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The map label for this gene is tas [H]

Identifier: 148653662

GI number: 148653662

Start: 2320390

End: 2321430

Strand: Direct

Name: tas [H]

Synonym: PsycPRwf_1865

Alternate gene names: 148653662

Gene position: 2320390-2321430 (Clockwise)

Preceding gene: 148653661

Following gene: 148653665

Centisome position: 77.89

GC content: 47.45

Gene sequence:

>1041_bases
ATGAAATACACCACCCTCCCACAACTTGGTGACAAGGTTTCCAAAATTTGCTTGGGCACCATGACTTGGGGGCAGCAAAA
TACCGAAGATCAGGCGCATCAACAAATGGACTTTGCATTAAGCGAAGGCGTGAACTTCTGGGATACCGCAGAGATGTATC
CCTCACCGCCTGCCAAAGAAAAACAAGGGGATACCGAGCGTTTTATCGGCACTTGGTTTGCCAAGACCAAAAAGCGTAAT
GAGGTGATTTTAGCCAGTAAAATCTCTCCCATGGATTTCTTACGCGACGGTCAAACCCGTTTTAATGCCAAACACATCAG
TGACGCAATCGATGGCAACTTAAAGCGGTTGCAAACCGATCATATCGATGTGTACCAACTACATTGGCCTGAGCGTCAGA
CTAACTTTTTTAGCACCCGCGGCTATACCGAACAGATGGCGCAGCAAGATTTATCTCAGCTCACTCCATTTTTAGAGACC
ATCGAGGCCTTAAATGACGAGATTAAAAAAGGCCGCATTAGAGCTTGGGGACTCTCCAACGATACCGCTTGGGGCGTTAT
GCGCTATTTGTGGGAAGCTGAGAAAAATGGCTTAAAAGGCCCCATCACAGTCCAAAACCCTTATAGCTTATTGAATCGTT
TATATGAGGTTGGATTGGCAGAGGTGGCCCATCGTGAGAATGTCGGTCTGCTTGCCTACTCACCGCTTGGCTTTGGGGTA
TTATCTGGTAAATACCTAGACGGTAAACAGCCTGAGGGCGCACGTCTAACCATGTATGACCGCTTCCAACGTTACATCAA
TGACGAAGCAAAGTGGGCCACTGAGCAATATGCGCGTATCGCTACAGATGCCGGTCTAGATATGGCACAAATGGCCTTAG
CCTTCGTGAACAGCCGTCATTTTGTGACCAGTAATATCATTGGTGCCACCTCTATTGAGCAGTTGAAGTCTAATATTGAC
AGTGTTGATATTGAGCTAAGTGATGATGTGTTGCAGGCCATTGAGGCGGTGCATACTCAGCAGCCCAACCCGTCACCCTA
A

Upstream 100 bases:

>100_bases
ATGTGATGCAACTGATCTAAATAAGGACATCAATCATGTGGCCTATTTAGGTATAGCTAAACCTCTAATAAAACATACAA
CCACGAAAAAGGTATCGATT

Downstream 100 bases:

>100_bases
GCAACATAAACCGATAGCGGCACAAAAAAAGCCCTCAATCAGTGATTGAGAGCTTTTTTATTATGCAGCGTTTGGTCTTA
CTTATTGAGTTAACCGACTG

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 346; Mature: 346

Protein sequence:

>346_residues
MKYTTLPQLGDKVSKICLGTMTWGQQNTEDQAHQQMDFALSEGVNFWDTAEMYPSPPAKEKQGDTERFIGTWFAKTKKRN
EVILASKISPMDFLRDGQTRFNAKHISDAIDGNLKRLQTDHIDVYQLHWPERQTNFFSTRGYTEQMAQQDLSQLTPFLET
IEALNDEIKKGRIRAWGLSNDTAWGVMRYLWEAEKNGLKGPITVQNPYSLLNRLYEVGLAEVAHRENVGLLAYSPLGFGV
LSGKYLDGKQPEGARLTMYDRFQRYINDEAKWATEQYARIATDAGLDMAQMALAFVNSRHFVTSNIIGATSIEQLKSNID
SVDIELSDDVLQAIEAVHTQQPNPSP

Sequences:

>Translated_346_residues
MKYTTLPQLGDKVSKICLGTMTWGQQNTEDQAHQQMDFALSEGVNFWDTAEMYPSPPAKEKQGDTERFIGTWFAKTKKRN
EVILASKISPMDFLRDGQTRFNAKHISDAIDGNLKRLQTDHIDVYQLHWPERQTNFFSTRGYTEQMAQQDLSQLTPFLET
IEALNDEIKKGRIRAWGLSNDTAWGVMRYLWEAEKNGLKGPITVQNPYSLLNRLYEVGLAEVAHRENVGLLAYSPLGFGV
LSGKYLDGKQPEGARLTMYDRFQRYINDEAKWATEQYARIATDAGLDMAQMALAFVNSRHFVTSNIIGATSIEQLKSNID
SVDIELSDDVLQAIEAVHTQQPNPSP
>Mature_346_residues
MKYTTLPQLGDKVSKICLGTMTWGQQNTEDQAHQQMDFALSEGVNFWDTAEMYPSPPAKEKQGDTERFIGTWFAKTKKRN
EVILASKISPMDFLRDGQTRFNAKHISDAIDGNLKRLQTDHIDVYQLHWPERQTNFFSTRGYTEQMAQQDLSQLTPFLET
IEALNDEIKKGRIRAWGLSNDTAWGVMRYLWEAEKNGLKGPITVQNPYSLLNRLYEVGLAEVAHRENVGLLAYSPLGFGV
LSGKYLDGKQPEGARLTMYDRFQRYINDEAKWATEQYARIATDAGLDMAQMALAFVNSRHFVTSNIIGATSIEQLKSNID
SVDIELSDDVLQAIEAVHTQQPNPSP

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436969, Length=352, Percent_Identity=27.8409090909091, Blast_Score=122, Evalue=4e-28,
Organism=Homo sapiens, GI27436964, Length=353, Percent_Identity=27.4787535410765, Blast_Score=122, Evalue=4e-28,
Organism=Homo sapiens, GI4504825, Length=350, Percent_Identity=27.7142857142857, Blast_Score=121, Evalue=9e-28,
Organism=Homo sapiens, GI27436962, Length=353, Percent_Identity=27.1954674220963, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI27436966, Length=353, Percent_Identity=26.9121813031161, Blast_Score=118, Evalue=9e-27,
Organism=Homo sapiens, GI27436971, Length=358, Percent_Identity=25.9776536312849, Blast_Score=105, Evalue=6e-23,
Organism=Homo sapiens, GI41327764, Length=348, Percent_Identity=25.5747126436782, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI1789199, Length=350, Percent_Identity=49.4285714285714, Blast_Score=341, Evalue=3e-95,
Organism=Escherichia coli, GI87081735, Length=356, Percent_Identity=27.247191011236, Blast_Score=116, Evalue=3e-27,
Organism=Escherichia coli, GI1788070, Length=329, Percent_Identity=26.7477203647416, Blast_Score=88, Evalue=6e-19,
Organism=Escherichia coli, GI1789375, Length=337, Percent_Identity=25.8160237388724, Blast_Score=83, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6325169, Length=366, Percent_Identity=24.5901639344262, Blast_Score=86, Evalue=6e-18,
Organism=Saccharomyces cerevisiae, GI6323998, Length=346, Percent_Identity=23.6994219653179, Blast_Score=86, Evalue=9e-18,
Organism=Saccharomyces cerevisiae, GI6319958, Length=324, Percent_Identity=23.7654320987654, Blast_Score=86, Evalue=9e-18,
Organism=Saccharomyces cerevisiae, GI6319951, Length=345, Percent_Identity=22.6086956521739, Blast_Score=75, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6322615, Length=274, Percent_Identity=22.2627737226277, Blast_Score=71, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: NA

Molecular weight: Translated: 39236; Mature: 39236

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYTTLPQLGDKVSKICLGTMTWGQQNTEDQAHQQMDFALSEGVNFWDTAEMYPSPPAKE
CCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
KQGDTERFIGTWFAKTKKRNEVILASKISPMDFLRDGQTRFNAKHISDAIDGNLKRLQTD
CCCCHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHCCCHHHHHHHHHHHHCCCHHHHHCC
HIDVYQLHWPERQTNFFSTRGYTEQMAQQDLSQLTPFLETIEALNDEIKKGRIRAWGLSN
CCEEEEEECCCHHCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCC
DTAWGVMRYLWEAEKNGLKGPITVQNPYSLLNRLYEVGLAEVAHRENVGLLAYSPLGFGV
CHHHHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHH
LSGKYLDGKQPEGARLTMYDRFQRYINDEAKWATEQYARIATDAGLDMAQMALAFVNSRH
HCCCCCCCCCCCCCEEHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCC
FVTSNIIGATSIEQLKSNIDSVDIELSDDVLQAIEAVHTQQPNPSP
EEHHCCCCHHHHHHHHHCCCCEEEEECHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MKYTTLPQLGDKVSKICLGTMTWGQQNTEDQAHQQMDFALSEGVNFWDTAEMYPSPPAKE
CCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
KQGDTERFIGTWFAKTKKRNEVILASKISPMDFLRDGQTRFNAKHISDAIDGNLKRLQTD
CCCCHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHCCCHHHHHHHHHHHHCCCHHHHHCC
HIDVYQLHWPERQTNFFSTRGYTEQMAQQDLSQLTPFLETIEALNDEIKKGRIRAWGLSN
CCEEEEEECCCHHCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCC
DTAWGVMRYLWEAEKNGLKGPITVQNPYSLLNRLYEVGLAEVAHRENVGLLAYSPLGFGV
CHHHHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHH
LSGKYLDGKQPEGARLTMYDRFQRYINDEAKWATEQYARIATDAGLDMAQMALAFVNSRH
HCCCCCCCCCCCCCEEHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCC
FVTSNIIGATSIEQLKSNIDSVDIELSDDVLQAIEAVHTQQPNPSP
EEHHCCCCHHHHHHHHHCCCCEEEEECHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9560382; 9278503 [H]