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The map label for this gene is cobQ

Identifier: 150007998

GI number: 150007998

Start: 1579019

End: 1580509

Strand: Direct

Name: cobQ

Synonym: BDI_1360

Alternate gene names: 150007998

Gene position: 1579019-1580509 (Clockwise)

Preceding gene: 150007965

Following gene: 150007999

Centisome position: 32.82

GC content: 48.16

Gene sequence:

>1491_bases
ATGAAGCAACACCTACGACCGATTATGTTTGTCGGAACCTGCTCTGATGCGGGTAAAAGCGTTATCAATGCGGCGTTTTG
CCGTATTTTCAAGCAAGATGGTTATCAACCGGCACCGTTCAAGGCACAAAATATGTCCCTCAATTCCTACTCTACCCCGG
AAGGCGGCGAGATGGGCCGGGCGCAAGTCGTACAAGCGGAGGCCTGCGGTATTTCCCCGCATACGGATATGAACCCGATA
TTACTAAAGCCGACAAATGATAAAAGCTCGCAAGTCGTATTAAACGGAAAGCCAGTCGGCAATATGTCCGCCAAGGATTA
TTTCGGGATACAAAACCAGAAGGAGGAGCTATTTAAGGAAGCCATCGAAGCCTTCAAGCGTCTGGAAGCTCGCTATAACC
CGATCGTATTGGAAGGAGCCGGAAGCATCTCCGAACTAAACCTGCGAGACCGGGATATCACCAATATGCGTATGGCGATC
GCTGCCGGAGCCTCTACCTATTTAGTTGCGGATATAGACCGTGGGGGCGTATTCGGCTCTGTATATGGAACGATCGCTTT
ATTACGACCGGAGGAACGAGTGTTAATGAAAGGGGTTATCATCAATAAGTTCCGTGGAGACGCCTCTTTATTCGAAGAAG
GACGGAGCCTATTAAAGGAATTGACTGGGATTCCCGTGGTCGGCGTAATTCCATGGTTTCGGGATATCAAGATAGAGGAA
GAGGATTCCGTAGCGTTGGATATGAAAAATAACACTTATAAAGACGGGAAAATCAATGTAGCTATCATCCTGCTGAAACG
AATGTCTAATTTCACGGATTTTGATGTATTGGAGATGGACCCCCGTTTCAATCCGTATTATACCAACAATATCGATGAGA
TAGAGAAAGCCGACATCATCCTGCTCCCCGGCTCAAAGAATACGTTATCGGACTTACAAAGCCTGCGGGCCAATGGGATA
GCGATGGCGATTATCCGGGCGCATAAAGCGGGTAAAAAGGTGATCGGTATTTGCGGTGGCTATCAAATGATGGGAGTCCG
CTTGGAAGATCCGGAAAGTATCGAGGGAAATATCCCGGCGATTCCCGGTCTCGGTCTTCTGCCTCAATGCACAGTCATCG
AGCAGGAGAAGATCACGAGACAAAGCGACTTTGCTTTCCTCCCCTCCTCGGAGAATAAGGATTGTAAAGGATACGAAATA
CATATGGGACGAACCACCTTATTGGGCGACGCCCCCGAACAGCCCGTAGCCCGACTGGAAGACGGACGAACGGACGGATA
TTACCTCAACAACCGATGCTGGGGAAGTTATATGCATGGTATCCTTGATAATCCGGCCGTATTGGACAACTTAGCTGAGG
GCTTTGACACGGAAACGACTACAGGCCCTTTCGATTATGCCGCTTTTAAGGAAGAGCAGTATGATAAACTCGCCGCCCTC
GTAAGGGAGCACGTGGATATGGAATATATTTATAACAGTATTAAAAACTAA

Upstream 100 bases:

>100_bases
ACAGGCCCATAACAAAATCTTCTTCTTTTTTCATATCTTCTCCTTAATAAAAAGGCCAAAAATACTACCTTTGTACACTG
TGTAAATAAAATCTATACAG

Downstream 100 bases:

>100_bases
TATCATGAACAGACGTACTTTTATGCAAAAAACCGGACTTATCATGTCCGGACTTACTTTATCGCCGCTTATCGGTAAAT
CGTATTCCTCCATATACGGA

Product: cobyric acid synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 496; Mature: 496

Protein sequence:

>496_residues
MKQHLRPIMFVGTCSDAGKSVINAAFCRIFKQDGYQPAPFKAQNMSLNSYSTPEGGEMGRAQVVQAEACGISPHTDMNPI
LLKPTNDKSSQVVLNGKPVGNMSAKDYFGIQNQKEELFKEAIEAFKRLEARYNPIVLEGAGSISELNLRDRDITNMRMAI
AAGASTYLVADIDRGGVFGSVYGTIALLRPEERVLMKGVIINKFRGDASLFEEGRSLLKELTGIPVVGVIPWFRDIKIEE
EDSVALDMKNNTYKDGKINVAIILLKRMSNFTDFDVLEMDPRFNPYYTNNIDEIEKADIILLPGSKNTLSDLQSLRANGI
AMAIIRAHKAGKKVIGICGGYQMMGVRLEDPESIEGNIPAIPGLGLLPQCTVIEQEKITRQSDFAFLPSSENKDCKGYEI
HMGRTTLLGDAPEQPVARLEDGRTDGYYLNNRCWGSYMHGILDNPAVLDNLAEGFDTETTTGPFDYAAFKEEQYDKLAAL
VREHVDMEYIYNSIKN

Sequences:

>Translated_496_residues
MKQHLRPIMFVGTCSDAGKSVINAAFCRIFKQDGYQPAPFKAQNMSLNSYSTPEGGEMGRAQVVQAEACGISPHTDMNPI
LLKPTNDKSSQVVLNGKPVGNMSAKDYFGIQNQKEELFKEAIEAFKRLEARYNPIVLEGAGSISELNLRDRDITNMRMAI
AAGASTYLVADIDRGGVFGSVYGTIALLRPEERVLMKGVIINKFRGDASLFEEGRSLLKELTGIPVVGVIPWFRDIKIEE
EDSVALDMKNNTYKDGKINVAIILLKRMSNFTDFDVLEMDPRFNPYYTNNIDEIEKADIILLPGSKNTLSDLQSLRANGI
AMAIIRAHKAGKKVIGICGGYQMMGVRLEDPESIEGNIPAIPGLGLLPQCTVIEQEKITRQSDFAFLPSSENKDCKGYEI
HMGRTTLLGDAPEQPVARLEDGRTDGYYLNNRCWGSYMHGILDNPAVLDNLAEGFDTETTTGPFDYAAFKEEQYDKLAAL
VREHVDMEYIYNSIKN
>Mature_496_residues
MKQHLRPIMFVGTCSDAGKSVINAAFCRIFKQDGYQPAPFKAQNMSLNSYSTPEGGEMGRAQVVQAEACGISPHTDMNPI
LLKPTNDKSSQVVLNGKPVGNMSAKDYFGIQNQKEELFKEAIEAFKRLEARYNPIVLEGAGSISELNLRDRDITNMRMAI
AAGASTYLVADIDRGGVFGSVYGTIALLRPEERVLMKGVIINKFRGDASLFEEGRSLLKELTGIPVVGVIPWFRDIKIEE
EDSVALDMKNNTYKDGKINVAIILLKRMSNFTDFDVLEMDPRFNPYYTNNIDEIEKADIILLPGSKNTLSDLQSLRANGI
AMAIIRAHKAGKKVIGICGGYQMMGVRLEDPESIEGNIPAIPGLGLLPQCTVIEQEKITRQSDFAFLPSSENKDCKGYEI
HMGRTTLLGDAPEQPVARLEDGRTDGYYLNNRCWGSYMHGILDNPAVLDNLAEGFDTETTTGPFDYAAFKEEQYDKLAAL
VREHVDMEYIYNSIKN

Specific function: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation

COG id: COG1492

COG function: function code H; Cobyric acid synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GATase cobBQ-type domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COBQ_PARD8 (A6LBQ5)

Other databases:

- EMBL:   CP000140
- RefSeq:   YP_001302741.1
- ProteinModelPortal:   A6LBQ5
- STRING:   A6LBQ5
- GeneID:   5306513
- GenomeReviews:   CP000140_GR
- KEGG:   pdi:BDI_1360
- eggNOG:   COG1492
- HOGENOM:   HBG302271
- OMA:   AHTDLNP
- ProtClustDB:   PRK00784
- BioCyc:   PDIS435591:BDI_1360-MONOMER
- HAMAP:   MF_00028
- InterPro:   IPR002586
- InterPro:   IPR017929
- InterPro:   IPR004459
- InterPro:   IPR011698
- TIGRFAMs:   TIGR00313

Pfam domain/function: PF01656 CbiA; PF07685 GATase_3

EC number: NA

Molecular weight: Translated: 55030; Mature: 55030

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: PS51274 GATASE_COBBQ

Important sites: ACT_SITE 338-338 ACT_SITE 439-439

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQHLRPIMFVGTCSDAGKSVINAAFCRIFKQDGYQPAPFKAQNMSLNSYSTPEGGEMGR
CCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCC
AQVVQAEACGISPHTDMNPILLKPTNDKSSQVVLNGKPVGNMSAKDYFGIQNQKEELFKE
CEEEEEHHCCCCCCCCCCCEEEECCCCCCCEEEECCCCCCCCCCCHHCCCCCHHHHHHHH
AIEAFKRLEARYNPIVLEGAGSISELNLRDRDITNMRMAIAAGASTYLVADIDRGGVFGS
HHHHHHHHHHCCCCEEEECCCCCEECCCCCCCCCCEEEEEECCCCEEEEEECCCCCEEEE
VYGTIALLRPEERVLMKGVIINKFRGDASLFEEGRSLLKELTGIPVVGVIPWFRDIKIEE
HHEEEEEECCHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHCCCEEEECCCHHCEEECC
EDSVALDMKNNTYKDGKINVAIILLKRMSNFTDFDVLEMDPRFNPYYTNNIDEIEKADII
CCCEEEEECCCCCCCCCEEEEEEEEEHHCCCCCCCEEEECCCCCCCCCCCCCHHCCCCEE
LLPGSKNTLSDLQSLRANGIAMAIIRAHKAGKKVIGICGGYQMMGVRLEDPESIEGNIPA
EECCCCCHHHHHHHHHHCCEEEEEEEHHHCCCEEEEEECCEEEEEEEECCCCCCCCCCCC
IPGLGLLPQCTVIEQEKITRQSDFAFLPSSENKDCKGYEIHMGRTTLLGDAPEQPVARLE
CCCCCCCCCCEEECHHHHCCCCCEEECCCCCCCCCCCEEEECCCEEEECCCCCCCHHHHC
DGRTDGYYLNNRCWGSYMHGILDNPAVLDNLAEGFDTETTTGPFDYAAFKEEQYDKLAAL
CCCCCCEEECCCCHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHH
VREHVDMEYIYNSIKN
HHHHCCHHHHHHHHCC
>Mature Secondary Structure
MKQHLRPIMFVGTCSDAGKSVINAAFCRIFKQDGYQPAPFKAQNMSLNSYSTPEGGEMGR
CCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCC
AQVVQAEACGISPHTDMNPILLKPTNDKSSQVVLNGKPVGNMSAKDYFGIQNQKEELFKE
CEEEEEHHCCCCCCCCCCCEEEECCCCCCCEEEECCCCCCCCCCCHHCCCCCHHHHHHHH
AIEAFKRLEARYNPIVLEGAGSISELNLRDRDITNMRMAIAAGASTYLVADIDRGGVFGS
HHHHHHHHHHCCCCEEEECCCCCEECCCCCCCCCCEEEEEECCCCEEEEEECCCCCEEEE
VYGTIALLRPEERVLMKGVIINKFRGDASLFEEGRSLLKELTGIPVVGVIPWFRDIKIEE
HHEEEEEECCHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHCCCEEEECCCHHCEEECC
EDSVALDMKNNTYKDGKINVAIILLKRMSNFTDFDVLEMDPRFNPYYTNNIDEIEKADII
CCCEEEEECCCCCCCCCEEEEEEEEEHHCCCCCCCEEEECCCCCCCCCCCCCHHCCCCEE
LLPGSKNTLSDLQSLRANGIAMAIIRAHKAGKKVIGICGGYQMMGVRLEDPESIEGNIPA
EECCCCCHHHHHHHHHHCCEEEEEEEHHHCCCEEEEEECCEEEEEEEECCCCCCCCCCCC
IPGLGLLPQCTVIEQEKITRQSDFAFLPSSENKDCKGYEIHMGRTTLLGDAPEQPVARLE
CCCCCCCCCCEEECHHHHCCCCCEEECCCCCCCCCCCEEEECCCEEEECCCCCCCHHHHC
DGRTDGYYLNNRCWGSYMHGILDNPAVLDNLAEGFDTETTTGPFDYAAFKEEQYDKLAAL
CCCCCCEEECCCCHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHH
VREHVDMEYIYNSIKN
HHHHCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA