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The map label for this gene is hdrA2 [H]

Identifier: 150398827

GI number: 150398827

Start: 66630

End: 68594

Strand: Reverse

Name: hdrA2 [H]

Synonym: Mevan_0068

Alternate gene names: 150398827

Gene position: 68594-66630 (Counterclockwise)

Preceding gene: 150398828

Following gene: 150398826

Centisome position: 3.99

GC content: 38.17

Gene sequence:

>1965_bases
ATGGAAGAACCAAAAATAGGAGTTTATGTCTGCCACTGCGGTGTAAACATTGGTGGCGTAGTTGATTGCGAAAATGTTGC
AAAAACTGCAGAAGGACTCAAAAACGTTGTAATTTCAAGAGAATATAAATACATGTGTGCAGATCCGGGACAAGAACTTA
TAAAGAAAGATATCAAAGAACTTGGATTAAATAGAGTAATTGTTGCTGCATGTTCCCCACGACTTCACGAACCAACATTT
AGACGATGTGTTGAAGAAGCAGGTTTAAACCCATTTTTGTTTGAATTTGCAAATATTCGTGAGCACTGTTCATGGGTACA
TATGAAAGAGAAAGAAAAAGCAACTGAAAAAGCAAACGATCTCGTTAGAATGGCGGTTGCAAAAGCAAGACAGTTAGACC
CATTAGACTACTTAACAGTACCGGTTACAAGAAGAGCACTTGTTATCGGTGCAGGGGTTGCAGGAATTCAGGCAGCACTT
GATTTAGGGGATTCTGGGTATGAAACCATTTTAGTTGAAAAAACTCCCTCAGTTGGAGGTAGAATGGCACAACTCGATAA
AGTATTTCCAACAAATGACTGTTCAATCTGTATTTTAGCTCCAAAAATGGTTGATGTTGCAAAACACCCAAACATTAAAC
TTTACTCCTATTCAGAAGTAAAAGATGTAAGCGGATACATTGGAAACTTTAAAGTAAAAATCGAGAAAAAACCAAGATAC
TTATCCGAAGAAAAATGTACCGGATGCGGTTCATGTGAAGAAGTCTGCCCAATAACCGTTCCAAATGAATTTGACATGGG
AATTGGAATGAGAAAGGCCATTTACAAACCATTCCCACAAGCAGTTCCTGCAAAATACACAATCGATAAAGAAAGCTGTA
TTGATTGTGGATTATGCGCAAAAGTTTGTGGCCCACAAGCTATTAATTACAATCAAAAACCAGAAATTATTGAAGCAGAA
ATTGGTACAATTATTTCTGCAATCGGTTATGACCCATACGACCCAACAGAAAAAGAAGAGTATGGTTATGGAAAAATTCC
AAACGTTATTACGTCAATGGAACTTGAAAGAATGATTAATGCGTCAGGCCCTACAATGGGGAAGGTAATCAGGCCAAGTG
ATGGTAAAAAACCAAAAAGGATTGCATTTATCCAGTGTGTTGGTTCAAGAGATGCAAAAATCGGTAAAAAGTATTGTTCA
AACGTATGCTGTATGTATGCAATGAAGAATTCACAGTTAATTAAAGAAAAATCCCCTGAAACTGAAATTGATATTTATTA
TATGGACATCCGGGCATTTAGTAAAGGTTATGAAGAGTTTTACGAAAGAAGCTCAAAACAATACGGAATTAAGTTTATTA
GGGGAAGACCTGCACAAGTTTTAGACAATCCTAAAACAGATAATCCAACAATAAGATCAGAAGACACGCTTTTAGGAGAA
ATCTTCGAAAATGACTACGATTTAGTGGTTCTTTCAGTAGGTATGGTTCCGTCAAAAAGTGCTGACGAAGTACAAAAATT
ACTCGGTGTTTCAAGAACAACTGATAGATTCTTCATGGAAGCCCACCCTAAATTAAAACCAGTTGATACTGCAACGGATG
GTGTCTATTTAGCAGGTGCGTGTCAGGGTCCAAAAGATATTCCTGCATCAGTTGCACAAGGTTCAGCAGCAGCTTCAAGA
GCAGCAATACCTCTTGCAAAAGGGGAAGTTCAGGTTGAACCAATAGTTGTAACACTTGATGAAGATGTTTGTGGTGCATG
CGGTATTTGTGTTCAACAGTGTCCATATGGCGCCCCAAGATTTGTTGAAAAAGATGGAAAACAGGCTTTAGAAGTTCTTT
CAGCATTGTGTAAGGGTTGCGGAACCTGTGCTGGAGGATGCCCTAGTGGGGCCCTTGAACAATCACACTTTAAAACAAAC
CAAATTTATGGGCAGATTGAAGGAGTGTTTAAAGACTCATACTAA

Upstream 100 bases:

>100_bases
CTTTAAATTAATTTTTAATAGGGCCACCTATTAGAAATATTAATATATACATTAATATATTTATTATGAATAACAGTTCA
GGCCAAATATTGGTGATATT

Downstream 100 bases:

>100_bases
TCCTATTTCCATTTTTACTATTTTTAAATTGGATGATCTTTAACTGGTGGTATTTATGGAAGTTATTAAAAATATAGTCT
GCCCATTTTGTGGAACACTT

Product: 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 654; Mature: 654

Protein sequence:

>654_residues
MEEPKIGVYVCHCGVNIGGVVDCENVAKTAEGLKNVVISREYKYMCADPGQELIKKDIKELGLNRVIVAACSPRLHEPTF
RRCVEEAGLNPFLFEFANIREHCSWVHMKEKEKATEKANDLVRMAVAKARQLDPLDYLTVPVTRRALVIGAGVAGIQAAL
DLGDSGYETILVEKTPSVGGRMAQLDKVFPTNDCSICILAPKMVDVAKHPNIKLYSYSEVKDVSGYIGNFKVKIEKKPRY
LSEEKCTGCGSCEEVCPITVPNEFDMGIGMRKAIYKPFPQAVPAKYTIDKESCIDCGLCAKVCGPQAINYNQKPEIIEAE
IGTIISAIGYDPYDPTEKEEYGYGKIPNVITSMELERMINASGPTMGKVIRPSDGKKPKRIAFIQCVGSRDAKIGKKYCS
NVCCMYAMKNSQLIKEKSPETEIDIYYMDIRAFSKGYEEFYERSSKQYGIKFIRGRPAQVLDNPKTDNPTIRSEDTLLGE
IFENDYDLVVLSVGMVPSKSADEVQKLLGVSRTTDRFFMEAHPKLKPVDTATDGVYLAGACQGPKDIPASVAQGSAAASR
AAIPLAKGEVQVEPIVVTLDEDVCGACGICVQQCPYGAPRFVEKDGKQALEVLSALCKGCGTCAGGCPSGALEQSHFKTN
QIYGQIEGVFKDSY

Sequences:

>Translated_654_residues
MEEPKIGVYVCHCGVNIGGVVDCENVAKTAEGLKNVVISREYKYMCADPGQELIKKDIKELGLNRVIVAACSPRLHEPTF
RRCVEEAGLNPFLFEFANIREHCSWVHMKEKEKATEKANDLVRMAVAKARQLDPLDYLTVPVTRRALVIGAGVAGIQAAL
DLGDSGYETILVEKTPSVGGRMAQLDKVFPTNDCSICILAPKMVDVAKHPNIKLYSYSEVKDVSGYIGNFKVKIEKKPRY
LSEEKCTGCGSCEEVCPITVPNEFDMGIGMRKAIYKPFPQAVPAKYTIDKESCIDCGLCAKVCGPQAINYNQKPEIIEAE
IGTIISAIGYDPYDPTEKEEYGYGKIPNVITSMELERMINASGPTMGKVIRPSDGKKPKRIAFIQCVGSRDAKIGKKYCS
NVCCMYAMKNSQLIKEKSPETEIDIYYMDIRAFSKGYEEFYERSSKQYGIKFIRGRPAQVLDNPKTDNPTIRSEDTLLGE
IFENDYDLVVLSVGMVPSKSADEVQKLLGVSRTTDRFFMEAHPKLKPVDTATDGVYLAGACQGPKDIPASVAQGSAAASR
AAIPLAKGEVQVEPIVVTLDEDVCGACGICVQQCPYGAPRFVEKDGKQALEVLSALCKGCGTCAGGCPSGALEQSHFKTN
QIYGQIEGVFKDSY
>Mature_654_residues
MEEPKIGVYVCHCGVNIGGVVDCENVAKTAEGLKNVVISREYKYMCADPGQELIKKDIKELGLNRVIVAACSPRLHEPTF
RRCVEEAGLNPFLFEFANIREHCSWVHMKEKEKATEKANDLVRMAVAKARQLDPLDYLTVPVTRRALVIGAGVAGIQAAL
DLGDSGYETILVEKTPSVGGRMAQLDKVFPTNDCSICILAPKMVDVAKHPNIKLYSYSEVKDVSGYIGNFKVKIEKKPRY
LSEEKCTGCGSCEEVCPITVPNEFDMGIGMRKAIYKPFPQAVPAKYTIDKESCIDCGLCAKVCGPQAINYNQKPEIIEAE
IGTIISAIGYDPYDPTEKEEYGYGKIPNVITSMELERMINASGPTMGKVIRPSDGKKPKRIAFIQCVGSRDAKIGKKYCS
NVCCMYAMKNSQLIKEKSPETEIDIYYMDIRAFSKGYEEFYERSSKQYGIKFIRGRPAQVLDNPKTDNPTIRSEDTLLGE
IFENDYDLVVLSVGMVPSKSADEVQKLLGVSRTTDRFFMEAHPKLKPVDTATDGVYLAGACQGPKDIPASVAQGSAAASR
AAIPLAKGEVQVEPIVVTLDEDVCGACGICVQQCPYGAPRFVEKDGKQALEVLSALCKGCGTCAGGCPSGALEQSHFKTN
QIYGQIEGVFKDSY

Specific function: Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). May act as the catalytic subunit [H]

COG id: COG1148

COG function: function code C; Heterodisulfide reductase, subunit A and related polyferredoxins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 4 4Fe-4S ferredoxin-type domains [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001450
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR003953
- InterPro:   IPR012285 [H]

Pfam domain/function: PF00890 FAD_binding_2; PF00037 Fer4 [H]

EC number: =1.8.98.1 [H]

Molecular weight: Translated: 71628; Mature: 71628

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
7.0 %Cys+Met (Translated Protein)
4.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
7.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEEPKIGVYVCHCGVNIGGVVDCENVAKTAEGLKNVVISREYKYMCADPGQELIKKDIKE
CCCCCEEEEEEEECCCCCCEEEHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHH
LGLNRVIVAACSPRLHEPTFRRCVEEAGLNPFLFEFANIREHCSWVHMKEKEKATEKAND
CCCCEEEEEECCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVRMAVAKARQLDPLDYLTVPVTRRALVIGAGVAGIQAALDLGDSGYETILVEKTPSVGG
HHHHHHHHHHCCCCCCEEECCCCCEEEEEECCHHHHHHHHHCCCCCCEEEEEECCCCCCC
RMAQLDKVFPTNDCSICILAPKMVDVAKHPNIKLYSYSEVKDVSGYIGNFKVKIEKKPRY
HHHHHHHCCCCCCCEEEEECCHHHHHHCCCCEEEEECCHHHHHHCCCCCEEEEEECCCCC
LSEEKCTGCGSCEEVCPITVPNEFDMGIGMRKAIYKPFPQAVPAKYTIDKESCIDCGLCA
CCCCCCCCCCCCCCCCCEECCCCCCCCCCHHHHHHCCCCCCCCCEEEECHHHHCCHHHHH
KVCGPQAINYNQKPEIIEAEIGTIISAIGYDPYDPTEKEEYGYGKIPNVITSMELERMIN
HHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHC
ASGPTMGKVIRPSDGKKPKRIAFIQCVGSRDAKIGKKYCSNVCCMYAMKNSQLIKEKSPE
CCCCCCCCEECCCCCCCCCEEEEEEEECCCCHHHHHHHHCCCEEEEEECCCHHHHCCCCC
TEIDIYYMDIRAFSKGYEEFYERSSKQYGIKFIRGRPAQVLDNPKTDNPTIRSEDTLLGE
CEEEEEEEEHHHHHHHHHHHHHCCCHHCCEEEECCCCHHHHCCCCCCCCCCCCCCHHHHH
IFENDYDLVVLSVGMVPSKSADEVQKLLGVSRTTDRFFMEAHPKLKPVDTATDGVYLAGA
HHCCCCCEEEEEECCCCCCCHHHHHHHHCCCCCCHHHHHHCCCCCCCCCCCCCCEEEEEC
CQGPKDIPASVAQGSAAASRAAIPLAKGEVQVEPIVVTLDEDVCGACGICVQQCPYGAPR
CCCCCCCCHHHHCCCHHHHHCCCEECCCCEEEEEEEEEECCCCCCHHHHHHHHCCCCCCH
FVEKDGKQALEVLSALCKGCGTCAGGCPSGALEQSHFKTNQIYGQIEGVFKDSY
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHEEEEECCCC
>Mature Secondary Structure
MEEPKIGVYVCHCGVNIGGVVDCENVAKTAEGLKNVVISREYKYMCADPGQELIKKDIKE
CCCCCEEEEEEEECCCCCCEEEHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHH
LGLNRVIVAACSPRLHEPTFRRCVEEAGLNPFLFEFANIREHCSWVHMKEKEKATEKAND
CCCCEEEEEECCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVRMAVAKARQLDPLDYLTVPVTRRALVIGAGVAGIQAALDLGDSGYETILVEKTPSVGG
HHHHHHHHHHCCCCCCEEECCCCCEEEEEECCHHHHHHHHHCCCCCCEEEEEECCCCCCC
RMAQLDKVFPTNDCSICILAPKMVDVAKHPNIKLYSYSEVKDVSGYIGNFKVKIEKKPRY
HHHHHHHCCCCCCCEEEEECCHHHHHHCCCCEEEEECCHHHHHHCCCCCEEEEEECCCCC
LSEEKCTGCGSCEEVCPITVPNEFDMGIGMRKAIYKPFPQAVPAKYTIDKESCIDCGLCA
CCCCCCCCCCCCCCCCCEECCCCCCCCCCHHHHHHCCCCCCCCCEEEECHHHHCCHHHHH
KVCGPQAINYNQKPEIIEAEIGTIISAIGYDPYDPTEKEEYGYGKIPNVITSMELERMIN
HHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHC
ASGPTMGKVIRPSDGKKPKRIAFIQCVGSRDAKIGKKYCSNVCCMYAMKNSQLIKEKSPE
CCCCCCCCEECCCCCCCCCEEEEEEEECCCCHHHHHHHHCCCEEEEEECCCHHHHCCCCC
TEIDIYYMDIRAFSKGYEEFYERSSKQYGIKFIRGRPAQVLDNPKTDNPTIRSEDTLLGE
CEEEEEEEEHHHHHHHHHHHHHCCCHHCCEEEECCCCHHHHCCCCCCCCCCCCCCHHHHH
IFENDYDLVVLSVGMVPSKSADEVQKLLGVSRTTDRFFMEAHPKLKPVDTATDGVYLAGA
HHCCCCCEEEEEECCCCCCCHHHHHHHHCCCCCCHHHHHHCCCCCCCCCCCCCCEEEEEC
CQGPKDIPASVAQGSAAASRAAIPLAKGEVQVEPIVVTLDEDVCGACGICVQQCPYGAPR
CCCCCCCCHHHHCCCHHHHHCCCEECCCCEEEEEEEEEECCCCCCHHHHHHHHCCCCCCH
FVEKDGKQALEVLSALCKGCGTCAGGCPSGALEQSHFKTNQIYGQIEGVFKDSY
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9063468; 11930014 [H]