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The map label for this gene is rmlA [H]

Identifier: 150004939

GI number: 150004939

Start: 3086252

End: 3087157

Strand: Direct

Name: rmlA [H]

Synonym: BVU_2402

Alternate gene names: 150004939

Gene position: 3086252-3087157 (Clockwise)

Preceding gene: 150004938

Following gene: 150004940

Centisome position: 59.77

GC content: 45.92

Gene sequence:

>906_bases
ATGAAAGGAATTGTTCTCGCCGGTGGTAGCGGTACCCGTCTGTACCCCATCACCAAGGGAGTAAGCAAGCAGCTTCTCCC
CATCTTTGACAAACCGATGATTTACTACCCTATTTCAGTCTTGATGCTGGCAGGCATCCGTGAGATTCTGATTATATCCA
CTCCCTATGATCTGCCCGGCTTTAAGCGTCTTTTGGGCGATGGATCAGACTATGGTGTGAAGTTCGAGTATGCCGAACAA
CCTTCTCCCGATGGTCTTGCACAAGCCTTTATTATCGGAGAGAAATTCATTGGTAATGATTCTGCATGTTTGGTATTAGG
CGACAATATCTTCCATGGTAACGGTTTCAGTTCTCTTCTTCGTGAAGCCGTGCGTATGGCGGAAGAAGAACAAAAAGCTA
CTGTATTCGGTTACTGGGTGAACGATCCGGAACGTTATGGTGTGGCAGAATTTGATGTGGAAGGTAACTGCCTGAGCATC
GAAGAAAAACCGGAACAGCCCAAATCAAATTATGCAGTGGTGGGCCTCTATTTTTATCCCAACAAAGTAGTGGAAGTGGC
CAAGAACATCAAACCTTCCGCACGTGGCGAACTGGAAATAACGACAGTGAACCAGCGTTTTCTGGAAGATCGTGAACTGA
AAGTACAGACGTTGGGACGCGGTTTTGCCTGGCTGGATACGGGAACGCATGATTCATTGGCAGAAGCTTCGACTTATATA
GAAGTCATTGAAAAACGTCAGGGTTTGAAAGTGGCTTGTCTGGAAGGAATTGCTTATCGCAAAGGCTGGATAACGGCAGA
TAAGATGCGTGACCTTGCCAAACCGATGCTGAAAAACCAATACGGTCAGTATCTGCTCAAAGTGATTGATGAAGTGGAAC
GTACAGGCAAAGAAAATCTAGATTAA

Upstream 100 bases:

>100_bases
TTATATTAATGCTGTGGTAGAAATGACAGAATGTAAGCATTTGTCAGGCGGAGTGATATTTAAAGTACATTTAAAATAAC
AAACACTATAACTTATTCGT

Downstream 100 bases:

>100_bases
GATATGGAGGTTATAAAAACAGGAATAGAAGGTGTGGTGGTCATTGAACCGCGCATCTTTAAAGATGAAAGAGGCTATTT
CTTTGAATCTTTTTCTCAAC

Product: glucose-1-phosphate thymidyltransferase

Products: NA

Alternate protein names: dTDP-glucose pyrophosphorylase; dTDP-glucose synthase [H]

Number of amino acids: Translated: 301; Mature: 301

Protein sequence:

>301_residues
MKGIVLAGGSGTRLYPITKGVSKQLLPIFDKPMIYYPISVLMLAGIREILIISTPYDLPGFKRLLGDGSDYGVKFEYAEQ
PSPDGLAQAFIIGEKFIGNDSACLVLGDNIFHGNGFSSLLREAVRMAEEEQKATVFGYWVNDPERYGVAEFDVEGNCLSI
EEKPEQPKSNYAVVGLYFYPNKVVEVAKNIKPSARGELEITTVNQRFLEDRELKVQTLGRGFAWLDTGTHDSLAEASTYI
EVIEKRQGLKVACLEGIAYRKGWITADKMRDLAKPMLKNQYGQYLLKVIDEVERTGKENLD

Sequences:

