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The map label for this gene is rprX [H]

Identifier: 150009078

GI number: 150009078

Start: 2922242

End: 2923801

Strand: Direct

Name: rprX [H]

Synonym: BDI_2479

Alternate gene names: 150009078

Gene position: 2922242-2923801 (Clockwise)

Preceding gene: 150009077

Following gene: 150009079

Centisome position: 60.74

GC content: 42.5

Gene sequence:

>1560_bases
ATGAGGAAGTCGACAATTTGGTTGCTTGCGGTAGTTATGGCTTTTGCCTTCGCCGGGTTATTATACCTACAGGTAAACTA
TGTGAGCATTATACTTAAGACACGCAGCGAACAGTTCAATGAGACTGTCAAAAGAAGCCTGCGCCAAGTATCTAAGAATC
TGGAATTGGATGAGACCCGTAAATACCTCGAGGATGATATCAACCGGGATGAGACAAATTTCATGTATCAAAATGCCCCG
GATGCCCAAAGCCTAGGACAAGTGATCAACCATGAGAAATACCAATTACAGATCAAGGATTCTAATGGAACCGTTCAACA
AATAGAGATGCAAAGTTTTAGCGCCCATAAGTTCGAGCCGCTCTCTTCCTTGTCAAAACGGCAGTCTGCCAACAGCATCG
TAAACACATCTAAAGATTTACAGAAGACACTAAAAAGACGTTACCAGTACCAAGGTGGACTGATAGAGGAGGTGATTTAC
AACATCTTATACACTGCGAATCTAAAGCCGATCGAGGAACGTATAGATTTTAAAAAGCTGAACAATTACTTAAAAACAGA
ATTTATTAACAACGGTTTGAACTTGCCGTTTGTGTTTTCTGTTATTAACAAAGATGGAAATGTAGTATACCAGAGCGGAG
AATTCCAAAAGCAACCGATCGCCTCTGACGTGATCACCCAAGTGCTTTTCCCGAACGATCCCCCATCGAAACTAAACTAC
CTGAGAGTTTATTTTCCGACGAAAGGGGATTATATCTCAAGCTCTATTACTTTCATCGTTCCATCGGTTATATTCTCATT
GATCCTGTTGATAACCTTCGTCTTCACGATTTACATCGTATTCCGTCAGAAGAAGTTATCCGAGATGAAAAACGACTTTA
TCAACAACATGACGCACGAGTTGAAGACACCGGTATCCACGATCTCGCTCGCCGCCCAGATGTTGAAGGATTCGGATATA
ACGAAGAGTCCGGACGTATTCAAGCATATATCCGGCGTAATCAACGACGAGACGAAGCGATTGAGCTTCTTGGTCGAGAA
AGTGCTACAGATGTCTTTGTTCGAACGACAGAAAGCAGCGCTTAAATTGAAAGAAATTGACGCGAATGATTTGGTAGCGA
ACGTGGCTAACACCTTCGTTTTAAAGGTCGAGAAGTACGGCGGTACAATGGATATAGACCTGCAAGCTACAGAATCGGAT
ATATATGTGGATGAAATGCATATCACCAATGTATTGTTCAACTTGATGGATAATGCGGTTAAATACCGCCACCCGGAAGT
TCCGCTTACATTGATGGCACGCACTTGGAACGAGAACGGAAAGCTGTTGATCTCCGTGGAAGATAATGGTATCGGTATCA
AGAAAGAATATCTGAAAAAGGTATTCGACCGTTTCTTCCGCGTACCGACAGGCAACGTACATGACGTGAAAGGGTTCGGT
CTCGGACTCGCTTACGTACGCAAAATTATTGAGGACCACAAAGGTACGATCCGTGCCGAAAGTGGTGCGGGAAACATTGG
AACAAAATTTATTATTACTTTACCTCTTATAAAAAGTTAG

Upstream 100 bases:

>100_bases
GTATTATTAACATTTTAAACGGATTATTTTTACCTTTTTTGTGTAAATATTAAACTAAAACATACGTTATTTGTTGCAAT
ATTAAGAGAAAGATATTGAT

Downstream 100 bases:

>100_bases
TTATGGAAGAAAAACTAAAGATCTTCTTTTGTGAAGACGATGAGAATTTAGGAATGCTTTTAAGAGAATACTTACAAGCT
AAAGGGTATGTAACGGACCT

Product: two-component system sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 519; Mature: 519

Protein sequence:

>519_residues
MRKSTIWLLAVVMAFAFAGLLYLQVNYVSIILKTRSEQFNETVKRSLRQVSKNLELDETRKYLEDDINRDETNFMYQNAP
DAQSLGQVINHEKYQLQIKDSNGTVQQIEMQSFSAHKFEPLSSLSKRQSANSIVNTSKDLQKTLKRRYQYQGGLIEEVIY
NILYTANLKPIEERIDFKKLNNYLKTEFINNGLNLPFVFSVINKDGNVVYQSGEFQKQPIASDVITQVLFPNDPPSKLNY
LRVYFPTKGDYISSSITFIVPSVIFSLILLITFVFTIYIVFRQKKLSEMKNDFINNMTHELKTPVSTISLAAQMLKDSDI
TKSPDVFKHISGVINDETKRLSFLVEKVLQMSLFERQKAALKLKEIDANDLVANVANTFVLKVEKYGGTMDIDLQATESD
IYVDEMHITNVLFNLMDNAVKYRHPEVPLTLMARTWNENGKLLISVEDNGIGIKKEYLKKVFDRFFRVPTGNVHDVKGFG
LGLAYVRKIIEDHKGTIRAESGAGNIGTKFIITLPLIKS

Sequences:

>Translated_519_residues
MRKSTIWLLAVVMAFAFAGLLYLQVNYVSIILKTRSEQFNETVKRSLRQVSKNLELDETRKYLEDDINRDETNFMYQNAP
DAQSLGQVINHEKYQLQIKDSNGTVQQIEMQSFSAHKFEPLSSLSKRQSANSIVNTSKDLQKTLKRRYQYQGGLIEEVIY
NILYTANLKPIEERIDFKKLNNYLKTEFINNGLNLPFVFSVINKDGNVVYQSGEFQKQPIASDVITQVLFPNDPPSKLNY
LRVYFPTKGDYISSSITFIVPSVIFSLILLITFVFTIYIVFRQKKLSEMKNDFINNMTHELKTPVSTISLAAQMLKDSDI
TKSPDVFKHISGVINDETKRLSFLVEKVLQMSLFERQKAALKLKEIDANDLVANVANTFVLKVEKYGGTMDIDLQATESD
IYVDEMHITNVLFNLMDNAVKYRHPEVPLTLMARTWNENGKLLISVEDNGIGIKKEYLKKVFDRFFRVPTGNVHDVKGFG
LGLAYVRKIIEDHKGTIRAESGAGNIGTKFIITLPLIKS
>Mature_519_residues
MRKSTIWLLAVVMAFAFAGLLYLQVNYVSIILKTRSEQFNETVKRSLRQVSKNLELDETRKYLEDDINRDETNFMYQNAP
DAQSLGQVINHEKYQLQIKDSNGTVQQIEMQSFSAHKFEPLSSLSKRQSANSIVNTSKDLQKTLKRRYQYQGGLIEEVIY
NILYTANLKPIEERIDFKKLNNYLKTEFINNGLNLPFVFSVINKDGNVVYQSGEFQKQPIASDVITQVLFPNDPPSKLNY
LRVYFPTKGDYISSSITFIVPSVIFSLILLITFVFTIYIVFRQKKLSEMKNDFINNMTHELKTPVSTISLAAQMLKDSDI
TKSPDVFKHISGVINDETKRLSFLVEKVLQMSLFERQKAALKLKEIDANDLVANVANTFVLKVEKYGGTMDIDLQATESD
IYVDEMHITNVLFNLMDNAVKYRHPEVPLTLMARTWNENGKLLISVEDNGIGIKKEYLKKVFDRFFRVPTGNVHDVKGFG
LGLAYVRKIIEDHKGTIRAESGAGNIGTKFIITLPLIKS

Specific function: Member of the two-component regulatory system rprX/rprY. May activate rprY by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1790346, Length=226, Percent_Identity=26.9911504424779, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI145693157, Length=238, Percent_Identity=28.1512605042017, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI48994928, Length=240, Percent_Identity=27.9166666666667, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI87082128, Length=270, Percent_Identity=25.9259259259259, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1786600, Length=377, Percent_Identity=23.0769230769231, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1786783, Length=241, Percent_Identity=24.896265560166, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1790861, Length=205, Percent_Identity=26.8292682926829, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1786912, Length=235, Percent_Identity=29.3617021276596, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1790436, Length=276, Percent_Identity=27.536231884058, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1788393, Length=234, Percent_Identity=24.3589743589744, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1788713, Length=242, Percent_Identity=26.0330578512397, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1788549, Length=244, Percent_Identity=27.8688524590164, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1789808, Length=237, Percent_Identity=21.0970464135021, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787894, Length=228, Percent_Identity=28.0701754385965, Blast_Score=69, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 59375; Mature: 59375

Theoretical pI: Translated: 9.49; Mature: 9.49

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKSTIWLLAVVMAFAFAGLLYLQVNYVSIILKTRSEQFNETVKRSLRQVSKNLELDETR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
KYLEDDINRDETNFMYQNAPDAQSLGQVINHEKYQLQIKDSNGTVQQIEMQSFSAHKFEP
HHHHHHCCCCCCCEEECCCCCHHHHHHHHCCCEEEEEEECCCCCEEEEEHHHCCCCCCCH
LSSLSKRQSANSIVNTSKDLQKTLKRRYQYQGGLIEEVIYNILYTANLKPIEERIDFKKL
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHH
NNYLKTEFINNGLNLPFVFSVINKDGNVVYQSGEFQKQPIASDVITQVLFPNDPPSKLNY
HHHHHHHHHCCCCCCCEEEEEECCCCCEEEECCCCCCCCCHHHHHHHHHCCCCCCCCCCE
LRVYFPTKGDYISSSITFIVPSVIFSLILLITFVFTIYIVFRQKKLSEMKNDFINNMTHE
EEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKTPVSTISLAAQMLKDSDITKSPDVFKHISGVINDETKRLSFLVEKVLQMSLFERQKAA
HHCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
LKLKEIDANDLVANVANTFVLKVEKYGGTMDIDLQATESDIYVDEMHITNVLFNLMDNAV
HHHHHCCHHHHHHHHHHHEEEEEEECCCEEEEEEEECCCCEEEHHHHHHHHHHHHHHHHH
KYRHPEVPLTLMARTWNENGKLLISVEDNGIGIKKEYLKKVFDRFFRVPTGNVHDVKGFG
HHCCCCCCEEEEEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHH
LGLAYVRKIIEDHKGTIRAESGAGNIGTKFIITLPLIKS
HHHHHHHHHHHCCCCCEEECCCCCCCCCEEEEEECCCCC
>Mature Secondary Structure
MRKSTIWLLAVVMAFAFAGLLYLQVNYVSIILKTRSEQFNETVKRSLRQVSKNLELDETR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
KYLEDDINRDETNFMYQNAPDAQSLGQVINHEKYQLQIKDSNGTVQQIEMQSFSAHKFEP
HHHHHHCCCCCCCEEECCCCCHHHHHHHHCCCEEEEEEECCCCCEEEEEHHHCCCCCCCH
LSSLSKRQSANSIVNTSKDLQKTLKRRYQYQGGLIEEVIYNILYTANLKPIEERIDFKKL
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHH
NNYLKTEFINNGLNLPFVFSVINKDGNVVYQSGEFQKQPIASDVITQVLFPNDPPSKLNY
HHHHHHHHHCCCCCCCEEEEEECCCCCEEEECCCCCCCCCHHHHHHHHHCCCCCCCCCCE
LRVYFPTKGDYISSSITFIVPSVIFSLILLITFVFTIYIVFRQKKLSEMKNDFINNMTHE
EEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKTPVSTISLAAQMLKDSDITKSPDVFKHISGVINDETKRLSFLVEKVLQMSLFERQKAA
HHCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
LKLKEIDANDLVANVANTFVLKVEKYGGTMDIDLQATESDIYVDEMHITNVLFNLMDNAV
HHHHHCCHHHHHHHHHHHEEEEEEECCCEEEEEEEECCCCEEEHHHHHHHHHHHHHHHHH
KYRHPEVPLTLMARTWNENGKLLISVEDNGIGIKKEYLKKVFDRFFRVPTGNVHDVKGFG
HHCCCCCCEEEEEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHH
LGLAYVRKIIEDHKGTIRAESGAGNIGTKFIITLPLIKS
HHHHHHHHHHHCCCCCEEECCCCCCCCCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8469117 [H]