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The map label for this gene is rpfC [H]

Identifier: 150007965

GI number: 150007965

Start: 1544034

End: 1545578

Strand: Direct

Name: rpfC [H]

Synonym: BDI_1326

Alternate gene names: 150007965

Gene position: 1544034-1545578 (Clockwise)

Preceding gene: 150007963

Following gene: 150007998

Centisome position: 32.09

GC content: 42.78

Gene sequence:

>1545_bases
ATGAGGGTCATTTATCTTTTACTATCTTTTATGCTTTGTTTCTGTCCGGTCATGCAGGCGCAAAATACGACGAATCAATT
TATGAAACAGGCACAAAGCAGCCTGGAAAAAAAAGACTACACCAAAGCTCGTTATCTTTTTTTACAAGCTTACAAGAGCT
TATCCCAACAAGGTGATTACAAACAGGCAATCGATGCCGGTACGCAGGCGGCTTATCTATATTATTGCGAGAATTATTAC
CAAGAGGCATTCGATCTTTGCCGCCAGATGAACCAATTCATCTTAACCGAGGAACTGAAGTTGCAAAAATCGCTCTATGA
GCAACGCTTCCAAGTAACGAAAGAGCGGTTGGAAATGTATATTAAGCTAAAGAACGCCGCCCAAGCGCAAGTTCAACTCA
ATACATTAGATAATCTGGCCAGCCAAGCGGGTGATGAGAAGTTATCGAACAATTTATTATATACCCAAGCGGGTTATTAT
TATACGTTCGGGCAAAACGAGCAGGGGGACGCTGCTTTCCAGAAACTGATCAACCAGTATAAGGAGAAAAAAGAATACGA
CAAGGTGAACGATTGCTACCGGAACCTGATCTCTATCGCTCGTAAGGCAAACAACGCCCCACTGATGGAACGTACCTACG
ACAAATACATCGTATGGACGGATTCCGTAAAGGCTCTTACGGCAGAGGATAAGCTAGGGGCATTACAACAAAAATACGAT
CAGAGCCTACAGACAATACAGGAGAAAGACGATAAATTGTCTGTTAAGCAATATATGATTGTTGGACTTATTACATTCGT
GGTAATCCTTATAGCCGCCTTACTTTTCTTAGGATTCCTTTTGCTGCGCTTCATCGTGCTGAACAAGAAATTAAAGAAAA
TCATCCAGACGACAAACGAGCATAGCGAACAACAAGCCCAATTCATCCAAAACATATCGGTTCAGATGGAGCCTACCTTG
AACAAGCTTAGCGCATCCGCCAAGGAATTACAGGCGGTAGCTCCGAAGCAGGCCGAGGATGTATGGACACGGGTAGAGGC
TTTGAAACAGTTTACGGTTCATATCCAAGAGCTTTCCTCCTTGGAGAATACGTTGATGGAACCGTATGAGGTTAGTTCTT
TTAATGTAGGAAACTTCAGTAAGAAAATCGTGGAGAAGGTTAAAGGGGATATTCAGCCGGAGGTCAACCTCGTAACAGAC
GTGCCCCAATTGGAGATTAAGACGAACGCCGAGCATCTGGAACAAGTCTTATTGCATTTGTTAAAGAATGCCGCATTATA
TACTTCCAGCGGTAACATTCGTCTGGAATTTAAACGGAAAGGCGCTCATGTTTGCCAATTTATCATTACCGATAATGGTA
CAGGCATACCAGATGATCTAAAAGAGAACTTATTCAAGCCATTCAATGAGGCGAAGGATCTAGCACAAGGCGATGGTTTG
GGATTACCCATCTGCGCACTGATGGCTAGTAAATTAAACGGAACCCTATCTATCGATAAGGAATATAAGAAGGGATGCCG
GTTCGTCTTGGTATTGCAGATATAA

Upstream 100 bases:

>100_bases
CAAATCGTATCTTAAAATAAAATATCTATTATTTTTCCCCTGATATATTTTGTATGAATCCCAGTAAATACATATTTTTA
CTTCAAAAAAAATTTAAGTT

Downstream 100 bases:

>100_bases
AATAGACTCACTTTGTTTGTCTTTTTACCGCGATGCGGATGCAGTGACGCTACAATCCGGGTTGCAGTAACACTGCATCC
ACATCGCGGTATCACTGCAA

Product: putative two-component system sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 514; Mature: 514

Protein sequence:

>514_residues
MRVIYLLLSFMLCFCPVMQAQNTTNQFMKQAQSSLEKKDYTKARYLFLQAYKSLSQQGDYKQAIDAGTQAAYLYYCENYY
QEAFDLCRQMNQFILTEELKLQKSLYEQRFQVTKERLEMYIKLKNAAQAQVQLNTLDNLASQAGDEKLSNNLLYTQAGYY
YTFGQNEQGDAAFQKLINQYKEKKEYDKVNDCYRNLISIARKANNAPLMERTYDKYIVWTDSVKALTAEDKLGALQQKYD
QSLQTIQEKDDKLSVKQYMIVGLITFVVILIAALLFLGFLLLRFIVLNKKLKKIIQTTNEHSEQQAQFIQNISVQMEPTL
NKLSASAKELQAVAPKQAEDVWTRVEALKQFTVHIQELSSLENTLMEPYEVSSFNVGNFSKKIVEKVKGDIQPEVNLVTD
VPQLEIKTNAEHLEQVLLHLLKNAALYTSSGNIRLEFKRKGAHVCQFIITDNGTGIPDDLKENLFKPFNEAKDLAQGDGL
GLPICALMASKLNGTLSIDKEYKKGCRFVLVLQI

Sequences:

>Translated_514_residues
MRVIYLLLSFMLCFCPVMQAQNTTNQFMKQAQSSLEKKDYTKARYLFLQAYKSLSQQGDYKQAIDAGTQAAYLYYCENYY
QEAFDLCRQMNQFILTEELKLQKSLYEQRFQVTKERLEMYIKLKNAAQAQVQLNTLDNLASQAGDEKLSNNLLYTQAGYY
YTFGQNEQGDAAFQKLINQYKEKKEYDKVNDCYRNLISIARKANNAPLMERTYDKYIVWTDSVKALTAEDKLGALQQKYD
QSLQTIQEKDDKLSVKQYMIVGLITFVVILIAALLFLGFLLLRFIVLNKKLKKIIQTTNEHSEQQAQFIQNISVQMEPTL
NKLSASAKELQAVAPKQAEDVWTRVEALKQFTVHIQELSSLENTLMEPYEVSSFNVGNFSKKIVEKVKGDIQPEVNLVTD
VPQLEIKTNAEHLEQVLLHLLKNAALYTSSGNIRLEFKRKGAHVCQFIITDNGTGIPDDLKENLFKPFNEAKDLAQGDGL
GLPICALMASKLNGTLSIDKEYKKGCRFVLVLQI
>Mature_514_residues
MRVIYLLLSFMLCFCPVMQAQNTTNQFMKQAQSSLEKKDYTKARYLFLQAYKSLSQQGDYKQAIDAGTQAAYLYYCENYY
QEAFDLCRQMNQFILTEELKLQKSLYEQRFQVTKERLEMYIKLKNAAQAQVQLNTLDNLASQAGDEKLSNNLLYTQAGYY
YTFGQNEQGDAAFQKLINQYKEKKEYDKVNDCYRNLISIARKANNAPLMERTYDKYIVWTDSVKALTAEDKLGALQQKYD
QSLQTIQEKDDKLSVKQYMIVGLITFVVILIAALLFLGFLLLRFIVLNKKLKKIIQTTNEHSEQQAQFIQNISVQMEPTL
NKLSASAKELQAVAPKQAEDVWTRVEALKQFTVHIQELSSLENTLMEPYEVSSFNVGNFSKKIVEKVKGDIQPEVNLVTD
VPQLEIKTNAEHLEQVLLHLLKNAALYTSSGNIRLEFKRKGAHVCQFIITDNGTGIPDDLKENLFKPFNEAKDLAQGDGL
GLPICALMASKLNGTLSIDKEYKKGCRFVLVLQI

