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The map label for this gene is rpiA

Identifier: 150399257

GI number: 150399257

Start: 552342

End: 553061

Strand: Reverse

Name: rpiA

Synonym: Mevan_0505

Alternate gene names: 150399257

Gene position: 553061-552342 (Counterclockwise)

Preceding gene: 150399258

Following gene: 150399256

Centisome position: 32.15

GC content: 34.31

Gene sequence:

>720_bases
ATGGCAAAACCTAAAAAATCTGACGAAGAGGTATCAATAGATTCCGATTCACTAAAGATAAAAGTTGCAAAAGAAGCTGC
AAAACTTATAAAAGATGAGATGGTTGTAGGACTTGGTTCTGGTTCAACTGCAAATTTATTCATTCAAGAACTTGGAAAAC
GAGTTATTGAAGAAGAACTTTATATTTATGGCGTTCCAACGTCATTTGACTCAAGAATGATGGCAAATCAGTCTGGAATT
CCATTAATTTCACTGGATCAATGTGGTGAAATTGATATAGCAATAGATGGGGCAGACGAAATTGATAAAAAGACTTTTTC
ATTAATAAAGGGCGGGGGTGGATGCCATACAATGGAAAAAATTGTTGATTATTATGCAAAAGAGTTTGTAGTTTTGGCGG
ATGAAAGTAAAATGGTTGATTCACTTGGTGAAAACACCCCTGTTCCTTTAGAAGTAATCCCTTTTTCGTATTCAACTGTT
TTAAGTAAACTTTTAAAAATTAATGCGGCACCTGCAATAAGGTCAGGTTCTGGAAAGATGGGCCCCGTAATTACTGACAA
TGGAAACATGATAATAGATGTATTTATAAACATTGAAGATGCAGAAGAAACCGAAACAATGCTAAACAGTATTCCGGGAG
TTTTGGAAAACGGGATATTTACAAAGTGCGATAAAGTACTTATTGGAACTTCCAAAAAAGTTGAAGTTTTAAAGAAATAA

Upstream 100 bases:

>100_bases
TATAAGATTTAATAAAAGTCATAATAGAAATTATAATCATATACTATTTAATAAACTATTTTTTCATTAAAACTGTTTTT
TAGAAATTTCTGGTGATTTT

Downstream 100 bases:

>100_bases
TTTAAGACTTTTTTTCATTAAAAAACTCTTTATTTTTCATTTAACCTCAATCTTTAAATATGACATGCATTAATCATATT
ATGCAATTAGTTGAATTTAC

Product: ribose-5-phosphate isomerase A

Products: NA

Alternate protein names: Phosphoriboisomerase A; PRI

Number of amino acids: Translated: 239; Mature: 238

Protein sequence:

>239_residues
MAKPKKSDEEVSIDSDSLKIKVAKEAAKLIKDEMVVGLGSGSTANLFIQELGKRVIEEELYIYGVPTSFDSRMMANQSGI
PLISLDQCGEIDIAIDGADEIDKKTFSLIKGGGGCHTMEKIVDYYAKEFVVLADESKMVDSLGENTPVPLEVIPFSYSTV
LSKLLKINAAPAIRSGSGKMGPVITDNGNMIIDVFINIEDAEETETMLNSIPGVLENGIFTKCDKVLIGTSKKVEVLKK

Sequences:

>Translated_239_residues
MAKPKKSDEEVSIDSDSLKIKVAKEAAKLIKDEMVVGLGSGSTANLFIQELGKRVIEEELYIYGVPTSFDSRMMANQSGI
PLISLDQCGEIDIAIDGADEIDKKTFSLIKGGGGCHTMEKIVDYYAKEFVVLADESKMVDSLGENTPVPLEVIPFSYSTV
LSKLLKINAAPAIRSGSGKMGPVITDNGNMIIDVFINIEDAEETETMLNSIPGVLENGIFTKCDKVLIGTSKKVEVLKK
>Mature_238_residues
AKPKKSDEEVSIDSDSLKIKVAKEAAKLIKDEMVVGLGSGSTANLFIQELGKRVIEEELYIYGVPTSFDSRMMANQSGIP
LISLDQCGEIDIAIDGADEIDKKTFSLIKGGGGCHTMEKIVDYYAKEFVVLADESKMVDSLGENTPVPLEVIPFSYSTVL
SKLLKINAAPAIRSGSGKMGPVITDNGNMIIDVFINIEDAEETETMLNSIPGVLENGIFTKCDKVLIGTSKKVEVLKK

Specific function: Nonoxidative branch of the pentose phosphate pathway. [C]

COG id: COG0120

COG function: function code G; Ribose 5-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribose 5-phosphate isomerase family

Homologues:

Organism=Homo sapiens, GI94536842, Length=216, Percent_Identity=41.6666666666667, Blast_Score=150, Evalue=8e-37,
Organism=Escherichia coli, GI1789280, Length=229, Percent_Identity=38.8646288209607, Blast_Score=128, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI17551758, Length=212, Percent_Identity=37.7358490566038, Blast_Score=129, Evalue=1e-30,
Organism=Saccharomyces cerevisiae, GI6324669, Length=222, Percent_Identity=38.2882882882883, Blast_Score=123, Evalue=3e-29,
Organism=Drosophila melanogaster, GI281364072, Length=217, Percent_Identity=40.0921658986175, Blast_Score=126, Evalue=1e-29,

Paralogues:

None

Copy number: 740 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): RPIA_METVS (A6UPJ0)

Other databases:

- EMBL:   CP000742
- RefSeq:   YP_001323024.1
- ProteinModelPortal:   A6UPJ0
- SMR:   A6UPJ0
- STRING:   A6UPJ0
- GeneID:   5325659
- GenomeReviews:   CP000742_GR
- KEGG:   mvn:Mevan_0505
- eggNOG:   arNOG07879
- HOGENOM:   HBG515603
- OMA:   VFDLNSV
- ProtClustDB:   PRK00702
- HAMAP:   MF_00170
- InterPro:   IPR014036
- InterPro:   IPR004788
- InterPro:   IPR020672
- PANTHER:   PTHR11934
- TIGRFAMs:   TIGR00021

Pfam domain/function: PF00455 DeoR; PF06026 Rib_5-P_isom_A

EC number: =5.3.1.6

Molecular weight: Translated: 25842; Mature: 25711

Theoretical pI: Translated: 4.47; Mature: 4.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKPKKSDEEVSIDSDSLKIKVAKEAAKLIKDEMVVGLGSGSTANLFIQELGKRVIEEEL
CCCCCCCCCCEEECCCCEEEEEHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHCCE
YIYGVPTSFDSRMMANQSGIPLISLDQCGEIDIAIDGADEIDKKTFSLIKGGGGCHTMEK
EEEECCCCCCHHHHCCCCCCCEEEECCCCCEEEEECCCHHHHHHHHHHHCCCCCHHHHHH
IVDYYAKEFVVLADESKMVDSLGENTPVPLEVIPFSYSTVLSKLLKINAAPAIRSGSGKM
HHHHHHHCEEEEECCHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHCCCCCCEECCCCCC
GPVITDNGNMIIDVFINIEDAEETETMLNSIPGVLENGIFTKCDKVLIGTSKKVEVLKK
CCEEECCCCEEEEEEEECCCCHHHHHHHHHCCHHHHCCCHHHCCCEEECCCCHHHHHCC
>Mature Secondary Structure 
AKPKKSDEEVSIDSDSLKIKVAKEAAKLIKDEMVVGLGSGSTANLFIQELGKRVIEEEL
CCCCCCCCCEEECCCCEEEEEHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHCCE
YIYGVPTSFDSRMMANQSGIPLISLDQCGEIDIAIDGADEIDKKTFSLIKGGGGCHTMEK
EEEECCCCCCHHHHCCCCCCCEEEECCCCCEEEEECCCHHHHHHHHHHHCCCCCHHHHHH
IVDYYAKEFVVLADESKMVDSLGENTPVPLEVIPFSYSTVLSKLLKINAAPAIRSGSGKM
HHHHHHHCEEEEECCHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHCCCCCCEECCCCCC
GPVITDNGNMIIDVFINIEDAEETETMLNSIPGVLENGIFTKCDKVLIGTSKKVEVLKK
CCEEECCCCEEEEEEEECCCCHHHHHHHHHCCHHHHCCCHHHCCCEEECCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA