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The map label for this gene is ydiD [C]

Identifier: 148827162

GI number: 148827162

Start: 453858

End: 455657

Strand: Direct

Name: ydiD [C]

Synonym: CGSHiGG_02470

Alternate gene names: 148827162

Gene position: 453858-455657 (Clockwise)

Preceding gene: 148827161

Following gene: 148827166

Centisome position: 24.05

GC content: 37.56

Gene sequence:

>1800_bases
ATGAATCTCGATCTCCATTTTGTTCATCGTATTCAACAACAAGCTAAAACTCGTACAAATATGACCGCACTTCGCTATAA
AGAACACGGCTTGTGGCGAGATATCTCTTGGAAAAACTTTCAAGAGCAACTCAATCAACTTTCTCGAGCATTGCTTGCTC
ACAATATTGGCGTACAAGATAAAATCGCCATTTTTGCCCATAATATGGAACGTTGGACAATCGCTGACATTGCGACCTTA
CAAATTCGCGCAATCACAGTACCTATTTACGCAACCAATACAGCCCAGCAAGCAGAATTTATCCTAAATCACGCCGATGT
AAAAATTCTCTTCGTCGGCGATCAAGAGCAATACGATCAAGCATTGGAAATTGCTCATCATTGTCCAAAATTACAAAAAA
TTGTGGCAATGAAATCCACCATTCAATTACAACAAGATCCTCTTTCTTGCACTTGGGAAAGTTTTATTAAAACAGGTTCA
AACGCCCAACAAGATGAACTAACCCAACGCTTAAACCAAAAACAATTATCGGATTTATTTACGATTATTTATACCTCAGG
CACAACGGGAGAGCCTAAAGGTGTCATGTTAGATTACGCCAATCTCGCTCACCAATTAGAAACACATGATCTTTCACTTA
ATGTGACAGATCAGGATATTTCACTTTCTTTTTTACCATTCTCTCATATTTTTGAACGAGCCTGGGCGGCTTATATTCTT
CATAGAGGTGCAATACTTTGCTATTTAGAAGACACCAATCAAGTGCGGTCAGCTTTAACGGAAATTCGACCAACCTTAAT
GTGTGCCGTACCACGTTTTTACGAAAAAATTTATGCAGCCGTGTTGGATAAAGTTCAAAAAGCACCAAAACTTCGCCAAA
TAATGTTTCATTGGGCAATTTCTGTAGGACAAAAACATTTTGATTTACGTGCGAATAACAAAGCTATTCCATTCTTATTG
AAGAAACAATTTGCTTTAGCGGATAAATTAGTGCTCTCAAAACTTCGTCAATTATTGGGGGGACGAATAAAAATGATGCC
TTGCGGAGGAGCAAAATTAGAACTGGCTATTGGGCTATTTTTCCACGCTATTGGTATCAACATCAAATTAGGCTATGGTA
TGACAGAAACAACTGCAACCGTTTCTTGCTGGCATGATTTCCAATTTAACCCAAATTCAATCGGCACACTGATGCCAAAA
GCGGAAGTGAAAATTGGGGAAAATAATGAAATCCTTGTGCGTGGCGGAATGGTGATGAAAGGCTATTACAAGAAGCCAGA
AGAAACGGCTCAAGCCTTCACCGAAGATGGTTTCTTAAAAACTGGTGATGCGGGAGAGTTTGACGAACAAGGCAATTTAT
TTATTACCGATCGTATCAAAGAATTAATGAAAACCTCAAACGGCAAATATATCGCACCACAATATATCGAAAGCAAAATC
GGTAAAGATAAATTTATCGAACAAATTGCGATCATCGCCGATGCGAAAAAATATGTATCTGCACTTATTGTGCCTTGCTT
TGATAGTTTGGAAGAATACGCTAAACAGCTCAATATTAAATATCATGACCGTTTAGAACTACTAAAAAATTCTGACATTC
TGAAAATGTTTGAGCAGCGTATTAATACGGTACAAAAAGAATTGGCTCATTTCGAGCAAGTAAAAAAATTCACGCTACTT
TCTCAAGCATTCAGCATTAAATTAGGCGAAATTACACCAACATTAAAATTGCGTAGAAAAGTGATTTTAGAACGTTATCG
CAAGCAAATTGAAGCAATGTATCATTCACAAGAAGCATAA

Upstream 100 bases:

>100_bases
AATAATTTAAAACAATCAATATTCTTCTAGCTTTTATTCCTATTTAAGATTATATTAGCGCACAACTGTTCGCTCAATGA
AAATCAAAAATAGGGTTAAT

Downstream 100 bases:

>100_bases
CTAAAAGGCTCTCAATTGAGAGCCTTTCTTTTCTAATTATTCAGGAAATTTTTCTTCTAAAATCAATGCAAGTCCATCTT
CATTATTGGTTACCGTAACC

Product: long chain fatty acid CoA ligase

Products: NA

Alternate protein names: Long-chain acyl-CoA synthetase; LACS [H]

Number of amino acids: Translated: 599; Mature: 599

Protein sequence:

>599_residues
MNLDLHFVHRIQQQAKTRTNMTALRYKEHGLWRDISWKNFQEQLNQLSRALLAHNIGVQDKIAIFAHNMERWTIADIATL
QIRAITVPIYATNTAQQAEFILNHADVKILFVGDQEQYDQALEIAHHCPKLQKIVAMKSTIQLQQDPLSCTWESFIKTGS
NAQQDELTQRLNQKQLSDLFTIIYTSGTTGEPKGVMLDYANLAHQLETHDLSLNVTDQDISLSFLPFSHIFERAWAAYIL
HRGAILCYLEDTNQVRSALTEIRPTLMCAVPRFYEKIYAAVLDKVQKAPKLRQIMFHWAISVGQKHFDLRANNKAIPFLL
KKQFALADKLVLSKLRQLLGGRIKMMPCGGAKLELAIGLFFHAIGINIKLGYGMTETTATVSCWHDFQFNPNSIGTLMPK
AEVKIGENNEILVRGGMVMKGYYKKPEETAQAFTEDGFLKTGDAGEFDEQGNLFITDRIKELMKTSNGKYIAPQYIESKI
GKDKFIEQIAIIADAKKYVSALIVPCFDSLEEYAKQLNIKYHDRLELLKNSDILKMFEQRINTVQKELAHFEQVKKFTLL
SQAFSIKLGEITPTLKLRRKVILERYRKQIEAMYHSQEA

Sequences:

>Translated_599_residues
MNLDLHFVHRIQQQAKTRTNMTALRYKEHGLWRDISWKNFQEQLNQLSRALLAHNIGVQDKIAIFAHNMERWTIADIATL
QIRAITVPIYATNTAQQAEFILNHADVKILFVGDQEQYDQALEIAHHCPKLQKIVAMKSTIQLQQDPLSCTWESFIKTGS
NAQQDELTQRLNQKQLSDLFTIIYTSGTTGEPKGVMLDYANLAHQLETHDLSLNVTDQDISLSFLPFSHIFERAWAAYIL
HRGAILCYLEDTNQVRSALTEIRPTLMCAVPRFYEKIYAAVLDKVQKAPKLRQIMFHWAISVGQKHFDLRANNKAIPFLL
KKQFALADKLVLSKLRQLLGGRIKMMPCGGAKLELAIGLFFHAIGINIKLGYGMTETTATVSCWHDFQFNPNSIGTLMPK
AEVKIGENNEILVRGGMVMKGYYKKPEETAQAFTEDGFLKTGDAGEFDEQGNLFITDRIKELMKTSNGKYIAPQYIESKI
GKDKFIEQIAIIADAKKYVSALIVPCFDSLEEYAKQLNIKYHDRLELLKNSDILKMFEQRINTVQKELAHFEQVKKFTLL
SQAFSIKLGEITPTLKLRRKVILERYRKQIEAMYHSQEA
>Mature_599_residues
MNLDLHFVHRIQQQAKTRTNMTALRYKEHGLWRDISWKNFQEQLNQLSRALLAHNIGVQDKIAIFAHNMERWTIADIATL
QIRAITVPIYATNTAQQAEFILNHADVKILFVGDQEQYDQALEIAHHCPKLQKIVAMKSTIQLQQDPLSCTWESFIKTGS
NAQQDELTQRLNQKQLSDLFTIIYTSGTTGEPKGVMLDYANLAHQLETHDLSLNVTDQDISLSFLPFSHIFERAWAAYIL
HRGAILCYLEDTNQVRSALTEIRPTLMCAVPRFYEKIYAAVLDKVQKAPKLRQIMFHWAISVGQKHFDLRANNKAIPFLL
KKQFALADKLVLSKLRQLLGGRIKMMPCGGAKLELAIGLFFHAIGINIKLGYGMTETTATVSCWHDFQFNPNSIGTLMPK
AEVKIGENNEILVRGGMVMKGYYKKPEETAQAFTEDGFLKTGDAGEFDEQGNLFITDRIKELMKTSNGKYIAPQYIESKI
GKDKFIEQIAIIADAKKYVSALIVPCFDSLEEYAKQLNIKYHDRLELLKNSDILKMFEQRINTVQKELAHFEQVKKFTLL
SQAFSIKLGEITPTLKLRRKVILERYRKQIEAMYHSQEA

Specific function: Unknown

COG id: COG1022

COG function: function code I; Long-chain acyl-CoA synthetases (AMP-forming)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATP-dependent AMP-binding enzyme family [H]

Homologues:

Organism=Homo sapiens, GI27477105, Length=626, Percent_Identity=27.4760383386581, Blast_Score=236, Evalue=5e-62,
Organism=Homo sapiens, GI42794760, Length=620, Percent_Identity=28.8709677419355, Blast_Score=226, Evalue=5e-59,
Organism=Homo sapiens, GI42794758, Length=620, Percent_Identity=28.8709677419355, Blast_Score=226, Evalue=5e-59,
Organism=Homo sapiens, GI42794756, Length=620, Percent_Identity=28.8709677419355, Blast_Score=226, Evalue=5e-59,
Organism=Homo sapiens, GI40807491, Length=593, Percent_Identity=28.3305227655987, Blast_Score=222, Evalue=7e-58,
Organism=Homo sapiens, GI83745141, Length=602, Percent_Identity=25.9136212624585, Blast_Score=222, Evalue=9e-58,
Organism=Homo sapiens, GI57165410, Length=595, Percent_Identity=29.0756302521008, Blast_Score=222, Evalue=1e-57,
Organism=Homo sapiens, GI57165412, Length=597, Percent_Identity=28.8107202680067, Blast_Score=221, Evalue=1e-57,
Organism=Homo sapiens, GI42794754, Length=584, Percent_Identity=26.541095890411, Blast_Score=184, Evalue=2e-46,
Organism=Homo sapiens, GI42794752, Length=584, Percent_Identity=26.541095890411, Blast_Score=184, Evalue=2e-46,
Organism=Homo sapiens, GI12669909, Length=611, Percent_Identity=25.69558101473, Blast_Score=169, Evalue=6e-42,
Organism=Homo sapiens, GI4758332, Length=611, Percent_Identity=25.69558101473, Blast_Score=169, Evalue=7e-42,
Organism=Escherichia coli, GI145693145, Length=511, Percent_Identity=21.9178082191781, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1788107, Length=493, Percent_Identity=23.3265720081136, Blast_Score=81, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17510401, Length=594, Percent_Identity=30.4713804713805, Blast_Score=238, Evalue=6e-63,
Organism=Caenorhabditis elegans, GI17541856, Length=598, Percent_Identity=29.2642140468227, Blast_Score=231, Evalue=6e-61,
Organism=Caenorhabditis elegans, GI17556552, Length=621, Percent_Identity=26.7310789049919, Blast_Score=229, Evalue=3e-60,
Organism=Caenorhabditis elegans, GI193204819, Length=623, Percent_Identity=26.9662921348315, Blast_Score=194, Evalue=8e-50,
Organism=Caenorhabditis elegans, GI17553312, Length=608, Percent_Identity=27.1381578947368, Blast_Score=181, Evalue=7e-46,
Organism=Caenorhabditis elegans, GI25147511, Length=616, Percent_Identity=25.3246753246753, Blast_Score=178, Evalue=7e-45,
Organism=Caenorhabditis elegans, GI17564090, Length=543, Percent_Identity=26.1510128913444, Blast_Score=169, Evalue=3e-42,
Organism=Caenorhabditis elegans, GI32563687, Length=482, Percent_Identity=24.2738589211618, Blast_Score=110, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17558820, Length=590, Percent_Identity=23.2203389830508, Blast_Score=107, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17559526, Length=491, Percent_Identity=25.8655804480652, Blast_Score=99, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI17531443, Length=323, Percent_Identity=27.8637770897833, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI71985884, Length=344, Percent_Identity=25.5813953488372, Blast_Score=79, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI133901848, Length=217, Percent_Identity=26.7281105990783, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17557194, Length=137, Percent_Identity=35.036496350365, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6322182, Length=469, Percent_Identity=28.7846481876333, Blast_Score=181, Evalue=2e-46,
Organism=Saccharomyces cerevisiae, GI6324893, Length=454, Percent_Identity=30.6167400881057, Blast_Score=179, Evalue=8e-46,
Organism=Saccharomyces cerevisiae, GI6320852, Length=578, Percent_Identity=25.0865051903114, Blast_Score=173, Evalue=6e-44,
Organism=Saccharomyces cerevisiae, GI6323903, Length=582, Percent_Identity=25.2577319587629, Blast_Score=172, Evalue=2e-43,
Organism=Drosophila melanogaster, GI281366413, Length=613, Percent_Identity=29.5269168026101, Blast_Score=242, Evalue=5e-64,
Organism=Drosophila melanogaster, GI24666501, Length=613, Percent_Identity=29.6900489396411, Blast_Score=241, Evalue=7e-64,
Organism=Drosophila melanogaster, GI24666497, Length=613, Percent_Identity=29.6900489396411, Blast_Score=241, Evalue=7e-64,
Organism=Drosophila melanogaster, GI17933690, Length=606, Percent_Identity=25.4125412541254, Blast_Score=223, Evalue=2e-58,
Organism=Drosophila melanogaster, GI19921316, Length=646, Percent_Identity=26.3157894736842, Blast_Score=214, Evalue=1e-55,
Organism=Drosophila melanogaster, GI62471689, Length=612, Percent_Identity=26.4705882352941, Blast_Score=182, Evalue=8e-46,
Organism=Drosophila melanogaster, GI62471681, Length=612, Percent_Identity=26.4705882352941, Blast_Score=181, Evalue=1e-45,
Organism=Drosophila melanogaster, GI62471687, Length=612, Percent_Identity=26.4705882352941, Blast_Score=181, Evalue=1e-45,
Organism=Drosophila melanogaster, GI24586634, Length=612, Percent_Identity=26.4705882352941, Blast_Score=181, Evalue=1e-45,
Organism=Drosophila melanogaster, GI22026970, Length=612, Percent_Identity=26.4705882352941, Blast_Score=181, Evalue=1e-45,
Organism=Drosophila melanogaster, GI62471679, Length=612, Percent_Identity=26.4705882352941, Blast_Score=181, Evalue=1e-45,
Organism=Drosophila melanogaster, GI62471683, Length=612, Percent_Identity=26.4705882352941, Blast_Score=181, Evalue=1e-45,
Organism=Drosophila melanogaster, GI62471685, Length=612, Percent_Identity=26.4705882352941, Blast_Score=181, Evalue=1e-45,
Organism=Drosophila melanogaster, GI24586636, Length=612, Percent_Identity=26.4705882352941, Blast_Score=181, Evalue=1e-45,
Organism=Drosophila melanogaster, GI21355181, Length=468, Percent_Identity=25.2136752136752, Blast_Score=106, Evalue=5e-23,
Organism=Drosophila melanogaster, GI24648257, Length=144, Percent_Identity=31.9444444444444, Blast_Score=70, Evalue=5e-12,
Organism=Drosophila melanogaster, GI20130357, Length=137, Percent_Identity=32.8467153284672, Blast_Score=69, Evalue=9e-12,
Organism=Drosophila melanogaster, GI281365686, Length=193, Percent_Identity=29.0155440414508, Blast_Score=69, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24648260, Length=125, Percent_Identity=33.6, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21358303, Length=193, Percent_Identity=29.0155440414508, Blast_Score=66, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020845
- InterPro:   IPR000873 [H]

Pfam domain/function: PF00501 AMP-binding [H]

EC number: =6.2.1.3 [H]

Molecular weight: Translated: 68605; Mature: 68605

Theoretical pI: Translated: 9.10; Mature: 9.10

Prosite motif: PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLDLHFVHRIQQQAKTRTNMTALRYKEHGLWRDISWKNFQEQLNQLSRALLAHNIGVQD
CCCCHHHHHHHHHHHHHHCCHHHEEEHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCC
KIAIFAHNMERWTIADIATLQIRAITVPIYATNTAQQAEFILNHADVKILFVGDQEQYDQ
EEEEEEECCCCEEEEEEEEEEEEEEEEEEEECCCHHHHHHHHCCCCEEEEEECCHHHHHH
ALEIAHHCPKLQKIVAMKSTIQLQQDPLSCTWESFIKTGSNAQQDELTQRLNQKQLSDLF
HHHHHHHCHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
TIIYTSGTTGEPKGVMLDYANLAHQLETHDLSLNVTDQDISLSFLPFSHIFERAWAAYIL
EEEEECCCCCCCCCEEEEHHHHHHHHHHCCEEEEEECCCCEEEECCHHHHHHHHHHHHHH
HRGAILCYLEDTNQVRSALTEIRPTLMCAVPRFYEKIYAAVLDKVQKAPKLRQIMFHWAI
HCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHH
SVGQKHFDLRANNKAIPFLLKKQFALADKLVLSKLRQLLGGRIKMMPCGGAKLELAIGLF
HHCCHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHH
FHAIGINIKLGYGMTETTATVSCWHDFQFNPNSIGTLMPKAEVKIGENNEILVRGGMVMK
HHHHEEEEEECCCCCCCCEEEEEEECCCCCCCCCCCCCCCCEEEECCCCEEEEECCEEEE
GYYKKPEETAQAFTEDGFLKTGDAGEFDEQGNLFITDRIKELMKTSNGKYIAPQYIESKI
CCCCCCHHHHHHHHCCCCEECCCCCCCCCCCCEEEHHHHHHHHHCCCCCEECHHHHHHHC
GKDKFIEQIAIIADAKKYVSALIVPCFDSLEEYAKQLNIKYHDRLELLKNSDILKMFEQR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHH
INTVQKELAHFEQVKKFTLLSQAFSIKLGEITPTLKLRRKVILERYRKQIEAMYHSQEA
HHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNLDLHFVHRIQQQAKTRTNMTALRYKEHGLWRDISWKNFQEQLNQLSRALLAHNIGVQD
CCCCHHHHHHHHHHHHHHCCHHHEEEHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCC
KIAIFAHNMERWTIADIATLQIRAITVPIYATNTAQQAEFILNHADVKILFVGDQEQYDQ
EEEEEEECCCCEEEEEEEEEEEEEEEEEEEECCCHHHHHHHHCCCCEEEEEECCHHHHHH
ALEIAHHCPKLQKIVAMKSTIQLQQDPLSCTWESFIKTGSNAQQDELTQRLNQKQLSDLF
HHHHHHHCHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
TIIYTSGTTGEPKGVMLDYANLAHQLETHDLSLNVTDQDISLSFLPFSHIFERAWAAYIL
EEEEECCCCCCCCCEEEEHHHHHHHHHHCCEEEEEECCCCEEEECCHHHHHHHHHHHHHH
HRGAILCYLEDTNQVRSALTEIRPTLMCAVPRFYEKIYAAVLDKVQKAPKLRQIMFHWAI
HCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHH
SVGQKHFDLRANNKAIPFLLKKQFALADKLVLSKLRQLLGGRIKMMPCGGAKLELAIGLF
HHCCHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHH
FHAIGINIKLGYGMTETTATVSCWHDFQFNPNSIGTLMPKAEVKIGENNEILVRGGMVMK
HHHHEEEEEECCCCCCCCEEEEEEECCCCCCCCCCCCCCCCEEEECCCCEEEEECCEEEE
GYYKKPEETAQAFTEDGFLKTGDAGEFDEQGNLFITDRIKELMKTSNGKYIAPQYIESKI
CCCCCCHHHHHHHHCCCCEECCCCCCCCCCCCEEEHHHHHHHHHCCCCCEECHHHHHHHC
GKDKFIEQIAIIADAKKYVSALIVPCFDSLEEYAKQLNIKYHDRLELLKNSDILKMFEQR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHH
INTVQKELAHFEQVKKFTLLSQAFSIKLGEITPTLKLRRKVILERYRKQIEAMYHSQEA
HHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]