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The map label for this gene is kinB [H]

Identifier: 150010494

GI number: 150010494

Start: 4771238

End: 4772956

Strand: Direct

Name: kinB [H]

Synonym: BDI_3935

Alternate gene names: 150010494

Gene position: 4771238-4772956 (Clockwise)

Preceding gene: 150010493

Following gene: 150010495

Centisome position: 99.17

GC content: 44.04

Gene sequence:

>1719_bases
ATGAATATGAATATAAAAACAAAGTTGACTTATGGGATAGGACTTTTATTTGTCCTGATCACTTTATTAGGTGGATTGGC
TATAAAAAACATTCATAATGTATCGGATGACACGCAGAATATCCTAGCGGATAATTATAATTCACTCCTTTATTCCCGTC
AGATGCTCGAGTCACTGGATGCCATTCGGGAAAATCCGAATGCTCGAAAAGAGTTTGAGGCCGGGTTGGAAGCTCAGAAA
AAAAATCTGACAGAGAAGGATGAAGACGTACTAACCAACCGATTAAGTTCGAACTGTGAAAAGGCGTTGGATGACATGGA
TGATGAATCGATTCGGCAGATACGCCAGACGATTTATACCATTATGGCAGTCAATATGTCTGCCATTTATGAAAAGAATG
AAGTGGCTGTCCATACGGCGGAAAGGTCTCTCTTTTGGATCTGGACGGTAGGAATTGCTTGTATCGTGATCGCCTTCCTC
TTTCTGGCTCGCCTGCCACGCTCGGTCAGCGTACAGATCCAGAAATTGACGGATGGCATCAAGGAAATCACCAATGCCAA
TTACAGCAAACGGCTCAATTTGGGCAATGAACCGGAGTTTAAGGAAATAGCCACGTTGTTCAACGAGATGGCCGAGCGCT
TGGCCGAATACAGGAACAGTTCGCTGGAAGATATCCTGCAAGGGAAAAAATATATAGAAACAATTATCAACAGCATTGCA
GAACCTATCATAGGCTTGAGTAAGGAACGGAAGATTTTGTTTGTCAATGACGAGGCTTTGACTGTTTTGAATTTGACACG
GGAAAACATTATCGACAAACCGGCTCCCGAAGTGGCGTTAAAAAATGATCTGCTGCGCCGTTTGATCCGCCAGTTGGTAC
ATCCCGATGACAATAAGGATCCGTTGAAAATCTACGCAGACAACAAGGAAAGCTATTTTCAAGTAAAATACATCCCGATC
AACGTTAACAGGCAGACTGGACTGGAGAGTAAGTATGTCGGGGATGTGATCCTGTTGAAGAACGTGACCGAATTTAAAGA
AAAAGATATTGCAAAGACAACCTTTATTTCAACGATCTCTCATGAACTGAAGACACCGATATCTGCTATCATGATGAGTT
TGGAACTGCTGGAAGACAATCGGATCGGAAAACTGAATACAGAACAGGAGAGCCTTTCCAAGAACATAAAGGAAAATAGT
GACCGTTTGTTGGAGATCACTGGCGAATTGTTGAAGATGTCACAGGTAGAAAGCGGTAAGCTCTACCTGAATCCGAAGAT
TACCAAACCGATCGAACTGATCGACTATGCCATCAAGGCGAACCGGGTACAGGCCGAGCGTTTTAACTGTCAGATCGAAG
TGGAGTATCCTGAAAAGATCACCAAATTGTTTGTCGACAGCGAGAAAATTGCTTGGGTTGTGACCAACCTGTTATCGAAC
GCCATCCGTTATTCGTCGGAGAACGGACGGATTATCATCGGTGCACGACAGATCGACAAAGCCGTCGAGATCTATGTCAA
GGACTTCGGAAAGGGCATTGACTCGCGTTACCACGAAAGTATTTTCGACCACTATTTCCGTGTGCCGGGAACAAAAGTAC
AAGGTAGCGGTTTGGGACTTGCCATCAGCAAGGACTTTGTGGAAGCTCATGGTGGTACGATCCGTATCGAAAGCGAAGTC
GGTAAAGGTAGCACGTTCGTGATCAGATTCAATGTATAA

Upstream 100 bases:

>100_bases
TATCCTTCCGCTATCCTTGCGATGGTCCACTATCGGAACATGTTAGAAGAGTTGGCTCAATTAGGCATTGATTTAATAAT
ATTAGCATAAAAATCCTTCC

Downstream 100 bases:

>100_bases
AAAGTAAAATCAAAAATCAGATAGTCTAATGAAAGTATTAAAATTTGGTGGTACTTCAGTCGGTTCTGCCCAGCGGATCA
AGAATGTCGCATCAATCATT

Product: two-component system sensor histidine kinase, FrrD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 572; Mature: 572

Protein sequence:

>572_residues
MNMNIKTKLTYGIGLLFVLITLLGGLAIKNIHNVSDDTQNILADNYNSLLYSRQMLESLDAIRENPNARKEFEAGLEAQK
KNLTEKDEDVLTNRLSSNCEKALDDMDDESIRQIRQTIYTIMAVNMSAIYEKNEVAVHTAERSLFWIWTVGIACIVIAFL
FLARLPRSVSVQIQKLTDGIKEITNANYSKRLNLGNEPEFKEIATLFNEMAERLAEYRNSSLEDILQGKKYIETIINSIA
EPIIGLSKERKILFVNDEALTVLNLTRENIIDKPAPEVALKNDLLRRLIRQLVHPDDNKDPLKIYADNKESYFQVKYIPI
NVNRQTGLESKYVGDVILLKNVTEFKEKDIAKTTFISTISHELKTPISAIMMSLELLEDNRIGKLNTEQESLSKNIKENS
DRLLEITGELLKMSQVESGKLYLNPKITKPIELIDYAIKANRVQAERFNCQIEVEYPEKITKLFVDSEKIAWVVTNLLSN
AIRYSSENGRIIIGARQIDKAVEIYVKDFGKGIDSRYHESIFDHYFRVPGTKVQGSGLGLAISKDFVEAHGGTIRIESEV
GKGSTFVIRFNV

Sequences:

>Translated_572_residues
MNMNIKTKLTYGIGLLFVLITLLGGLAIKNIHNVSDDTQNILADNYNSLLYSRQMLESLDAIRENPNARKEFEAGLEAQK
KNLTEKDEDVLTNRLSSNCEKALDDMDDESIRQIRQTIYTIMAVNMSAIYEKNEVAVHTAERSLFWIWTVGIACIVIAFL
FLARLPRSVSVQIQKLTDGIKEITNANYSKRLNLGNEPEFKEIATLFNEMAERLAEYRNSSLEDILQGKKYIETIINSIA
EPIIGLSKERKILFVNDEALTVLNLTRENIIDKPAPEVALKNDLLRRLIRQLVHPDDNKDPLKIYADNKESYFQVKYIPI
NVNRQTGLESKYVGDVILLKNVTEFKEKDIAKTTFISTISHELKTPISAIMMSLELLEDNRIGKLNTEQESLSKNIKENS
DRLLEITGELLKMSQVESGKLYLNPKITKPIELIDYAIKANRVQAERFNCQIEVEYPEKITKLFVDSEKIAWVVTNLLSN
AIRYSSENGRIIIGARQIDKAVEIYVKDFGKGIDSRYHESIFDHYFRVPGTKVQGSGLGLAISKDFVEAHGGTIRIESEV
GKGSTFVIRFNV
>Mature_572_residues
MNMNIKTKLTYGIGLLFVLITLLGGLAIKNIHNVSDDTQNILADNYNSLLYSRQMLESLDAIRENPNARKEFEAGLEAQK
KNLTEKDEDVLTNRLSSNCEKALDDMDDESIRQIRQTIYTIMAVNMSAIYEKNEVAVHTAERSLFWIWTVGIACIVIAFL
FLARLPRSVSVQIQKLTDGIKEITNANYSKRLNLGNEPEFKEIATLFNEMAERLAEYRNSSLEDILQGKKYIETIINSIA
EPIIGLSKERKILFVNDEALTVLNLTRENIIDKPAPEVALKNDLLRRLIRQLVHPDDNKDPLKIYADNKESYFQVKYIPI
NVNRQTGLESKYVGDVILLKNVTEFKEKDIAKTTFISTISHELKTPISAIMMSLELLEDNRIGKLNTEQESLSKNIKENS
DRLLEITGELLKMSQVESGKLYLNPKITKPIELIDYAIKANRVQAERFNCQIEVEYPEKITKLFVDSEKIAWVVTNLLSN
AIRYSSENGRIIIGARQIDKAVEIYVKDFGKGIDSRYHESIFDHYFRVPGTKVQGSGLGLAISKDFVEAHGGTIRIESEV
GKGSTFVIRFNV

Specific function: Member of the two-component regulatory system AlgB/KinB involved in regulation of alginate biosynthesis genes. KinB functions as a membrane-associated protein kinase that phosphorylates AlgB, probably in response to environmental signals [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI145693157, Length=229, Percent_Identity=34.061135371179, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI48994928, Length=286, Percent_Identity=28.6713286713287, Blast_Score=106, Evalue=4e-24,
Organism=Escherichia coli, GI87081816, Length=234, Percent_Identity=32.0512820512821, Blast_Score=105, Evalue=9e-24,
Organism=Escherichia coli, GI1790436, Length=245, Percent_Identity=29.7959183673469, Blast_Score=105, Evalue=9e-24,
Organism=Escherichia coli, GI1788713, Length=235, Percent_Identity=31.4893617021277, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1788549, Length=416, Percent_Identity=25, Blast_Score=96, Evalue=7e-21,
Organism=Escherichia coli, GI1786600, Length=235, Percent_Identity=25.531914893617, Blast_Score=96, Evalue=7e-21,
Organism=Escherichia coli, GI1788393, Length=203, Percent_Identity=29.5566502463054, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1786912, Length=227, Percent_Identity=28.1938325991189, Blast_Score=87, Evalue=4e-18,
Organism=Escherichia coli, GI1789149, Length=234, Percent_Identity=26.4957264957265, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1786783, Length=228, Percent_Identity=27.6315789473684, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI87082128, Length=226, Percent_Identity=27.8761061946903, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1790346, Length=230, Percent_Identity=25.6521739130435, Blast_Score=72, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013656
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF08448 PAS_4 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 65024; Mature: 65024

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: PS50885 HAMP ; PS50112 PAS ; PS50109 HIS_KIN ; PS00589 PTS_HPR_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNMNIKTKLTYGIGLLFVLITLLGGLAIKNIHNVSDDTQNILADNYNSLLYSRQMLESLD
CCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHH
AIRENPNARKEFEAGLEAQKKNLTEKDEDVLTNRLSSNCEKALDDMDDESIRQIRQTIYT
HHHCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
IMAVNMSAIYEKNEVAVHTAERSLFWIWTVGIACIVIAFLFLARLPRSVSVQIQKLTDGI
HHHHHHHHHHCCCCEEEEECCCCEEHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
KEITNANYSKRLNLGNEPEFKEIATLFNEMAERLAEYRNSSLEDILQGKKYIETIINSIA
HHHHCCCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
EPIIGLSKERKILFVNDEALTVLNLTRENIIDKPAPEVALKNDLLRRLIRQLVHPDDNKD
HHHHCCCCCCEEEEECCCCEEEEECHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCC
PLKIYADNKESYFQVKYIPINVNRQTGLESKYVGDVILLKNVTEFKEKDIAKTTFISTIS
CEEEEECCCCCEEEEEEEEEECCCCCCCCCHHCCCCCEECCHHHHHHHHHHHHHHHHHHH
HELKTPISAIMMSLELLEDNRIGKLNTEQESLSKNIKENSDRLLEITGELLKMSQVESGK
HHHHCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCE
LYLNPKITKPIELIDYAIKANRVQAERFNCQIEVEYPEKITKLFVDSEKIAWVVTNLLSN
EEECCCCCCHHHHHHHHHHCCCEEHHHCCEEEEEECHHHHHHHHCCCCHHHHHHHHHHHH
AIRYSSENGRIIIGARQIDKAVEIYVKDFGKGIDSRYHESIFDHYFRVPGTKVQGSGLGL
HHHCCCCCCEEEEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCEECCCCCEE
AISKDFVEAHGGTIRIESEVGKGSTFVIRFNV
EEEHHHHHHCCCEEEEECCCCCCCEEEEEEEC
>Mature Secondary Structure
MNMNIKTKLTYGIGLLFVLITLLGGLAIKNIHNVSDDTQNILADNYNSLLYSRQMLESLD
CCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHH
AIRENPNARKEFEAGLEAQKKNLTEKDEDVLTNRLSSNCEKALDDMDDESIRQIRQTIYT
HHHCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
IMAVNMSAIYEKNEVAVHTAERSLFWIWTVGIACIVIAFLFLARLPRSVSVQIQKLTDGI
HHHHHHHHHHCCCCEEEEECCCCEEHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
KEITNANYSKRLNLGNEPEFKEIATLFNEMAERLAEYRNSSLEDILQGKKYIETIINSIA
HHHHCCCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
EPIIGLSKERKILFVNDEALTVLNLTRENIIDKPAPEVALKNDLLRRLIRQLVHPDDNKD
HHHHCCCCCCEEEEECCCCEEEEECHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCC
PLKIYADNKESYFQVKYIPINVNRQTGLESKYVGDVILLKNVTEFKEKDIAKTTFISTIS
CEEEEECCCCCEEEEEEEEEECCCCCCCCCHHCCCCCEECCHHHHHHHHHHHHHHHHHHH
HELKTPISAIMMSLELLEDNRIGKLNTEQESLSKNIKENSDRLLEITGELLKMSQVESGK
HHHHCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCE
LYLNPKITKPIELIDYAIKANRVQAERFNCQIEVEYPEKITKLFVDSEKIAWVVTNLLSN
EEECCCCCCHHHHHHHHHHCCCEEHHHCCEEEEEECHHHHHHHHCCCCHHHHHHHHHHHH
AIRYSSENGRIIIGARQIDKAVEIYVKDFGKGIDSRYHESIFDHYFRVPGTKVQGSGLGL
HHHCCCCCCEEEEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCEECCCCCEE
AISKDFVEAHGGTIRIESEVGKGSTFVIRFNV
EEEHHHHHHCCCEEEEECCCCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9218420 [H]