Specific function: Involved in the positive regulation of synthesis of extracellular enzymes and polysaccharide, and hence in pathogenicity. Can restore function to the non-pathogenic mutant 8237 [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI145693157, Length=243, Percent_Identity=25.9259259259259, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI48994928, Length=114, Percent_Identity=27.1929824561404, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF01627 Hpt; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 58893; Mature: 58893

Theoretical pI: Translated: 8.15; Mature: 8.15

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVIYLLLSFMLCFCPVMQAQNTTNQFMKQAQSSLEKKDYTKARYLFLQAYKSLSQQGDY
CHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
KQAIDAGTQAAYLYYCENYYQEAFDLCRQMNQFILTEELKLQKSLYEQRFQVTKERLEMY
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IKLKNAAQAQVQLNTLDNLASQAGDEKLSNNLLYTQAGYYYTFGQNEQGDAAFQKLINQY
HHHHCCHHHHEEHHHHHHHHHHCCHHHHHCCEEEEECCEEEECCCCCCCHHHHHHHHHHH
KEKKEYDKVNDCYRNLISIARKANNAPLMERTYDKYIVWTDSVKALTAEDKLGALQQKYD
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCEEEEECCCHHHCCHHHHHHHHHHHH
QSLQTIQEKDDKLSVKQYMIVGLITFVVILIAALLFLGFLLLRFIVLNKKLKKIIQTTNE
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
HSEQQAQFIQNISVQMEPTLNKLSASAKELQAVAPKQAEDVWTRVEALKQFTVHIQELSS
CHHHHHHHHHHCCCEECCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
LENTLMEPYEVSSFNVGNFSKKIVEKVKGDIQPEVNLVTDVPQLEIKTNAEHLEQVLLHL
HHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCEEEECCCCEEEECCHHHHHHHHHHH
LKNAALYTSSGNIRLEFKRKGAHVCQFIITDNGTGIPDDLKENLFKPFNEAKDLAQGDGL
HHCCEEEECCCCEEEEEECCCCEEEEEEEECCCCCCCHHHHHHHHCCHHHHHHHHCCCCC
GLPICALMASKLNGTLSIDKEYKKGCRFVLVLQI
CHHHHHHHHHHCCCCEEECHHHHCCCEEEEEEEC
>Mature Secondary Structure
MRVIYLLLSFMLCFCPVMQAQNTTNQFMKQAQSSLEKKDYTKARYLFLQAYKSLSQQGDY
CHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
KQAIDAGTQAAYLYYCENYYQEAFDLCRQMNQFILTEELKLQKSLYEQRFQVTKERLEMY
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IKLKNAAQAQVQLNTLDNLASQAGDEKLSNNLLYTQAGYYYTFGQNEQGDAAFQKLINQY
HHHHCCHHHHEEHHHHHHHHHHCCHHHHHCCEEEEECCEEEECCCCCCCHHHHHHHHHHH
KEKKEYDKVNDCYRNLISIARKANNAPLMERTYDKYIVWTDSVKALTAEDKLGALQQKYD
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCEEEEECCCHHHCCHHHHHHHHHHHH
QSLQTIQEKDDKLSVKQYMIVGLITFVVILIAALLFLGFLLLRFIVLNKKLKKIIQTTNE
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
HSEQQAQFIQNISVQMEPTLNKLSASAKELQAVAPKQAEDVWTRVEALKQFTVHIQELSS
CHHHHHHHHHHCCCEECCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
LENTLMEPYEVSSFNVGNFSKKIVEKVKGDIQPEVNLVTDVPQLEIKTNAEHLEQVLLHL
HHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCEEEECCCCEEEECCHHHHHHHHHHH
LKNAALYTSSGNIRLEFKRKGAHVCQFIITDNGTGIPDDLKENLFKPFNEAKDLAQGDGL
HHCCEEEECCCCEEEEEECCCCEEEEEEEECCCCCCCHHHHHHHHCCHHHHHHHHCCCCC
GLPICALMASKLNGTLSIDKEYKKGCRFVLVLQI
CHHHHHHHHHHCCCCEEECHHHHCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1645442 [H]