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The map label for this gene is nanM [H]

Identifier: 148827289

GI number: 148827289

Start: 621410

End: 622537

Strand: Direct

Name: nanM [H]

Synonym: CGSHiGG_03330

Alternate gene names: 148827289

Gene position: 621410-622537 (Clockwise)

Preceding gene: 148827288

Following gene: 148827290

Centisome position: 32.93

GC content: 40.25

Gene sequence:

>1128_bases
ATGAAACTAACTAAAACAGCATTATGCACTGCACTTTTTGCCACCTTTACTTTTTCAGCGAACGCACAAACTTATCCTGA
TTTGCCAGTGGGGATCAAAGGAGGAACAGGCGCATTAATTGGCGACACAGTTTATGTGGGATTAGGTTCTGGTGGCGATA
AATTCTATACCTTAGACCTAAAAGATCCTTCAGCACAATGGAAAGAAATTGCTACATTTCCGGGTGGCGAACGCAATCAA
CCTGTTGCAGCCGCAGTGGATGGAAAACTTTATGTATTCGGTGGTTTACAAAAAAATGAAAAAGGCGAACTTCAACTCGT
TAATGACGCTTATCGCTATAATCCAAGCGATAATACTTGGATGAAACTTCCTACTCGTTCTCCCCGTGGTTTAGTAGGAT
CAAGTGGTGCATCTCACGGAGATAAAGTTTATATTTTAGGCGGTTCTAATCTCTCTATATTTAATGGTTTCTTCCAAGAC
ACTGTGGCAGCAGGTGAAGATAAAGCGAAAAAAGATGAAATCGCAGCAGCTTACTTCGATCAACGTCCAGAAGATTATTT
CTTTACAACAGAATTATTGAGCTATGAACCCTCAACCAACAAATGGCGCAATGAAGGTCGTATTCCATTCTCTGGTCGTG
CTGGTGCAGCCTTTACAATTCAAGGTAATGATCTCGTGGTTGTCAATGGCGAAATTAAACCTGGACTTCGCACCGCTGAA
ACCCATCAAGGTAAATTCACTGCTAAAGGTGTGCAATGGAAAAACTTACCTGACTTACCTGCTCCAAAAGGCAAATCACA
AGATGGTTTAGCTGGTGCGCTTTCAGGCTATAGTAACGGTCATTATTTAGTCACTGGTGGAGCAAATTTTCCAGGTTCAA
TCAAACAATTCAAAGAAGGAAAACTTCACGCACATAAAGGTTTAAGCAAAGCTTGGCATAACGAAGTTTATACGTTGAAT
AATGGTAAATGGCGCATTGTTGGGGAATTACCAATGAATATTGGTTATGGTTTTTCTGTATCTTACAACAATAAAGTTTT
ACTGATTGGCGGTGAAACTGATGGAGGTAAGGCTTTAACTAGCGTCAAAGCAATAAGCTATGACGGTAAAAAATTGACCA
TCGAATAA

Upstream 100 bases:

>100_bases
TTACAATACAAAAGGGTGCAATAACTGCACTTTATCAACGCCTATTCAATGCCGTTTAATGAATAGAAAACTGTAAACAC
AACTCAAAATGGGGTTTATT

Downstream 100 bases:

>100_bases
TTTATCACAGAATAGTGCATAAAATTTATAATAATCAAAAGCGGCGAAATTTATCGCCGCTTTATGCAAAATAAAAGTAA
TTAAAGCAAAATTAACACAA

Product: N-acetylneuraminic acid mutarotase

Products: NA

Alternate protein names: N-acetylneuraminate mutarotase; Neu5Ac mutarotase; Sialic acid epimerase [H]

Number of amino acids: Translated: 375; Mature: 375

Protein sequence:

>375_residues
MKLTKTALCTALFATFTFSANAQTYPDLPVGIKGGTGALIGDTVYVGLGSGGDKFYTLDLKDPSAQWKEIATFPGGERNQ
PVAAAVDGKLYVFGGLQKNEKGELQLVNDAYRYNPSDNTWMKLPTRSPRGLVGSSGASHGDKVYILGGSNLSIFNGFFQD
TVAAGEDKAKKDEIAAAYFDQRPEDYFFTTELLSYEPSTNKWRNEGRIPFSGRAGAAFTIQGNDLVVVNGEIKPGLRTAE
THQGKFTAKGVQWKNLPDLPAPKGKSQDGLAGALSGYSNGHYLVTGGANFPGSIKQFKEGKLHAHKGLSKAWHNEVYTLN
NGKWRIVGELPMNIGYGFSVSYNNKVLLIGGETDGGKALTSVKAISYDGKKLTIE

Sequences:

>Translated_375_residues
MKLTKTALCTALFATFTFSANAQTYPDLPVGIKGGTGALIGDTVYVGLGSGGDKFYTLDLKDPSAQWKEIATFPGGERNQ
PVAAAVDGKLYVFGGLQKNEKGELQLVNDAYRYNPSDNTWMKLPTRSPRGLVGSSGASHGDKVYILGGSNLSIFNGFFQD
TVAAGEDKAKKDEIAAAYFDQRPEDYFFTTELLSYEPSTNKWRNEGRIPFSGRAGAAFTIQGNDLVVVNGEIKPGLRTAE
THQGKFTAKGVQWKNLPDLPAPKGKSQDGLAGALSGYSNGHYLVTGGANFPGSIKQFKEGKLHAHKGLSKAWHNEVYTLN
NGKWRIVGELPMNIGYGFSVSYNNKVLLIGGETDGGKALTSVKAISYDGKKLTIE
>Mature_375_residues
MKLTKTALCTALFATFTFSANAQTYPDLPVGIKGGTGALIGDTVYVGLGSGGDKFYTLDLKDPSAQWKEIATFPGGERNQ
PVAAAVDGKLYVFGGLQKNEKGELQLVNDAYRYNPSDNTWMKLPTRSPRGLVGSSGASHGDKVYILGGSNLSIFNGFFQD
TVAAGEDKAKKDEIAAAYFDQRPEDYFFTTELLSYEPSTNKWRNEGRIPFSGRAGAAFTIQGNDLVVVNGEIKPGLRTAE
THQGKFTAKGVQWKNLPDLPAPKGKSQDGLAGALSGYSNGHYLVTGGANFPGSIKQFKEGKLHAHKGLSKAWHNEVYTLN
NGKWRIVGELPMNIGYGFSVSYNNKVLLIGGETDGGKALTSVKAISYDGKKLTIE

Specific function: Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, whic

COG id: COG3055

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 7 Kelch repeats [H]

Homologues:

Organism=Escherichia coli, GI87082419, Length=375, Percent_Identity=43.4666666666667, Blast_Score=319, Evalue=2e-88,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013089
- InterPro:   IPR015915
- InterPro:   IPR006652
- InterPro:   IPR019936 [H]

Pfam domain/function: PF01344 Kelch_1 [H]

EC number: NA

Molecular weight: Translated: 40330; Mature: 40330

Theoretical pI: Translated: 9.44; Mature: 9.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLTKTALCTALFATFTFSANAQTYPDLPVGIKGGTGALIGDTVYVGLGSGGDKFYTLDL
CCCHHHHHHHHHHHHEEECCCCCCCCCCCEEECCCCCEEEECEEEEEECCCCCEEEEEEE
KDPSAQWKEIATFPGGERNQPVAAAVDGKLYVFGGLQKNEKGELQLVNDAYRYNPSDNTW
CCCCCHHHHHCCCCCCCCCCCEEEEECCEEEEEECCCCCCCCCEEEEEEEEEECCCCCCE
MKLPTRSPRGLVGSSGASHGDKVYILGGSNLSIFNGFFQDTVAAGEDKAKKDEIAAAYFD
EEECCCCCCCCCCCCCCCCCCEEEEEECCCEEEEHHHHHHHHHCCCCCCCHHHHHEHHHC
QRPEDYFFTTELLSYEPSTNKWRNEGRIPFSGRAGAAFTIQGNDLVVVNGEIKPGLRTAE
CCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCCCCEEEEEECCEEEEECCCCCCCCCCCC
THQGKFTAKGVQWKNLPDLPAPKGKSQDGLAGALSGYSNGHYLVTGGANFPGSIKQFKEG
CCCCEEEECCEEECCCCCCCCCCCCCCCCCEEHHCCCCCCCEEEECCCCCCHHHHHHHCC
KLHAHKGLSKAWHNEVYTLNNGKWRIVGELPMNIGYGFSVSYNNKVLLIGGETDGGKALT
CCHHHHCHHHHHCCCEEEEECCCEEEEEECCCCCCCEEEEECCCEEEEEECCCCCCCEEE
SVKAISYDGKKLTIE
EEEEEEECCCEEEEC
>Mature Secondary Structure
MKLTKTALCTALFATFTFSANAQTYPDLPVGIKGGTGALIGDTVYVGLGSGGDKFYTLDL
CCCHHHHHHHHHHHHEEECCCCCCCCCCCEEECCCCCEEEECEEEEEECCCCCEEEEEEE
KDPSAQWKEIATFPGGERNQPVAAAVDGKLYVFGGLQKNEKGELQLVNDAYRYNPSDNTW
CCCCCHHHHHCCCCCCCCCCCEEEEECCEEEEEECCCCCCCCCEEEEEEEEEECCCCCCE
MKLPTRSPRGLVGSSGASHGDKVYILGGSNLSIFNGFFQDTVAAGEDKAKKDEIAAAYFD
EEECCCCCCCCCCCCCCCCCCEEEEEECCCEEEEHHHHHHHHHCCCCCCCHHHHHEHHHC
QRPEDYFFTTELLSYEPSTNKWRNEGRIPFSGRAGAAFTIQGNDLVVVNGEIKPGLRTAE
CCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCCCCEEEEEECCEEEEECCCCCCCCCCCC
THQGKFTAKGVQWKNLPDLPAPKGKSQDGLAGALSGYSNGHYLVTGGANFPGSIKQFKEG
CCCCEEEECCEEECCCCCCCCCCCCCCCCCEEHHCCCCCCCEEEECCCCCCHHHHHHHCC
KLHAHKGLSKAWHNEVYTLNNGKWRIVGELPMNIGYGFSVSYNNKVLLIGGETDGGKALT
CCHHHHCHHHHHCCCEEEEECCCEEEEEECCCCCCCEEEEECCCEEEEEECCCCCCCEEE
SVKAISYDGKKLTIE
EEEEEEECCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA