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The map label for this gene is maeB [H]

Identifier: 148653073

GI number: 148653073

Start: 1562236

End: 1564575

Strand: Direct

Name: maeB [H]

Synonym: PsycPRwf_1269

Alternate gene names: 148653073

Gene position: 1562236-1564575 (Clockwise)

Preceding gene: 148653072

Following gene: 148653075

Centisome position: 52.44

GC content: 44.44

Gene sequence:

>2340_bases
ATGAGCGATAATACTTCAAATTCTATTCCTTCAGATCCTAATTCCATTAATGCAATGAACAAAGAGCAGTTTGAACAATC
CGCTTTGCATTATCATGAGCACCCAACACCTGGTAAGATCTCAGTTACCCCAACTAAGCAGATTGCTAACCAACATGACT
TAGCCTTGGCCTACTCTCCAGGGGTAGCTGTTCCTTGCTTAGAAATTCAACGAGATCCAAAGCTTGCGGCAAAATATACC
GCACGCAATAATCTAGTTGGTGTTATTACCAATGGTACGGCCGTACTGGGTCTAGGTAACATCGGTCCTTTGGCATCAAA
ACCGGTTATGGAAGGTAAGGGCGTATTATTTAAACGCTTTGCAGGTATCGATGTATTTGATATCGAAATTGATCAAAATG
ACCCTGACAAATTCATTGAAGCTGTGGCCTCTTTAGAGCCTACCTTTGGTGGTATCAACCTTGAGGACATCAAGGCGCCT
GAATGTTTCAAAATTGAGCGCGAACTACGTAAGCGCATGAACATTCCTGTATTCCATGATGACCAACATGGTACGTCAAT
CATTGTGGGCGCCGCTTTAATTAACGCTTTAAAACTGATCGACAAAAAAATTGAAGATATCAAAGTGGTGTGTTCTGGTG
CCGGTGCAGCCGCCATCTCATGCTTAGACTTAATTTGTGCGTTAGGCGTTCAACGCTCTAACATCTTTGTATCAGACTCA
CGCGGTATCATCTCTACCAAACGTGACAACTTAGATGAAAGCAAGCAGCGCTTTGCTCGTGACACAGAAGCCACAAGCCT
TAATGATGTGATGGACGATGTGGATATGTTCCTAGGCTTATCTATGCCAGGTATCTTAACCCCTGACATGATTAAGCGTA
TGGCTCGTGACCCTATTATCTTTGCACTGGCTAACCCTACTCCTGAAATTATGCCTGAAGTTGCGCATGCTGTTCGTGAT
GACGTTATCATGGCAACCGGTCGCTCAGACTATCCTAACCAAGTAAATAATGCCTTGTGCTTCCCTTATATCTTCCGTGG
TGCACTAGATGTGGGCGCAACCACAGTAAACGAAGAAATGAAGATTGCTTGTGTGCACGCTATTGCAGCCATGGCTCATG
TAGAAGCCACGCCACTGCAAGGCCAAAAATATGTGGATAGCTCTAAGATCTTTGGCCGCGAGTATCTGATCCCTGGCCCA
CTTGAGCCAAACTTAATCGTTGAGATTGCCTCTGCGGTAGCAAAAGCGGCCATGGATTCGGGTGTAGCCACACTACCGAT
TGATGACTTTAGTGCTTATCGTCAAAAACTTTCAGCCTTTGTGTATAACTCAGCCTTTGTAATGAAGCCTTTGTTTGCGC
GTGCCAAAGAAGATCCAAAACGTATTGTCTTCTGTGAAGGTGAAGATCCTGACGTACTGCGTGCAGTTCAGGTAGTGGTT
GATGAAGGCTTAGCTCAGCCAATCTTAGTGGGTCGCCCTGCAATTATTCAATCACAGATCAATGCCTTGAGCCTGCGTCT
AAAAGCAGGTGAAAACATTGAAATTGTAAACCAAGATGATGATCCACGCTATAAAGACTACTGGCAGACTTATTACGAGC
AAAATAAACGCAAGGGCGTCAGTATTGAACTTGCTCGCCGTGATGTGCGCCGTAAGACCACTCTAATCGGCTCTTTGTTG
GTCGAAAAAGGTGATGCTGATGGTATGATCTGTGGTACTTTCAGTCACTACAACTTGCACTTAAACTACGTAGAAAGAGT
CATTGGCAAGCTTGAGGGTGTTAAAAACTTCTACTCAATGAATGCCGTATTGATGCAAAACCGCAACTTGTTTATTGCCG
ATACCTATATTCATGAAGACCCAACCGCTGAGCAGTTGGCAGAAATGACAGTACTGGCTGTAGATCAAATGCGCCGCTTT
GGCATTACTCCACGTGTTGCTCTGCTTTCACACTCAAACTTCGGTACCTCTAACCGTGATAGCGCCATTAAAATGCGCAA
AGTGTATGAGCTGCTAAATGAAATGAATGTGGACTTTGAGTTTGATGGCGAAATGCATGGTGATTCAGCACTAGATGACC
GTATCCGTAATCAAGACTTCCCACACAGTGTGTTAAAAGGCCCAGCTAACTTGTTGATTATGCCAACCCTTGATGCCGCT
AACATTGCCTTTAATTTGTTAAAGACAGCTACAGGTAGTGCCACCATTGGTCCAATCCTATTAGGTGCCAGCAAGCCTGT
ACATATCTTAACGCCTTCTGCTACTGCTCGTCGTATTGTCAACATGACTGCCCTAGCGGTTACAGAAGCTCAAGATATCG
AAGCCAATGCAAAAAACTAA

Upstream 100 bases:

>100_bases
GTTAGTATAATAGCTAGAAAAATGCTAAAATATGAGGCGCACAATAACATTGAATCTCCGGTTACGGATTTCCTTTCTCA
AGAGATAATTGGTCTTAAAC

Downstream 100 bases:

>100_bases
TCTTAGCTTATAAGCCTTAAGTCAATAAAAAAGCCAGCAATCGCTGGCTTTTTTACTGATAGACCTAGACTAAAAAATTG
AGCCGTATTTTAGCAGTATG

Product: malic enzyme

Products: NA

Alternate protein names: NADP-ME [H]

Number of amino acids: Translated: 779; Mature: 778

Protein sequence:

>779_residues
MSDNTSNSIPSDPNSINAMNKEQFEQSALHYHEHPTPGKISVTPTKQIANQHDLALAYSPGVAVPCLEIQRDPKLAAKYT
ARNNLVGVITNGTAVLGLGNIGPLASKPVMEGKGVLFKRFAGIDVFDIEIDQNDPDKFIEAVASLEPTFGGINLEDIKAP
ECFKIERELRKRMNIPVFHDDQHGTSIIVGAALINALKLIDKKIEDIKVVCSGAGAAAISCLDLICALGVQRSNIFVSDS
RGIISTKRDNLDESKQRFARDTEATSLNDVMDDVDMFLGLSMPGILTPDMIKRMARDPIIFALANPTPEIMPEVAHAVRD
DVIMATGRSDYPNQVNNALCFPYIFRGALDVGATTVNEEMKIACVHAIAAMAHVEATPLQGQKYVDSSKIFGREYLIPGP
LEPNLIVEIASAVAKAAMDSGVATLPIDDFSAYRQKLSAFVYNSAFVMKPLFARAKEDPKRIVFCEGEDPDVLRAVQVVV
DEGLAQPILVGRPAIIQSQINALSLRLKAGENIEIVNQDDDPRYKDYWQTYYEQNKRKGVSIELARRDVRRKTTLIGSLL
VEKGDADGMICGTFSHYNLHLNYVERVIGKLEGVKNFYSMNAVLMQNRNLFIADTYIHEDPTAEQLAEMTVLAVDQMRRF
GITPRVALLSHSNFGTSNRDSAIKMRKVYELLNEMNVDFEFDGEMHGDSALDDRIRNQDFPHSVLKGPANLLIMPTLDAA
NIAFNLLKTATGSATIGPILLGASKPVHILTPSATARRIVNMTALAVTEAQDIEANAKN

Sequences:

>Translated_779_residues
MSDNTSNSIPSDPNSINAMNKEQFEQSALHYHEHPTPGKISVTPTKQIANQHDLALAYSPGVAVPCLEIQRDPKLAAKYT
ARNNLVGVITNGTAVLGLGNIGPLASKPVMEGKGVLFKRFAGIDVFDIEIDQNDPDKFIEAVASLEPTFGGINLEDIKAP
ECFKIERELRKRMNIPVFHDDQHGTSIIVGAALINALKLIDKKIEDIKVVCSGAGAAAISCLDLICALGVQRSNIFVSDS
RGIISTKRDNLDESKQRFARDTEATSLNDVMDDVDMFLGLSMPGILTPDMIKRMARDPIIFALANPTPEIMPEVAHAVRD
DVIMATGRSDYPNQVNNALCFPYIFRGALDVGATTVNEEMKIACVHAIAAMAHVEATPLQGQKYVDSSKIFGREYLIPGP
LEPNLIVEIASAVAKAAMDSGVATLPIDDFSAYRQKLSAFVYNSAFVMKPLFARAKEDPKRIVFCEGEDPDVLRAVQVVV
DEGLAQPILVGRPAIIQSQINALSLRLKAGENIEIVNQDDDPRYKDYWQTYYEQNKRKGVSIELARRDVRRKTTLIGSLL
VEKGDADGMICGTFSHYNLHLNYVERVIGKLEGVKNFYSMNAVLMQNRNLFIADTYIHEDPTAEQLAEMTVLAVDQMRRF
GITPRVALLSHSNFGTSNRDSAIKMRKVYELLNEMNVDFEFDGEMHGDSALDDRIRNQDFPHSVLKGPANLLIMPTLDAA
NIAFNLLKTATGSATIGPILLGASKPVHILTPSATARRIVNMTALAVTEAQDIEANAKN
>Mature_778_residues
SDNTSNSIPSDPNSINAMNKEQFEQSALHYHEHPTPGKISVTPTKQIANQHDLALAYSPGVAVPCLEIQRDPKLAAKYTA
RNNLVGVITNGTAVLGLGNIGPLASKPVMEGKGVLFKRFAGIDVFDIEIDQNDPDKFIEAVASLEPTFGGINLEDIKAPE
CFKIERELRKRMNIPVFHDDQHGTSIIVGAALINALKLIDKKIEDIKVVCSGAGAAAISCLDLICALGVQRSNIFVSDSR
GIISTKRDNLDESKQRFARDTEATSLNDVMDDVDMFLGLSMPGILTPDMIKRMARDPIIFALANPTPEIMPEVAHAVRDD
VIMATGRSDYPNQVNNALCFPYIFRGALDVGATTVNEEMKIACVHAIAAMAHVEATPLQGQKYVDSSKIFGREYLIPGPL
EPNLIVEIASAVAKAAMDSGVATLPIDDFSAYRQKLSAFVYNSAFVMKPLFARAKEDPKRIVFCEGEDPDVLRAVQVVVD
EGLAQPILVGRPAIIQSQINALSLRLKAGENIEIVNQDDDPRYKDYWQTYYEQNKRKGVSIELARRDVRRKTTLIGSLLV
EKGDADGMICGTFSHYNLHLNYVERVIGKLEGVKNFYSMNAVLMQNRNLFIADTYIHEDPTAEQLAEMTVLAVDQMRRFG
ITPRVALLSHSNFGTSNRDSAIKMRKVYELLNEMNVDFEFDGEMHGDSALDDRIRNQDFPHSVLKGPANLLIMPTLDAAN
IAFNLLKTATGSATIGPILLGASKPVHILTPSATARRIVNMTALAVTEAQDIEANAKN

Specific function: Unknown

COG id: COG0281

COG function: function code C; Malic enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family [H]

Homologues:

Organism=Homo sapiens, GI4505143, Length=342, Percent_Identity=25.1461988304094, Blast_Score=92, Evalue=2e-18,
Organism=Homo sapiens, GI62420882, Length=391, Percent_Identity=26.3427109974425, Blast_Score=88, Evalue=3e-17,
Organism=Homo sapiens, GI62420880, Length=391, Percent_Identity=26.3427109974425, Blast_Score=88, Evalue=3e-17,
Organism=Homo sapiens, GI239049447, Length=391, Percent_Identity=26.3427109974425, Blast_Score=88, Evalue=3e-17,
Organism=Homo sapiens, GI4505145, Length=368, Percent_Identity=25.8152173913043, Blast_Score=73, Evalue=1e-12,
Organism=Homo sapiens, GI270265879, Length=368, Percent_Identity=25.8152173913043, Blast_Score=72, Evalue=2e-12,
Organism=Escherichia coli, GI1788806, Length=753, Percent_Identity=58.9641434262948, Blast_Score=925, Evalue=0.0,
Organism=Escherichia coli, GI1788635, Length=319, Percent_Identity=31.974921630094, Blast_Score=137, Evalue=2e-33,
Organism=Escherichia coli, GI1788800, Length=319, Percent_Identity=28.5266457680251, Blast_Score=120, Evalue=3e-28,
Organism=Escherichia coli, GI87081919, Length=400, Percent_Identity=25.25, Blast_Score=77, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17537199, Length=398, Percent_Identity=26.8844221105528, Blast_Score=77, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6322823, Length=322, Percent_Identity=30.7453416149068, Blast_Score=92, Evalue=2e-19,
Organism=Drosophila melanogaster, GI281362672, Length=484, Percent_Identity=27.0661157024793, Blast_Score=102, Evalue=1e-21,
Organism=Drosophila melanogaster, GI281362674, Length=484, Percent_Identity=27.0661157024793, Blast_Score=102, Evalue=1e-21,
Organism=Drosophila melanogaster, GI21356279, Length=484, Percent_Identity=27.0661157024793, Blast_Score=101, Evalue=2e-21,
Organism=Drosophila melanogaster, GI78707242, Length=437, Percent_Identity=25.629290617849, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI78707238, Length=437, Percent_Identity=25.629290617849, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI78707240, Length=343, Percent_Identity=26.8221574344023, Blast_Score=86, Evalue=8e-17,
Organism=Drosophila melanogaster, GI24646388, Length=347, Percent_Identity=27.3775216138329, Blast_Score=84, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24646386, Length=347, Percent_Identity=27.3775216138329, Blast_Score=83, Evalue=7e-16,
Organism=Drosophila melanogaster, GI78707232, Length=403, Percent_Identity=24.0694789081886, Blast_Score=70, Evalue=6e-12,
Organism=Drosophila melanogaster, GI281363505, Length=363, Percent_Identity=24.5179063360882, Blast_Score=70, Evalue=6e-12,
Organism=Drosophila melanogaster, GI78707236, Length=363, Percent_Identity=24.5179063360882, Blast_Score=70, Evalue=6e-12,
Organism=Drosophila melanogaster, GI281363503, Length=363, Percent_Identity=24.5179063360882, Blast_Score=70, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015884
- InterPro:   IPR012301
- InterPro:   IPR012302
- InterPro:   IPR012188
- InterPro:   IPR016040
- InterPro:   IPR002505 [H]

Pfam domain/function: PF00390 malic; PF03949 Malic_M; PF01515 PTA_PTB [H]

EC number: =1.1.1.40 [H]

Molecular weight: Translated: 85476; Mature: 85345

Theoretical pI: Translated: 5.46; Mature: 5.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDNTSNSIPSDPNSINAMNKEQFEQSALHYHEHPTPGKISVTPTKQIANQHDLALAYSP
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEECCHHHHCCCCCEEEEECC
GVAVPCLEIQRDPKLAAKYTARNNLVGVITNGTAVLGLGNIGPLASKPVMEGKGVLFKRF
CCCCCCCCCCCCCCHHEEEECCCCEEEEEECCEEEEEECCCCCCCCCCCCCCCCHHHHHH
AGIDVFDIEIDQNDPDKFIEAVASLEPTFGGINLEDIKAPECFKIERELRKRMNIPVFHD
CCCEEEEEEECCCCHHHHHHHHHHCCCCCCCCCHHHCCCCHHHHHHHHHHHHCCCCEEEC
DQHGTSIIVGAALINALKLIDKKIEDIKVVCSGAGAAAISCLDLICALGVQRSNIFVSDS
CCCCCEEEHHHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHCCCCCCCEEEECC
RGIISTKRDNLDESKQRFARDTEATSLNDVMDDVDMFLGLSMPGILTPDMIKRMARDPII
CCEEECCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCEE
FALANPTPEIMPEVAHAVRDDVIMATGRSDYPNQVNNALCFPYIFRGALDVGATTVNEEM
EEECCCCHHHHHHHHHHHHCCEEEECCCCCCCHHHCCCEEHHHHHHHHHHCCCEECCCCH
KIACVHAIAAMAHVEATPLQGQKYVDSSKIFGREYLIPGPLEPNLIVEIASAVAKAAMDS
HHHHHHHHHHHHHCCCCCCCCCCCCCCHHHCCCCEECCCCCCCHHHHHHHHHHHHHHHHC
GVATLPIDDFSAYRQKLSAFVYNSAFVMKPLFARAKEDPKRIVFCEGEDPDVLRAVQVVV
CCEEECCHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHH
DEGLAQPILVGRPAIIQSQINALSLRLKAGENIEIVNQDDDPRYKDYWQTYYEQNKRKGV
HCCCCCCEECCCCHHHHHHHCEEEEEEECCCCEEEECCCCCCCHHHHHHHHHHHHCCCCC
SIELARRDVRRKTTLIGSLLVEKGDADGMICGTFSHYNLHLNYVERVIGKLEGVKNFYSM
EEEHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCEEEEEHHHHHHHHHHHHHHHHHHHH
NAVLMQNRNLFIADTYIHEDPTAEQLAEMTVLAVDQMRRFGITPRVALLSHSNFGTSNRD
CEEEEECCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCC
SAIKMRKVYELLNEMNVDFEFDGEMHGDSALDDRIRNQDFPHSVLKGPANLLIMPTLDAA
HHHHHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHCCCCCCHHHHCCCCCEEEEECCCHH
NIAFNLLKTATGSATIGPILLGASKPVHILTPSATARRIVNMTALAVTEAQDIEANAKN
HHHHHHHHHCCCCCEECEEEECCCCCEEEECCCHHHHHHHHHHHHEEECCCCCCCCCCC
>Mature Secondary Structure 
SDNTSNSIPSDPNSINAMNKEQFEQSALHYHEHPTPGKISVTPTKQIANQHDLALAYSP
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEECCHHHHCCCCCEEEEECC
GVAVPCLEIQRDPKLAAKYTARNNLVGVITNGTAVLGLGNIGPLASKPVMEGKGVLFKRF
CCCCCCCCCCCCCCHHEEEECCCCEEEEEECCEEEEEECCCCCCCCCCCCCCCCHHHHHH
AGIDVFDIEIDQNDPDKFIEAVASLEPTFGGINLEDIKAPECFKIERELRKRMNIPVFHD
CCCEEEEEEECCCCHHHHHHHHHHCCCCCCCCCHHHCCCCHHHHHHHHHHHHCCCCEEEC
DQHGTSIIVGAALINALKLIDKKIEDIKVVCSGAGAAAISCLDLICALGVQRSNIFVSDS
CCCCCEEEHHHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHCCCCCCCEEEECC
RGIISTKRDNLDESKQRFARDTEATSLNDVMDDVDMFLGLSMPGILTPDMIKRMARDPII
CCEEECCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCEE
FALANPTPEIMPEVAHAVRDDVIMATGRSDYPNQVNNALCFPYIFRGALDVGATTVNEEM
EEECCCCHHHHHHHHHHHHCCEEEECCCCCCCHHHCCCEEHHHHHHHHHHCCCEECCCCH
KIACVHAIAAMAHVEATPLQGQKYVDSSKIFGREYLIPGPLEPNLIVEIASAVAKAAMDS
HHHHHHHHHHHHHCCCCCCCCCCCCCCHHHCCCCEECCCCCCCHHHHHHHHHHHHHHHHC
GVATLPIDDFSAYRQKLSAFVYNSAFVMKPLFARAKEDPKRIVFCEGEDPDVLRAVQVVV
CCEEECCHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHH
DEGLAQPILVGRPAIIQSQINALSLRLKAGENIEIVNQDDDPRYKDYWQTYYEQNKRKGV
HCCCCCCEECCCCHHHHHHHCEEEEEEECCCCEEEECCCCCCCHHHHHHHHHHHHCCCCC
SIELARRDVRRKTTLIGSLLVEKGDADGMICGTFSHYNLHLNYVERVIGKLEGVKNFYSM
EEEHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCEEEEEHHHHHHHHHHHHHHHHHHHH
NAVLMQNRNLFIADTYIHEDPTAEQLAEMTVLAVDQMRRFGITPRVALLSHSNFGTSNRD
CEEEEECCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCC
SAIKMRKVYELLNEMNVDFEFDGEMHGDSALDDRIRNQDFPHSVLKGPANLLIMPTLDAA
HHHHHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHCCCCCCHHHHCCCCCEEEEECCCHH
NIAFNLLKTATGSATIGPILLGASKPVHILTPSATARRIVNMTALAVTEAQDIEANAKN
HHHHHHHHHCCCCCEECEEEECCCCCEEEECCCHHHHHHHHHHHHEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503; 36376 [H]