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The map label for this gene is fwdB [H]

Identifier: 150398826

GI number: 150398826

Start: 65270

End: 66574

Strand: Reverse

Name: fwdB [H]

Synonym: Mevan_0067

Alternate gene names: 150398826

Gene position: 66574-65270 (Counterclockwise)

Preceding gene: 150398827

Following gene: 150398824

Centisome position: 3.87

GC content: 35.79

Gene sequence:

>1305_bases
ATGGAAGTTATTAAAAATATAGTCTGCCCATTTTGTGGAACACTTTGTGACGATATTGAGTGTCATGTAGATCATGGGCA
TATTGTAAAAACTAGAAATGCTTGTAGGATTGGACATAGTAAATTTACACACCGAGAGGGTGCTGTAAGATATACTGAAC
CGTTATTTCGGGAAAATAAAAAAGATGAATTCAAAGTAATTGATTGGGACACTGCAATAGAAAAAACTGCCGAAATATTG
GTAAATGCTAAAAAACCATTAATTTATGGATTTTCTGCAACTGAATGCCATGCACATATCGAAGGAATGAAGTTGGCAGA
AAAAATAAGGGGCTTAGTAAGTAATACTGCTGAAGTATGTCACGGACCAAGTGTTTGGGCACTTCAAGATGTTGGATACC
CAATATGTACGCTTGGAGAAGTTAAAAATCGAGCAGATGTAGTAATTTACTGGGGTTCAAATCCAATGCACGCACACCCA
AGACACATGAGTAGATACGGAGTATTCGCAAGAGGATTTTTCAGAGAACGAGGGAGAAAAGATAGAACCGTAATAGTTAT
AGATCCAAGAGAAACCGACACTGCAAAATTAGCAGATATTCATTTAAAAGTGGATCCTCATAAAGATTATGAACTTGTTT
CTGCATTAAGGGCCTCATTGAAAGGCTTTGAACTTAAATCCGATATAATTGCAGGAATTCCAAAAGAAACTATTGAAAAA
GCAGTAGAAGTTTTAAAAAATGCCCAATTTGGAGAACTGTTCTTTGCAATGGGGGTAACTCAGACTAAAGGGAAACACAG
GAATATTGATACAGCAATACAATTAATAGTTGATTTAAATGCATTTACTAAATTTACATTAATCCCGATGAGGGGACACT
ATAATGTAAATGGATTTAATCAAGTTTGTACCTGGATTAGTGGATTTCCACTCTGTGTGGACTATTCAAAAGGTTTTCCA
GAATTTAACCCTGGAGAAACAGGGGTTACAGACTCATTGATGAGAAATGAAGCAGATGCAATGCTAAATATCGCATCAGA
CCCTGGAGCGCATTTTCCTCAAAAAGCAGTTAAAAGAATGTCTGAAATTCCACTTATATGTATTGACCCACATGAAACTC
CAACATCAGTTCTTGCAAATATTATTCTTCCGCCAACAATTGCAGGCATTGAAGATACAGGGACTGCTTACCGAATGGAT
GGAGTTCCACTAGAACTTAAAAAAGTTATAAATCCACCCAATGGAACACTTCCTGATAGAGAAATATTAAAAAAGATATT
TAAAAAGGTCGAAGAATTAATTTAA

Upstream 100 bases:

>100_bases
CAAATTTATGGGCAGATTGAAGGAGTGTTTAAAGACTCATACTAATCCTATTTCCATTTTTACTATTTTTAAATTGGATG
ATCTTTAACTGGTGGTATTT

Downstream 100 bases:

>100_bases
TAAATATTTAATTTTTTATCAAAGCACTTATTTCTTGAATTAAACTGATTAAAAATATTAAAAACAGTTAATTTGAATTT
TTTAATGCTACAATATCATT

Product: molybdopterin oxidoreductase

Products: NA

Alternate protein names: Tungsten-containing formylmethanofuran dehydrogenase II subunit B [H]

Number of amino acids: Translated: 434; Mature: 434

Protein sequence:

>434_residues
MEVIKNIVCPFCGTLCDDIECHVDHGHIVKTRNACRIGHSKFTHREGAVRYTEPLFRENKKDEFKVIDWDTAIEKTAEIL
VNAKKPLIYGFSATECHAHIEGMKLAEKIRGLVSNTAEVCHGPSVWALQDVGYPICTLGEVKNRADVVIYWGSNPMHAHP
RHMSRYGVFARGFFRERGRKDRTVIVIDPRETDTAKLADIHLKVDPHKDYELVSALRASLKGFELKSDIIAGIPKETIEK
AVEVLKNAQFGELFFAMGVTQTKGKHRNIDTAIQLIVDLNAFTKFTLIPMRGHYNVNGFNQVCTWISGFPLCVDYSKGFP
EFNPGETGVTDSLMRNEADAMLNIASDPGAHFPQKAVKRMSEIPLICIDPHETPTSVLANIILPPTIAGIEDTGTAYRMD
GVPLELKKVINPPNGTLPDREILKKIFKKVEELI

Sequences:

>Translated_434_residues
MEVIKNIVCPFCGTLCDDIECHVDHGHIVKTRNACRIGHSKFTHREGAVRYTEPLFRENKKDEFKVIDWDTAIEKTAEIL
VNAKKPLIYGFSATECHAHIEGMKLAEKIRGLVSNTAEVCHGPSVWALQDVGYPICTLGEVKNRADVVIYWGSNPMHAHP
RHMSRYGVFARGFFRERGRKDRTVIVIDPRETDTAKLADIHLKVDPHKDYELVSALRASLKGFELKSDIIAGIPKETIEK
AVEVLKNAQFGELFFAMGVTQTKGKHRNIDTAIQLIVDLNAFTKFTLIPMRGHYNVNGFNQVCTWISGFPLCVDYSKGFP
EFNPGETGVTDSLMRNEADAMLNIASDPGAHFPQKAVKRMSEIPLICIDPHETPTSVLANIILPPTIAGIEDTGTAYRMD
GVPLELKKVINPPNGTLPDREILKKIFKKVEELI
>Mature_434_residues
MEVIKNIVCPFCGTLCDDIECHVDHGHIVKTRNACRIGHSKFTHREGAVRYTEPLFRENKKDEFKVIDWDTAIEKTAEIL
VNAKKPLIYGFSATECHAHIEGMKLAEKIRGLVSNTAEVCHGPSVWALQDVGYPICTLGEVKNRADVVIYWGSNPMHAHP
RHMSRYGVFARGFFRERGRKDRTVIVIDPRETDTAKLADIHLKVDPHKDYELVSALRASLKGFELKSDIIAGIPKETIEK
AVEVLKNAQFGELFFAMGVTQTKGKHRNIDTAIQLIVDLNAFTKFTLIPMRGHYNVNGFNQVCTWISGFPLCVDYSKGFP
EFNPGETGVTDSLMRNEADAMLNIASDPGAHFPQKAVKRMSEIPLICIDPHETPTSVLANIILPPTIAGIEDTGTAYRMD
GVPLELKKVINPPNGTLPDREILKKIFKKVEELI

Specific function: Catalyzes the reversible oxidation of CO(2) and methanofuran (MFR) to N-formylmethanofuran (CHO-MFR). This enzyme is oxygen-labile [H]

COG id: COG1029

COG function: function code C; Formylmethanofuran dehydrogenase subunit B

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fwdB family [H]

Homologues:

Organism=Escherichia coli, GI3868721, Length=510, Percent_Identity=23.7254901960784, Blast_Score=86, Evalue=5e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016457
- InterPro:   IPR006656 [H]

Pfam domain/function: PF00384 Molybdopterin [H]

EC number: =1.2.99.5 [H]

Molecular weight: Translated: 48569; Mature: 48569

Theoretical pI: Translated: 7.40; Mature: 7.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEVIKNIVCPFCGTLCDDIECHVDHGHIVKTRNACRIGHSKFTHREGAVRYTEPLFRENK
CCHHHHHHHHHHHHHHCCCEEEECCCCEEECCCHHHCCCCHHHCCCCCCCCCCHHHHCCC
KDEFKVIDWDTAIEKTAEILVNAKKPLIYGFSATECHAHIEGMKLAEKIRGLVSNTAEVC
CCCEEEEECHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HGPSVWALQDVGYPICTLGEVKNRADVVIYWGSNPMHAHPRHMSRYGVFARGFFRERGRK
CCCCEEEEHHCCCCEEEHHCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCC
DRTVIVIDPRETDTAKLADIHLKVDPHKDYELVSALRASLKGFELKSDIIAGIPKETIEK
CCEEEEECCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHCCCEEHHHHHHCCCHHHHHH
AVEVLKNAQFGELFFAMGVTQTKGKHRNIDTAIQLIVDLNAFTKFTLIPMRGHYNVNGFN
HHHHHHCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCCHH
QVCTWISGFPLCVDYSKGFPEFNPGETGVTDSLMRNEADAMLNIASDPGAHFPQKAVKRM
HHHHHHCCCCEEEECCCCCCCCCCCCCCCHHHHHHCCCHHEEEECCCCCCCCHHHHHHHH
SEIPLICIDPHETPTSVLANIILPPTIAGIEDTGTAYRMDGVPLELKKVINPPNGTLPDR
HHCCEEEECCCCCHHHHHHHHHCCCCCCCCCCCCCEEEECCCCHHHHHHCCCCCCCCCHH
EILKKIFKKVEELI
HHHHHHHHHHHHHC
>Mature Secondary Structure
MEVIKNIVCPFCGTLCDDIECHVDHGHIVKTRNACRIGHSKFTHREGAVRYTEPLFRENK
CCHHHHHHHHHHHHHHCCCEEEECCCCEEECCCHHHCCCCHHHCCCCCCCCCCHHHHCCC
KDEFKVIDWDTAIEKTAEILVNAKKPLIYGFSATECHAHIEGMKLAEKIRGLVSNTAEVC
CCCEEEEECHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HGPSVWALQDVGYPICTLGEVKNRADVVIYWGSNPMHAHPRHMSRYGVFARGFFRERGRK
CCCCEEEEHHCCCCEEEHHCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCC
DRTVIVIDPRETDTAKLADIHLKVDPHKDYELVSALRASLKGFELKSDIIAGIPKETIEK
CCEEEEECCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHCCCEEHHHHHHCCCHHHHHH
AVEVLKNAQFGELFFAMGVTQTKGKHRNIDTAIQLIVDLNAFTKFTLIPMRGHYNVNGFN
HHHHHHCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCCHH
QVCTWISGFPLCVDYSKGFPEFNPGETGVTDSLMRNEADAMLNIASDPGAHFPQKAVKRM
HHHHHHCCCCEEEECCCCCCCCCCCCCCCHHHHHHCCCHHEEEECCCCCCCCHHHHHHHH
SEIPLICIDPHETPTSVLANIILPPTIAGIEDTGTAYRMDGVPLELKKVINPPNGTLPDR
HHCCEEEECCCCCHHHHHHHHHCCCCCCCCCCCCCEEEECCCCHHHHHHCCCCCCCCCHH
EILKKIFKKVEELI
HHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]