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The map label for this gene is atsA [H]

Identifier: 150003729

GI number: 150003729

Start: 1572974

End: 1574500

Strand: Direct

Name: atsA [H]

Synonym: BVU_1160

Alternate gene names: 150003729

Gene position: 1572974-1574500 (Clockwise)

Preceding gene: 150003728

Following gene: 150003730

Centisome position: 30.47

GC content: 41.98

Gene sequence:

>1527_bases
ATGAAAAATCGAAACCTCTTTCTTTTAACCAGTGGGCTGGCATTTCCTTTATTAGGTGCTTATGCCCAGAAAACCCCTAA
ACCGAATATCATTTATATAATGTGTGATGATATGGGGTATGGTGATTTAGGGTGTTACGGTCAGCCCTACATCAGTACAC
CGAATATTGATAATATGGCTAAAGAAGGTATGCGTTTTACACAAGCGTATGCCGGTAGTCCGGTGAGTGCTCCATCACGT
GCGTCATTTATGACCGGGCAACATTCCGGACATTGTGAAGTACGTGGGAACAAGGAGTACTGGCGCGATGCCCCTGTTGT
GATGTATGGAAATAATAAGGAATATGCCGTGGTGGGGCAACATCCATACGATCCCGGTCATGTGATTATACCTGAAATAA
TGAAAGATAACGGTTATACTACCGGTATGTTTGGTAAATGGGCAGGGGGCTATGAGGGATCTGTGTCTACGCCGGACAAA
CGGGGTATTGATGAATATTATGGTTATATCTGTCAGTTTCAGGCTCATTTATATTATCCGAATTTCCTGAACCGGTATAG
TAAATCGGCTGGTGATACGGCAGTGGTTCGTGTAGTGATGGATGAGAATATCAACTATCCTATGTTTGGTAAGGACTATT
TCAAACGTCCGCAATATTCTGCGGATATGATCCATGAAGAAGCAATGAAATGGTTGGATAAACAGGATGGCAAGCAACCT
TTCTTTGGTATTTTTACTTATACGCTTCCTCATGCAGAGCTGGCGCAGCCCGAAGATTCTATTCTGACAGGTTATCAAAA
GAAGTTTTTTGAAGATAAAACTTGGGGTGGACAGGAAGGATCAAGATATAATCCGTCGGTACACACCCATGCGCAGTTTG
CCGGCATGATTACTCGCTTGGATTATTATGTAGGAGAAGTTTTGAACAAATTAAAGGAGAAAGGACTGGACGAAAATACC
ATTGTGATTTTTACCAGTGATAACGGCCCTCATGAAGAAGGAGGAGCTGATCCTACCTTTTTTGGTCGTGACGGCAAACT
TCGTGGATTGAAACGTCAATGTTATGAGGGAGGTATCCGTATTCCGTTCATTGTACGTTGGCCGGGCAAAGTACCCGAAG
GAACGGTCAATGATCATCAGTTGGCTTTCTATGACTTGATGCCTACATTTTGTGACTTGGCAGGTGTGAAGAATTATGTA
AAGAAGTACACTAACAAGAAAAAAGATGTGGATTATTTTGATGGTATTTCTTTTGCTCCGACTTTGTTAGGGCAGGAAGG
ACAGAAGAAACATGATTTCTTGTATTGGGAATTTGATGAAACCGATCAGATTGGTGTACGTATGGGAGACTGGAAGATGG
TAGTGAAAAAAGGGACTCCTTTCCTTTACAATCTTGCTACAGATATTCATGAAGACCATGATATCGCTGCCGGACATCCG
GATATTGTGAAACAAATGAAAGAGATTATCAGAACACAGCATACTCCGAATCCTCATTTCTCTGTGACTTTGCCTTCATT
TGAATAA

Upstream 100 bases:

>100_bases
TTTTTTTCTTCTATAGCTTTGCAGCCTAGGATATTTTCTCTAAATTGCCGATGTTTATAGCAGGAGTAGTAATTATTAAA
TTCAGTAAAAAACAGAATAT

Downstream 100 bases:

>100_bases
ATAGATTTTTTATTCTGATATTCCTCAATCTATTCATTTAGATTGAGGAATATTTTTTTATGTTCCATAAACCTGCTATC
TTTGTCTCGCAAATTTAAAA

Product: arylsulfatase precursor

Products: NA

Alternate protein names: AS; Aryl-sulfate sulphohydrolase [H]

