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The map label for this gene is pheA [H]

Identifier: 148828305

GI number: 148828305

Start: 1743134

End: 1744291

Strand: Direct

Name: pheA [H]

Synonym: CGSHiGG_09385

Alternate gene names: 148828305

Gene position: 1743134-1744291 (Clockwise)

Preceding gene: 148828304

Following gene: 148828311

Centisome position: 92.37

GC content: 34.37

Gene sequence:

>1158_bases
ATGGCATTAGAATTATCTGACATTCGCCAACAAATTACGCAAATAGATCGTAGTTTATTAAAATTACTTTCTGAGCGTCA
TCGTTTAGCTTTCGATGTAGTGAGAAGTAAAGAGATCTCGCAAAAATCTTTACGTGATGTAGAGCGAGAACAGCAACTTT
TACAAGAACTAGTGCAATTTGCAGAAAATGAAAATTATCAGCTTGAAGCACAATATATCACTTCAATTTTCCAAAAAATC
ATTGAAGACTCGGTATTGACCCAGCAAGTCTATTTGCAGAATAAACTTAATGAACAACGTAATCAAAATTTACATATTGC
TTTTTTAGGTAAGAGAGGGTCTTATTCAAATTTAGCTGCACGTAATTATGCTGCTCGTTATCAAAAACAATTTGTAGAAC
TAGGATGTCAGTCTTTTGAGCAAGTATTTGAAAAAGTTCAGACTGGAGAATCTGACTTTGGTGTGTTACCTTTAGAAAAT
ACAACATCGGGTGCAATTAATGAAGTTTATGATTTACTTCAGCATACTGATTTATCATTAGTGGGAGAGTTGGCATATCC
AATCAAACATTGCGTACTTGTCAATGATAAGACAGATTTGAACCAAATTGATACGTTGTATAGTCATCCTCAAGTGATTC
AACAATGTAGTCAATTTATTCATAGCCTTGATCGCGTGCATATTGAATATTGCGAAAGTAGTTCACACGCAATGCAATTA
GTCGCAAGTTTGAATAAACCTAATATTGCAGCATTGGGCAATGAAGACGGTGGAAAATTGTATGGACTTAGTGTATTAAA
AACTAATATTGCTAATCAAGAGAACAATATTACGCGTTTTATTGTGGTGGCTAAAGAGCCTCGCGAAGTTTCATCACAGA
TTCCCACAAAGACCTTATTATTAATGACAACTTCACAGCAAGCTGGTGCGTTAGTGGATGCTTTATTGGTGTTTAAAAAG
CATCAAATCAATATGACAAAACTGGAATCTCGACCGATTTATGGTAAGCCTTGGGAAGAAATGTTTTATCTAGAAATTGA
AGCAAATATTCATCATCCAGATACAAAACAGGCTTTGGAAGAACTAAAAAATTATAGTAATTACTTAAAGATTTTAGGCT
GTTATCCTAGTGAAATCGTAAAGCCTGTGAGCGTGTAA

Upstream 100 bases:

>100_bases
TTCTGGTGGGAAGTATAGCTTTTTTATTTCATCTCGTGCTTAAATATCGAATGTACTAAAAGTGCGGTCAATTTTGTGGG
ATTTTTTATAAGGAAGCATT

Downstream 100 bases:

>100_bases
AAAAAGTGCGGTCAATAAAAATAATGTTTTTATGACCGCACTTTTTATATTTTTTTGTTCCGTTCTAAAGATTTATGTTG
AATTTTCACCGTTTTTCCTT

Product: cell division protein FtsZ

Products: NA

Alternate protein names: Chorismate mutase; CM; Prephenate dehydratase; PDT [H]

Number of amino acids: Translated: 385; Mature: 384

Protein sequence:

>385_residues
MALELSDIRQQITQIDRSLLKLLSERHRLAFDVVRSKEISQKSLRDVEREQQLLQELVQFAENENYQLEAQYITSIFQKI
IEDSVLTQQVYLQNKLNEQRNQNLHIAFLGKRGSYSNLAARNYAARYQKQFVELGCQSFEQVFEKVQTGESDFGVLPLEN
TTSGAINEVYDLLQHTDLSLVGELAYPIKHCVLVNDKTDLNQIDTLYSHPQVIQQCSQFIHSLDRVHIEYCESSSHAMQL
VASLNKPNIAALGNEDGGKLYGLSVLKTNIANQENNITRFIVVAKEPREVSSQIPTKTLLLMTTSQQAGALVDALLVFKK
HQINMTKLESRPIYGKPWEEMFYLEIEANIHHPDTKQALEELKNYSNYLKILGCYPSEIVKPVSV

Sequences:

>Translated_385_residues
MALELSDIRQQITQIDRSLLKLLSERHRLAFDVVRSKEISQKSLRDVEREQQLLQELVQFAENENYQLEAQYITSIFQKI
IEDSVLTQQVYLQNKLNEQRNQNLHIAFLGKRGSYSNLAARNYAARYQKQFVELGCQSFEQVFEKVQTGESDFGVLPLEN
TTSGAINEVYDLLQHTDLSLVGELAYPIKHCVLVNDKTDLNQIDTLYSHPQVIQQCSQFIHSLDRVHIEYCESSSHAMQL
VASLNKPNIAALGNEDGGKLYGLSVLKTNIANQENNITRFIVVAKEPREVSSQIPTKTLLLMTTSQQAGALVDALLVFKK
HQINMTKLESRPIYGKPWEEMFYLEIEANIHHPDTKQALEELKNYSNYLKILGCYPSEIVKPVSV
>Mature_384_residues
ALELSDIRQQITQIDRSLLKLLSERHRLAFDVVRSKEISQKSLRDVEREQQLLQELVQFAENENYQLEAQYITSIFQKII
EDSVLTQQVYLQNKLNEQRNQNLHIAFLGKRGSYSNLAARNYAARYQKQFVELGCQSFEQVFEKVQTGESDFGVLPLENT
TSGAINEVYDLLQHTDLSLVGELAYPIKHCVLVNDKTDLNQIDTLYSHPQVIQQCSQFIHSLDRVHIEYCESSSHAMQLV
ASLNKPNIAALGNEDGGKLYGLSVLKTNIANQENNITRFIVVAKEPREVSSQIPTKTLLLMTTSQQAGALVDALLVFKKH
QINMTKLESRPIYGKPWEEMFYLEIEANIHHPDTKQALEELKNYSNYLKILGCYPSEIVKPVSV

Specific function: L-phenylalanine biosynthesis. [C]

COG id: COG0077

COG function: function code E; Prephenate dehydratase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate dehydratase domain [H]

Homologues:

Organism=Escherichia coli, GI1788951, Length=376, Percent_Identity=53.9893617021277, Blast_Score=426, Evalue=1e-120,
Organism=Saccharomyces cerevisiae, GI6324013, Length=326, Percent_Identity=25.1533742331288, Blast_Score=96, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008242
- InterPro:   IPR002701
- InterPro:   IPR020822
- InterPro:   IPR010952
- InterPro:   IPR001086
- InterPro:   IPR018528 [H]

Pfam domain/function: PF01817 CM_2; PF00800 PDT [H]

EC number: =5.4.99.5; =4.2.1.51 [H]

Molecular weight: Translated: 44018; Mature: 43886

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: PS00857 PREPHENATE_DEHYDR_1 ; PS00858 PREPHENATE_DEHYDR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALELSDIRQQITQIDRSLLKLLSERHRLAFDVVRSKEISQKSLRDVEREQQLLQELVQF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AENENYQLEAQYITSIFQKIIEDSVLTQQVYLQNKLNEQRNQNLHIAFLGKRGSYSNLAA
HCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHH
RNYAARYQKQFVELGCQSFEQVFEKVQTGESDFGVLPLENTTSGAINEVYDLLQHTDLSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCHHHHHHHHHHHHCCHHH
VGELAYPIKHCVLVNDKTDLNQIDTLYSHPQVIQQCSQFIHSLDRVHIEYCESSSHAMQL
HHHHHHHHHHEEEECCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
VASLNKPNIAALGNEDGGKLYGLSVLKTNIANQENNITRFIVVAKEPREVSSQIPTKTLL
HHHCCCCCEEEECCCCCCEEEEHHHHHHHHCCCCCCCEEEEEEECCCHHHHHHCCCEEEE
LMTTSQQAGALVDALLVFKKHQINMTKLESRPIYGKPWEEMFYLEIEANIHHPDTKQALE
EEECCCHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCHHHEEEEEEECCCCCCCHHHHHH
ELKNYSNYLKILGCYPSEIVKPVSV
HHHHHHHHHHHHCCCHHHHCCCCCC
>Mature Secondary Structure 
ALELSDIRQQITQIDRSLLKLLSERHRLAFDVVRSKEISQKSLRDVEREQQLLQELVQF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AENENYQLEAQYITSIFQKIIEDSVLTQQVYLQNKLNEQRNQNLHIAFLGKRGSYSNLAA
HCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHH
RNYAARYQKQFVELGCQSFEQVFEKVQTGESDFGVLPLENTTSGAINEVYDLLQHTDLSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCHHHHHHHHHHHHCCHHH
VGELAYPIKHCVLVNDKTDLNQIDTLYSHPQVIQQCSQFIHSLDRVHIEYCESSSHAMQL
HHHHHHHHHHEEEECCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
VASLNKPNIAALGNEDGGKLYGLSVLKTNIANQENNITRFIVVAKEPREVSSQIPTKTLL
HHHCCCCCEEEECCCCCCEEEEHHHHHHHHCCCCCCCEEEEEEECCCHHHHHHCCCEEEE
LMTTSQQAGALVDALLVFKKHQINMTKLESRPIYGKPWEEMFYLEIEANIHHPDTKQALE
EEECCCHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCHHHEEEEEEECCCCCCCHHHHHH
ELKNYSNYLKILGCYPSEIVKPVSV
HHHHHHHHHHHHCCCHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]