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The map label for this gene is 148823764

Identifier: 148823764

GI number: 148823764

Start: 2906781

End: 2907725

Strand: Reverse

Name: 148823764

Synonym: TBFG_12589

Alternate gene names: NA

Gene position: 2907725-2906781 (Counterclockwise)

Preceding gene: 148823766

Following gene: 148823763

Centisome position: 65.72

GC content: 65.19

Gene sequence:

>945_bases
TTGTCAGCAGATAGCTCGTTGTCGTTGCCGTTGTCGGGCACTCACCGCTATCGAGTAACACACCGCACCGAATACCGCTA
CTCCGACGTGGTGACCAGCTCCTATGGCCGCGGGTTTCTCACGCCGCGGAATTCGCTGCGGCAGCGTTGTGTCGCACACC
GGCTGACCATCGACCCGGCCCCCGCCGACCGGTCCACCAGTCGCGACGGGTACGGCAACATCAGCTCCTATTTCCACGTC
ACCGAACCGCACCGCACCTTGACGATCACCAGCGATTCCATCGTCGACGTGTCCCCGCCGCCGCCCGGGCTTTACACCAG
CGGGCCGGCGCTGCAACCGTGGGAGGCGGCCCGGCCCGCCGGGCTGCCCGGATCGCTAGCCACCGAGTTCACCCTGGACT
TGAACCCGCCGGAGATCACCGATGCGGTGCGTGAGTACGCGGCTCCTAGCTTCCTGCCCAAACGCCCCCTGGTCGAGGTA
TTGCGCGATCTCGCGTCGCGGATCTACACCGACTTCACCTACCGCTCGGGTTCCACGACGATTTCCACAGGAGTCAACGA
GGTGCTGCTGGCCCGCGAAGGGGTATGCCAAGATTTCGCCAGGCTGGCGATCGCCTGCCTACGGGCCAACGGTTTGGCGG
CCTGTTATGTGTCGGGCTACCTGGCCACCGACCCGCCGCCCGGAAAGGATCGGATGATCGGCATCGACGCGACGCATGCC
TGGGCCTCGGTGTGGACTCCGCAGCAGCCCGGGCGGTTCGAGTGGCTGGGGCTGGATCCCACCAATGACCAGTTGGTCGA
CCAGCGCTACATCGTCGTGGGCCGCGGCCGCGACTACGCAGACGTGCCGCCGCTACGCGGCATCATCTACACCAACTCCG
AGAACAGTGTGATCGACGTTTCTGTCGATGTCGTGCCCTTCGAAGGTGATGCGCTGCATGCGTGA

Upstream 100 bases:

>100_bases
TTAATTGTGCTCCGGCTATGGTGCGCTTGGCGCCACATTGCGCGACGATCGCGCCGGACGAGCCGCCGGCGTGTGATGTG
ATCAGCCAGGAGGTAGCTTT

Downstream 100 bases:

>100_bases
CTTCCACTGTCCAAATTGCGGGCAGCGCCTGGCATTCGAGAACTCCGCCTGCCTGTCGTGCGGCAGCGCGCTGGGGTTTT
CTCTTGGGCGGATGGCGCTG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 314; Mature: 313

Protein sequence:

>314_residues
MSADSSLSLPLSGTHRYRVTHRTEYRYSDVVTSSYGRGFLTPRNSLRQRCVAHRLTIDPAPADRSTSRDGYGNISSYFHV
TEPHRTLTITSDSIVDVSPPPPGLYTSGPALQPWEAARPAGLPGSLATEFTLDLNPPEITDAVREYAAPSFLPKRPLVEV
LRDLASRIYTDFTYRSGSTTISTGVNEVLLAREGVCQDFARLAIACLRANGLAACYVSGYLATDPPPGKDRMIGIDATHA
WASVWTPQQPGRFEWLGLDPTNDQLVDQRYIVVGRGRDYADVPPLRGIIYTNSENSVIDVSVDVVPFEGDALHA

Sequences:

>Translated_314_residues
MSADSSLSLPLSGTHRYRVTHRTEYRYSDVVTSSYGRGFLTPRNSLRQRCVAHRLTIDPAPADRSTSRDGYGNISSYFHV
TEPHRTLTITSDSIVDVSPPPPGLYTSGPALQPWEAARPAGLPGSLATEFTLDLNPPEITDAVREYAAPSFLPKRPLVEV
LRDLASRIYTDFTYRSGSTTISTGVNEVLLAREGVCQDFARLAIACLRANGLAACYVSGYLATDPPPGKDRMIGIDATHA
WASVWTPQQPGRFEWLGLDPTNDQLVDQRYIVVGRGRDYADVPPLRGIIYTNSENSVIDVSVDVVPFEGDALHA
>Mature_313_residues
SADSSLSLPLSGTHRYRVTHRTEYRYSDVVTSSYGRGFLTPRNSLRQRCVAHRLTIDPAPADRSTSRDGYGNISSYFHVT
EPHRTLTITSDSIVDVSPPPPGLYTSGPALQPWEAARPAGLPGSLATEFTLDLNPPEITDAVREYAAPSFLPKRPLVEVL
RDLASRIYTDFTYRSGSTTISTGVNEVLLAREGVCQDFARLAIACLRANGLAACYVSGYLATDPPPGKDRMIGIDATHAW
ASVWTPQQPGRFEWLGLDPTNDQLVDQRYIVVGRGRDYADVPPLRGIIYTNSENSVIDVSVDVVPFEGDALHA

Specific function: Unknown

COG id: COG1305

COG function: function code E; Transglutaminase-like enzymes, putative cysteine proteases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To M.leprae ML0607

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y2569_MYCTU (P0A5G5)

Other databases:

- EMBL:   BX842580
- EMBL:   AE000516
- PIR:   H70723
- RefSeq:   NP_217085.1
- RefSeq:   NP_337144.1
- ProteinModelPortal:   P0A5G5
- SMR:   P0A5G5
- EnsemblBacteria:   EBMYCT00000001268
- EnsemblBacteria:   EBMYCT00000072172
- GeneID:   887783
- GeneID:   925669
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT2645
- KEGG:   mtu:Rv2569c
- TIGR:   MT2645
- TubercuList:   Rv2569c
- GeneTree:   EBGT00050000015447
- HOGENOM:   HBG553889
- OMA:   SHAWVSV
- ProtClustDB:   CLSK791928
- InterPro:   IPR013589
- InterPro:   IPR002931
- SMART:   SM00460

Pfam domain/function: PF08379 Bact_transglu_N; PF01841 Transglut_core

EC number: NA

Molecular weight: Translated: 34397; Mature: 34266

Theoretical pI: Translated: 5.90; Mature: 5.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSADSSLSLPLSGTHRYRVTHRTEYRYSDVVTSSYGRGFLTPRNSLRQRCVAHRLTIDPA
CCCCCCEECCCCCCEEEEEEECCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHEECCCC
PADRSTSRDGYGNISSYFHVTEPHRTLTITSDSIVDVSPPPPGLYTSGPALQPWEAARPA
CCCCCCCCCCCCCCCCEEEEECCCEEEEEECCCEEECCCCCCCCCCCCCCCCCHHHCCCC
GLPGSLATEFTLDLNPPEITDAVREYAAPSFLPKRPLVEVLRDLASRIYTDFTYRSGSTT
CCCCCCCEEEEEECCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCEEECCCCCE
ISTGVNEVLLAREGVCQDFARLAIACLRANGLAACYVSGYLATDPPPGKDRMIGIDATHA
ECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECEEECCCCCCCCCEEEEECHHH
WASVWTPQQPGRFEWLGLDPTNDQLVDQRYIVVGRGRDYADVPPLRGIIYTNSENSVIDV
HHCCCCCCCCCCEEEEECCCCCCCCCCCEEEEEECCCCCCCCCCCCEEEEECCCCCEEEE
SVDVVPFEGDALHA
EEEEEECCCCCCCC
>Mature Secondary Structure 
SADSSLSLPLSGTHRYRVTHRTEYRYSDVVTSSYGRGFLTPRNSLRQRCVAHRLTIDPA
CCCCCEECCCCCCEEEEEEECCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHEECCCC
PADRSTSRDGYGNISSYFHVTEPHRTLTITSDSIVDVSPPPPGLYTSGPALQPWEAARPA
CCCCCCCCCCCCCCCCEEEEECCCEEEEEECCCEEECCCCCCCCCCCCCCCCCHHHCCCC
GLPGSLATEFTLDLNPPEITDAVREYAAPSFLPKRPLVEVLRDLASRIYTDFTYRSGSTT
CCCCCCCEEEEEECCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCEEECCCCCE
ISTGVNEVLLAREGVCQDFARLAIACLRANGLAACYVSGYLATDPPPGKDRMIGIDATHA
ECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECEEECCCCCCCCCEEEEECHHH
WASVWTPQQPGRFEWLGLDPTNDQLVDQRYIVVGRGRDYADVPPLRGIIYTNSENSVIDV
HHCCCCCCCCCCEEEEECCCCCCCCCCCEEEEEECCCCCCCCCCCCEEEEECCCCCEEEE
SVDVVPFEGDALHA
EEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036