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The map label for this gene is ahpC [H]

Identifier: 150009977

GI number: 150009977

Start: 4130022

End: 4130588

Strand: Direct

Name: ahpC [H]

Synonym: BDI_3396

Alternate gene names: 150009977

Gene position: 4130022-4130588 (Clockwise)

Preceding gene: 150009976

Following gene: 150009978

Centisome position: 85.84

GC content: 43.39

Gene sequence:

>567_bases
ATGGAACCGATTATTAATTCTCAACTTCCGGAGTTTAAAGTACAAGCTTTTCAAAATGGTAATTTCAAGACTGTAACCAA
CGAGGACGTTTTGGGTAAGTGGGCTATCTTTTTCTTCTACCCGGCCGATTTTACATTTGTTTGTCCAACAGAGTTGGTCG
ATATGGCTGAGAAGTATGAGCAGTTTAAATCAATGGGAGTAGAAATTTACTCTGTAAGTACAGACTCTCATTTTGTACAT
AAAGCTTGGCATGACGCTTCCGAGACTATCCGTAAGATCCAATATCCGATGTTGGCGGATCCCACTGGAGCACTGAGTCG
TGCGTTTGGTGTGATGATTGAGGAAGAGGGTATGGCATACCGTGGCACTTTCTTGGTAAATCCGGAAGGAAAGATCAAAG
TGGCCGAGATTCATGATAACAATATCGGTCGTGACGCTTCCGAGTTACTTCGTAAAGTTGAAGCCGCTCAGTTTGTCGCT
TCACATGATGGTGAGGTTTGTCCCGCTAAATGGAAGAAAGGGGAGGCTACCTTGAAACCTAGCATTGACTTGGTAGGGAA
AATCTAA

Upstream 100 bases:

>100_bases
AAAATATATCGATTAGAAAAATTGTTTTAATGAAGAAATATGTTATATTTTTGTATCGGAAATAAAAACAAATAGTATTC
ATTTAAAAATAGGAACAAGT

Downstream 100 bases:

>100_bases
ATAATTAAGAGTATAGATCGTGTTAGAATCAACATTAAAAGAACAATTAAAAGGTATATTCGCAGGGTTAAATGCGAATT
ATACCTTTGATATATCGATC

Product: alkyl hydroperoxide reductase subunit C

Products: NA

Alternate protein names: Alkyl hydroperoxide reductase protein C22; Peroxiredoxin; SCRP-23; Sulfate starvation-induced protein 8; SSI8; Thioredoxin peroxidase [H]

Number of amino acids: Translated: 188; Mature: 188

Protein sequence:

>188_residues
MEPIINSQLPEFKVQAFQNGNFKTVTNEDVLGKWAIFFFYPADFTFVCPTELVDMAEKYEQFKSMGVEIYSVSTDSHFVH
KAWHDASETIRKIQYPMLADPTGALSRAFGVMIEEEGMAYRGTFLVNPEGKIKVAEIHDNNIGRDASELLRKVEAAQFVA
SHDGEVCPAKWKKGEATLKPSIDLVGKI

Sequences:

>Translated_188_residues
MEPIINSQLPEFKVQAFQNGNFKTVTNEDVLGKWAIFFFYPADFTFVCPTELVDMAEKYEQFKSMGVEIYSVSTDSHFVH
KAWHDASETIRKIQYPMLADPTGALSRAFGVMIEEEGMAYRGTFLVNPEGKIKVAEIHDNNIGRDASELLRKVEAAQFVA
SHDGEVCPAKWKKGEATLKPSIDLVGKI
>Mature_188_residues
MEPIINSQLPEFKVQAFQNGNFKTVTNEDVLGKWAIFFFYPADFTFVCPTELVDMAEKYEQFKSMGVEIYSVSTDSHFVH
KAWHDASETIRKIQYPMLADPTGALSRAFGVMIEEEGMAYRGTFLVNPEGKIKVAEIHDNNIGRDASELLRKVEAAQFVA
SHDGEVCPAKWKKGEATLKPSIDLVGKI

Specific function: Directly reduces organic hydroperoxides in its reduced dithiol form [H]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI32189392, Length=182, Percent_Identity=42.3076923076923, Blast_Score=162, Evalue=2e-40,
Organism=Homo sapiens, GI32483377, Length=179, Percent_Identity=43.5754189944134, Blast_Score=160, Evalue=7e-40,
Organism=Homo sapiens, GI5802974, Length=182, Percent_Identity=42.3076923076923, Blast_Score=160, Evalue=9e-40,
Organism=Homo sapiens, GI4505591, Length=182, Percent_Identity=38.4615384615385, Blast_Score=154, Evalue=7e-38,
Organism=Homo sapiens, GI32455266, Length=182, Percent_Identity=38.4615384615385, Blast_Score=154, Evalue=7e-38,
Organism=Homo sapiens, GI32455264, Length=182, Percent_Identity=38.4615384615385, Blast_Score=154, Evalue=7e-38,
Organism=Homo sapiens, GI5453549, Length=187, Percent_Identity=38.5026737967914, Blast_Score=145, Evalue=2e-35,
Organism=Homo sapiens, GI33188454, Length=81, Percent_Identity=45.679012345679, Blast_Score=87, Evalue=6e-18,
Organism=Homo sapiens, GI4758638, Length=163, Percent_Identity=30.6748466257669, Blast_Score=76, Evalue=2e-14,
Organism=Escherichia coli, GI1786822, Length=185, Percent_Identity=62.7027027027027, Blast_Score=261, Evalue=3e-71,
Organism=Caenorhabditis elegans, GI17554494, Length=179, Percent_Identity=40.2234636871508, Blast_Score=162, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI32565831, Length=181, Percent_Identity=41.9889502762431, Blast_Score=159, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI193204376, Length=181, Percent_Identity=41.9889502762431, Blast_Score=159, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI25153706, Length=193, Percent_Identity=25.3886010362694, Blast_Score=73, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6323613, Length=182, Percent_Identity=39.010989010989, Blast_Score=139, Evalue=2e-34,
Organism=Saccharomyces cerevisiae, GI6320661, Length=181, Percent_Identity=37.0165745856354, Blast_Score=135, Evalue=3e-33,
Organism=Saccharomyces cerevisiae, GI6319407, Length=189, Percent_Identity=26.4550264550265, Blast_Score=76, Evalue=3e-15,
Organism=Drosophila melanogaster, GI17738015, Length=179, Percent_Identity=40.7821229050279, Blast_Score=157, Evalue=4e-39,
Organism=Drosophila melanogaster, GI21357347, Length=186, Percent_Identity=37.6344086021505, Blast_Score=149, Evalue=1e-36,
Organism=Drosophila melanogaster, GI17157991, Length=179, Percent_Identity=37.4301675977654, Blast_Score=141, Evalue=2e-34,
Organism=Drosophila melanogaster, GI24641739, Length=179, Percent_Identity=37.4301675977654, Blast_Score=141, Evalue=2e-34,
Organism=Drosophila melanogaster, GI24656348, Length=181, Percent_Identity=35.9116022099448, Blast_Score=140, Evalue=7e-34,
Organism=Drosophila melanogaster, GI17864676, Length=181, Percent_Identity=35.9116022099448, Blast_Score=140, Evalue=7e-34,
Organism=Drosophila melanogaster, GI24581278, Length=150, Percent_Identity=32, Blast_Score=83, Evalue=1e-16,
Organism=Drosophila melanogaster, GI17975518, Length=156, Percent_Identity=28.8461538461538, Blast_Score=81, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24652436, Length=161, Percent_Identity=29.1925465838509, Blast_Score=81, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24652434, Length=156, Percent_Identity=28.8461538461538, Blast_Score=80, Evalue=6e-16,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR017559
- InterPro:   IPR019479
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 21126; Mature: 21126

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEPIINSQLPEFKVQAFQNGNFKTVTNEDVLGKWAIFFFYPADFTFVCPTELVDMAEKYE
CCCCCCCCCCCCEEEEECCCCEEEECCCCCCCEEEEEEEECCCEEEECHHHHHHHHHHHH
QFKSMGVEIYSVSTDSHFVHKAWHDASETIRKIQYPMLADPTGALSRAFGVMIEEEGMAY
HHHHCCEEEEEECCCCCHHHHHHCCHHHHHHHHCCCCCCCCCHHHHHHHCEEECCCCCEE
RGTFLVNPEGKIKVAEIHDNNIGRDASELLRKVEAAQFVASHDGEVCPAKWKKGEATLKP
EEEEEECCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEECC
SIDLVGKI
CCEEECCC
>Mature Secondary Structure
MEPIINSQLPEFKVQAFQNGNFKTVTNEDVLGKWAIFFFYPADFTFVCPTELVDMAEKYE
CCCCCCCCCCCCEEEEECCCCEEEECCCCCCCEEEEEEEECCCEEEECHHHHHHHHHHHH
QFKSMGVEIYSVSTDSHFVHKAWHDASETIRKIQYPMLADPTGALSRAFGVMIEEEGMAY
HHHHCCEEEEEECCCCCHHHHHHCCHHHHHHHHCCCCCCCCCHHHHHHHCEEECCCCCEE
RGTFLVNPEGKIKVAEIHDNNIGRDASELLRKVEAAQFVASHDGEVCPAKWKKGEATLKP
EEEEEECCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEECC
SIDLVGKI
CCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]