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The map label for this gene is hflX [H]

Identifier: 148653665

GI number: 148653665

Start: 2324245

End: 2325690

Strand: Direct

Name: hflX [H]

Synonym: PsycPRwf_1868

Alternate gene names: 148653665

Gene position: 2324245-2325690 (Clockwise)

Preceding gene: 148653662

Following gene: 148653666

Centisome position: 78.02

GC content: 47.58

Gene sequence:

>1446_bases
TTGGATTATTTTGGTAGACATGAAGGTGGCGAACGCGCCATCTTAGTACACTTAGAGGTTAGACAAATCGCAGACCCAGA
TGATTTAGAGGAATTTAAATTATTGGTAGACTCTGCAGGTGCGCAGCAATTGGCGGTCATCACAGGGTCAAGACAGAAGC
CGGATGCCAAGTATTTTATTGGTAGTGGTAAAGCACAAGAGATTGCCGAGCAGGTACAGGCGCTTGAGGCAGATATTGTT
ATTTTTAACCACAGTTTGACGCCTTCACAAGAGCGTAACTTAGAGACCTTGCTGCAATGCCGCGTCTTAGATCGTACTGG
TCTAATTTTGGATATTTTCGCTCAGCGTGCCCGTACTTATGAAGGTAAATTGCAGGTGGAATTGGCTCAGCTTAACCACT
TGGCGACCCGCCTAGTACGCGGCTGGACCCATTTGGAGCGTCAAAAAGGGGGGATTGGTCTACGCGGACCAGGTGAAACC
CAGCTTGAAACCGATAGACGCTTGCTACAAATTCGAGTGTCTCAGTTAAAAGCACGCCTCGATAAAGTCAAACAGACCCG
AGCACAAGGCCGAGCCAAGCGTCAAAAATCAGATGTATTGACCATCTCATTGGTGGGCTATACCAACGCCGGCAAGTCCT
CTTTATTTAACCGCTTGGTCGATGAGGATATTTATGCTGCTGACCAGCTTTTTGCGACCTTAGATCCTACTTTAAGACGT
ATGGACTGGCAAGGCGTGGGCCGAGTGGTCTTGGTCGATACGGTAGGTTTCGTGCGTCATTTACCGCACGAGTTGGTAGA
GTCATTCCATGCAACTTTGGAGGAGACGCTAGAGGCTGACTTGTTATTACATGTGATTGACTCTTCAAGCCCCGACATGC
ATGAGCAAATCAAAGCAGTAAAAGAGGTATTGAGCGAAATTGATAACCATGTGCCTGTGCTCAATGTCTACAACAAGATT
GATATCACTGGTGAGCCGGCACAAATTAACTATAGTGGTCCTGGCGTGCCCAGTCGTGTGTATGTCTCCGCTAAGGCTGA
CCTTGGCATGAGTATGCTGCACACTGCCGTACAGCAGTTATTGACCGGTAAACTCAACACGTTTGAGATCACCCTACCCT
TCAATGCCGGCAATCTAAAAAATGAGCTATACCGCTTGGATGTGGTCGAACAAGAAAGCTATGATGAGCAGGGCCATGAA
GTACTTACCCTACGTCTGCCCTCTGATAAGTTGCAGCAATTGTTGGGTCAAGCCAATATTGATCCTCTCTCAGTGCTGCC
TAAAGACCAAGCTGAGCTGCTGATACCTACTCTTGAGCCTTTTGAAAAACAGCTAAAAGCCGATCAAGAAGCCAAAGCCG
CCCTACTGGATTTAGAGGCAGACTTTGAGGCGCCTGATTTTGAGCCAGTAGCAGATTGGCCTGAAGACGATGATATTCTG
CGCTAA

Upstream 100 bases:

>100_bases
CTTGAACAAACAGCTCAGCATAAACAAACAACCGAGCTTTTCGTTACAATAACCATTTTGGTAACAAGACCATTTAAATT
GACAACACAGGTGAATATTT

Downstream 100 bases:

>100_bases
GCTTTTTATTTTATCTTGACCGAGTGATGATGACATCCAACATAGGAGCCTTTAGGCTCCTATTTTTTTGTCAAAAATTC
AATTAATCTGGCTAACAATA

Product: HSR1-like GTP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 481; Mature: 481

Protein sequence:

>481_residues
MDYFGRHEGGERAILVHLEVRQIADPDDLEEFKLLVDSAGAQQLAVITGSRQKPDAKYFIGSGKAQEIAEQVQALEADIV
IFNHSLTPSQERNLETLLQCRVLDRTGLILDIFAQRARTYEGKLQVELAQLNHLATRLVRGWTHLERQKGGIGLRGPGET
QLETDRRLLQIRVSQLKARLDKVKQTRAQGRAKRQKSDVLTISLVGYTNAGKSSLFNRLVDEDIYAADQLFATLDPTLRR
MDWQGVGRVVLVDTVGFVRHLPHELVESFHATLEETLEADLLLHVIDSSSPDMHEQIKAVKEVLSEIDNHVPVLNVYNKI
DITGEPAQINYSGPGVPSRVYVSAKADLGMSMLHTAVQQLLTGKLNTFEITLPFNAGNLKNELYRLDVVEQESYDEQGHE
VLTLRLPSDKLQQLLGQANIDPLSVLPKDQAELLIPTLEPFEKQLKADQEAKAALLDLEADFEAPDFEPVADWPEDDDIL
R

Sequences:

>Translated_481_residues
MDYFGRHEGGERAILVHLEVRQIADPDDLEEFKLLVDSAGAQQLAVITGSRQKPDAKYFIGSGKAQEIAEQVQALEADIV
IFNHSLTPSQERNLETLLQCRVLDRTGLILDIFAQRARTYEGKLQVELAQLNHLATRLVRGWTHLERQKGGIGLRGPGET
QLETDRRLLQIRVSQLKARLDKVKQTRAQGRAKRQKSDVLTISLVGYTNAGKSSLFNRLVDEDIYAADQLFATLDPTLRR
MDWQGVGRVVLVDTVGFVRHLPHELVESFHATLEETLEADLLLHVIDSSSPDMHEQIKAVKEVLSEIDNHVPVLNVYNKI
DITGEPAQINYSGPGVPSRVYVSAKADLGMSMLHTAVQQLLTGKLNTFEITLPFNAGNLKNELYRLDVVEQESYDEQGHE
VLTLRLPSDKLQQLLGQANIDPLSVLPKDQAELLIPTLEPFEKQLKADQEAKAALLDLEADFEAPDFEPVADWPEDDDIL
R
>Mature_481_residues
MDYFGRHEGGERAILVHLEVRQIADPDDLEEFKLLVDSAGAQQLAVITGSRQKPDAKYFIGSGKAQEIAEQVQALEADIV
IFNHSLTPSQERNLETLLQCRVLDRTGLILDIFAQRARTYEGKLQVELAQLNHLATRLVRGWTHLERQKGGIGLRGPGET
QLETDRRLLQIRVSQLKARLDKVKQTRAQGRAKRQKSDVLTISLVGYTNAGKSSLFNRLVDEDIYAADQLFATLDPTLRR
MDWQGVGRVVLVDTVGFVRHLPHELVESFHATLEETLEADLLLHVIDSSSPDMHEQIKAVKEVLSEIDNHVPVLNVYNKI
DITGEPAQINYSGPGVPSRVYVSAKADLGMSMLHTAVQQLLTGKLNTFEITLPFNAGNLKNELYRLDVVEQESYDEQGHE
VLTLRLPSDKLQQLLGQANIDPLSVLPKDQAELLIPTLEPFEKQLKADQEAKAALLDLEADFEAPDFEPVADWPEDDDIL
R

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310133116, Length=239, Percent_Identity=36.4016736401674, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI310133118, Length=242, Percent_Identity=35.9504132231405, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI310124269, Length=221, Percent_Identity=37.10407239819, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI310124267, Length=221, Percent_Identity=37.10407239819, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI310124171, Length=221, Percent_Identity=37.10407239819, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI310124169, Length=221, Percent_Identity=37.10407239819, Blast_Score=118, Evalue=1e-26,
Organism=Escherichia coli, GI1790615, Length=417, Percent_Identity=57.7937649880096, Blast_Score=471, Evalue=1e-134,
Organism=Caenorhabditis elegans, GI17561038, Length=245, Percent_Identity=32.2448979591837, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24650079, Length=400, Percent_Identity=30.25, Blast_Score=127, Evalue=1e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 53915; Mature: 53915

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDYFGRHEGGERAILVHLEVRQIADPDDLEEFKLLVDSAGAQQLAVITGSRQKPDAKYFI
CCCCCCCCCCCEEEEEEEEHHHCCCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCCCEEE
GSGKAQEIAEQVQALEADIVIFNHSLTPSQERNLETLLQCRVLDRTGLILDIFAQRARTY
CCCHHHHHHHHHHHHHCCEEEEECCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHCC
EGKLQVELAQLNHLATRLVRGWTHLERQKGGIGLRGPGETQLETDRRLLQIRVSQLKARL
CCEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
DKVKQTRAQGRAKRQKSDVLTISLVGYTNAGKSSLFNRLVDEDIYAADQLFATLDPTLRR
HHHHHHHHHHHHHHHCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHH
MDWQGVGRVVLVDTVGFVRHLPHELVESFHATLEETLEADLLLHVIDSSSPDMHEQIKAV
CCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
KEVLSEIDNHVPVLNVYNKIDITGEPAQINYSGPGVPSRVYVSAKADLGMSMLHTAVQQL
HHHHHHHHCCCCEEEECCEEEECCCCCEEECCCCCCCCEEEEEECCCCCHHHHHHHHHHH
LTGKLNTFEITLPFNAGNLKNELYRLDVVEQESYDEQGHEVLTLRLPSDKLQQLLGQANI
HCCCCCEEEEEEECCCCCHHHHHEEEEEECCCCCCCCCCEEEEEECCHHHHHHHHCCCCC
DPLSVLPKDQAELLIPTLEPFEKQLKADQEAKAALLDLEADFEAPDFEPVADWPEDDDIL
CCCCCCCCCCCCEECCCHHHHHHHHCCCHHHHHHEEEEECCCCCCCCCCCCCCCCCCCCC
R
C
>Mature Secondary Structure
MDYFGRHEGGERAILVHLEVRQIADPDDLEEFKLLVDSAGAQQLAVITGSRQKPDAKYFI
CCCCCCCCCCCEEEEEEEEHHHCCCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCCCEEE
GSGKAQEIAEQVQALEADIVIFNHSLTPSQERNLETLLQCRVLDRTGLILDIFAQRARTY
CCCHHHHHHHHHHHHHCCEEEEECCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHCC
EGKLQVELAQLNHLATRLVRGWTHLERQKGGIGLRGPGETQLETDRRLLQIRVSQLKARL
CCEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
DKVKQTRAQGRAKRQKSDVLTISLVGYTNAGKSSLFNRLVDEDIYAADQLFATLDPTLRR
HHHHHHHHHHHHHHHCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHH
MDWQGVGRVVLVDTVGFVRHLPHELVESFHATLEETLEADLLLHVIDSSSPDMHEQIKAV
CCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
KEVLSEIDNHVPVLNVYNKIDITGEPAQINYSGPGVPSRVYVSAKADLGMSMLHTAVQQL
HHHHHHHHCCCCEEEECCEEEECCCCCEEECCCCCCCCEEEEEECCCCCHHHHHHHHHHH
LTGKLNTFEITLPFNAGNLKNELYRLDVVEQESYDEQGHEVLTLRLPSDKLQQLLGQANI
HCCCCCEEEEEEECCCCCHHHHHEEEEEECCCCCCCCCCEEEEEECCHHHHHHHHCCCCC
DPLSVLPKDQAELLIPTLEPFEKQLKADQEAKAALLDLEADFEAPDFEPVADWPEDDDIL
CCCCCCCCCCCCEECCCHHHHHHHHCCCHHHHHHEEEEECCCCCCCCCCCCCCCCCCCCC
R
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8248183; 7610040; 9278503; 2020545; 3040675 [H]