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The map label for this gene is purE [H]

Identifier: 150003982

GI number: 150003982

Start: 1892590

End: 1893099

Strand: Reverse

Name: purE [H]

Synonym: BVU_1416

Alternate gene names: 150003982

Gene position: 1893099-1892590 (Counterclockwise)

Preceding gene: 150003983

Following gene: 150003981

Centisome position: 36.67

GC content: 46.08

Gene sequence:

>510_bases
ATGAAACCTATCGTAAGCATTATCATGGGTAGCACTTCCGATCTTCCCGTAATGGAAAAAGCTGCCAAATTACTGGACGA
GATGCACGTACCTTTCGAAATGAACGCCCTTTCGGCACACCGCACTCCCGAAGCTGTGGAGGAATTTGCGAAAAATGCTG
CAGGCCGTGGAATTAAAGTCATCATTGCCGCTGCCGGCATGGCTGCCGCACTTCCCGGTGTCATTGCTGCAAATACCACA
TTGCCTGTTATCGGTGTCCCCGTTAAAGGTTCAGTTCTTGATGGCGTAGACGCACTTTATTCTATCATCCAAATGCCTCC
CGGAATTCCTGTAGCTACCGTAGCAATCAATGGAGCCATGAATGCAGCTATTCTGGCCGTACAAATGCTAGCATTGAGTG
ATACAGAACTAGCCACCAAGTTTGCAGACTACAAGACCGGCTTGAAAAAGAAAATCGTGAAAGCCAACGAAGAACTGAAA
GAAGTCAAGTTTGAATATAAAACAAATTAA

Upstream 100 bases:

>100_bases
CAAGCGCGGATTACGCGGACCTCACGGATTTTTCTATCCGCGTTCATCCGTATAACCCGTGCTTGAAGTAAATATATAAA
CCAAACAATAACAAAAAACA

Downstream 100 bases:

>100_bases
CTAGTGGTTAGTGATTAGTGGTAAGTGGTTAATATTTCAGCGCAGCCCACTAATCACTAACCACTCACCACTAATCACTA
ACTATGGATTTATTCAATTA

Product: phosphoribosylaminoimidazole carboxylase

Products: NA

Alternate protein names: N5-CAIR mutase; 5-(carboxyamino)imidazole ribonucleotide mutase [H]

Number of amino acids: Translated: 169; Mature: 169

Protein sequence:

>169_residues
MKPIVSIIMGSTSDLPVMEKAAKLLDEMHVPFEMNALSAHRTPEAVEEFAKNAAGRGIKVIIAAAGMAAALPGVIAANTT
LPVIGVPVKGSVLDGVDALYSIIQMPPGIPVATVAINGAMNAAILAVQMLALSDTELATKFADYKTGLKKKIVKANEELK
EVKFEYKTN

Sequences:

>Translated_169_residues
MKPIVSIIMGSTSDLPVMEKAAKLLDEMHVPFEMNALSAHRTPEAVEEFAKNAAGRGIKVIIAAAGMAAALPGVIAANTT
LPVIGVPVKGSVLDGVDALYSIIQMPPGIPVATVAINGAMNAAILAVQMLALSDTELATKFADYKTGLKKKIVKANEELK
EVKFEYKTN
>Mature_169_residues
MKPIVSIIMGSTSDLPVMEKAAKLLDEMHVPFEMNALSAHRTPEAVEEFAKNAAGRGIKVIIAAAGMAAALPGVIAANTT
LPVIGVPVKGSVLDGVDALYSIIQMPPGIPVATVAINGAMNAAILAVQMLALSDTELATKFADYKTGLKKKIVKANEELK
EVKFEYKTN

Specific function: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) [H]

COG id: COG0041

COG function: function code F; Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AIR carboxylase family [H]

Homologues:

Organism=Escherichia coli, GI1786734, Length=152, Percent_Identity=44.7368421052632, Blast_Score=121, Evalue=3e-29,
Organism=Saccharomyces cerevisiae, GI6324702, Length=165, Percent_Identity=53.9393939393939, Blast_Score=176, Evalue=2e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000031 [H]

Pfam domain/function: PF00731 AIRC [H]

EC number: =5.4.99.18 [H]

Molecular weight: Translated: 17744; Mature: 17744

Theoretical pI: Translated: 7.67; Mature: 7.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.3 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPIVSIIMGSTSDLPVMEKAAKLLDEMHVPFEMNALSAHRTPEAVEEFAKNAAGRGIKV
CCHHHHHHHCCCCCCHHHHHHHHHHHHHCCCEECCCCCCCCCHHHHHHHHHHCCCCCEEE
IIAAAGMAAALPGVIAANTTLPVIGVPVKGSVLDGVDALYSIIQMPPGIPVATVAINGAM
EEEHHHHHHHHCCCEECCCCCCEEECCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCHH
NAAILAVQMLALSDTELATKFADYKTGLKKKIVKANEELKEVKFEYKTN
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKPIVSIIMGSTSDLPVMEKAAKLLDEMHVPFEMNALSAHRTPEAVEEFAKNAAGRGIKV
CCHHHHHHHCCCCCCHHHHHHHHHHHHHCCCEECCCCCCCCCHHHHHHHHHHCCCCCEEE
IIAAAGMAAALPGVIAANTTLPVIGVPVKGSVLDGVDALYSIIQMPPGIPVATVAINGAM
EEEHHHHHHHHCCCEECCCCCCEEECCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCHH
NAAILAVQMLALSDTELATKFADYKTGLKKKIVKANEELKEVKFEYKTN
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12622808 [H]