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The map label for this gene is gapA [H]

Identifier: 148827161

GI number: 148827161

Start: 452644

End: 453663

Strand: Direct

Name: gapA [H]

Synonym: CGSHiGG_02465

Alternate gene names: 148827161

Gene position: 452644-453663 (Clockwise)

Preceding gene: 148827151

Following gene: 148827162

Centisome position: 23.99

GC content: 40.69

Gene sequence:

>1020_bases
ATGGCAATTAAAATTGGTATCAATGGTTTTGGTCGTATCGGCCGTATCGTATTCCGTGCAGCACAACACCGTGATGACAT
TGAAGTTGTAGGTATTAACGACTTAATCGACGTTGAATACATGGCTTATATGTTGAAATATGATTCAACTCACGGTCGTT
TCGACGGCACTGTTGAAGTGAAAGATGGTAACTTAGTGGTTAATGGTAAAACTATCCGTGTCACTGCAGAACGTGATCCA
GCAAACTTAAACTGGGGTGCAATCGGTGTTGATATCGCTGTTGAAGCGACTGGTTTATTCTTAACTGATGAAACTGCTCG
TAAACATATCACTGCAGGCGCAAAAAAAGTTGTATTAACTGGCCCATCTAAAGATGCAACCCCTATGTTCGTTCGTGGTG
TAAACTTCAACGCATACGCAGGTCAAGATATCGTTTCTAACGCATCTTGTACAACAAACTGTTTAGCTCCTTTAGCACGT
GTTGTTCATGAAACTTTCGGTATCAAAGATGGTTTAATGACCACTGTTCACGCAACGACTGCAACTCAAAAAACTGTGGA
TGGTCCATCAGCTAAAGACTGGCGCGGCGGCCGCGGTGCATCACAAAACATCATTCCATCTTCAACAGGTGCAGCGAAAG
CTGTAGGTAAAGTATTACCTGCATTAAACGGTAAATTAACTGGTATGGCTTTCCGTGTTCCAACGCCAAACGTATCTGTT
GTTGATTTAACTGTTAATCTTGAAAAACCAGCTTCTTATGATGCAATCAAACAAGCAATCAAAGATGCAGCGGAAGGTAA
AACGTTCAATGGCGAATTAAAAGGCGTATTAGGTTACACTGAAGATGCTGTTGTTTCTACTGACTTCAACGGTTGTGCTT
TAACTTCTATATTTGATGCAGAAGCAGGTATCGCATTAACAGATTCTTTCGTTAAATTGGTATCTTGGTACGATAACGAA
ACGGGTTACTCAAACAAAGTATTAGACTTAGTAGCTCATATCTACAACTACAAAGGCTAA

Upstream 100 bases:

>100_bases
TAAAAATGCTCGTGCTATACTCTGTGCGTTGTCTTACTGAGTGAGCAGTATTACTCAAAGCAAACAGATTTGTTTAACTT
AAATAAAAGGTGAAAATCTT

Downstream 100 bases:

>100_bases
TTAAAAACTTTGAAAAAATTAACCGCTCTTCAGAGCGGTTTTTTATTATCTAGAATTTAATTTACGCTCTAAAAATGAAC
AAGGGATCACTAAAAATAAT

Product: glyceraldehyde-3-phosphate dehydrogenase

Products: NA

Alternate protein names: GAPDH [H]

Number of amino acids: Translated: 339; Mature: 338

Protein sequence:

>339_residues
MAIKIGINGFGRIGRIVFRAAQHRDDIEVVGINDLIDVEYMAYMLKYDSTHGRFDGTVEVKDGNLVVNGKTIRVTAERDP
ANLNWGAIGVDIAVEATGLFLTDETARKHITAGAKKVVLTGPSKDATPMFVRGVNFNAYAGQDIVSNASCTTNCLAPLAR
VVHETFGIKDGLMTTVHATTATQKTVDGPSAKDWRGGRGASQNIIPSSTGAAKAVGKVLPALNGKLTGMAFRVPTPNVSV
VDLTVNLEKPASYDAIKQAIKDAAEGKTFNGELKGVLGYTEDAVVSTDFNGCALTSIFDAEAGIALTDSFVKLVSWYDNE
TGYSNKVLDLVAHIYNYKG

Sequences:

>Translated_339_residues
MAIKIGINGFGRIGRIVFRAAQHRDDIEVVGINDLIDVEYMAYMLKYDSTHGRFDGTVEVKDGNLVVNGKTIRVTAERDP
ANLNWGAIGVDIAVEATGLFLTDETARKHITAGAKKVVLTGPSKDATPMFVRGVNFNAYAGQDIVSNASCTTNCLAPLAR
VVHETFGIKDGLMTTVHATTATQKTVDGPSAKDWRGGRGASQNIIPSSTGAAKAVGKVLPALNGKLTGMAFRVPTPNVSV
VDLTVNLEKPASYDAIKQAIKDAAEGKTFNGELKGVLGYTEDAVVSTDFNGCALTSIFDAEAGIALTDSFVKLVSWYDNE
TGYSNKVLDLVAHIYNYKG
>Mature_338_residues
AIKIGINGFGRIGRIVFRAAQHRDDIEVVGINDLIDVEYMAYMLKYDSTHGRFDGTVEVKDGNLVVNGKTIRVTAERDPA
NLNWGAIGVDIAVEATGLFLTDETARKHITAGAKKVVLTGPSKDATPMFVRGVNFNAYAGQDIVSNASCTTNCLAPLARV
VHETFGIKDGLMTTVHATTATQKTVDGPSAKDWRGGRGASQNIIPSSTGAAKAVGKVLPALNGKLTGMAFRVPTPNVSVV
DLTVNLEKPASYDAIKQAIKDAAEGKTFNGELKGVLGYTEDAVVSTDFNGCALTSIFDAEAGIALTDSFVKLVSWYDNET
GYSNKVLDLVAHIYNYKG

Specific function: Second phase of glycolysis; first step. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=334, Percent_Identity=63.7724550898204, Blast_Score=432, Evalue=1e-121,
Organism=Homo sapiens, GI7657116, Length=337, Percent_Identity=61.4243323442137, Blast_Score=417, Evalue=1e-117,
Organism=Escherichia coli, GI1788079, Length=334, Percent_Identity=82.934131736527, Blast_Score=571, Evalue=1e-164,
Organism=Escherichia coli, GI1789295, Length=334, Percent_Identity=39.2215568862275, Blast_Score=238, Evalue=4e-64,
Organism=Caenorhabditis elegans, GI32566163, Length=338, Percent_Identity=63.3136094674556, Blast_Score=413, Evalue=1e-116,
Organism=Caenorhabditis elegans, GI17568413, Length=338, Percent_Identity=63.3136094674556, Blast_Score=413, Evalue=1e-116,
Organism=Caenorhabditis elegans, GI17534677, Length=339, Percent_Identity=61.6519174041298, Blast_Score=408, Evalue=1e-114,
Organism=Caenorhabditis elegans, GI17534679, Length=339, Percent_Identity=61.0619469026549, Blast_Score=406, Evalue=1e-114,
Organism=Saccharomyces cerevisiae, GI6322409, Length=334, Percent_Identity=66.1676646706587, Blast_Score=437, Evalue=1e-123,
Organism=Saccharomyces cerevisiae, GI6321631, Length=334, Percent_Identity=66.1676646706587, Blast_Score=432, Evalue=1e-122,
Organism=Saccharomyces cerevisiae, GI6322468, Length=334, Percent_Identity=65.2694610778443, Blast_Score=430, Evalue=1e-121,
Organism=Drosophila melanogaster, GI17933600, Length=333, Percent_Identity=65.4654654654655, Blast_Score=429, Evalue=1e-120,
Organism=Drosophila melanogaster, GI18110149, Length=333, Percent_Identity=65.4654654654655, Blast_Score=429, Evalue=1e-120,
Organism=Drosophila melanogaster, GI85725000, Length=333, Percent_Identity=64.2642642642643, Blast_Score=425, Evalue=1e-119,
Organism=Drosophila melanogaster, GI22023983, Length=333, Percent_Identity=64.2642642642643, Blast_Score=425, Evalue=1e-119,
Organism=Drosophila melanogaster, GI19922412, Length=331, Percent_Identity=61.631419939577, Blast_Score=407, Evalue=1e-114,

Paralogues:

None

Copy number: 220 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 740 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1660 Molecules/Cell In: Growth Phase, Min

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 36080; Mature: 35949

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIKIGINGFGRIGRIVFRAAQHRDDIEVVGINDLIDVEYMAYMLKYDSTHGRFDGTVEV
CEEEEECCCCCHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHCCCCCCCCCCEEEE
KDGNLVVNGKTIRVTAERDPANLNWGAIGVDIAVEATGLFLTDETARKHITAGAKKVVLT
ECCCEEECCEEEEEEECCCCCCCCCCEEEEEEEEEEEEEEEECHHHHHHHCCCCCEEEEE
GPSKDATPMFVRGVNFNAYAGQDIVSNASCTTNCLAPLARVVHETFGIKDGLMTTVHATT
CCCCCCCCEEEEECCCCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECC
ATQKTVDGPSAKDWRGGRGASQNIIPSSTGAAKAVGKVLPALNGKLTGMAFRVPTPNVSV
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCEE
VDLTVNLEKPASYDAIKQAIKDAAEGKTFNGELKGVLGYTEDAVVSTDFNGCALTSIFDA
EEEEEECCCCCCHHHHHHHHHHHHCCCEECCCEEEEECCCCCEEEEECCCCEEEEEEECC
EAGIALTDSFVKLVSWYDNETGYSNKVLDLVAHIYNYKG
CCCEEEHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure 
AIKIGINGFGRIGRIVFRAAQHRDDIEVVGINDLIDVEYMAYMLKYDSTHGRFDGTVEV
EEEEECCCCCHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHCCCCCCCCCCEEEE
KDGNLVVNGKTIRVTAERDPANLNWGAIGVDIAVEATGLFLTDETARKHITAGAKKVVLT
ECCCEEECCEEEEEEECCCCCCCCCCEEEEEEEEEEEEEEEECHHHHHHHCCCCCEEEEE
GPSKDATPMFVRGVNFNAYAGQDIVSNASCTTNCLAPLARVVHETFGIKDGLMTTVHATT
CCCCCCCCEEEEECCCCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECC
ATQKTVDGPSAKDWRGGRGASQNIIPSSTGAAKAVGKVLPALNGKLTGMAFRVPTPNVSV
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCEE
VDLTVNLEKPASYDAIKQAIKDAAEGKTFNGELKGVLGYTEDAVVSTDFNGCALTSIFDA
EEEEEECCCCCCHHHHHHHHHHHHCCCEECCCEEEEECCCCCEEEEECCCCEEEEEEECC
EAGIALTDSFVKLVSWYDNETGYSNKVLDLVAHIYNYKG
CCCEEEHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]