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The map label for this gene is siaP [H]

Identifier: 148827287

GI number: 148827287

Start: 618333

End: 619319

Strand: Direct

Name: siaP [H]

Synonym: CGSHiGG_03320

Alternate gene names: 148827287

Gene position: 618333-619319 (Clockwise)

Preceding gene: 148827280

Following gene: 148827288

Centisome position: 32.76

GC content: 36.88

Gene sequence:

>987_bases
ATGAAATTGACAAAACTTTTCCTTGCCACCGCCATTTCTTTAGGCGTATCTTCTGCTGTTCTTGCCGCTGATTATGACTT
GAAATTCGGTATGAATGCTGGAACTTCATCAAATGAATATAAAGCGGCAGAAATGTTTGCCAAAGAAGTCAAAGAAAAAT
CACAGGGTAAAATTGAAATTTCACTTTATCCAAGTTCACAATTAGGTGATGACCGTGCAATGTTAAAACAATTAAAAGAC
GGTTCTCTCGACTTTACCTTTGCAGAATCTGCTCGCTTCCAGCTGTTTTACCCTGAAGCGGCAGTATTTGCCTTACCTTA
TGTTATTAGCAACTACAATGTTGCACAAAAAGCCTTATTCGATACAGAATTCGGTAAAGATTTAATTAAAAAAATGGACA
AAGATCTTGGCGTGACTTTACTTTCCCAAGCTTATAACGGAACTCGCCAAACGACTTCAAATCGTGCAATCAACAGTATT
GCAGATATGAAAGGCTTAAAACTTCGTGTGCCAAATGCAGCAACAAACTTAGCCTATGCTAAATATGTTGGCGCATCACC
AACACCAATGGCATTTTCTGAAGTTTATCTTGCGTTACAAACCAATGCCGTCGATGGTCAAGAAAACCCGTTAGCAGCGG
TGCAAGCACAAAAATTCTATGAAGTGCAAAAGTTCTTAGCAATGACTAATCACATTTTGAATGACCAACTTTATTTAGTA
AGCAACGAGACTTATAAAGAACTCCCTGAAGATCTTCAAAAAGTCGTAAAAGATGCTGCCGAAAATGCAGCAAAATATCA
CACTAAATTATTCGTAGATGGAGAGAAAGATTTAGTCACATTCTTTGAAAAACAAGGCGTGAAAATTACACATCCTGATC
TTGTTCCATTTAAAGAATCAATGAAGCCGTATTATGCTGAGTTTGTAAAACAAACTGGTCAAAAAGGTGAATCAGCTTTA
AAACAAATTGAAGCAATCAATCCATAA

Upstream 100 bases:

>100_bases
ATTTTTGGGGAGAAAACATACATTTTTTGCCTAAATTGATTCTCATATTATGGGGTTAATATTCCCCTTTCCAACATAAG
TTCACACAGGAGCGAATATG

Downstream 100 bases:

>100_bases
TCCCTCTTTAGTGTGCCGTAATGGCACACTACATTCCCTTATTCTTCATCAAACGGAGTGAAGTATGAAATATATTAATA
AGCTTGAGGAATGGCTGGGT

Product: hypothetical protein

Products: NA

Alternate protein names: Extracytoplasmic solute receptor protein siaP; N-acetylneuraminic-binding protein; Neu5Ac-binding protein [H]

Number of amino acids: Translated: 328; Mature: 328

Protein sequence:

>328_residues
MKLTKLFLATAISLGVSSAVLAADYDLKFGMNAGTSSNEYKAAEMFAKEVKEKSQGKIEISLYPSSQLGDDRAMLKQLKD
GSLDFTFAESARFQLFYPEAAVFALPYVISNYNVAQKALFDTEFGKDLIKKMDKDLGVTLLSQAYNGTRQTTSNRAINSI
ADMKGLKLRVPNAATNLAYAKYVGASPTPMAFSEVYLALQTNAVDGQENPLAAVQAQKFYEVQKFLAMTNHILNDQLYLV
SNETYKELPEDLQKVVKDAAENAAKYHTKLFVDGEKDLVTFFEKQGVKITHPDLVPFKESMKPYYAEFVKQTGQKGESAL
KQIEAINP

Sequences:

>Translated_328_residues
MKLTKLFLATAISLGVSSAVLAADYDLKFGMNAGTSSNEYKAAEMFAKEVKEKSQGKIEISLYPSSQLGDDRAMLKQLKD
GSLDFTFAESARFQLFYPEAAVFALPYVISNYNVAQKALFDTEFGKDLIKKMDKDLGVTLLSQAYNGTRQTTSNRAINSI
ADMKGLKLRVPNAATNLAYAKYVGASPTPMAFSEVYLALQTNAVDGQENPLAAVQAQKFYEVQKFLAMTNHILNDQLYLV
SNETYKELPEDLQKVVKDAAENAAKYHTKLFVDGEKDLVTFFEKQGVKITHPDLVPFKESMKPYYAEFVKQTGQKGESAL
KQIEAINP
>Mature_328_residues
MKLTKLFLATAISLGVSSAVLAADYDLKFGMNAGTSSNEYKAAEMFAKEVKEKSQGKIEISLYPSSQLGDDRAMLKQLKD
GSLDFTFAESARFQLFYPEAAVFALPYVISNYNVAQKALFDTEFGKDLIKKMDKDLGVTLLSQAYNGTRQTTSNRAINSI
ADMKGLKLRVPNAATNLAYAKYVGASPTPMAFSEVYLALQTNAVDGQENPLAAVQAQKFYEVQKFLAMTNHILNDQLYLV
SNETYKELPEDLQKVVKDAAENAAKYHTKLFVDGEKDLVTFFEKQGVKITHPDLVPFKESMKPYYAEFVKQTGQKGESAL
KQIEAINP

Specific function: Part of the tripartite ATP-independent periplasmic (TRAP) transport system siaPT involved in the uptake of sialic acid. This protein specifically binds sialic acid [H]

COG id: COG1638

COG function: function code G; TRAP-type C4-dicarboxylate transport system, periplasmic component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 7 family [H]

Homologues:

Organism=Escherichia coli, GI1790004, Length=324, Percent_Identity=31.4814814814815, Blast_Score=164, Evalue=6e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018389
- InterPro:   IPR004682 [H]

Pfam domain/function: PF03480 SBP_bac_7 [H]

EC number: NA

Molecular weight: Translated: 36382; Mature: 36382

Theoretical pI: Translated: 6.82; Mature: 6.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLTKLFLATAISLGVSSAVLAADYDLKFGMNAGTSSNEYKAAEMFAKEVKEKSQGKIEI
CCHHHHHHHHHHHHCHHHHHEEECCCEEECCCCCCCCCCHHHHHHHHHHHHHHCCCEEEE
SLYPSSQLGDDRAMLKQLKDGSLDFTFAESARFQLFYPEAAVFALPYVISNYNVAQKALF
EECCCCCCCCHHHHHHHHCCCCCEEEEECCCEEEEECCCHHHHHHHHHHCCCCHHHHHHH
DTEFGKDLIKKMDKDLGVTLLSQAYNGTRQTTSNRAINSIADMKGLKLRVPNAATNLAYA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCHHHHHHHHHHHCCCCEEECCCCHHHHHHH
KYVGASPTPMAFSEVYLALQTNAVDGQENPLAAVQAQKFYEVQKFLAMTNHILNDQLYLV
HHCCCCCCCHHHHHEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEE
SNETYKELPEDLQKVVKDAAENAAKYHTKLFVDGEKDLVTFFEKQGVKITHPDLVPFKES
ECCHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHCCCEEECCCCCCCHHH
MKPYYAEFVKQTGQKGESALKQIEAINP
CCHHHHHHHHHHCCHHHHHHHHHHCCCC
>Mature Secondary Structure
MKLTKLFLATAISLGVSSAVLAADYDLKFGMNAGTSSNEYKAAEMFAKEVKEKSQGKIEI
CCHHHHHHHHHHHHCHHHHHEEECCCEEECCCCCCCCCCHHHHHHHHHHHHHHCCCEEEE
SLYPSSQLGDDRAMLKQLKDGSLDFTFAESARFQLFYPEAAVFALPYVISNYNVAQKALF
EECCCCCCCCHHHHHHHHCCCCCEEEEECCCEEEEECCCHHHHHHHHHHCCCCHHHHHHH
DTEFGKDLIKKMDKDLGVTLLSQAYNGTRQTTSNRAINSIADMKGLKLRVPNAATNLAYA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCHHHHHHHHHHHCCCCEEECCCCHHHHHHH
KYVGASPTPMAFSEVYLALQTNAVDGQENPLAAVQAQKFYEVQKFLAMTNHILNDQLYLV
HHCCCCCCCHHHHHEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEE
SNETYKELPEDLQKVVKDAAENAAKYHTKLFVDGEKDLVTFFEKQGVKITHPDLVPFKES
ECCHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHCCCEEECCCCCCCHHH
MKPYYAEFVKQTGQKGESALKQIEAINP
CCHHHHHHHHHHCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA