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The map label for this gene is psmB

Identifier: 150400310

GI number: 150400310

Start: 1586921

End: 1587580

Strand: Reverse

Name: psmB

Synonym: Mevan_1573

Alternate gene names: 150400310

Gene position: 1587580-1586921 (Counterclockwise)

Preceding gene: 150400311

Following gene: 150400309

Centisome position: 92.3

GC content: 36.67

Gene sequence:

>660_bases
ATGATATCAGGCAGCGAATACCATAAGGAATACATGAAAGGAACAACTACCGTAGGATTAATTTGTGAAGATGGCGTTGT
TTTAGCTACTGACAAAAGAGCTACAATGGGTAACCTCATTGCTGACAAAGAAGCGAAAAAGTTATATAAGATTGATGACT
ACATAGCAATGACTATAGCTGGAAGTGTAGGGGATGCCCAATCACTCATCAGGTTGCTTTCTGCGGAAGCTAAAATATAC
AAGATGAGAACTGGAAATAACATGACTCCACTTTCCTGTACTACGTTAACAAGTAATGTCTTACATGGTAACAGGCATTA
TCCTCTTTTAACACAATTAATAATTGGTGGATACGACCTTATCAATGGACCAAAATTGTTTTCACTCGACCCTGTTGGAG
GCATTAATGAAGAATCTTCATTTACGGCCACAGGTTCAGGTTCACCTACTGCTTACGGAGTACTTGAAGCAGAGTATAAA
TCCGAAATCAACATTGAAAAAGGCTTACTTATTGCAGTAAAAGCCCTTATATCCGCAATGCAAAGAGATGCATACTCTGG
AAACGGAATTTCGTTAGCAAAGATAGATAAAACTGGAGTAACATTATATTCTGATGAAGAAATTGAAAACTTGGTAAAAA
AAGTAACTAAAAAGAAATAA

Upstream 100 bases:

>100_bases
AAATTCATTGTTTTCTAAATACTACTATTTCTTTTATTTTTAAAACCGTAGACTATATAAAGAATATATTATAAATTGAT
TTATATTAAATGGTGATACG

Downstream 100 bases:

>100_bases
CTACTTAAACGTACTATTTTTATAGTACAATATCAATTACAATTATTGAAAAGGATTCTTTTCAAATTTTTTTTATGATT
TTAAAACATCAAACAATTTT

Product: proteasome endopeptidase complex

Products: NA

Alternate protein names: 20S proteasome beta subunit; Proteasome core protein PsmB

Number of amino acids: Translated: 219; Mature: 219

Protein sequence:

>219_residues
MISGSEYHKEYMKGTTTVGLICEDGVVLATDKRATMGNLIADKEAKKLYKIDDYIAMTIAGSVGDAQSLIRLLSAEAKIY
KMRTGNNMTPLSCTTLTSNVLHGNRHYPLLTQLIIGGYDLINGPKLFSLDPVGGINEESSFTATGSGSPTAYGVLEAEYK
SEINIEKGLLIAVKALISAMQRDAYSGNGISLAKIDKTGVTLYSDEEIENLVKKVTKKK

Sequences:

>Translated_219_residues
MISGSEYHKEYMKGTTTVGLICEDGVVLATDKRATMGNLIADKEAKKLYKIDDYIAMTIAGSVGDAQSLIRLLSAEAKIY
KMRTGNNMTPLSCTTLTSNVLHGNRHYPLLTQLIIGGYDLINGPKLFSLDPVGGINEESSFTATGSGSPTAYGVLEAEYK
SEINIEKGLLIAVKALISAMQRDAYSGNGISLAKIDKTGVTLYSDEEIENLVKKVTKKK
>Mature_219_residues
MISGSEYHKEYMKGTTTVGLICEDGVVLATDKRATMGNLIADKEAKKLYKIDDYIAMTIAGSVGDAQSLIRLLSAEAKIY
KMRTGNNMTPLSCTTLTSNVLHGNRHYPLLTQLIIGGYDLINGPKLFSLDPVGGINEESSFTATGSGSPTAYGVLEAEYK
SEINIEKGLLIAVKALISAMQRDAYSGNGISLAKIDKTGVTLYSDEEIENLVKKVTKKK

Specific function: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation

COG id: COG0638

COG function: function code O; 20S proteasome, alpha and beta subunits

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase T1B family

Homologues:

Organism=Homo sapiens, GI4506201, Length=207, Percent_Identity=31.4009661835749, Blast_Score=110, Evalue=8e-25,
Organism=Homo sapiens, GI73747875, Length=205, Percent_Identity=29.2682926829268, Blast_Score=99, Evalue=2e-21,
Organism=Homo sapiens, GI4758970, Length=205, Percent_Identity=29.2682926829268, Blast_Score=99, Evalue=3e-21,
Organism=Homo sapiens, GI4506191, Length=189, Percent_Identity=31.7460317460317, Blast_Score=91, Evalue=5e-19,
Organism=Homo sapiens, GI23110925, Length=194, Percent_Identity=32.9896907216495, Blast_Score=91, Evalue=6e-19,
Organism=Homo sapiens, GI4506193, Length=198, Percent_Identity=28.2828282828283, Blast_Score=89, Evalue=2e-18,
Organism=Homo sapiens, GI4506203, Length=197, Percent_Identity=27.9187817258883, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI153791216, Length=187, Percent_Identity=28.8770053475936, Blast_Score=81, Evalue=7e-16,
Organism=Homo sapiens, GI22538465, Length=184, Percent_Identity=24.4565217391304, Blast_Score=78, Evalue=7e-15,
Organism=Homo sapiens, GI195539356, Length=158, Percent_Identity=28.4810126582279, Blast_Score=77, Evalue=8e-15,
Organism=Homo sapiens, GI4506205, Length=191, Percent_Identity=26.7015706806283, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI23110942, Length=221, Percent_Identity=27.6018099547511, Blast_Score=71, Evalue=9e-13,
Organism=Homo sapiens, GI4506189, Length=215, Percent_Identity=27.4418604651163, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI222144262, Length=110, Percent_Identity=31.8181818181818, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI156713442, Length=209, Percent_Identity=25.8373205741627, Blast_Score=65, Evalue=4e-11,
Organism=Homo sapiens, GI4506185, Length=209, Percent_Identity=25.8373205741627, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17508499, Length=196, Percent_Identity=29.5918367346939, Blast_Score=95, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17508495, Length=185, Percent_Identity=30.8108108108108, Blast_Score=85, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17535357, Length=191, Percent_Identity=25.130890052356, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17541700, Length=192, Percent_Identity=27.0833333333333, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17508491, Length=220, Percent_Identity=28.1818181818182, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17554384, Length=202, Percent_Identity=24.2574257425743, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17508493, Length=192, Percent_Identity=27.0833333333333, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6325360, Length=206, Percent_Identity=27.6699029126214, Blast_Score=111, Evalue=8e-26,
Organism=Saccharomyces cerevisiae, GI6324731, Length=183, Percent_Identity=27.8688524590164, Blast_Score=75, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6321574, Length=216, Percent_Identity=26.3888888888889, Blast_Score=74, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6322459, Length=196, Percent_Identity=26.0204081632653, Blast_Score=74, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6321692, Length=229, Percent_Identity=27.5109170305677, Blast_Score=70, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6320849, Length=191, Percent_Identity=23.0366492146597, Blast_Score=63, Evalue=3e-11,
Organism=Drosophila melanogaster, GI20130281, Length=190, Percent_Identity=30.5263157894737, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI21355573, Length=186, Percent_Identity=32.258064516129, Blast_Score=99, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24652553, Length=186, Percent_Identity=32.258064516129, Blast_Score=99, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24639979, Length=205, Percent_Identity=31.7073170731707, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24584895, Length=212, Percent_Identity=26.8867924528302, Blast_Score=94, Evalue=6e-20,
Organism=Drosophila melanogaster, GI28573221, Length=217, Percent_Identity=26.2672811059908, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24664391, Length=193, Percent_Identity=28.4974093264249, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24653999, Length=187, Percent_Identity=26.7379679144385, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI21355629, Length=189, Percent_Identity=23.2804232804233, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI281360341, Length=232, Percent_Identity=27.5862068965517, Blast_Score=71, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24586406, Length=232, Percent_Identity=27.5862068965517, Blast_Score=71, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24586400, Length=232, Percent_Identity=27.5862068965517, Blast_Score=71, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24586402, Length=232, Percent_Identity=27.5862068965517, Blast_Score=71, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24581176, Length=198, Percent_Identity=25.2525252525253, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI17933602, Length=183, Percent_Identity=26.2295081967213, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI19922898, Length=152, Percent_Identity=27.6315789473684, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24654391, Length=222, Percent_Identity=23.8738738738739, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24654389, Length=222, Percent_Identity=23.8738738738739, Blast_Score=65, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PSB_METVS (A6USJ3)

Other databases:

- EMBL:   CP000742
- RefSeq:   YP_001324077.1
- ProteinModelPortal:   A6USJ3
- SMR:   A6USJ3
- MEROPS:   T01.002
- GeneID:   5325540
- GenomeReviews:   CP000742_GR
- KEGG:   mvn:Mevan_1573
- eggNOG:   arNOG10234
- HOGENOM:   HBG499923
- OMA:   MAYGVLE
- ProtClustDB:   CLSK876502
- GO:   GO:0005737
- HAMAP:   MF_02113_A
- InterPro:   IPR019983
- InterPro:   IPR000243
- InterPro:   IPR016050
- InterPro:   IPR001353
- PRINTS:   PR00141
- TIGRFAMs:   TIGR03634

Pfam domain/function: PF00227 Proteasome

EC number: =3.4.25.1

Molecular weight: Translated: 23622; Mature: 23622

Theoretical pI: Translated: 7.49; Mature: 7.49

Prosite motif: PS00854 PROTEASOME_B_1; PS51476 PROTEASOME_B_2

Important sites: ACT_SITE 15-15

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISGSEYHKEYMKGTTTVGLICEDGVVLATDKRATMGNLIADKEAKKLYKIDDYIAMTIA
CCCCHHHHHHHHCCCCEEEEEECCCEEEEECCCCHHHHHHHCHHHHHHHHHCCEEEEEEE
GSVGDAQSLIRLLSAEAKIYKMRTGNNMTPLSCTTLTSNVLHGNRHYPLLTQLIIGGYDL
CCCCCHHHHHHHHHCCCEEEEEECCCCCCCEEHHHHHHHHHCCCCCCHHHHHHHHCCEEE
INGPKLFSLDPVGGINEESSFTATGSGSPTAYGVLEAEYKSEINIEKGLLIAVKALISAM
CCCCEEEEECCCCCCCCCCCEEECCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHH
QRDAYSGNGISLAKIDKTGVTLYSDEEIENLVKKVTKKK
HHCCCCCCCEEEEEECCCCEEEECCHHHHHHHHHHHCCC
>Mature Secondary Structure
MISGSEYHKEYMKGTTTVGLICEDGVVLATDKRATMGNLIADKEAKKLYKIDDYIAMTIA
CCCCHHHHHHHHCCCCEEEEEECCCEEEEECCCCHHHHHHHCHHHHHHHHHCCEEEEEEE
GSVGDAQSLIRLLSAEAKIYKMRTGNNMTPLSCTTLTSNVLHGNRHYPLLTQLIIGGYDL
CCCCCHHHHHHHHHCCCEEEEEECCCCCCCEEHHHHHHHHHCCCCCCHHHHHHHHCCEEE
INGPKLFSLDPVGGINEESSFTATGSGSPTAYGVLEAEYKSEINIEKGLLIAVKALISAM
CCCCEEEEECCCCCCCCCCCEEECCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHH
QRDAYSGNGISLAKIDKTGVTLYSDEEIENLVKKVTKKK
HHCCCCCCCEEEEEECCCCEEEECCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA