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The map label for this gene is nrfX [H]

Identifier: 148828112

GI number: 148828112

Start: 1524738

End: 1525265

Strand: Reverse

Name: nrfX [H]

Synonym: CGSHiGG_08240

Alternate gene names: 148828112

Gene position: 1525265-1524738 (Counterclockwise)

Preceding gene: 148828113

Following gene: 148828111

Centisome position: 80.82

GC content: 39.02

Gene sequence:

>528_bases
ATGAAAAAACTTATCTTTTTTACACCGCTCTTTGTGCTTTTAGGCGTGTGTATATTATTAATTGCAGGGTTAAATCAAGA
TCCGAAAAAAATTGCTTCGGCTTTAATTGATAAACCTGTTCCAGAGTTTTATCAGGCTAATTTACATGAGCCATCACAAA
TCGTAAGCCCGAAAGAGTTTCCTAAACAGCCATTTTTATTAAATGTGTGGGGAAGTTGGTGTGGTTATTGCAAGGAAGAG
CATCCGCTGTTGATTGAGATTGCAAAAACGTTGCCTATTGTGGGCGTGGATTACCGTGATAATCCGCAAAATGGCATTGA
AATGCTTAAGCGAATGGGCAATCCGTTCGTCTTGACCATTGATGATAGTCATGGTGAATTGGGATTAAAATTGGGCGTGG
ATGGCGCACCAGAAACTTATCTTGTAGATGAAAATGGTGTGATTCGTTATCGCCATTCTGGTTTACTGGATAAAGCAACT
TGGCAAACGGTATTTTTGCCGAAAATTGAAGCATTGAAGAACAAATGA

Upstream 100 bases:

>100_bases
ATTATAAACCACTGATTCGTTGGCTTTGGGCGGGCGGTATTTTAATGGCCTTTGGCGCACTTTTTAGCGTCTTCGGATTA
CGCAGAAAACAGGAAAAATA

Downstream 100 bases:

>100_bases
AAAGTATATTAGATATTTTTACTCGCGGTTTTATTCAGGTTCAAAAAACAGTCTTTTTTGCAACCGCACTTTTATTCGCA
TTTTCCTTATTCGCCCGAGC

Product: hypothetical protein

Products: NA

Alternate protein names: Cytochrome c biogenesis protein NrfX [H]

Number of amino acids: Translated: 175; Mature: 175

Protein sequence:

>175_residues
MKKLIFFTPLFVLLGVCILLIAGLNQDPKKIASALIDKPVPEFYQANLHEPSQIVSPKEFPKQPFLLNVWGSWCGYCKEE
HPLLIEIAKTLPIVGVDYRDNPQNGIEMLKRMGNPFVLTIDDSHGELGLKLGVDGAPETYLVDENGVIRYRHSGLLDKAT
WQTVFLPKIEALKNK

Sequences:

>Translated_175_residues
MKKLIFFTPLFVLLGVCILLIAGLNQDPKKIASALIDKPVPEFYQANLHEPSQIVSPKEFPKQPFLLNVWGSWCGYCKEE
HPLLIEIAKTLPIVGVDYRDNPQNGIEMLKRMGNPFVLTIDDSHGELGLKLGVDGAPETYLVDENGVIRYRHSGLLDKAT
WQTVFLPKIEALKNK
>Mature_175_residues
MKKLIFFTPLFVLLGVCILLIAGLNQDPKKIASALIDKPVPEFYQANLHEPSQIVSPKEFPKQPFLLNVWGSWCGYCKEE
HPLLIEIAKTLPIVGVDYRDNPQNGIEMLKRMGNPFVLTIDDSHGELGLKLGVDGAPETYLVDENGVIRYRHSGLLDKAT
WQTVFLPKIEALKNK

Specific function: Could be involved in disulfide bond formation. Could catalyzes a late, reductive step in the assembly of periplasmic NrfA c-type cytochrome, probably the reduction of disulfide bonds of the apocytochrome c to allow covalent linkage with the heme. Possible

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein; Periplasmic side (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1788523, Length=177, Percent_Identity=41.2429378531073, Blast_Score=142, Evalue=1e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004799
- InterPro:   IPR013740
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR012335 [H]

Pfam domain/function: PF08534 Redoxin [H]

EC number: NA

Molecular weight: Translated: 19682; Mature: 19682

Theoretical pI: Translated: 6.94; Mature: 6.94

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLIFFTPLFVLLGVCILLIAGLNQDPKKIASALIDKPVPEFYQANLHEPSQIVSPKEF
CCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHCCCCCCHHHCCCHHC
PKQPFLLNVWGSWCGYCKEEHPLLIEIAKTLPIVGVDYRDNPQNGIEMLKRMGNPFVLTI
CCCCEEEEECHHHHCCCCCCCCEEEEEHHHCCEEECCCCCCCHHHHHHHHHCCCCEEEEE
DDSHGELGLKLGVDGAPETYLVDENGVIRYRHSGLLDKATWQTVFLPKIEALKNK
ECCCCCEEEEECCCCCCCEEEECCCCEEEEECCCCCCCCCCCEEECCHHHHHCCC
>Mature Secondary Structure
MKKLIFFTPLFVLLGVCILLIAGLNQDPKKIASALIDKPVPEFYQANLHEPSQIVSPKEF
CCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHCCCCCCHHHCCCHHC
PKQPFLLNVWGSWCGYCKEEHPLLIEIAKTLPIVGVDYRDNPQNGIEMLKRMGNPFVLTI
CCCCEEEEECHHHHCCCCCCCCEEEEEHHHCCEEECCCCCCCHHHHHHHHHCCCCEEEEE
DDSHGELGLKLGVDGAPETYLVDENGVIRYRHSGLLDKATWQTVFLPKIEALKNK
ECCCCCEEEEECCCCCCCEEEECCCCEEEEECCCCCCCCCCCEEECCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]