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The map label for this gene is argA [H]

Identifier: 148654047

GI number: 148654047

Start: 2794268

End: 2795590

Strand: Direct

Name: argA [H]

Synonym: PsycPRwf_2250

Alternate gene names: 148654047

Gene position: 2794268-2795590 (Clockwise)

Preceding gene: 148654045

Following gene: 148654049

Centisome position: 93.8

GC content: 47.85

Gene sequence:

>1323_bases
ATGATTGATACTGCTATGCCAAAAATAACGCCAGACTATGTTCATTGGTTTCGAAACTCAGCTCCTTATATCAATACCCA
TAGAGGCAAAACGTTCGTCATTATGTTTGGCGGCGAAGCTGTAAACCATCCTAATTTTAGCAATCTTATTCATGACTTTG
CGTTACTGCACAGTCTAGGTATTAACTTAGTCTTAGTGCATGGTGCACGGCCCCAGATTGAGAAGAACTTAGACAAATTG
GGTATAGACTCTCCACTACATAAAGACATTCGAGTCACGCCGCGCGAAGCCATGCCCGCCATTTTAGAAGCTGTGGGTGC
GATTCGCTTACAGATCGAAGCTCAGCTTTCGATGGGCCTTGCCAACTCCCCCATGTATGGCTCACGCATCGATGCTGTCT
CAGGCAACTTCGTTACTGCCAGACCTTATGGTGTCCGTGATGGCGTTGATTATCAAATGACCGGCGAAGTGCGCTCCATT
GATGTTGAAGCCATCAAAAACAATCTTATTCACAATCATATCGTCATCCTAGGCTCAATGGGCTACTCGGCCACCGGCGA
AGTATTTAACTTACTTGGAGAAGATGTGGCGCTTAAAGCGGCCGTTGCACTCAATGCCGATAAGCTGATTTTCTTAGGTA
ATGAGACGGGAATTAATGAAGAGGGTCGTTTGCTACACGCTATGATCCCTAATGAAGTGGACCGCTTCTTACGTGATCGT
GACTTGGACCGTGAGATTTATTACTTCTTATACTGCGCCGCTCAAGCTTGTCGTGCCGGTATCCACCGTACACACATCAT
CTCGTATGCTGAAGATGGGGCACTGCTAGAGGAGCTGTTTACTCGTGATGGCTCAGGCACACTCATTAGCCATGACCCTT
ATGAAGAGATTCGCCGTGCCACCATTGATGATGTGGTAGGCTTAATTGAGCTGCTCTCCCCTCTTGAGGAACAAGGCATT
TTAGTCCAGCGTTCACGTGAGCGCTTAGAGCAGGAGATTGAGCTGTATAGTGTGATCGAGCGCGATGGTATGATCTTGGG
CTGCGCAGCCTTGCATCCCTTAGATGACGAGTCAGCAGAAGTGGCGTCCATTGCCATTCACCCAGATTATCGTAATGGCA
GTCGTGGTGCAGATTTGCTCGCCTTTTTAGAGCAGCAAGCTCGCAGTCATGGTCTGCACAATCTATTTGCGTTAACCACC
CGTACCGCACACTGGTTTGTGGAGCAAGGTTTTATCGAAGTGAGCGCAGATCAATTGCCTGAGCCACGCCGCACCGCCTA
TCACAATGGTCGTAATTCAAAAGTATTCCAAAAAAGACTGTAG

Upstream 100 bases:

>100_bases
CTTACACCTAAAATAAAGATAGCCCAAGTTGGCATTTTTTGCTATCGTAAAAGCGTTTATTTCATTCCCTTATGCCTTAA
GCCTATTGTGATATTTTCAT

Downstream 100 bases:

>100_bases
CACTATTTTGCTACGACTGTAGACCATAAAAAATACCTGCTAATTAGCAGGTATTTTTTTGATGATTTTTGAAATTGTCA
AATCTGCCAATTATTAATTA

Product: N-acetylglutamate synthase

Products: NA

Alternate protein names: N-acetylglutamate synthase; AGS; NAGS [H]

Number of amino acids: Translated: 440; Mature: 440

Protein sequence:

>440_residues
MIDTAMPKITPDYVHWFRNSAPYINTHRGKTFVIMFGGEAVNHPNFSNLIHDFALLHSLGINLVLVHGARPQIEKNLDKL
GIDSPLHKDIRVTPREAMPAILEAVGAIRLQIEAQLSMGLANSPMYGSRIDAVSGNFVTARPYGVRDGVDYQMTGEVRSI
DVEAIKNNLIHNHIVILGSMGYSATGEVFNLLGEDVALKAAVALNADKLIFLGNETGINEEGRLLHAMIPNEVDRFLRDR
DLDREIYYFLYCAAQACRAGIHRTHIISYAEDGALLEELFTRDGSGTLISHDPYEEIRRATIDDVVGLIELLSPLEEQGI
LVQRSRERLEQEIELYSVIERDGMILGCAALHPLDDESAEVASIAIHPDYRNGSRGADLLAFLEQQARSHGLHNLFALTT
RTAHWFVEQGFIEVSADQLPEPRRTAYHNGRNSKVFQKRL

Sequences:

>Translated_440_residues
MIDTAMPKITPDYVHWFRNSAPYINTHRGKTFVIMFGGEAVNHPNFSNLIHDFALLHSLGINLVLVHGARPQIEKNLDKL
GIDSPLHKDIRVTPREAMPAILEAVGAIRLQIEAQLSMGLANSPMYGSRIDAVSGNFVTARPYGVRDGVDYQMTGEVRSI
DVEAIKNNLIHNHIVILGSMGYSATGEVFNLLGEDVALKAAVALNADKLIFLGNETGINEEGRLLHAMIPNEVDRFLRDR
DLDREIYYFLYCAAQACRAGIHRTHIISYAEDGALLEELFTRDGSGTLISHDPYEEIRRATIDDVVGLIELLSPLEEQGI
LVQRSRERLEQEIELYSVIERDGMILGCAALHPLDDESAEVASIAIHPDYRNGSRGADLLAFLEQQARSHGLHNLFALTT
RTAHWFVEQGFIEVSADQLPEPRRTAYHNGRNSKVFQKRL
>Mature_440_residues
MIDTAMPKITPDYVHWFRNSAPYINTHRGKTFVIMFGGEAVNHPNFSNLIHDFALLHSLGINLVLVHGARPQIEKNLDKL
GIDSPLHKDIRVTPREAMPAILEAVGAIRLQIEAQLSMGLANSPMYGSRIDAVSGNFVTARPYGVRDGVDYQMTGEVRSI
DVEAIKNNLIHNHIVILGSMGYSATGEVFNLLGEDVALKAAVALNADKLIFLGNETGINEEGRLLHAMIPNEVDRFLRDR
DLDREIYYFLYCAAQACRAGIHRTHIISYAEDGALLEELFTRDGSGTLISHDPYEEIRRATIDDVVGLIELLSPLEEQGI
LVQRSRERLEQEIELYSVIERDGMILGCAALHPLDDESAEVASIAIHPDYRNGSRGADLLAFLEQQARSHGLHNLFALTT
RTAHWFVEQGFIEVSADQLPEPRRTAYHNGRNSKVFQKRL

Specific function: Arginine biosynthesis; first step. [C]

COG id: COG0548

COG function: function code E; Acetylglutamate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 N-acetyltransferase domain [H]

Homologues:

Organism=Escherichia coli, GI1789181, Length=435, Percent_Identity=48.735632183908, Blast_Score=422, Evalue=1e-119,
Organism=Saccharomyces cerevisiae, GI6320913, Length=288, Percent_Identity=21.5277777777778, Blast_Score=64, Evalue=4e-11,

Paralogues:

None

Copy number: 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000182
- InterPro:   IPR016181
- InterPro:   IPR001048
- InterPro:   IPR010167 [H]

Pfam domain/function: PF00696 AA_kinase; PF00583 Acetyltransf_1 [H]

EC number: =2.3.1.1 [H]

Molecular weight: Translated: 49149; Mature: 49149

Theoretical pI: Translated: 5.65; Mature: 5.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDTAMPKITPDYVHWFRNSAPYINTHRGKTFVIMFGGEAVNHPNFSNLIHDFALLHSLG
CCCCCCCCCCHHHHHHHCCCCCEEEECCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCC
INLVLVHGARPQIEKNLDKLGIDSPLHKDIRVTPREAMPAILEAVGAIRLQIEAQLSMGL
CEEEEEECCCCHHHHHHHHCCCCCCCCCCCEECCHHHHHHHHHHHHHEEEEEEEEECCCC
ANSPMYGSRIDAVSGNFVTARPYGVRDGVDYQMTGEVRSIDVEAIKNNLIHNHIVILGSM
CCCCCCCCEECCCCCCEEEECCCCCCCCCCEEEECCEEEEEHHHHHHCCCCCEEEEEECC
GYSATGEVFNLLGEDVALKAAVALNADKLIFLGNETGINEEGRLLHAMIPNEVDRFLRDR
CCCCHHHHHHHHCCCHHHHHHEEECCCEEEEECCCCCCCCCCCEEEEECCHHHHHHHHHC
DLDREIYYFLYCAAQACRAGIHRTHIISYAEDGALLEELFTRDGSGTLISHDPYEEIRRA
CCCHHHHHHHHHHHHHHHCCCCHHEEEEECCCCHHHHHHHHCCCCCCEECCCCHHHHHHH
TIDDVVGLIELLSPLEEQGILVQRSRERLEQEIELYSVIERDGMILGCAALHPLDDESAE
HHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCC
VASIAIHPDYRNGSRGADLLAFLEQQARSHGLHNLFALTTRTAHWFVEQGFIEVSADQLP
EEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCEEECHHHCC
EPRRTAYHNGRNSKVFQKRL
CCHHHHHCCCCCCCHHHHCC
>Mature Secondary Structure
MIDTAMPKITPDYVHWFRNSAPYINTHRGKTFVIMFGGEAVNHPNFSNLIHDFALLHSLG
CCCCCCCCCCHHHHHHHCCCCCEEEECCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCC
INLVLVHGARPQIEKNLDKLGIDSPLHKDIRVTPREAMPAILEAVGAIRLQIEAQLSMGL
CEEEEEECCCCHHHHHHHHCCCCCCCCCCCEECCHHHHHHHHHHHHHEEEEEEEEECCCC
ANSPMYGSRIDAVSGNFVTARPYGVRDGVDYQMTGEVRSIDVEAIKNNLIHNHIVILGSM
CCCCCCCCEECCCCCCEEEECCCCCCCCCCEEEECCEEEEEHHHHHHCCCCCEEEEEECC
GYSATGEVFNLLGEDVALKAAVALNADKLIFLGNETGINEEGRLLHAMIPNEVDRFLRDR
CCCCHHHHHHHHCCCHHHHHHEEECCCEEEEECCCCCCCCCCCEEEEECCHHHHHHHHHC
DLDREIYYFLYCAAQACRAGIHRTHIISYAEDGALLEELFTRDGSGTLISHDPYEEIRRA
CCCHHHHHHHHHHHHHHHCCCCHHEEEEECCCCHHHHHHHHCCCCCCEECCCCHHHHHHH
TIDDVVGLIELLSPLEEQGILVQRSRERLEQEIELYSVIERDGMILGCAALHPLDDESAE
HHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCC
VASIAIHPDYRNGSRGADLLAFLEQQARSHGLHNLFALTTRTAHWFVEQGFIEVSADQLP
EEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCEEECHHHCC
EPRRTAYHNGRNSKVFQKRL
CCHHHHHCCCCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA