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The map label for this gene is rfbC [H]

Identifier: 150004940

GI number: 150004940

Start: 3087161

End: 3087733

Strand: Direct

Name: rfbC [H]

Synonym: BVU_2403

Alternate gene names: 150004940

Gene position: 3087161-3087733 (Clockwise)

Preceding gene: 150004939

Following gene: 150004941

Centisome position: 59.79

GC content: 43.28

Gene sequence:

>573_bases
ATGGAGGTTATAAAAACAGGAATAGAAGGTGTGGTGGTCATTGAACCGCGCATCTTTAAAGATGAAAGAGGCTATTTCTT
TGAATCTTTTTCTCAACGGGAGTTTAATGAAAAGGTGATGCCTGTCAATTTTGTACAGGATAATGAGAGTATGTCATCGT
ATGGCGTGATGCGTGGGTTACATTTTCAGCAAATGCCTTATACTCAGAGCAAGCTGGTGCGTTGTGTAAAAGGTGCCGTA
CTTGATGTGGCGGTAGACATCCGCAAGGGAAGTCCTACATACGGGCAGCATGTTGCGGTGGAATTGACGGAGGAAAACCA
TCTCCAATTCTTTATCCCCCGTGGATTTGCCCATGGTTTTGCCGTATTGAGTGAAACAGCGGTTTTTCAATATAAGTGCG
ATAACTTCTATGCACCGCAAGCTGATGGTGGCATTCAGCTGCGCGATGAAAGTCTGGGTATTGATTGGAAAATACCCGTT
GCCGAGGCCATTTTAAGTGAGAAGGATTTGAAACATCCTTTGTTGAAAGACTATGACTCTCCGTTTGACTACACTATTAA
TCTATACGAATGA

Upstream 100 bases:

>100_bases
TGACCTTGCCAAACCGATGCTGAAAAACCAATACGGTCAGTATCTGCTCAAAGTGATTGATGAAGTGGAACGTACAGGCA
AAGAAAATCTAGATTAAGAT

Downstream 100 bases:

>100_bases
TGAATATACTTGTTACAGGTGCCAATGGTCAACTTGGCAATGAGATGCGCAGGGTGTCGTTAGACAGCCGGAATCGTTAT
CTCTTTACAGATGTAAATGA

Product: dTDP-4-dehydrorhamnose 3,5-epimerase

Products: NA

Alternate protein names: Thymidine diphospho-4-keto-rhamnose 3,5-epimerase; dTDP-4-keto-6-deoxyglucose 3,5-epimerase; dTDP-6-deoxy-D-xylo-4-hexulose 3,5-epimerase; dTDP-L-rhamnose synthase [H]

Number of amino acids: Translated: 190; Mature: 190

Protein sequence:

>190_residues
MEVIKTGIEGVVVIEPRIFKDERGYFFESFSQREFNEKVMPVNFVQDNESMSSYGVMRGLHFQQMPYTQSKLVRCVKGAV
LDVAVDIRKGSPTYGQHVAVELTEENHLQFFIPRGFAHGFAVLSETAVFQYKCDNFYAPQADGGIQLRDESLGIDWKIPV
AEAILSEKDLKHPLLKDYDSPFDYTINLYE

Sequences:

>Translated_190_residues
MEVIKTGIEGVVVIEPRIFKDERGYFFESFSQREFNEKVMPVNFVQDNESMSSYGVMRGLHFQQMPYTQSKLVRCVKGAV
LDVAVDIRKGSPTYGQHVAVELTEENHLQFFIPRGFAHGFAVLSETAVFQYKCDNFYAPQADGGIQLRDESLGIDWKIPV
AEAILSEKDLKHPLLKDYDSPFDYTINLYE
>Mature_190_residues
MEVIKTGIEGVVVIEPRIFKDERGYFFESFSQREFNEKVMPVNFVQDNESMSSYGVMRGLHFQQMPYTQSKLVRCVKGAV
LDVAVDIRKGSPTYGQHVAVELTEENHLQFFIPRGFAHGFAVLSETAVFQYKCDNFYAPQADGGIQLRDESLGIDWKIPV
AEAILSEKDLKHPLLKDYDSPFDYTINLYE

Specific function: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose [H]

COG id: COG1898

COG function: function code M; dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI1788350, Length=170, Percent_Identity=54.7058823529412, Blast_Score=186, Evalue=8e-49,
Organism=Caenorhabditis elegans, GI17550412, Length=178, Percent_Identity=47.1910112359551, Blast_Score=142, Evalue=1e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR000888
- InterPro:   IPR014710
- ProDom:   PD001462 [H]

Pfam domain/function: PF00908 dTDP_sugar_isom [H]

EC number: =5.1.3.13 [H]

Molecular weight: Translated: 21745; Mature: 21745

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEVIKTGIEGVVVIEPRIFKDERGYFFESFSQREFNEKVMPVNFVQDNESMSSYGVMRGL
CCCCCCCCCEEEEECCEEEECCCCCHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHCC
HFQQMPYTQSKLVRCVKGAVLDVAVDIRKGSPTYGQHVAVELTEENHLQFFIPRGFAHGF
CCCCCCCCHHHHHHHHHCCEEEEEEEEECCCCCCCCEEEEEEECCCCEEEEEECCCHHHH
AVLSETAVFQYKCDNFYAPQADGGIQLRDESLGIDWKIPVAEAILSEKDLKHPLLKDYDS
HHHHHCEEEEEECCCEECCCCCCCEEEEECCCCCEEECHHHHHHHHHHHCCCCHHHCCCC
PFDYTINLYE
CCCEEEEEEC
>Mature Secondary Structure
MEVIKTGIEGVVVIEPRIFKDERGYFFESFSQREFNEKVMPVNFVQDNESMSSYGVMRGL
CCCCCCCCCEEEEECCEEEECCCCCHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHCC
HFQQMPYTQSKLVRCVKGAVLDVAVDIRKGSPTYGQHVAVELTEENHLQFFIPRGFAHGF
CCCCCCCCHHHHHHHHHCCEEEEEEEEECCCCCCCCEEEEEEECCCCEEEEEECCCHHHH
AVLSETAVFQYKCDNFYAPQADGGIQLRDESLGIDWKIPVAEAILSEKDLKHPLLKDYDS
HHHHHCEEEEEECCCEECCCCCCCEEEEECCCCCEEECHHHHHHHHHHHCCCCHHHCCCC
PFDYTINLYE
CCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8170390; 8157605; 12384590; 12704152 [H]