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The map label for this gene is wzb [C]

Identifier: 150004038

GI number: 150004038

Start: 1951995

End: 1952465

Strand: Direct

Name: wzb [C]

Synonym: BVU_1473

Alternate gene names: 150004038

Gene position: 1951995-1952465 (Clockwise)

Preceding gene: 150004037

Following gene: 150004040

Centisome position: 37.81

GC content: 48.41

Gene sequence:

>471_bases
ATGAAAAGAATACTTTTTGTCTGCCTCGGTAACATTTGCAGGTCTTCTTCGGCAGAAGAAGTGATGCGTACTCTCATAAA
GAAAAAAGGACTGGAACACGAGATAGAGGTGGATTCTGCCGGAATCCTGAGTTATCATAGAGGGGAATTGCCCGACAGCC
GTATGCGGATGCATGCTTCCCGCCGCGGTTACAATCTGACCCATCGTTCCCGTCCTGTCTGTACGGAGGATTTCTATCAT
TTTGATATGATCATCGGCATGGACGACCGTAATATAGAGGACCTGATGGAGCGTGCTCCCGATCTGGAAACGGAAAAGAA
AATCCATCGCATGACGGATTATTGCCGCACCAAAGTGGCAGACTATGTTCCCGACCCTTACTATGGCGGTGCGCAAGGGT
TCGAGAACGTGCTTGATATACTGGAAGATGCTTGTGCAGGATTGCTTACTTCCTTAGTTCCGGGTAACTGA

Upstream 100 bases:

>100_bases
AATTTGTATGAATTGTTGCAGCTTACCGGGTTTCCTGAAGAGCTGATCATGAACCGTGATGTGAAATCATTTAAAGAATA
CCTTCATTTGTAGATTATAT

Downstream 100 bases:

>100_bases
TTCGGGTGTGATACATCGTTTTCAGCTTTTCTTTAAACAGTGCTTTGACTGTTGCTATATCCTTGAACGTAATAGGGCAT
TCTTTGAAATACCCCTCAGA

Product: putative protein-tyrosine-phosphatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 156; Mature: 156

Protein sequence:

>156_residues
MKRILFVCLGNICRSSSAEEVMRTLIKKKGLEHEIEVDSAGILSYHRGELPDSRMRMHASRRGYNLTHRSRPVCTEDFYH
FDMIIGMDDRNIEDLMERAPDLETEKKIHRMTDYCRTKVADYVPDPYYGGAQGFENVLDILEDACAGLLTSLVPGN

Sequences:

>Translated_156_residues
MKRILFVCLGNICRSSSAEEVMRTLIKKKGLEHEIEVDSAGILSYHRGELPDSRMRMHASRRGYNLTHRSRPVCTEDFYH
FDMIIGMDDRNIEDLMERAPDLETEKKIHRMTDYCRTKVADYVPDPYYGGAQGFENVLDILEDACAGLLTSLVPGN
>Mature_156_residues
MKRILFVCLGNICRSSSAEEVMRTLIKKKGLEHEIEVDSAGILSYHRGELPDSRMRMHASRRGYNLTHRSRPVCTEDFYH
FDMIIGMDDRNIEDLMERAPDLETEKKIHRMTDYCRTKVADYVPDPYYGGAQGFENVLDILEDACAGLLTSLVPGN

Specific function: Dephosphorylates Wzc. Required For The Extracellular Polysaccharide Colanic Acid Synthesis. Probably Involved In The Export Of Colanic Acid From The Cell To Medium. [C]

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase family [H]

Homologues:

Organism=Homo sapiens, GI4757714, Length=149, Percent_Identity=38.255033557047, Blast_Score=98, Evalue=3e-21,
Organism=Homo sapiens, GI6005988, Length=149, Percent_Identity=35.5704697986577, Blast_Score=95, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6325330, Length=135, Percent_Identity=34.8148148148148, Blast_Score=89, Evalue=3e-19,
Organism=Drosophila melanogaster, GI78706766, Length=150, Percent_Identity=36, Blast_Score=93, Evalue=7e-20,
Organism=Drosophila melanogaster, GI78706768, Length=150, Percent_Identity=36, Blast_Score=93, Evalue=7e-20,
Organism=Drosophila melanogaster, GI78706770, Length=147, Percent_Identity=36.0544217687075, Blast_Score=90, Evalue=6e-19,
Organism=Drosophila melanogaster, GI78706772, Length=147, Percent_Identity=36.0544217687075, Blast_Score=90, Evalue=6e-19,
Organism=Drosophila melanogaster, GI78711846, Length=144, Percent_Identity=36.1111111111111, Blast_Score=89, Evalue=1e-18,
Organism=Drosophila melanogaster, GI78706764, Length=128, Percent_Identity=35.9375, Blast_Score=83, Evalue=6e-17,
Organism=Drosophila melanogaster, GI24648069, Length=101, Percent_Identity=36.6336633663366, Blast_Score=70, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000106
- InterPro:   IPR017867 [H]

Pfam domain/function: PF01451 LMWPc [H]

EC number: =3.1.3.48 [H]

Molecular weight: Translated: 17874; Mature: 17874

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
8.3 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
8.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRILFVCLGNICRSSSAEEVMRTLIKKKGLEHEIEVDSAGILSYHRGELPDSRMRMHAS
CCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEECCCCCCHHHHHCCCCCHHHHHHHHH
RRGYNLTHRSRPVCTEDFYHFDMIIGMDDRNIEDLMERAPDLETEKKIHRMTDYCRTKVA
HCCCCCCCCCCCCCCHHHHHHHEEECCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
DYVPDPYYGGAQGFENVLDILEDACAGLLTSLVPGN
HHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKRILFVCLGNICRSSSAEEVMRTLIKKKGLEHEIEVDSAGILSYHRGELPDSRMRMHAS
CCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEECCCCCCHHHHHCCCCCHHHHHHHHH
RRGYNLTHRSRPVCTEDFYHFDMIIGMDDRNIEDLMERAPDLETEKKIHRMTDYCRTKVA
HCCCCCCCCCCCCCCHHHHHHHEEECCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
DYVPDPYYGGAQGFENVLDILEDACAGLLTSLVPGN
HHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]