Number of amino acids: Translated: 508; Mature: 508

Protein sequence:

>508_residues
MKNRNLFLLTSGLAFPLLGAYAQKTPKPNIIYIMCDDMGYGDLGCYGQPYISTPNIDNMAKEGMRFTQAYAGSPVSAPSR
ASFMTGQHSGHCEVRGNKEYWRDAPVVMYGNNKEYAVVGQHPYDPGHVIIPEIMKDNGYTTGMFGKWAGGYEGSVSTPDK
RGIDEYYGYICQFQAHLYYPNFLNRYSKSAGDTAVVRVVMDENINYPMFGKDYFKRPQYSADMIHEEAMKWLDKQDGKQP
FFGIFTYTLPHAELAQPEDSILTGYQKKFFEDKTWGGQEGSRYNPSVHTHAQFAGMITRLDYYVGEVLNKLKEKGLDENT
IVIFTSDNGPHEEGGADPTFFGRDGKLRGLKRQCYEGGIRIPFIVRWPGKVPEGTVNDHQLAFYDLMPTFCDLAGVKNYV
KKYTNKKKDVDYFDGISFAPTLLGQEGQKKHDFLYWEFDETDQIGVRMGDWKMVVKKGTPFLYNLATDIHEDHDIAAGHP
DIVKQMKEIIRTQHTPNPHFSVTLPSFE

Sequences:

>Translated_508_residues
MKNRNLFLLTSGLAFPLLGAYAQKTPKPNIIYIMCDDMGYGDLGCYGQPYISTPNIDNMAKEGMRFTQAYAGSPVSAPSR
ASFMTGQHSGHCEVRGNKEYWRDAPVVMYGNNKEYAVVGQHPYDPGHVIIPEIMKDNGYTTGMFGKWAGGYEGSVSTPDK
RGIDEYYGYICQFQAHLYYPNFLNRYSKSAGDTAVVRVVMDENINYPMFGKDYFKRPQYSADMIHEEAMKWLDKQDGKQP
FFGIFTYTLPHAELAQPEDSILTGYQKKFFEDKTWGGQEGSRYNPSVHTHAQFAGMITRLDYYVGEVLNKLKEKGLDENT
IVIFTSDNGPHEEGGADPTFFGRDGKLRGLKRQCYEGGIRIPFIVRWPGKVPEGTVNDHQLAFYDLMPTFCDLAGVKNYV
KKYTNKKKDVDYFDGISFAPTLLGQEGQKKHDFLYWEFDETDQIGVRMGDWKMVVKKGTPFLYNLATDIHEDHDIAAGHP
DIVKQMKEIIRTQHTPNPHFSVTLPSFE
>Mature_508_residues
MKNRNLFLLTSGLAFPLLGAYAQKTPKPNIIYIMCDDMGYGDLGCYGQPYISTPNIDNMAKEGMRFTQAYAGSPVSAPSR
ASFMTGQHSGHCEVRGNKEYWRDAPVVMYGNNKEYAVVGQHPYDPGHVIIPEIMKDNGYTTGMFGKWAGGYEGSVSTPDK
RGIDEYYGYICQFQAHLYYPNFLNRYSKSAGDTAVVRVVMDENINYPMFGKDYFKRPQYSADMIHEEAMKWLDKQDGKQP
FFGIFTYTLPHAELAQPEDSILTGYQKKFFEDKTWGGQEGSRYNPSVHTHAQFAGMITRLDYYVGEVLNKLKEKGLDENT
IVIFTSDNGPHEEGGADPTFFGRDGKLRGLKRQCYEGGIRIPFIVRWPGKVPEGTVNDHQLAFYDLMPTFCDLAGVKNYV
KKYTNKKKDVDYFDGISFAPTLLGQEGQKKHDFLYWEFDETDQIGVRMGDWKMVVKKGTPFLYNLATDIHEDHDIAAGHP
DIVKQMKEIIRTQHTPNPHFSVTLPSFE

Specific function: Plays an important role in the mineralization of sulfates [H]

COG id: COG3119

COG function: function code P; Arylsulfatase A and related enzymes

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sulfatase family [H]

Homologues:

Organism=Homo sapiens, GI71852584, Length=467, Percent_Identity=26.7665952890792, Blast_Score=140, Evalue=3e-33,
Organism=Homo sapiens, GI4503899, Length=414, Percent_Identity=29.2270531400966, Blast_Score=140, Evalue=3e-33,
Organism=Homo sapiens, GI31742482, Length=466, Percent_Identity=26.6094420600858, Blast_Score=137, Evalue=3e-32,
Organism=Homo sapiens, GI146229331, Length=495, Percent_Identity=27.2727272727273, Blast_Score=137, Evalue=3e-32,
Organism=Homo sapiens, GI146229329, Length=495, Percent_Identity=27.2727272727273, Blast_Score=137, Evalue=3e-32,
Organism=Homo sapiens, GI6005990, Length=495, Percent_Identity=27.2727272727273, Blast_Score=137, Evalue=3e-32,
Organism=Homo sapiens, GI146229324, Length=495, Percent_Identity=27.2727272727273, Blast_Score=137, Evalue=3e-32,
Organism=Homo sapiens, GI38569405, Length=535, Percent_Identity=23.1775700934579, Blast_Score=129, Evalue=5e-30,
Organism=Homo sapiens, GI38569407, Length=404, Percent_Identity=25.990099009901, Blast_Score=126, Evalue=4e-29,
Organism=Homo sapiens, GI58743319, Length=474, Percent_Identity=25.9493670886076, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI157266309, Length=447, Percent_Identity=25.0559284116331, Blast_Score=123, Evalue=4e-28,
Organism=Homo sapiens, GI109389362, Length=377, Percent_Identity=25.9946949602122, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI59797060, Length=512, Percent_Identity=22.4609375, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI53831991, Length=161, Percent_Identity=37.888198757764, Blast_Score=106, Evalue=5e-23,
Organism=Homo sapiens, GI71852586, Length=151, Percent_Identity=37.0860927152318, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI45430057, Length=163, Percent_Identity=36.1963190184049, Blast_Score=89, Evalue=9e-18,
Organism=Homo sapiens, GI240255483, Length=432, Percent_Identity=25.462962962963, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI29789100, Length=432, Percent_Identity=25.462962962963, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI240255478, Length=432, Percent_Identity=25.462962962963, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI146229327, Length=395, Percent_Identity=24.5569620253165, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI4557659, Length=436, Percent_Identity=23.8532110091743, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI5360208, Length=338, Percent_Identity=25.7396449704142, Blast_Score=75, Evalue=2e-13,
Organism=Escherichia coli, GI87081924, Length=537, Percent_Identity=26.2569832402235, Blast_Score=136, Evalue=4e-33,
Organism=Escherichia coli, GI1790233, Length=460, Percent_Identity=25.8695652173913, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1790112, Length=396, Percent_Identity=25, Blast_Score=82, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI115533416, Length=477, Percent_Identity=26.4150943396226, Blast_Score=135, Evalue=4e-32,
Organism=Caenorhabditis elegans, GI115533418, Length=468, Percent_Identity=25.8547008547009, Blast_Score=123, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI17559078, Length=151, Percent_Identity=35.7615894039735, Blast_Score=89, Evalue=6e-18,
Organism=Drosophila melanogaster, GI281363223, Length=463, Percent_Identity=24.1900647948164, Blast_Score=140, Evalue=2e-33,
Organism=Drosophila melanogaster, GI24666109, Length=436, Percent_Identity=28.4403669724771, Blast_Score=135, Evalue=6e-32,
Organism=Drosophila melanogaster, GI281366397, Length=400, Percent_Identity=27, Blast_Score=134, Evalue=2e-31,
Organism=Drosophila melanogaster, GI281366395, Length=400, Percent_Identity=27, Blast_Score=134, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24666163, Length=400, Percent_Identity=27, Blast_Score=134, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24666175, Length=447, Percent_Identity=25.9507829977629, Blast_Score=132, Evalue=6e-31,
Organism=Drosophila melanogaster, GI24647401, Length=424, Percent_Identity=26.4150943396226, Blast_Score=95, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017849
- InterPro:   IPR017850
- InterPro:   IPR000917 [H]

Pfam domain/function: PF00884 Sulfatase [H]

EC number: =3.1.6.1 [H]

Molecular weight: Translated: 57749; Mature: 57749

Theoretical pI: Translated: 6.56; Mature: 6.56

Prosite motif: PS00523 SULFATASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNRNLFLLTSGLAFPLLGAYAQKTPKPNIIYIMCDDMGYGDLGCYGQPYISTPNIDNMA
CCCCCEEEEECCCHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHHH
KEGMRFTQAYAGSPVSAPSRASFMTGQHSGHCEVRGNKEYWRDAPVVMYGNNKEYAVVGQ
HHHHHHHHHHCCCCCCCCCCCCEECCCCCCEEEECCCHHHHCCCCEEEECCCCCEEEECC
HPYDPGHVIIPEIMKDNGYTTGMFGKWAGGYEGSVSTPDKRGIDEYYGYICQFQAHLYYP
CCCCCCCEEEHHHHCCCCCEECCCCCCCCCCCCCCCCCCCCCHHHHHCEEEEEEEEEECC
NFLNRYSKSAGDTAVVRVVMDENINYPMFGKDYFKRPQYSADMIHEEAMKWLDKQDGKQP
HHHHHHHCCCCCEEEEEEEECCCCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHCCCCCC
FFGIFTYTLPHAELAQPEDSILTGYQKKFFEDKTWGGQEGSRYNPSVHTHAQFAGMITRL
EEEEEEEECCCHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
DYYVGEVLNKLKEKGLDENTIVIFTSDNGPHEEGGADPTFFGRDGKLRGLKRQCYEGGIR
HHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCEECCCCCCHHHHHHHHHCCCE
IPFIVRWPGKVPEGTVNDHQLAFYDLMPTFCDLAGVKNYVKKYTNKKKDVDYFDGISFAP
EEEEEECCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCCCHHH
TLLGQEGQKKHDFLYWEFDETDQIGVRMGDWKMVVKKGTPFLYNLATDIHEDHDIAAGHP
HHHCCCCCCCCCEEEEEECCCCCCCEEECCEEEEEECCCCEEEEHHHHHCCCCCCCCCCH
DIVKQMKEIIRTQHTPNPHFSVTLPSFE
HHHHHHHHHHHHCCCCCCCEEEECCCCC
>Mature Secondary Structure
MKNRNLFLLTSGLAFPLLGAYAQKTPKPNIIYIMCDDMGYGDLGCYGQPYISTPNIDNMA
CCCCCEEEEECCCHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHHH
KEGMRFTQAYAGSPVSAPSRASFMTGQHSGHCEVRGNKEYWRDAPVVMYGNNKEYAVVGQ
HHHHHHHHHHCCCCCCCCCCCCEECCCCCCEEEECCCHHHHCCCCEEEECCCCCEEEECC
HPYDPGHVIIPEIMKDNGYTTGMFGKWAGGYEGSVSTPDKRGIDEYYGYICQFQAHLYYP
CCCCCCCEEEHHHHCCCCCEECCCCCCCCCCCCCCCCCCCCCHHHHHCEEEEEEEEEECC
NFLNRYSKSAGDTAVVRVVMDENINYPMFGKDYFKRPQYSADMIHEEAMKWLDKQDGKQP
HHHHHHHCCCCCEEEEEEEECCCCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHCCCCCC
FFGIFTYTLPHAELAQPEDSILTGYQKKFFEDKTWGGQEGSRYNPSVHTHAQFAGMITRL
EEEEEEEECCCHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
DYYVGEVLNKLKEKGLDENTIVIFTSDNGPHEEGGADPTFFGRDGKLRGLKRQCYEGGIR
HHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCEECCCCCCHHHHHHHHHCCCE
IPFIVRWPGKVPEGTVNDHQLAFYDLMPTFCDLAGVKNYVKKYTNKKKDVDYFDGISFAP
EEEEEECCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCCCHHH
TLLGQEGQKKHDFLYWEFDETDQIGVRMGDWKMVVKKGTPFLYNLATDIHEDHDIAAGHP
HHHCCCCCCCCCEEEEEECCCCCCCEEECCEEEEEECCCCEEEEHHHHHCCCCCCCCCCH
DIVKQMKEIIRTQHTPNPHFSVTLPSFE
HHHHHHHHHHHHCCCCCCCEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10336424 [H]