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The map label for this gene is siaT [H]

Identifier: 148827288

GI number: 148827288

Start: 619384

End: 621234

Strand: Direct

Name: siaT [H]

Synonym: CGSHiGG_03325

Alternate gene names: 148827288

Gene position: 619384-621234 (Clockwise)

Preceding gene: 148827287

Following gene: 148827289

Centisome position: 32.82

GC content: 37.55

Gene sequence:

>1851_bases
ATGAAATATATTAATAAGCTTGAGGAATGGCTGGGTGGCGCATTATTTATCGCCATTTTCGGTATTCTTATCGCTCAAAT
TCTTTCACGCCAAGTTTTTCATTCTCCGTTAATTTGGAGTGAAGAACTCGCCAAGCTCTTATTTGTTTACGTGGGTATGT
TGGGTATCAGCGTTGCTGTGAGAAAACAAGAACACGTATTTATTGATTTTTTAACTAATCTAATGCCCGAAAAAATCAGA
AAATTCACAAATACGTTTGTACAATTATTAGTCTTTATATGTATTTTCTTATTTATTCATTTCGGTATTCGTACTTTTAA
CGGTGCATCATTCCCTATTGATGCCTTAGGAGGCATTTCTGAAAAATGGATTTTCGCAGCACTGCCTGTTATCGCAATAT
TAATGATGTTTCGCTTTATCCAAGCGCAAACCCTAAACTTTAAGACAGGGAAAAGCTATTTACCTGCAACTTTCTTTATC
ATAAGTGCGGTCATTTTATTTGCGATTTTATTTTTCGCGCCAGATTGGTTCAAAGTATTGCGTATTAGCAATTATATAAA
ACTCGGTTCAAGTTCAGTCTATGTCGCCTTACTCGTTTGGCTAATCATTATGTTTATCGGTGTCCCTGTAGGTTGGTCCT
TATTTATTGCTACTCTACTTTATTTTTCTATGACACGTTGGAACGTCGTAAATGCCGCAACTGAAAAATTAGTCTATAGC
CTAGACAGCTTCCCATTACTTGCCGTGCCATTTTATATTTTAACGGGCATTCTAATGAATACAGGTGGGATTACCGAACG
TATTTTTAATTTCGCTAAAGCCTTACTCGGTCATTACACAGGAGGAATGGGACACGTTAATATCGGCGCAAGTTTATTGT
TCTCTGGTATGTCAGGTTCAGCACTTGCTGATGCGGGGGGCTTAGGTCAATTGGAAATCAAAGCAATGCGTGATGCTGGT
TATGACGATGATATTTGCGGAGGAATTACTGCTGCTTCTTGTATTATTGGGCCATTAGTTCCGCCAAGTATTGCAATGAT
TATTTACGGTGTAATTGCCAATGAATCTATCGCAAAACTCTTTATTGCAGGTTTTATTCCAGGTGTATTAATTACTTTAG
CTTTAATGGCAATGAATTATCGGATTGCAAAAAAACGAGGTTATCCACGTACACCAAAAGCTACGAGAGAACAACTTTGC
AGCAGCTTTAAACAATCTTTTTGGGCAATCTTAACGCCGTTATTAATTATCGGTGGTATTTTTTCAGGCTTATTCAGTCC
AACAGAATCTGCCATTGTTGCAGCAGCATACTCTGTAATTATTGGTAAATTCGTGTATAAAGAATTAACCTTAAAAAGCT
TATTTAATAGTTGCATAGAAGCAATGGCAATTACGGGCGTAGTCGCCTTAATGATTATGACTGTGACTTTCTTTGGCGAT
ATGATTGCGCGTGAACAAGTCGCAATGCGTGTTGCTGATGTGTTTGTTGCCGTTGCCGATTCGCCTTTAACCGTATTGAT
AATGATTAACGCACTGCTACTTTTTCTTGGAATGTTCATTGATGCCCTAGCATTACAATTTTTAGTATTACCAATGCTTA
TTCCTATCGCAATGCAGTTCAATATTGACTTAATCTTCTTTGGTGTAATGACCACATTAAATATGATGGTTGGTATTCTT
ACCCCACCAATGGGAATGGCTCTCTTTGTTGTTGCTCGTGTAGGAAATATGTCAGTTTCCACGGTAACCAAAGGCGTATT
ACCGTTCTTGATTCCCGTTTTCGTCACATTAGTATTAATCACGATTTTCCCACAAATCATCACATTTGTGCCAAATCTAT
TGATACCATAA

Upstream 100 bases:

>100_bases
TCAGCTTTAAAACAAATTGAAGCAATCAATCCATAATCCCTCTTTAGTGTGCCGTAATGGCACACTACATTCCCTTATTC
TTCATCAAACGGAGTGAAGT

Downstream 100 bases:

>100_bases
TAAAAAGTGCGGTTGAAAAACATTAAATTTTTTAACCGCACTTTCATCGTTTTCGTAAGTTACATCTGCTGTATCTTACA
ATACAAAAGGGTGCAATAAC

Product: hypothetical protein

Products: NA

Alternate protein names: N-acetylneuraminic acid permease; N-acetylneuraminic acid transporter; Neu5Ac permease [H]

Number of amino acids: Translated: 616; Mature: 616

Protein sequence:

>616_residues
MKYINKLEEWLGGALFIAIFGILIAQILSRQVFHSPLIWSEELAKLLFVYVGMLGISVAVRKQEHVFIDFLTNLMPEKIR
KFTNTFVQLLVFICIFLFIHFGIRTFNGASFPIDALGGISEKWIFAALPVIAILMMFRFIQAQTLNFKTGKSYLPATFFI
ISAVILFAILFFAPDWFKVLRISNYIKLGSSSVYVALLVWLIIMFIGVPVGWSLFIATLLYFSMTRWNVVNAATEKLVYS
LDSFPLLAVPFYILTGILMNTGGITERIFNFAKALLGHYTGGMGHVNIGASLLFSGMSGSALADAGGLGQLEIKAMRDAG
YDDDICGGITAASCIIGPLVPPSIAMIIYGVIANESIAKLFIAGFIPGVLITLALMAMNYRIAKKRGYPRTPKATREQLC
SSFKQSFWAILTPLLIIGGIFSGLFSPTESAIVAAAYSVIIGKFVYKELTLKSLFNSCIEAMAITGVVALMIMTVTFFGD
MIAREQVAMRVADVFVAVADSPLTVLIMINALLLFLGMFIDALALQFLVLPMLIPIAMQFNIDLIFFGVMTTLNMMVGIL
TPPMGMALFVVARVGNMSVSTVTKGVLPFLIPVFVTLVLITIFPQIITFVPNLLIP

Sequences:

>Translated_616_residues
MKYINKLEEWLGGALFIAIFGILIAQILSRQVFHSPLIWSEELAKLLFVYVGMLGISVAVRKQEHVFIDFLTNLMPEKIR
KFTNTFVQLLVFICIFLFIHFGIRTFNGASFPIDALGGISEKWIFAALPVIAILMMFRFIQAQTLNFKTGKSYLPATFFI
ISAVILFAILFFAPDWFKVLRISNYIKLGSSSVYVALLVWLIIMFIGVPVGWSLFIATLLYFSMTRWNVVNAATEKLVYS
LDSFPLLAVPFYILTGILMNTGGITERIFNFAKALLGHYTGGMGHVNIGASLLFSGMSGSALADAGGLGQLEIKAMRDAG
YDDDICGGITAASCIIGPLVPPSIAMIIYGVIANESIAKLFIAGFIPGVLITLALMAMNYRIAKKRGYPRTPKATREQLC
SSFKQSFWAILTPLLIIGGIFSGLFSPTESAIVAAAYSVIIGKFVYKELTLKSLFNSCIEAMAITGVVALMIMTVTFFGD
MIAREQVAMRVADVFVAVADSPLTVLIMINALLLFLGMFIDALALQFLVLPMLIPIAMQFNIDLIFFGVMTTLNMMVGIL
TPPMGMALFVVARVGNMSVSTVTKGVLPFLIPVFVTLVLITIFPQIITFVPNLLIP
>Mature_616_residues
MKYINKLEEWLGGALFIAIFGILIAQILSRQVFHSPLIWSEELAKLLFVYVGMLGISVAVRKQEHVFIDFLTNLMPEKIR
KFTNTFVQLLVFICIFLFIHFGIRTFNGASFPIDALGGISEKWIFAALPVIAILMMFRFIQAQTLNFKTGKSYLPATFFI
ISAVILFAILFFAPDWFKVLRISNYIKLGSSSVYVALLVWLIIMFIGVPVGWSLFIATLLYFSMTRWNVVNAATEKLVYS
LDSFPLLAVPFYILTGILMNTGGITERIFNFAKALLGHYTGGMGHVNIGASLLFSGMSGSALADAGGLGQLEIKAMRDAG
YDDDICGGITAASCIIGPLVPPSIAMIIYGVIANESIAKLFIAGFIPGVLITLALMAMNYRIAKKRGYPRTPKATREQLC
SSFKQSFWAILTPLLIIGGIFSGLFSPTESAIVAAAYSVIIGKFVYKELTLKSLFNSCIEAMAITGVVALMIMTVTFFGD
MIAREQVAMRVADVFVAVADSPLTVLIMINALLLFLGMFIDALALQFLVLPMLIPIAMQFNIDLIFFGVMTTLNMMVGIL
TPPMGMALFVVARVGNMSVSTVTKGVLPFLIPVFVTLVLITIFPQIITFVPNLLIP

Specific function: Part of the tripartite ATP-independent periplasmic (TRAP) transport system siaPT involved in the uptake of sialic acid [H]

COG id: COG1593

COG function: function code G; TRAP-type C4-dicarboxylate transport system, large permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the TRAP transporter large permease family [H]

Homologues:

Organism=Escherichia coli, GI48994950, Length=384, Percent_Identity=36.1979166666667, Blast_Score=222, Evalue=6e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010656
- InterPro:   IPR007387
- InterPro:   IPR004681 [H]

Pfam domain/function: PF06808 DctM; PF04290 DctQ [H]

EC number: NA

Molecular weight: Translated: 67608; Mature: 67608

Theoretical pI: Translated: 9.44; Mature: 9.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHCCC
>Mature Secondary Structure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HHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]