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The map label for this gene is kdpD [H]

Identifier: 150010493

GI number: 150010493

Start: 4770106

End: 4771227

Strand: Direct

Name: kdpD [H]

Synonym: BDI_3934

Alternate gene names: 150010493

Gene position: 4770106-4771227 (Clockwise)

Preceding gene: 150010492

Following gene: 150010494

Centisome position: 99.14

GC content: 43.32

Gene sequence:

>1122_bases
ATGGACCGAGAACAAAGTGTACAACATTTTTTAGATTTGTTGAAAAAGTCTCGTCGTGGCAATTTTAAAATCTACATCGG
CATGATTGCCGGTGTAGGTAAATCGTATCGGATGCTATCAGATGCCCACCAATTACTGGAAAGCGGTATCGATGTCAAGA
TCGGTTATATAGAAACACATGGGCGAGTCGAGACGGAGGCATTGGTGGAAGGATTGCCTATCATCCCCCGCCGCAAGATA
TTTTATAAAGGAAAAGAGATCGAAGAGATGGACTTGCAGTCGATTCTCAGTATCCATCCTGAAGTTGTCATCGTTGACGA
ATTGGCTCATACCAATGTCGAAGGCAGTAAGAACGAAAAGCGTTGGCAGGATGTCATGGATATACTGGATGCCGGTATCA
GTGTGATCACGGCGGTCAATATTCAGCATATAGAAGGACTTAACGAGATGGTGCAGGACGTGGTTGGCATTGAGGTCAAG
GAACGTATTCCTGATATCGTACTGGAGCAGGCTGATGAAGTGGTCAACATAGACCTTACTGCTGACGAACTGCTGGCTCG
GTTAAAAGCCGGAAAAATATACAAACCCGATAAGATACAAACAGCATTAAATAATTTCTTTAAGGCTGAACATATTCTTC
AGCTTAGGGAGTTGGCATTGAAAGAGGTAGCTTTGCGGGTAGAAAAAAAAGTGGAGAATACCATTCCAGAGAATCTCGGC
GTACGCCACGAAAGGTTTATGGCCTGCATCAGCAGTAATGAGAAAACTCCCCGTAAGATCATACGGAAAGTCGCACGGTT
GGCAACCCGATATAATTCCAAGTTTTTTGTACTGTATGTACAAACCCCAAGAGAAAGTTCCGACAGGATTCCGTTGGCAA
GTCAAAGGCATTTGCTTAACCATTTCAAGTTGGCAACGGAACTTGGAGGAGAAATCATTCAAGTGCAATCCCCACATATA
ACGGATGCGATCGTACAGGCTTGTAAAGAAAAGCAAATCAGTACGCTATGTATCGGACGACCAGCTTTAAAATATCCTTC
CGCTATCCTTGCGATGGTCCACTATCGGAACATGTTAGAAGAGTTGGCTCAATTAGGCATTGATTTAATAATATTAGCAT
AA

Upstream 100 bases:

>100_bases
TTCTCATTACCTATTTTTACACAGGCAATTTGGAACCCTCGCATGGAGGATGCCCATCTTGTCTTGGGAATTTCTTTAAG
ACCTTGATATAATAATACGC

Downstream 100 bases:

>100_bases
AAATCCTTCCATGAATATGAATATAAAAACAAAGTTGACTTATGGGATAGGACTTTTATTTGTCCTGATCACTTTATTAG
GTGGATTGGCTATAAAAAAC

Product: osmosensitive K+ channel histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 373; Mature: 373

Protein sequence:

>373_residues
MDREQSVQHFLDLLKKSRRGNFKIYIGMIAGVGKSYRMLSDAHQLLESGIDVKIGYIETHGRVETEALVEGLPIIPRRKI
FYKGKEIEEMDLQSILSIHPEVVIVDELAHTNVEGSKNEKRWQDVMDILDAGISVITAVNIQHIEGLNEMVQDVVGIEVK
ERIPDIVLEQADEVVNIDLTADELLARLKAGKIYKPDKIQTALNNFFKAEHILQLRELALKEVALRVEKKVENTIPENLG
VRHERFMACISSNEKTPRKIIRKVARLATRYNSKFFVLYVQTPRESSDRIPLASQRHLLNHFKLATELGGEIIQVQSPHI
TDAIVQACKEKQISTLCIGRPALKYPSAILAMVHYRNMLEELAQLGIDLIILA

Sequences:

>Translated_373_residues
MDREQSVQHFLDLLKKSRRGNFKIYIGMIAGVGKSYRMLSDAHQLLESGIDVKIGYIETHGRVETEALVEGLPIIPRRKI
FYKGKEIEEMDLQSILSIHPEVVIVDELAHTNVEGSKNEKRWQDVMDILDAGISVITAVNIQHIEGLNEMVQDVVGIEVK
ERIPDIVLEQADEVVNIDLTADELLARLKAGKIYKPDKIQTALNNFFKAEHILQLRELALKEVALRVEKKVENTIPENLG
VRHERFMACISSNEKTPRKIIRKVARLATRYNSKFFVLYVQTPRESSDRIPLASQRHLLNHFKLATELGGEIIQVQSPHI
TDAIVQACKEKQISTLCIGRPALKYPSAILAMVHYRNMLEELAQLGIDLIILA
>Mature_373_residues
MDREQSVQHFLDLLKKSRRGNFKIYIGMIAGVGKSYRMLSDAHQLLESGIDVKIGYIETHGRVETEALVEGLPIIPRRKI
FYKGKEIEEMDLQSILSIHPEVVIVDELAHTNVEGSKNEKRWQDVMDILDAGISVITAVNIQHIEGLNEMVQDVVGIEVK
ERIPDIVLEQADEVVNIDLTADELLARLKAGKIYKPDKIQTALNNFFKAEHILQLRELALKEVALRVEKKVENTIPENLG
VRHERFMACISSNEKTPRKIIRKVARLATRYNSKFFVLYVQTPRESSDRIPLASQRHLLNHFKLATELGGEIIQVQSPHI
TDAIVQACKEKQISTLCIGRPALKYPSAILAMVHYRNMLEELAQLGIDLIILA

Specific function: Member of the two-component regulatory system kdpD/kdpE involved in the regulation of the kdp operon. KdpD may function as a membrane-associated protein kinase that phosphorylates kdpE in response to environmental signals [H]

COG id: COG2205

COG function: function code T; Osmosensitive K+ channel histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1786912, Length=328, Percent_Identity=40.2439024390244, Blast_Score=268, Evalue=4e-73,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR003852
- InterPro:   IPR006016 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF02702 KdpD; PF00582 Usp [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 42331; Mature: 42331

Theoretical pI: Translated: 7.16; Mature: 7.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDREQSVQHFLDLLKKSRRGNFKIYIGMIAGVGKSYRMLSDAHQLLESGIDVKIGYIETH
CCHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCHHHHHHHHHHHHHHCCCCEEEEEEECC
GRVETEALVEGLPIIPRRKIFYKGKEIEEMDLQSILSIHPEVVIVDELAHTNVEGSKNEK
CCCHHHHHHCCCCCCCCCHHEECCCCCHHHHHHHHHHCCCCEEEEECHHHCCCCCCCCHH
RWQDVMDILDAGISVITAVNIQHIEGLNEMVQDVVGIEVKERIPDIVLEQADEVVNIDLT
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEEEECC
ADELLARLKAGKIYKPDKIQTALNNFFKAEHILQLRELALKEVALRVEKKVENTIPENLG
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCC
VRHERFMACISSNEKTPRKIIRKVARLATRYNSKFFVLYVQTPRESSDRIPLASQRHLLN
CHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCCHHHHHHHH
HFKLATELGGEIIQVQSPHITDAIVQACKEKQISTLCIGRPALKYPSAILAMVHYRNMLE
HHHHHHHHCCCEEEECCCCHHHHHHHHHHHHCHHHHCCCCCCHHHHHHHHHHHHHHHHHH
ELAQLGIDLIILA
HHHHCCCCEEEEC
>Mature Secondary Structure
MDREQSVQHFLDLLKKSRRGNFKIYIGMIAGVGKSYRMLSDAHQLLESGIDVKIGYIETH
CCHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCHHHHHHHHHHHHHHCCCCEEEEEEECC
GRVETEALVEGLPIIPRRKIFYKGKEIEEMDLQSILSIHPEVVIVDELAHTNVEGSKNEK
CCCHHHHHHCCCCCCCCCHHEECCCCCHHHHHHHHHHCCCCEEEEECHHHCCCCCCCCHH
RWQDVMDILDAGISVITAVNIQHIEGLNEMVQDVVGIEVKERIPDIVLEQADEVVNIDLT
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEEEECC
ADELLARLKAGKIYKPDKIQTALNNFFKAEHILQLRELALKEVALRVEKKVENTIPENLG
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCC
VRHERFMACISSNEKTPRKIIRKVARLATRYNSKFFVLYVQTPRESSDRIPLASQRHLLN
CHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCCHHHHHHHH
HFKLATELGGEIIQVQSPHITDAIVQACKEKQISTLCIGRPALKYPSAILAMVHYRNMLE
HHHHHHHHCCCEEEECCCCHHHHHHHHHHHHCHHHHCCCCCCHHHHHHHHHHHHHHHHHH
ELAQLGIDLIILA
HHHHCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1532388; 8905232; 9278503; 7499326 [H]