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The map label for this gene is cbl [H]

Identifier: 148653571

GI number: 148653571

Start: 2197692

End: 2198621

Strand: Direct

Name: cbl [H]

Synonym: PsycPRwf_1774

Alternate gene names: 148653571

Gene position: 2197692-2198621 (Clockwise)

Preceding gene: 148653568

Following gene: 148653572

Centisome position: 73.77

GC content: 47.63

Gene sequence:

>930_bases
ATGGCCATTGATGTCATCGTCAATCAAAGACATTTACAAATTCAGCTTAAACAGTTAGAGACGGTATGGCATACCGTAAT
TAATGGCTATAACTTAAGCCAAGCGGCGCAAGTGCTACATACTAGCCAATCAAGCCTGTCAAAGCACATCTCCGCTTTAG
AAAACCAATTAAAAGCCGAAGTCTTCGTGCGCCAAGGCAAACGCTTAACCGGACTGACCCCTGTCGGTGAAGCGCTACTG
CCCCATATTGAGGCAATTTTTACCGAAATTCGCACCATTGAGAATATCAGCCTTGATTACAACAACCCACAGACTGGTAC
ACTAACCCTAGCCACCACCCATACCCAAGCACGCTATGTACTGCCAGATATTATCAAGCAGTTTAAGCAGCAGTTCCCTA
AGGTGCAGCTGGTGCTACAGCAAGCCGATCCGCAAACGATTGCTAATATGGTCATTCGAGGTCAAGCCGATATCGGTATT
GCTACTGAAGCACTGCTACAAAACTCTTATCTGCGCTGCTACCGTTATTATGATTGGTCTCACCGTGTTATCGTGCCTAA
AGACCATGAACTGGCAGAATTAGACAGTATTGATTTGCCGACTCTTGCCAGCTATCCTTTGGTCACCTATCACGGCGGCT
TCACAGGTCGCGGCGCCATTGACAAGACCTTCCACGATGCCGGTCTTGAGCCTGAAATTGTCCTTGCTGCCCTCGATGCC
GATGTGATTAGTACCTATGTTGGGGCAGGTCTTGGTGTGGGTATTATCGCTGAAATGGCCTTTGAGCCTGGTCATTACCA
GAATCTGACTGCCATTCCTGTTGATCATTTTGGCCGCTTTACCAGTTGGATTGCGGTGCGAGATGACGCTGAGATTCGCC
ACTTTGGGCAGGCATTTATTCAGCTTTGCCAACAGCAATTTAGCAGCTAA

Upstream 100 bases:

>100_bases
TGCAGGCTCTTTATATGTTTAGTAGGCTAAATTTGCTTTGGCCACTGACGTGTTTTGAGTGAGCTTTTTAAGTGTTGCTG
AAGTGATATAGGAAAAATTT

Downstream 100 bases:

>100_bases
CTGCTCTTTGAAAACCCTCGGTTGATATCAAACTTGCGTTGACTCACAACCTTAATTTTCTTTTGATTGATACACGCTTT
TTACTCTTGTACCTTGATGG

Product: transcriptional regulator CysB-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 309; Mature: 308

Protein sequence:

>309_residues
MAIDVIVNQRHLQIQLKQLETVWHTVINGYNLSQAAQVLHTSQSSLSKHISALENQLKAEVFVRQGKRLTGLTPVGEALL
PHIEAIFTEIRTIENISLDYNNPQTGTLTLATTHTQARYVLPDIIKQFKQQFPKVQLVLQQADPQTIANMVIRGQADIGI
ATEALLQNSYLRCYRYYDWSHRVIVPKDHELAELDSIDLPTLASYPLVTYHGGFTGRGAIDKTFHDAGLEPEIVLAALDA
DVISTYVGAGLGVGIIAEMAFEPGHYQNLTAIPVDHFGRFTSWIAVRDDAEIRHFGQAFIQLCQQQFSS

Sequences:

>Translated_309_residues
MAIDVIVNQRHLQIQLKQLETVWHTVINGYNLSQAAQVLHTSQSSLSKHISALENQLKAEVFVRQGKRLTGLTPVGEALL
PHIEAIFTEIRTIENISLDYNNPQTGTLTLATTHTQARYVLPDIIKQFKQQFPKVQLVLQQADPQTIANMVIRGQADIGI
ATEALLQNSYLRCYRYYDWSHRVIVPKDHELAELDSIDLPTLASYPLVTYHGGFTGRGAIDKTFHDAGLEPEIVLAALDA
DVISTYVGAGLGVGIIAEMAFEPGHYQNLTAIPVDHFGRFTSWIAVRDDAEIRHFGQAFIQLCQQQFSS
>Mature_308_residues
AIDVIVNQRHLQIQLKQLETVWHTVINGYNLSQAAQVLHTSQSSLSKHISALENQLKAEVFVRQGKRLTGLTPVGEALLP
HIEAIFTEIRTIENISLDYNNPQTGTLTLATTHTQARYVLPDIIKQFKQQFPKVQLVLQQADPQTIANMVIRGQADIGIA
TEALLQNSYLRCYRYYDWSHRVIVPKDHELAELDSIDLPTLASYPLVTYHGGFTGRGAIDKTFHDAGLEPEIVLAALDAD
VISTYVGAGLGVGIIAEMAFEPGHYQNLTAIPVDHFGRFTSWIAVRDDAEIRHFGQAFIQLCQQQFSS

Specific function: May be an accessory regulatory protein within the cys regulon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788296, Length=296, Percent_Identity=41.2162162162162, Blast_Score=239, Evalue=2e-64,
Organism=Escherichia coli, GI1787530, Length=289, Percent_Identity=41.1764705882353, Blast_Score=220, Evalue=8e-59,
Organism=Escherichia coli, GI157672245, Length=207, Percent_Identity=29.4685990338164, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI145693105, Length=277, Percent_Identity=24.9097472924188, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI87082132, Length=138, Percent_Identity=29.7101449275362, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1787806, Length=295, Percent_Identity=24.0677966101695, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1790262, Length=297, Percent_Identity=27.6094276094276, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1788887, Length=297, Percent_Identity=25.9259259259259, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI1787601, Length=269, Percent_Identity=23.4200743494424, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1788481, Length=251, Percent_Identity=24.7011952191235, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1790399, Length=238, Percent_Identity=21.4285714285714, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI2367136, Length=228, Percent_Identity=21.4912280701754, Blast_Score=69, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34484; Mature: 34353

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIDVIVNQRHLQIQLKQLETVWHTVINGYNLSQAAQVLHTSQSSLSKHISALENQLKAE
CEEEEEECCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VFVRQGKRLTGLTPVGEALLPHIEAIFTEIRTIENISLDYNNPQTGTLTLATTHTQARYV
HHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCEEEEEEECCCCHHH
LPDIIKQFKQQFPKVQLVLQQADPQTIANMVIRGQADIGIATEALLQNSYLRCYRYYDWS
HHHHHHHHHHHCCHHEEHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHEEEEEECCC
HRVIVPKDHELAELDSIDLPTLASYPLVTYHGGFTGRGAIDKTFHDAGLEPEIVLAALDA
CEEECCCCCCHHHCCCCCCCCCCCCCEEEECCCCCCCCCCCCCHHHCCCCCEEEEEEHHH
DVISTYVGAGLGVGIIAEMAFEPGHYQNLTAIPVDHFGRFTSWIAVRDDAEIRHFGQAFI
HHHHHHHHCCCCHHHHHHHHCCCCCCCCEEECCHHHHCCHHHEEEECCCHHHHHHHHHHH
QLCQQQFSS
HHHHHHHCC
>Mature Secondary Structure 
AIDVIVNQRHLQIQLKQLETVWHTVINGYNLSQAAQVLHTSQSSLSKHISALENQLKAE
EEEEEECCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VFVRQGKRLTGLTPVGEALLPHIEAIFTEIRTIENISLDYNNPQTGTLTLATTHTQARYV
HHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCEEEEEEECCCCHHH
LPDIIKQFKQQFPKVQLVLQQADPQTIANMVIRGQADIGIATEALLQNSYLRCYRYYDWS
HHHHHHHHHHHCCHHEEHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHEEEEEECCC
HRVIVPKDHELAELDSIDLPTLASYPLVTYHGGFTGRGAIDKTFHDAGLEPEIVLAALDA
CEEECCCCCCHHHCCCCCCCCCCCCCEEEECCCCCCCCCCCCCHHHCCCCCEEEEEEHHH
DVISTYVGAGLGVGIIAEMAFEPGHYQNLTAIPVDHFGRFTSWIAVRDDAEIRHFGQAFI
HHHHHHHHCCCCHHHHHHHHCCCCCCCCEEECCHHHHCCHHHEEEECCCHHHHHHHHHHH
QLCQQQFSS
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8529872; 9097040; 9278503 [H]