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The map label for this gene is 150399642

Identifier: 150399642

GI number: 150399642

Start: 912179

End: 913750

Strand: Reverse

Name: 150399642

Synonym: Mevan_0892

Alternate gene names: NA

Gene position: 913750-912179 (Counterclockwise)

Preceding gene: 150399649

Following gene: 150399639

Centisome position: 53.12

GC content: 27.99

Gene sequence:

>1572_bases
ATGAAAATACTGATTATAACTGGAAAACAGGCTTTAAACAAAATAAATCTTTCGGTAAAAAAGTACGATTTTGTTGATGT
TTACAAAGCTAATGTATCAATTGCTGCATTTTTAACGCCTAAAATGATAATAAAAGAAATAAAAAATATCGAAAAATCGA
AAAACAAAAAATTATCTGAAATTTATGATTTTGTACTTGTAACTGGGCTTATAAGGCACGACTTAGAAGAAGTATTTCAA
GAAACAGGAATTAAGTGTTTTAAATCCACAAGGGAAGCTTCAGATATTTCTATATTACTAAAACACCTAAAAAATATTGA
ACTTTCAACAACTGAGTACGCAGACTCTAAAATTATGAAGTTCGTAAAAGAAAATGCTGAAAGAGAATTGGATTATGCAG
AAAAACTTCCATTAAATGAGGGAAATATAAAAATTGGAAAGTTAAAAGTAGGGGATAACTATCCTATGAGGGTTCTTGGG
GAAATTGTTCATGTACCGTGGCTAAAAGAAAAAGAACTGGAAGAAAAGATAAACTACTATATCGATTCTGGAGTAGATAT
GATAGATTTAGGAATGGTTAGTAATGAAAATCATTCAAAAAATTTAAAAGATATATTAAAAAATGTAAAAGATTTAACGG
ATAAACCAATAAGTGTAGATACATTAAACACTAAAGAGTTAGTTGAGGCCATAAAACTCGATGTAGACATGGTTTTAAGT
GTAGATTCAGGAAATTTTCAAGAAATATGCCCTCATTTAATTGAAAGTGAAACTACATCTGTAGTCCTCCCAACAAACTA
CAAAAAAAATGAAGTTCCAGAAACAATCAATGAAAAAATAATTAATCTGGAAAAAATAATTGAAAAATTCAAAGAAAATG
ATTTAAAAGTTGTTATGGATCCAATTTTAGAACCGATAAATAATAGTGGATGCAACTTTACCCAAAGTGTTATTGCATGC
TATGAACTTAAAAAAAGAAATAATATTCCAATGTTTTTTGGAATTGGGAATGTGACAGAACTTTTTGATGTCGATAGTAA
CGGCGTAAATGCAGTACTTTCTGCAATCAGCCAAGAAATTGGCGGAAATATTTTATTTACTCCTGAAGCTTCTTCAAAAT
GTAAATTTTCGATAAAAGAATTAAAAATAGCATCAAAAATGATTTACCTATCTAAAAAGAGAAATTCTCTTCCAAAAGAC
GTTGGATTTGATTTGATAAATTATAAAGATAAGAAATTTGATGAAGATTTTGAAGTTGAGGATTTAAATATACTTTCTGC
AAAAGAAAATCAAAATCAGGTTTTAGATAAGGGGAGCTTTAGAATTAAAGTAGATAGGAAAAACAATAAAATAATTGCAA
CATACTATCGATATAATGAACCAAAACTAATTATTTCGGGAAACACTCCAAAAGAAATATATGAAACCGCAATACGTGAA
AATTTAATTACAAAAATGGATCATGCAGCATACTTTGGAAAAGAGCTTCAAAATGCGTACAATGCTATTAAAATTGGTAA
AATGTACAACCAAGATTTTGAATTATTTTATAACGAATTTTGGAATGAATAA

Upstream 100 bases:

>100_bases
ATATACCAAGTACTGATTTTTAAGATTATTTGTAATTTGAAAAATATTTAAGACCTATATTTAAAAATCTCTCAAAAAAA
TCCTGATTTTTGGTGAGTTA

Downstream 100 bases:

>100_bases
TAACTTAAATAAAAAAATTCAAAAATTTTTGATTTGTTTTAAAAATAAAAAATATTGGATTATTCAACCAACAATCTTGC
AGTTTGTGGTGAGTATCTCC

Product: dihydropteroate synthase-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 523; Mature: 523

Protein sequence:

>523_residues
MKILIITGKQALNKINLSVKKYDFVDVYKANVSIAAFLTPKMIIKEIKNIEKSKNKKLSEIYDFVLVTGLIRHDLEEVFQ
ETGIKCFKSTREASDISILLKHLKNIELSTTEYADSKIMKFVKENAERELDYAEKLPLNEGNIKIGKLKVGDNYPMRVLG
EIVHVPWLKEKELEEKINYYIDSGVDMIDLGMVSNENHSKNLKDILKNVKDLTDKPISVDTLNTKELVEAIKLDVDMVLS
VDSGNFQEICPHLIESETTSVVLPTNYKKNEVPETINEKIINLEKIIEKFKENDLKVVMDPILEPINNSGCNFTQSVIAC
YELKKRNNIPMFFGIGNVTELFDVDSNGVNAVLSAISQEIGGNILFTPEASSKCKFSIKELKIASKMIYLSKKRNSLPKD
VGFDLINYKDKKFDEDFEVEDLNILSAKENQNQVLDKGSFRIKVDRKNNKIIATYYRYNEPKLIISGNTPKEIYETAIRE
NLITKMDHAAYFGKELQNAYNAIKIGKMYNQDFELFYNEFWNE

Sequences:

>Translated_523_residues
MKILIITGKQALNKINLSVKKYDFVDVYKANVSIAAFLTPKMIIKEIKNIEKSKNKKLSEIYDFVLVTGLIRHDLEEVFQ
ETGIKCFKSTREASDISILLKHLKNIELSTTEYADSKIMKFVKENAERELDYAEKLPLNEGNIKIGKLKVGDNYPMRVLG
EIVHVPWLKEKELEEKINYYIDSGVDMIDLGMVSNENHSKNLKDILKNVKDLTDKPISVDTLNTKELVEAIKLDVDMVLS
VDSGNFQEICPHLIESETTSVVLPTNYKKNEVPETINEKIINLEKIIEKFKENDLKVVMDPILEPINNSGCNFTQSVIAC
YELKKRNNIPMFFGIGNVTELFDVDSNGVNAVLSAISQEIGGNILFTPEASSKCKFSIKELKIASKMIYLSKKRNSLPKD
VGFDLINYKDKKFDEDFEVEDLNILSAKENQNQVLDKGSFRIKVDRKNNKIIATYYRYNEPKLIISGNTPKEIYETAIRE
NLITKMDHAAYFGKELQNAYNAIKIGKMYNQDFELFYNEFWNE
>Mature_523_residues
MKILIITGKQALNKINLSVKKYDFVDVYKANVSIAAFLTPKMIIKEIKNIEKSKNKKLSEIYDFVLVTGLIRHDLEEVFQ
ETGIKCFKSTREASDISILLKHLKNIELSTTEYADSKIMKFVKENAERELDYAEKLPLNEGNIKIGKLKVGDNYPMRVLG
EIVHVPWLKEKELEEKINYYIDSGVDMIDLGMVSNENHSKNLKDILKNVKDLTDKPISVDTLNTKELVEAIKLDVDMVLS
VDSGNFQEICPHLIESETTSVVLPTNYKKNEVPETINEKIINLEKIIEKFKENDLKVVMDPILEPINNSGCNFTQSVIAC
YELKKRNNIPMFFGIGNVTELFDVDSNGVNAVLSAISQEIGGNILFTPEASSKCKFSIKELKIASKMIYLSKKRNSLPKD
VGFDLINYKDKKFDEDFEVEDLNILSAKENQNQVLDKGSFRIKVDRKNNKIIATYYRYNEPKLIISGNTPKEIYETAIRE
NLITKMDHAAYFGKELQNAYNAIKIGKMYNQDFELFYNEFWNE

Specific function: Unknown. Does not possess dihydropteroate synthase (DHPS) activity since it does not catalyze the condensation of 6- hydroxymethyl-7,8-dihydropterin pyrophosphate (DHPP) and 4- aminobenzoate to form 7,8-dihydropteroate [H]

COG id: COG0294

COG function: function code H; Dihydropteroate synthase and related enzymes

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 pterin-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005236
- InterPro:   IPR011005
- InterPro:   IPR000489 [H]

Pfam domain/function: PF00809 Pterin_bind [H]

EC number: NA

Molecular weight: Translated: 59993; Mature: 59993

Theoretical pI: Translated: 5.87; Mature: 5.87

Prosite motif: PS50972 PTERIN_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKILIITGKQALNKINLSVKKYDFVDVYKANVSIAAFLTPKMIIKEIKNIEKSKNKKLSE
CEEEEEECHHHHHHHCCEEEEECEEEEEECCEEEEEHHCHHHHHHHHHHHHHHHCCHHHH
IYDFVLVTGLIRHDLEEVFQETGIKCFKSTREASDISILLKHLKNIELSTTEYADSKIMK
HHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHHHH
FVKENAERELDYAEKLPLNEGNIKIGKLKVGDNYPMRVLGEIVHVPWLKEKELEEKINYY
HHHHHHHHHCCHHHHCCCCCCCEEEEEEEECCCCCHHHHHHHHHCCCCCHHHHHHHHHHH
IDSGVDMIDLGMVSNENHSKNLKDILKNVKDLTDKPISVDTLNTKELVEAIKLDVDMVLS
HCCCCCEEEECEECCCCCCCHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHCCEEEEEE
VDSGNFQEICPHLIESETTSVVLPTNYKKNEVPETINEKIINLEKIIEKFKENDLKVVMD
ECCCCHHHHHHHHHCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEHHH
PILEPINNSGCNFTQSVIACYELKKRNNIPMFFGIGNVTELFDVDSNGVNAVLSAISQEI
HHHHCCCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCHHHHEECCCCCHHHHHHHHHHHH
GGNILFTPEASSKCKFSIKELKIASKMIYLSKKRNSLPKDVGFDLINYKDKKFDEDFEVE
CCCEEECCCCCCCCEEHHHHHHHHHHHHHHHHHCCCCCHHHCCHHHCCCCCCCCCCCCCC
DLNILSAKENQNQVLDKGSFRIKVDRKNNKIIATYYRYNEPKLIISGNTPKEIYETAIRE
CCEEEECCCCCHHHHCCCCEEEEEECCCCCEEEEEEEECCCEEEEECCCHHHHHHHHHHH
NLITKMDHAAYFGKELQNAYNAIKIGKMYNQDFELFYNEFWNE
HHHHHHHHHHHHHHHHHHHHHHEEHHHHHCCHHHHHHHHHCCC
>Mature Secondary Structure
MKILIITGKQALNKINLSVKKYDFVDVYKANVSIAAFLTPKMIIKEIKNIEKSKNKKLSE
CEEEEEECHHHHHHHCCEEEEECEEEEEECCEEEEEHHCHHHHHHHHHHHHHHHCCHHHH
IYDFVLVTGLIRHDLEEVFQETGIKCFKSTREASDISILLKHLKNIELSTTEYADSKIMK
HHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHHHH
FVKENAERELDYAEKLPLNEGNIKIGKLKVGDNYPMRVLGEIVHVPWLKEKELEEKINYY
HHHHHHHHHCCHHHHCCCCCCCEEEEEEEECCCCCHHHHHHHHHCCCCCHHHHHHHHHHH
IDSGVDMIDLGMVSNENHSKNLKDILKNVKDLTDKPISVDTLNTKELVEAIKLDVDMVLS
HCCCCCEEEECEECCCCCCCHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHCCEEEEEE
VDSGNFQEICPHLIESETTSVVLPTNYKKNEVPETINEKIINLEKIIEKFKENDLKVVMD
ECCCCHHHHHHHHHCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEHHH
PILEPINNSGCNFTQSVIACYELKKRNNIPMFFGIGNVTELFDVDSNGVNAVLSAISQEI
HHHHCCCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCHHHHEECCCCCHHHHHHHHHHHH
GGNILFTPEASSKCKFSIKELKIASKMIYLSKKRNSLPKDVGFDLINYKDKKFDEDFEVE
CCCEEECCCCCCCCEEHHHHHHHHHHHHHHHHHCCCCCHHHCCHHHCCCCCCCCCCCCCC
DLNILSAKENQNQVLDKGSFRIKVDRKNNKIIATYYRYNEPKLIISGNTPKEIYETAIRE
CCEEEECCCCCHHHHCCCCEEEEEECCCCCEEEEEEEECCCEEEEECCCHHHHHHHHHHH
NLITKMDHAAYFGKELQNAYNAIKIGKMYNQDFELFYNEFWNE
HHHHHHHHHHHHHHHHHHHHHHEEHHHHHCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]