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The map label for this gene is trpF

Identifier: 150006572

GI number: 150006572

Start: 5034640

End: 5035257

Strand: Direct

Name: trpF

Synonym: BVU_4092

Alternate gene names: 150006572

Gene position: 5034640-5035257 (Clockwise)

Preceding gene: 150006571

Following gene: 150006573

Centisome position: 97.51

GC content: 51.29

Gene sequence:

>618_bases
ATGATTATCAAGGTATGCGGTATGCGCGAGCCCGAAAACATACGCGCCATAGAGCAAGCCGGAGCAGACTGGATGGGCTT
CATCTTCTTCCCCCAATCTGCCCGCTACGTATCACATCGTCCGGAATACCTACCGGAACAATGCCACCGGATCGGGGTCT
TCGTCAACGAAAGCAGCGAAAACATCCTGCTGAAAGCACAGGAATTCGGTCTGCACCATATCCAATTGCATGGCAGGGAG
ACACCGGAACAATGCCGCAAATTAAAAGCCGCCGGACTGGGAGTCATTAAAGTTTTTTCCATAGCACAGGAAAGTGACCT
GCAATCCGCCGGTTGTTATGAGGGCGTTTGCGATTACTTTCTTTTCGACACTGCCTGCTCCGGATATGGCGGCTCCGGCA
AAACCTTCAACTGGAATATCCTGCAAGCCTATCGGGGAAAGACGCCTTTCCTGCTGAGTGGCGGTCTCCGTCCCGGCAGT
CTTTCCCTTTTGTTGCAATTCAAGCATGAACAATGGGCAGGTATCGACCTGAACAGCGGATTCGAGACCGCTCCGGCTCT
GAAAGACGACGCCGCCGTCCACACATTTATAAACCAATTAAAACAAAAAATACAATGA

Upstream 100 bases:

>100_bases
AGGCTTCCTGATAGGGGAAAACTTCATGAAAACACCCGCACCGGGAGAAGCCTTAAAAGAATTTATAACCCAACTAGAGA
AATGTTAGGATGAAGCAACA

Downstream 100 bases:

>100_bases
ACAGAATCAACCAGTTATTCAGTACCAAGCAAAAAGACATCCTATCTATTTATTTTTGTGCAGGCTTTCCTACCTTAGAA
GGTACGGCAAGCACCATCAA

Product: putative N-(5'-phosphoribosyl) anthranilate isomerase

Products: NA

Alternate protein names: PRAI

Number of amino acids: Translated: 205; Mature: 205

Protein sequence:

>205_residues
MIIKVCGMREPENIRAIEQAGADWMGFIFFPQSARYVSHRPEYLPEQCHRIGVFVNESSENILLKAQEFGLHHIQLHGRE
TPEQCRKLKAAGLGVIKVFSIAQESDLQSAGCYEGVCDYFLFDTACSGYGGSGKTFNWNILQAYRGKTPFLLSGGLRPGS
LSLLLQFKHEQWAGIDLNSGFETAPALKDDAAVHTFINQLKQKIQ

Sequences:

>Translated_205_residues
MIIKVCGMREPENIRAIEQAGADWMGFIFFPQSARYVSHRPEYLPEQCHRIGVFVNESSENILLKAQEFGLHHIQLHGRE
TPEQCRKLKAAGLGVIKVFSIAQESDLQSAGCYEGVCDYFLFDTACSGYGGSGKTFNWNILQAYRGKTPFLLSGGLRPGS
LSLLLQFKHEQWAGIDLNSGFETAPALKDDAAVHTFINQLKQKIQ
>Mature_205_residues
MIIKVCGMREPENIRAIEQAGADWMGFIFFPQSARYVSHRPEYLPEQCHRIGVFVNESSENILLKAQEFGLHHIQLHGRE
TPEQCRKLKAAGLGVIKVFSIAQESDLQSAGCYEGVCDYFLFDTACSGYGGSGKTFNWNILQAYRGKTPFLLSGGLRPGS
LSLLLQFKHEQWAGIDLNSGFETAPALKDDAAVHTFINQLKQKIQ

Specific function: Bifunctional Enzyme That Catalyzes Two Sequential Steps Of Tryptophan Biosynthetic Pathway. The First Reaction Is Catalyzed By The Isomerase, Coded By The Trpf Domain; The Second Reaction Is Catalyzed By The Synthase, Coded By The Trpc Domain. [C]

COG id: COG0135

COG function: function code E; Phosphoribosylanthranilate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpF family

Homologues:

Organism=Escherichia coli, GI87081863, Length=189, Percent_Identity=29.1005291005291, Blast_Score=70, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6320210, Length=226, Percent_Identity=25.6637168141593, Blast_Score=75, Evalue=6e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): TRPF_BACV8 (A6L7N0)

Other databases:

- EMBL:   CP000139
- RefSeq:   YP_001301316.1
- ProteinModelPortal:   A6L7N0
- SMR:   A6L7N0
- STRING:   A6L7N0
- GeneID:   5305051
- GenomeReviews:   CP000139_GR
- KEGG:   bvu:BVU_4092
- NMPDR:   fig|435590.6.peg.3805
- eggNOG:   COG0135
- HOGENOM:   HBG554803
- OMA:   IQLHGRE
- ProtClustDB:   CLSK822228
- HAMAP:   MF_00135_B
- InterPro:   IPR013785
- InterPro:   IPR001240
- InterPro:   IPR011060
- Gene3D:   G3DSA:3.20.20.70

Pfam domain/function: PF00697 PRAI; SSF51366 RibP_bind_barrel

EC number: =5.3.1.24

Molecular weight: Translated: 22897; Mature: 22897

Theoretical pI: Translated: 7.15; Mature: 7.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIKVCGMREPENIRAIEQAGADWMGFIFFPQSARYVSHRPEYLPEQCHRIGVFVNESSE
CEEEECCCCCCHHHHHHHHCCCCEEEEEEECCCCCHHHCCCCCCHHHHHHEEEEEECCCC
NILLKAQEFGLHHIQLHGRETPEQCRKLKAAGLGVIKVFSIAQESDLQSAGCYEGVCDYF
CEEEEEHHCCEEEEEECCCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCHHHHHHHH
LFDTACSGYGGSGKTFNWNILQAYRGKTPFLLSGGLRPGSLSLLLQFKHEQWAGIDLNSG
HHHHHCCCCCCCCCEEEEEEHHHHCCCCCEEEECCCCCCCEEEEEEECCCCCCCCCCCCC
FETAPALKDDAAVHTFINQLKQKIQ
CCCCCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIIKVCGMREPENIRAIEQAGADWMGFIFFPQSARYVSHRPEYLPEQCHRIGVFVNESSE
CEEEECCCCCCHHHHHHHHCCCCEEEEEEECCCCCHHHCCCCCCHHHHHHEEEEEECCCC
NILLKAQEFGLHHIQLHGRETPEQCRKLKAAGLGVIKVFSIAQESDLQSAGCYEGVCDYF
CEEEEEHHCCEEEEEECCCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCHHHHHHHH
LFDTACSGYGGSGKTFNWNILQAYRGKTPFLLSGGLRPGSLSLLLQFKHEQWAGIDLNSG
HHHHHCCCCCCCCCEEEEEEHHHHCCCCCEEEECCCCCCCEEEEEEECCCCCCCCCCCCC
FETAPALKDDAAVHTFINQLKQKIQ
CCCCCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA