQGIFNAPVYLDGMIWEATAIHTAYPEYLSKAMRNRIFHEGDNPFLSEV
FKKVKNTNDRRNIMDGDEACIILTTSGMLSGGPSVEYFKNLAEDEKNAIVFVGYQSEGTLGRKIQRGFKEIPLMGKNGRS
KAVKVNLSVHTLEGFSGHSDRKQLIKYLRKLKPIPDRILTVHGEASKCIDLASTAYKLFKKETRSPMNLDSIRLR

Sequences:

>Translated_635_residues
MSAEDILNEIKAEVIRKAPGNAVITDVEFEGSEVVIYAKNPELFSNSIIKEFARDFRKRLAIRPDPSVLVEPEVAKEQIL
KIVPEDAEVTNCVFDANTGEVIIESKKPGLVIGKEGSTLEDIKKAIQWAPKPVRTPPIPSDTIKAIRATMYRERTDVKDI
LRRIGRRIHRDVRLRDDSWIRTSFLGGSREVGRTCIYHQTPESRILVDCGINIAVDDEKAFPHFDAPEFSIDEIDAVVVT
HAHLDHCGFIPGLFRYGYDGPVYCTKPTRDLMTLLQKDYVEISEKEGKNVPYSSKDIKNAIKHTIPLDYGVTTDIAPAIK
LTLHNAGHILGSAISHCHVGDGLYNVAYTGDIKFEASRLLEPATCQFPRLETLIIESTYGGYDDVLPERDETEKEFLNVM
LETTSRGGKVIIPVFGIGRAQELMLVLEEGYNQGIFNAPVYLDGMIWEATAIHTAYPEYLSKAMRNRIFHEGDNPFLSEV
FKKVKNTNDRRNIMDGDEACIILTTSGMLSGGPSVEYFKNLAEDEKNAIVFVGYQSEGTLGRKIQRGFKEIPLMGKNGRS
KAVKVNLSVHTLEGFSGHSDRKQLIKYLRKLKPIPDRILTVHGEASKCIDLASTAYKLFKKETRSPMNLDSIRLR
>Mature_634_residues
SAEDILNEIKAEVIRKAPGNAVITDVEFEGSEVVIYAKNPELFSNSIIKEFARDFRKRLAIRPDPSVLVEPEVAKEQILK
IVPEDAEVTNCVFDANTGEVIIESKKPGLVIGKEGSTLEDIKKAIQWAPKPVRTPPIPSDTIKAIRATMYRERTDVKDIL
RRIGRRIHRDVRLRDDSWIRTSFLGGSREVGRTCIYHQTPESRILVDCGINIAVDDEKAFPHFDAPEFSIDEIDAVVVTH
AHLDHCGFIPGLFRYGYDGPVYCTKPTRDLMTLLQKDYVEISEKEGKNVPYSSKDIKNAIKHTIPLDYGVTTDIAPAIKL
TLHNAGHILGSAISHCHVGDGLYNVAYTGDIKFEASRLLEPATCQFPRLETLIIESTYGGYDDVLPERDETEKEFLNVML
ETTSRGGKVIIPVFGIGRAQELMLVLEEGYNQGIFNAPVYLDGMIWEATAIHTAYPEYLSKAMRNRIFHEGDNPFLSEVF
KKVKNTNDRRNIMDGDEACIILTTSGMLSGGPSVEYFKNLAEDEKNAIVFVGYQSEGTLGRKIQRGFKEIPLMGKNGRSK
AVKVNLSVHTLEGFSGHSDRKQLIKYLRKLKPIPDRILTVHGEASKCIDLASTAYKLFKKETRSPMNLDSIRLR

Specific function: Unknown

COG id: COG1782

COG function: function code R; Predicted metal-dependent RNase, consists of a metallo-beta-lactamase domain and an RNA-binding KH domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI33300633, Length=461, Percent_Identity=31.0195227765727, Blast_Score=226, Evalue=7e-59,
Organism=Homo sapiens, GI7706427, Length=460, Percent_Identity=29.7826086956522, Blast_Score=211, Evalue=1e-54,
Organism=Homo sapiens, GI34101288, Length=376, Percent_Identity=23.4042553191489, Blast_Score=88, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI32564696, Length=468, Percent_Identity=31.1965811965812, Blast_Score=213, Evalue=3e-55,
Organism=Caenorhabditis elegans, GI32566029, Length=463, Percent_Identity=30.8855291576674, Blast_Score=189, Evalue=6e-48,
Organism=Caenorhabditis elegans, GI17559452, Length=379, Percent_Identity=22.6912928759894, Blast_Score=79, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6323307, Length=442, Percent_Identity=29.4117647058824, Blast_Score=177, Evalue=4e-45,
Organism=Drosophila melanogaster, GI21358523, Length=455, Percent_Identity=31.8681318681319, Blast_Score=227, Evalue=2e-59,
Organism=Drosophila melanogaster, GI24648013, Length=444, Percent_Identity=29.954954954955, Blast_Score=207, Evalue=2e-53,
Organism=Drosophila melanogaster, GI21358013, Length=378, Percent_Identity=24.3386243386243, Blast_Score=90, Evalue=6e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022712
- InterPro:   IPR001279
- InterPro:   IPR004087
- InterPro:   IPR019975
- InterPro:   IPR004044
- InterPro:   IPR011108 [H]

Pfam domain/function: PF10996 Beta-Casp; PF07650 KH_2; PF00753 Lactamase_B; PF07521 RMMBL [H]

EC number: NA

Molecular weight: Translated: 71242; Mature: 71111

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAEDILNEIKAEVIRKAPGNAVITDVEFEGSEVVIYAKNPELFSNSIIKEFARDFRKRL
CCHHHHHHHHHHHHHHCCCCCEEEEEEEECCCEEEEEECCCCHHHHHHHHHHHHHHHHHC
AIRPDPSVLVEPEVAKEQILKIVPEDAEVTNCVFDANTGEVIIESKKPGLVIGKEGSTLE
CCCCCCCEEECCHHHHHHHHHHCCCCCCCEEEEEECCCCCEEEECCCCCEEEECCCCCHH
DIKKAIQWAPKPVRTPPIPSDTIKAIRATMYRERTDVKDILRRIGRRIHRDVRLRDDSWI
HHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCEECCCCEE
RTSFLGGSREVGRTCIYHQTPESRILVDCGINIAVDDEKAFPHFDAPEFSIDEIDAVVVT
EEHHCCCCHHHCCEEEEECCCCCCEEEEECCEEEECCCCCCCCCCCCCCCHHHHCEEEEE
HAHLDHCGFIPGLFRYGYDGPVYCTKPTRDLMTLLQKDYVEISEKEGKNVPYSSKDIKNA
ECHHHHCCCHHHHHHCCCCCCEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
IKHTIPLDYGVTTDIAPAIKLTLHNAGHILGSAISHCHVGDGLYNVAYTGDIKFEASRLL
HHHCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHCCCCCCEEEEEEECCEEEEHHHCC
EPATCQFPRLETLIIESTYGGYDDVLPERDETEKEFLNVMLETTSRGGKVIIPVFGIGRA
CCCCCCCCCCEEEEEECCCCCCHHCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEECCCCH
QELMLVLEEGYNQGIFNAPVYLDGMIWEATAIHTAYPEYLSKAMRNRIFHEGDNPFLSEV
HHHHHHHHCCCCCCCCCCCEEECCEEEEHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHH
FKKVKNTNDRRNIMDGDEACIILTTSGMLSGGPSVEYFKNLAEDEKNAIVFVGYQSEGTL
HHHHHCCCCCCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHCCCCCEEEEEEECCCCCH
GRKIQRGFKEIPLMGKNGRSKAVKVNLSVHTLEGFSGHSDRKQLIKYLRKLKPIPDRILT
HHHHHHHHHHCCCCCCCCCCCEEEEEEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCEEE
VHGEASKCIDLASTAYKLFKKETRSPMNLDSIRLR
EECCHHHHHHHHHHHHHHHHHHCCCCCCCCCEECC
>Mature Secondary Structure 
SAEDILNEIKAEVIRKAPGNAVITDVEFEGSEVVIYAKNPELFSNSIIKEFARDFRKRL
CHHHHHHHHHHHHHHCCCCCEEEEEEEECCCEEEEEECCCCHHHHHHHHHHHHHHHHHC
AIRPDPSVLVEPEVAKEQILKIVPEDAEVTNCVFDANTGEVIIESKKPGLVIGKEGSTLE
CCCCCCCEEECCHHHHHHHHHHCCCCCCCEEEEEECCCCCEEEECCCCCEEEECCCCCHH
DIKKAIQWAPKPVRTPPIPSDTIKAIRATMYRERTDVKDILRRIGRRIHRDVRLRDDSWI
HHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCEECCCCEE
RTSFLGGSREVGRTCIYHQTPESRILVDCGINIAVDDEKAFPHFDAPEFSIDEIDAVVVT
EEHHCCCCHHHCCEEEEECCCCCCEEEEECCEEEECCCCCCCCCCCCCCCHHHHCEEEEE
HAHLDHCGFIPGLFRYGYDGPVYCTKPTRDLMTLLQKDYVEISEKEGKNVPYSSKDIKNA
ECHHHHCCCHHHHHHCCCCCCEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
IKHTIPLDYGVTTDIAPAIKLTLHNAGHILGSAISHCHVGDGLYNVAYTGDIKFEASRLL
HHHCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHCCCCCCEEEEEEECCEEEEHHHCC
EPATCQFPRLETLIIESTYGGYDDVLPERDETEKEFLNVMLETTSRGGKVIIPVFGIGRA
CCCCCCCCCCEEEEEECCCCCCHHCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEECCCCH
QELMLVLEEGYNQGIFNAPVYLDGMIWEATAIHTAYPEYLSKAMRNRIFHEGDNPFLSEV
HHHHHHHHCCCCCCCCCCCEEECCEEEEHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHH
FKKVKNTNDRRNIMDGDEACIILTTSGMLSGGPSVEYFKNLAEDEKNAIVFVGYQSEGTL
HHHHHCCCCCCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHCCCCCEEEEEEECCCCCH
GRKIQRGFKEIPLMGKNGRSKAVKVNLSVHTLEGFSGHSDRKQLIKYLRKLKPIPDRILT
HHHHHHHHHHCCCCCCCCCCCEEEEEEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCEEE
VHGEASKCIDLASTAYKLFKKETRSPMNLDSIRLR
EECCHHHHHHHHHHHHHHHHHHCCCCCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]