>Translated_301_residues
MKGIVLAGGSGTRLYPITKGVSKQLLPIFDKPMIYYPISVLMLAGIREILIISTPYDLPGFKRLLGDGSDYGVKFEYAEQ
PSPDGLAQAFIIGEKFIGNDSACLVLGDNIFHGNGFSSLLREAVRMAEEEQKATVFGYWVNDPERYGVAEFDVEGNCLSI
EEKPEQPKSNYAVVGLYFYPNKVVEVAKNIKPSARGELEITTVNQRFLEDRELKVQTLGRGFAWLDTGTHDSLAEASTYI
EVIEKRQGLKVACLEGIAYRKGWITADKMRDLAKPMLKNQYGQYLLKVIDEVERTGKENLD
>Mature_301_residues
MKGIVLAGGSGTRLYPITKGVSKQLLPIFDKPMIYYPISVLMLAGIREILIISTPYDLPGFKRLLGDGSDYGVKFEYAEQ
PSPDGLAQAFIIGEKFIGNDSACLVLGDNIFHGNGFSSLLREAVRMAEEEQKATVFGYWVNDPERYGVAEFDVEGNCLSI
EEKPEQPKSNYAVVGLYFYPNKVVEVAKNIKPSARGELEITTVNQRFLEDRELKVQTLGRGFAWLDTGTHDSLAEASTYI
EVIEKRQGLKVACLEGIAYRKGWITADKMRDLAKPMLKNQYGQYLLKVIDEVERTGKENLD

Specific function: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis [H]

COG id: COG1209

COG function: function code M; dTDP-glucose pyrophosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucose-1-phosphate thymidylyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1790224, Length=289, Percent_Identity=66.7820069204152, Blast_Score=400, Evalue=1e-113,
Organism=Escherichia coli, GI1788351, Length=290, Percent_Identity=65.8620689655172, Blast_Score=395, Evalue=1e-111,
Organism=Escherichia coli, GI1787488, Length=247, Percent_Identity=25.1012145748988, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788355, Length=236, Percent_Identity=26.271186440678, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI133931050, Length=187, Percent_Identity=26.2032085561497, Blast_Score=67, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6320148, Length=257, Percent_Identity=28.4046692607004, Blast_Score=77, Evalue=4e-15,
Organism=Drosophila melanogaster, GI21355443, Length=256, Percent_Identity=24.21875, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24644084, Length=256, Percent_Identity=24.21875, Blast_Score=72, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005907
- InterPro:   IPR005835 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.24 [H]

Molecular weight: Translated: 33624; Mature: 33624

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGIVLAGGSGTRLYPITKGVSKQLLPIFDKPMIYYPISVLMLAGIREILIISTPYDLPG
CCCEEEECCCCCEEEEECCCCCHHHHHHHCCCCHHHHHHHHHHHCCCEEEEEECCCCCCH
FKRLLGDGSDYGVKFEYAEQPSPDGLAQAFIIGEKFIGNDSACLVLGDNIFHGNGFSSLL
HHHHHCCCCCCCEEEEECCCCCCCHHHHHHEECHHHCCCCCEEEEEECCEECCCCHHHHH
REAVRMAEEEQKATVFGYWVNDPERYGVAEFDVEGNCLSIEEKPEQPKSNYAVVGLYFYP
HHHHHHHHHCCCEEEEEEECCCCHHCCCEEEECCCCEEECCCCCCCCCCCEEEEEEEECC
NKVVEVAKNIKPSARGELEITTVNQRFLEDRELKVQTLGRGFAWLDTGTHDSLAEASTYI
HHHHHHHHCCCCCCCCCEEEEECCHHHHCCCCEEEEHHCCCEEEEECCCCHHHHHHHHHH
EVIEKRQGLKVACLEGIAYRKGWITADKMRDLAKPMLKNQYGQYLLKVIDEVERTGKENL
HHHHHCCCCEEEEHHCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
D
C
>Mature Secondary Structure
MKGIVLAGGSGTRLYPITKGVSKQLLPIFDKPMIYYPISVLMLAGIREILIISTPYDLPG
CCCEEEECCCCCEEEEECCCCCHHHHHHHCCCCHHHHHHHHHHHCCCEEEEEECCCCCCH
FKRLLGDGSDYGVKFEYAEQPSPDGLAQAFIIGEKFIGNDSACLVLGDNIFHGNGFSSLL
HHHHHCCCCCCCEEEEECCCCCCCHHHHHHEECHHHCCCCCEEEEEECCEECCCCHHHHH
REAVRMAEEEQKATVFGYWVNDPERYGVAEFDVEGNCLSIEEKPEQPKSNYAVVGLYFYP
HHHHHHHHHCCCEEEEEEECCCCHHCCCEEEECCCCEEECCCCCCCCCCCEEEEEEEECC
NKVVEVAKNIKPSARGELEITTVNQRFLEDRELKVQTLGRGFAWLDTGTHDSLAEASTYI
HHHHHHHHCCCCCCCCCEEEEECCHHHHCCCCEEEEHHCCCEEEEECCCCHHHHHHHHHH
EVIEKRQGLKVACLEGIAYRKGWITADKMRDLAKPMLKNQYGQYLLKVIDEVERTGKENL
HHHHHCCCCEEEEHHCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
D
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12397186 [H]