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The map label for this gene is 150400120

Identifier: 150400120

GI number: 150400120

Start: 1408120

End: 1409268

Strand: Reverse

Name: 150400120

Synonym: Mevan_1378

Alternate gene names: NA

Gene position: 1409268-1408120 (Counterclockwise)

Preceding gene: 150400121

Following gene: 150400119

Centisome position: 81.93

GC content: 36.73

Gene sequence:

>1149_bases
ATGAAACAGATGGATACTGAAAAGCTTTTGATGATTCCTGGCCCAACTGTCGTTCCGACCAGGGTATTAAACGTAATGGC
ATTACCAATTATAGGCCATAGAACAAAAGATTTTGGGGAACTTACGGAAGATACTGTTGACAAAATGAAGCAGGTATTTC
AAACTAAGAACGAATCATACATCGTTACAGGTTCAGGAACTGCTGTAATGGATATGGCAATTGCAAACACTGTTGATAAG
GGCGATAAAGTATTAAACATTGTAAACGGTGCTTTTGGAGATAGGTTTTATAAAATTTCATCAGTTTATAAGGCTGATGC
AATAAAGCTTGAAAACGAATGGGGAGATTTAGCTGACCCTAATGCAGTAAAAGAAATTTTAGATGAAAATGAAGATATTA
AAGCTGTAACAATAGTTCATAACGAAACTTCAAGCGGTGCTAAAAACCCTATTGAAGAAATTGGAAACGTCGTAAAAGAC
TATAACGCCCTATACATTGTAGACACCATTTCTTCACTTGGTGGGGACTATGTTCACGTTGATAAATTCAATATAGACAT
CTGTGTAACTGGCTCACAAAAGTGTATTGCAGCACCCCCCGGACTTTCTGCAATTTCAGTAAGTGAAAAAGCTTTTGAAG
TAGTTAATAAAACAGAAACAAAATCGTTCTACTTGGATTTAAAAGCGTACAAAAAATCATGGGATAAAAATAAAGAAACA
CCCTATACCCCATCTGTTTCATTAACTTACGGGTTAAACGAAGCTCTTGAAATGGTTTTAGAAGAAGGCCTTGAAAAGAG
ATTTGAAAGACATGAAAAACTTGCAAAAGCTACCAGAGCAGGTTTAGAAGCTATGGGAATGGAATTATTTGCAAAAGAAA
AGGCACGGTCAGTTACGGTAACATCTGCAAAGTATCCAGAAGGTGTAGATGACAAGAAATTTAGGGGATTACTTGCAGAA
AAATATAACATAAGAGTTGCTGGCGGTCAAGCGGACTTAACTGGAAAGATTTTCAGAGTAGGCCATATGGGTTCAGCGAA
AGAATACCATGTTTTAGGAACTCTTGCTGCAATTGAACTTGCATTTGAAGAACTTGGAATAAATGCAGACGGTGGAGTGT
CTGCTGCAAAAGAAATGCTTTTAAAATAA

Upstream 100 bases:

>100_bases
TTAAAAACTCCTGTAAGAACAATGTATATATAATAGAAATATATATCAAATTCCGTCGATATAATTGATTATGATTAAAA
CATTATTATAGAGGGATTTC

Downstream 100 bases:

>100_bases
AAACTTACTTTAACTATGTTTTATAAATATTTATAAAACGTCTAATAGCCGTTTAGCTGATTTTATTTTATATATTAATC
TTATTTTTTTATATATCGAG

Product: Serine--pyruvate transaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 382; Mature: 382

Protein sequence:

>382_residues
MKQMDTEKLLMIPGPTVVPTRVLNVMALPIIGHRTKDFGELTEDTVDKMKQVFQTKNESYIVTGSGTAVMDMAIANTVDK
GDKVLNIVNGAFGDRFYKISSVYKADAIKLENEWGDLADPNAVKEILDENEDIKAVTIVHNETSSGAKNPIEEIGNVVKD
YNALYIVDTISSLGGDYVHVDKFNIDICVTGSQKCIAAPPGLSAISVSEKAFEVVNKTETKSFYLDLKAYKKSWDKNKET
PYTPSVSLTYGLNEALEMVLEEGLEKRFERHEKLAKATRAGLEAMGMELFAKEKARSVTVTSAKYPEGVDDKKFRGLLAE
KYNIRVAGGQADLTGKIFRVGHMGSAKEYHVLGTLAAIELAFEELGINADGGVSAAKEMLLK

Sequences:

>Translated_382_residues
MKQMDTEKLLMIPGPTVVPTRVLNVMALPIIGHRTKDFGELTEDTVDKMKQVFQTKNESYIVTGSGTAVMDMAIANTVDK
GDKVLNIVNGAFGDRFYKISSVYKADAIKLENEWGDLADPNAVKEILDENEDIKAVTIVHNETSSGAKNPIEEIGNVVKD
YNALYIVDTISSLGGDYVHVDKFNIDICVTGSQKCIAAPPGLSAISVSEKAFEVVNKTETKSFYLDLKAYKKSWDKNKET
PYTPSVSLTYGLNEALEMVLEEGLEKRFERHEKLAKATRAGLEAMGMELFAKEKARSVTVTSAKYPEGVDDKKFRGLLAE
KYNIRVAGGQADLTGKIFRVGHMGSAKEYHVLGTLAAIELAFEELGINADGGVSAAKEMLLK
>Mature_382_residues
MKQMDTEKLLMIPGPTVVPTRVLNVMALPIIGHRTKDFGELTEDTVDKMKQVFQTKNESYIVTGSGTAVMDMAIANTVDK
GDKVLNIVNGAFGDRFYKISSVYKADAIKLENEWGDLADPNAVKEILDENEDIKAVTIVHNETSSGAKNPIEEIGNVVKD
YNALYIVDTISSLGGDYVHVDKFNIDICVTGSQKCIAAPPGLSAISVSEKAFEVVNKTETKSFYLDLKAYKKSWDKNKET
PYTPSVSLTYGLNEALEMVLEEGLEKRFERHEKLAKATRAGLEAMGMELFAKEKARSVTVTSAKYPEGVDDKKFRGLLAE
KYNIRVAGGQADLTGKIFRVGHMGSAKEYHVLGTLAAIELAFEELGINADGGVSAAKEMLLK

Specific function: Unknown

COG id: COG0075

COG function: function code E; Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4557289, Length=345, Percent_Identity=32.463768115942, Blast_Score=199, Evalue=5e-51,
Organism=Caenorhabditis elegans, GI17536281, Length=346, Percent_Identity=30.9248554913295, Blast_Score=165, Evalue=3e-41,
Organism=Saccharomyces cerevisiae, GI6321079, Length=364, Percent_Identity=26.6483516483516, Blast_Score=118, Evalue=1e-27,
Organism=Drosophila melanogaster, GI17530823, Length=346, Percent_Identity=32.0809248554913, Blast_Score=187, Evalue=7e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: 2.6.1.-

Molecular weight: Translated: 41849; Mature: 41849

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQMDTEKLLMIPGPTVVPTRVLNVMALPIIGHRTKDFGELTEDTVDKMKQVFQTKNESY
CCCCCCCCEEEECCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCE
IVTGSGTAVMDMAIANTVDKGDKVLNIVNGAFGDRFYKISSVYKADAIKLENEWGDLADP
EEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHEEEECCCCCCCCC
NAVKEILDENEDIKAVTIVHNETSSGAKNPIEEIGNVVKDYNALYIVDTISSLGGDYVHV
HHHHHHHCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHCCCEEEEEEHHHCCCCEEEE
DKFNIDICVTGSQKCIAAPPGLSAISVSEKAFEVVNKTETKSFYLDLKAYKKSWDKNKET
EEEEEEEEEECCCCEEECCCCCCEEEHHHHHHHHHHCCCCCEEEEEHHHHHHHHCCCCCC
PYTPSVSLTYGLNEALEMVLEEGLEKRFERHEKLAKATRAGLEAMGMELFAKEKARSVTV
CCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEE
TSAKYPEGVDDKKFRGLLAEKYNIRVAGGQADLTGKIFRVGHMGSAKEYHVLGTLAAIEL
ECCCCCCCCCCHHHHHHHHHCEEEEEECCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHH
AFEELGINADGGVSAAKEMLLK
HHHHHCCCCCCCHHHHHHHHCC
>Mature Secondary Structure
MKQMDTEKLLMIPGPTVVPTRVLNVMALPIIGHRTKDFGELTEDTVDKMKQVFQTKNESY
CCCCCCCCEEEECCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCE
IVTGSGTAVMDMAIANTVDKGDKVLNIVNGAFGDRFYKISSVYKADAIKLENEWGDLADP
EEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHEEEECCCCCCCCC
NAVKEILDENEDIKAVTIVHNETSSGAKNPIEEIGNVVKDYNALYIVDTISSLGGDYVHV
HHHHHHHCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHCCCEEEEEEHHHCCCCEEEE
DKFNIDICVTGSQKCIAAPPGLSAISVSEKAFEVVNKTETKSFYLDLKAYKKSWDKNKET
EEEEEEEEEECCCCEEECCCCCCEEEHHHHHHHHHHCCCCCEEEEEHHHHHHHHCCCCCC
PYTPSVSLTYGLNEALEMVLEEGLEKRFERHEKLAKATRAGLEAMGMELFAKEKARSVTV
CCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEE
TSAKYPEGVDDKKFRGLLAEKYNIRVAGGQADLTGKIFRVGHMGSAKEYHVLGTLAAIEL
ECCCCCCCCCCHHHHHHHHHCEEEEEECCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHH
AFEELGINADGGVSAAKEMLLK
HHHHHCCCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]